PART IV LABORATORY EXAMINATION
... When a heart muscle cell is stimulated, it depolarizes. As a result, the outside of the cell, in the area where the stimulation has occurred, becomes negative, while the inside of the cell becomes positive. This produces a difference in electrical voltage on the outside of the cell between the stimu ...
... When a heart muscle cell is stimulated, it depolarizes. As a result, the outside of the cell, in the area where the stimulation has occurred, becomes negative, while the inside of the cell becomes positive. This produces a difference in electrical voltage on the outside of the cell between the stimu ...
Recognizing and Managing Asymptomatic Left Ventricular Dysfunction: After Myocardial Infarction
... peptide is useful in detecting heart failure and requires only a single, rapidly performed blood test. In 2 studies,26,27 measurement of the level of brain natriuretic peptide was helpful in predicting LVSD and remodeling after myocardial infarction. Plasma levels of brain natriuretic peptide had a ...
... peptide is useful in detecting heart failure and requires only a single, rapidly performed blood test. In 2 studies,26,27 measurement of the level of brain natriuretic peptide was helpful in predicting LVSD and remodeling after myocardial infarction. Plasma levels of brain natriuretic peptide had a ...
the PDF - Heart Rhythm Society
... the statements. A single set of diagnostic criteria underlying the core statements would have great benefits for patient care and research. Although the Writing Group does not believe that a uniform criterion set can be achieved at this time, we encourage ECG vendors and electrocardiography research ...
... the statements. A single set of diagnostic criteria underlying the core statements would have great benefits for patient care and research. Although the Writing Group does not believe that a uniform criterion set can be achieved at this time, we encourage ECG vendors and electrocardiography research ...
Uncommon Conal Pathology in Complete Dextrotransposition of the
... The morphologic characteristics used to define classic complete dextroh-anspositionof the great arteries were found in 61 cases (88.4 percent) of a total of 69 cases of this malformation examined at necropsy in our hospital. They were lacking in the remaining eight cases (11.6 percent). The study of ...
... The morphologic characteristics used to define classic complete dextroh-anspositionof the great arteries were found in 61 cases (88.4 percent) of a total of 69 cases of this malformation examined at necropsy in our hospital. They were lacking in the remaining eight cases (11.6 percent). The study of ...
Effects of tumor necrosis factor-alpha on calcium movement in rat
... average normalized data. TNF-α 200 µg/L did not markedly influence activation properties. Half activation potential (V1/2) and slope factor (κ) were (-24.1±0.6) mV and (2.0±0.3) under control conditions, and at (-24.2±0.5) mV and (2.2±0.3) in the presence of TNFα 200 µg/L (Fig 4A, P>0.05). Steady-st ...
... average normalized data. TNF-α 200 µg/L did not markedly influence activation properties. Half activation potential (V1/2) and slope factor (κ) were (-24.1±0.6) mV and (2.0±0.3) under control conditions, and at (-24.2±0.5) mV and (2.2±0.3) in the presence of TNFα 200 µg/L (Fig 4A, P>0.05). Steady-st ...
Right Atrial Volume Index in Chronic Systolic Heart Failure and
... and specificity as provided by JMP 7.0 (SAS Institute, Cary, North Carolina). Spearman’s correlation coefficient was used to evaluate significant relationships between clinical and echocardiographic variables and RAVI. For linear regression analysis, a stepwise variable selection procedure was used ...
... and specificity as provided by JMP 7.0 (SAS Institute, Cary, North Carolina). Spearman’s correlation coefficient was used to evaluate significant relationships between clinical and echocardiographic variables and RAVI. For linear regression analysis, a stepwise variable selection procedure was used ...
left ventricular diastolic function part i: relaxing is easy
... Transmitral inflow: Flow occurs across the mitral valve when LA pressure exceeds LV pressure. Pulsed-wave Doppler echocardiography at the mitral valve leaflet tips in the midesophageal 4 chamber view creates a velocity vs. time spectral image representing the rapid filling phase, diastasis, and bloo ...
