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A Direct Examination of Papillary Muscle Function in the Canine Left
A Direct Examination of Papillary Muscle Function in the Canine Left

... that papillary muscle contraction could be specifically identified in the femoral artery pressure curve.· While it appears now that these conclusions far outstripped the sensitivity of the instruments used and the actual data shown, they did have the salutary effect of promoting investigation in thi ...
Characterization and Modeling of the Purkinje System for Biophysical Simulations
Characterization and Modeling of the Purkinje System for Biophysical Simulations

... the excitation-contraction function of the heart ventricles. The electrical impulse originates in the sino-atrial node (SAN), the natural pacemaker, located in the right atrium of the heart. From the SAN it advances to the atrio-ventricular node (AVN), which electrically delays the impulse and conne ...
Electrocardiographic changes associated with serum electrolyte
Electrocardiographic changes associated with serum electrolyte

... unusual electrocardiographic patterns. 51 Currens and Crawford 52 studied the electrocardiographic tracings from patients with a variety of diseases in which alterations of electrolyte balance including potassium metabolism were apparent. In this study there was a lack of correlation between the ele ...
Spatiotemporal electrophysiological changes in a murine ablation
Spatiotemporal electrophysiological changes in a murine ablation

... n ¼ 10) at post-ablation Day 7 (0.39 + 0.09, n ¼ 7, P ¼ 0.0006 and 0.50 + 0.08, n ¼ 7, P ¼ 0.002, respectively), and 30 (0.62 + 0.12, n ¼ 10, P ¼ 0.014 and 0.61 + 0.06, n ¼ 10, P ¼ 0.002 respectively). Sixty days post-ablation average EGM amplitude at the border and 4 mm away returned to baseline le ...
Electrophysiological properties of rainbow trout cardiac myocytes in
Electrophysiological properties of rainbow trout cardiac myocytes in

... changes during the culture and some of the electrophysiological changes seem to be closely associated with ultrastructural transformations induced by culture conditions (16). For example, the extensive ttubular system of the adult cardiac myocytes is practically lost during cell culture, resulting i ...
Document
Document

... and matrix 5 256 3 96).1,2 Three short axis images were acquired for the LV base, mid-ventricle and apex. The basal slice was positioned parallel to the base of the heart and distal to the LV outflow tract. Basal, mid-ventricular and apical slices were positioned 15–20 mm apart, depending on the hear ...
Editorial Review Abnormalities of the coronary circulation
Editorial Review Abnormalities of the coronary circulation

... Hypertension, the most frequent cause of left ventricular hypertrophy, is associated with an increased risk of coronary atheroma [5], yet left ventricular hypertrophy defined by echocardiography is the most powerful independent predictor of mortality in multivariate analysis [6], more powerful even ...
Review Article Frequency Analysis Of Atrial Fibrillation
Review Article Frequency Analysis Of Atrial Fibrillation

... significant statistical and subsequently scientific errors, especially if the baseline frequency exhibits large inter-individual variability. The reason is, that the same frequency difference results in larger cycle length differences for low frequencies compared to high frequencies. Method Validati ...
Cardiac αVβ3 integrin expression following acute - Heart
Cardiac αVβ3 integrin expression following acute - Heart

... restoration of myocardial integrity.2 In some circumstances, maladaptive persistent processes may encourage remodelling and scarring to extend into the myocardium long after the initial causative injury. This may lead to progressive ventricular dilatation, ventricular dysfunction and heart failure. ...
PDF - Circulation: Cardiovascular Imaging
PDF - Circulation: Cardiovascular Imaging

... deformation parameters alone do not account for the variable mechanical load caused by LV pressure (LVP) variations.1 Regional myocardial work, however, has been shown to reflect regional metabolic demand and oxygen consumption and do therefore provide a more comprehensive assessment of myocardial f ...
Assessment of strain and strain rate by two
Assessment of strain and strain rate by two

... strain rate in these animals. This study was therefore performed to compare the strain and strain rate deformation parameters assessed by STI with those of tissue Doppler imaging and conductance catheter measurements in chronic murine models of LV ...
Emerging mechanisms of T-tubule remodelling in heart failure
Emerging mechanisms of T-tubule remodelling in heart