... Transmitral inflow: Flow occurs across the mitral valve when LA pressure exceeds LV pressure. Pulsed-wave Doppler echocardiography at the mitral valve leaflet tips in the midesophageal 4 chamber view creates a velocity vs. time spectral image representing the rapid filling phase, diastasis, and bloo ...
Noninvasive electrocardiographic imaging for cardiac
... studies: (i) normal activation and repolarization (subject N); (ii) right bundle branch (RBB) block (subject R), a conduction abnormality in which conduction through the right bundle branch of the specialized conduction system is blocked, and the impulse originating in the sinoatrial node is conduct ...
... studies: (i) normal activation and repolarization (subject N); (ii) right bundle branch (RBB) block (subject R), a conduction abnormality in which conduction through the right bundle branch of the specialized conduction system is blocked, and the impulse originating in the sinoatrial node is conduct ...
Management of patients with palpitations: a position paper from the
... Psychosomatic disorders that are most frequently associated with palpitations include anxiety, panic attacks, depression, and somatization, which can either induce sinus tachycardia or modify the patient’s subjective perception of a heartbeat that is otherwise normal or presents minimal irregulariti ...
... Psychosomatic disorders that are most frequently associated with palpitations include anxiety, panic attacks, depression, and somatization, which can either induce sinus tachycardia or modify the patient’s subjective perception of a heartbeat that is otherwise normal or presents minimal irregulariti ...
MRI in the assessment of ischaemic heart disease
... imaging, the diagnostic accuracy increased further (up to 93%).23 A normal stress CMR has a high negative predictive value in troponin-negative ACS.24 In an NSTEMI study, stress CMR reliably predicted significant coronary stenosis (sensitivity, 96%; specificity, 83%). Moreover, CMR assessment was supe ...
... imaging, the diagnostic accuracy increased further (up to 93%).23 A normal stress CMR has a high negative predictive value in troponin-negative ACS.24 In an NSTEMI study, stress CMR reliably predicted significant coronary stenosis (sensitivity, 96%; specificity, 83%). Moreover, CMR assessment was supe ...
Task Force Report Task Force on Sudden Cardiac Death of the
... centuries and throughout this time different authors have debated how to define it most appropriately. SCD is defined as follows: ‘Natural death due to cardiac causes, heralded by abrupt loss of consciousness within one hour of the onset of acute symptoms; preexisting heart disease may have been know ...
... centuries and throughout this time different authors have debated how to define it most appropriately. SCD is defined as follows: ‘Natural death due to cardiac causes, heralded by abrupt loss of consciousness within one hour of the onset of acute symptoms; preexisting heart disease may have been know ...
Amiodarone Supplants Lidocaine in ACLS and CPR Protocols
... Cardiac action potentials are divided into fast-response action potential and slowresponse action potential. Fast-response action potential, also known as nonpacemaker action potential, is found in nonnodal cardiomyocytes (atrial and ventricular myocytes, and Purkinje tissue). This action potential ...
... Cardiac action potentials are divided into fast-response action potential and slowresponse action potential. Fast-response action potential, also known as nonpacemaker action potential, is found in nonnodal cardiomyocytes (atrial and ventricular myocytes, and Purkinje tissue). This action potential ...
Myocardial contrast echocardiography is superior to - Heart
... Objectives: To compare intravenous myocardial contrast echocardiography (MCE) with other methods of assessing microvascular reperfusion for their ability to predict left ventricular function at one month after acute myocardial infarction. Design: 15 patients underwent primary percutaneous coronary a ...
... Objectives: To compare intravenous myocardial contrast echocardiography (MCE) with other methods of assessing microvascular reperfusion for their ability to predict left ventricular function at one month after acute myocardial infarction. Design: 15 patients underwent primary percutaneous coronary a ...
Normal Ventricular Repolarization Dispersion Range with Abrupt
... studies to distinguish normal and abnormal VRD patterns [8] and were used to quantifify pathological characteristics of VRD at high HR [9]. In addition, morphological indices have been exposed by others to improve the description of VRD, such as T-wave symmetry and T-wave area [10]. In this study, w ...
... studies to distinguish normal and abnormal VRD patterns [8] and were used to quantifify pathological characteristics of VRD at high HR [9]. In addition, morphological indices have been exposed by others to improve the description of VRD, such as T-wave symmetry and T-wave area [10]. In this study, w ...
Cold acclimation increases cardiac myofilament function and
... Cold acclimation of trout also affects transcript levels of troponin I (Alderman et al., 2012), troponin C (Genge et al., 2013) and sarcoplasmic reticulum Ca2+-ATPase (SERCA) (Korajoki and Vornanen, 2012), all of which are key proteins involved in contraction. Korajoki and Vornanen (Korajoki and Vor ...
... Cold acclimation of trout also affects transcript levels of troponin I (Alderman et al., 2012), troponin C (Genge et al., 2013) and sarcoplasmic reticulum Ca2+-ATPase (SERCA) (Korajoki and Vornanen, 2012), all of which are key proteins involved in contraction. Korajoki and Vornanen (Korajoki and Vor ...
The impact of age on cardiac excitation
... 1. Cardiovascular diseases most commonly occur in the elderly and are a frequent cause of disability or death. However, the effect of age itself on cardiac function is not well understood. 2. Studies in both human and animal hearts indicate that contractile function is unaffected by age while at res ...
... 1. Cardiovascular diseases most commonly occur in the elderly and are a frequent cause of disability or death. However, the effect of age itself on cardiac function is not well understood. 2. Studies in both human and animal hearts indicate that contractile function is unaffected by age while at res ...
The Hand1 and Hand2 transcription factors regulate
... Generation of floxed Hand1 alleles To create a conditional Hand1-null allele, we flanked the first exon of the mouse Hand1 gene with loxP sites by homologous recombination in ES cells (Fig. 1A). Our targeting strategy introduced a neomycin resistance cassette into the 5′untranslated region of Hand1. ...
... Generation of floxed Hand1 alleles To create a conditional Hand1-null allele, we flanked the first exon of the mouse Hand1 gene with loxP sites by homologous recombination in ES cells (Fig. 1A). Our targeting strategy introduced a neomycin resistance cassette into the 5′untranslated region of Hand1. ...
Evaluation of Melissa officinalis (Lemon Balm) Effects on Heart
... and consequently ventricular tachycardia or ventricular fibrillation. Therefore, prolongation of QRS, JT, QTc and TpTe intervals following Melissa officinalis pretreatment, can be a double-edged sword, indicating antiarrhythmic or proarrhythmic effect. If the proarrhythmic effect be dominant, it cou ...
... and consequently ventricular tachycardia or ventricular fibrillation. Therefore, prolongation of QRS, JT, QTc and TpTe intervals following Melissa officinalis pretreatment, can be a double-edged sword, indicating antiarrhythmic or proarrhythmic effect. If the proarrhythmic effect be dominant, it cou ...
Contractile properties of thermally acclimated trout heart
... atrioventricular node (Katz, 1992) and by rapid contraction kinetics of the atrial muscle. Although atrial contraction exerts significant regulatory function in ventricular contractility through the Frank–Starling mechanism, its role in ventricular ...
... atrioventricular node (Katz, 1992) and by rapid contraction kinetics of the atrial muscle. Although atrial contraction exerts significant regulatory function in ventricular contractility through the Frank–Starling mechanism, its role in ventricular ...
Brugada Syndrome - Circulation: Arrhythmia and Electrophysiology
... rugada syndrome (BrS) has originally been described as an autosomal-dominant inherited arrhythmic disorder characterized by ST elevation with successive negative T wave in the right precordial leads without structural cardiac abnormalities.1,2 Patients are at risk for sudden cardiac death (SCD) due ...
... rugada syndrome (BrS) has originally been described as an autosomal-dominant inherited arrhythmic disorder characterized by ST elevation with successive negative T wave in the right precordial leads without structural cardiac abnormalities.1,2 Patients are at risk for sudden cardiac death (SCD) due ...
Imaging Guidelines for Nuclear Cardiology
... 6. Beat selection. A hard copy of the time-activity curve should be generated by the technologist during processing so one may confirm that the appropriate beats have been selected for inclusion in the representative cycle. Unless the number of beats is very limited, one should preferably select bea ...
... 6. Beat selection. A hard copy of the time-activity curve should be generated by the technologist during processing so one may confirm that the appropriate beats have been selected for inclusion in the representative cycle. Unless the number of beats is very limited, one should preferably select bea ...
Electrophysiology Circulation: Arrhythmia &
... in 142 patients (mean age 69±11 years, 101 male). Of those, 48 patients died during follow- ...
... in 142 patients (mean age 69±11 years, 101 male). Of those, 48 patients died during follow- ...
Module I E.C.G. RHYTHM INTERPRETATION
... Anatomy and Physiology The cardiac conduction system is comprised of specialized tissues that unlike muscle tissue located elsewhere in the body can 1: generate electrical impulses (automaticity) and 2: conduct electrical impulses (conductivity). The cardiac muscle tissue is similar to other tissue ...
... Anatomy and Physiology The cardiac conduction system is comprised of specialized tissues that unlike muscle tissue located elsewhere in the body can 1: generate electrical impulses (automaticity) and 2: conduct electrical impulses (conductivity). The cardiac muscle tissue is similar to other tissue ...
Changes in Intracellular Na+ following Enhancement of Late Na+
... tissue) a change in the height of the plateau of the action potential [17,31]. Prominent, but more slowly developing changes in action potential waveform have also been observed [21,32]. At present, the predominant working hypothesis with respect to the sequelae that may lead to the pro-arrhythmic v ...
... tissue) a change in the height of the plateau of the action potential [17,31]. Prominent, but more slowly developing changes in action potential waveform have also been observed [21,32]. At present, the predominant working hypothesis with respect to the sequelae that may lead to the pro-arrhythmic v ...
Editorials Original Articles - Circulation: Arrhythmia and
... Esteban W. Rivarola, MD, PhD; Denise Hachul, MD, PhD; Tan Wu, MD; Cristiano Pisani, MD; Carina Hardy, MD; Fabrizio Raimundi, BS; Sissy Melo, MD, PhD; Francisco Darrieux, MD, PhD; Mauricio Scanavacca, MD, PhD · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · ...
... Esteban W. Rivarola, MD, PhD; Denise Hachul, MD, PhD; Tan Wu, MD; Cristiano Pisani, MD; Carina Hardy, MD; Fabrizio Raimundi, BS; Sissy Melo, MD, PhD; Francisco Darrieux, MD, PhD; Mauricio Scanavacca, MD, PhD · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · ...
Ventricular fibrillation
Ventricular fibrillation (V-fib or VF) is a condition in which there is uncoordinated contraction of the cardiac muscle of the ventricles in the heart, making them quiver rather than contract properly. Ventricular fibrillation is the most commonly identified arrhythmia in cardiac arrest patients. While there is some activity, the lay person is usually unable to detect it by palpating (feeling) the major pulse points of the carotid and femoral arteries. Such an arrhythmia is only confirmed by electrocardiography. Ventricular fibrillation is a medical emergency that requires prompt Advanced Life Support interventions. If this arrhythmia continues for more than a few seconds, it will likely degenerate further into asystole (""flatline""). This condition results in cardiogenic shock and cessation of effective blood circulation. As a consequence, sudden cardiac death (SCD) will result in a matter of minutes. If the patient is not revived after a sufficient period (within roughly 5 minutes at room temperature), the patient could sustain irreversible brain damage and possibly become brain-dead, due to the effects of cerebral hypoxia. On the other hand, death often occurs if sinus rhythm is not restored within 90 seconds of the onset of VF, especially if it has degenerated further into asystole.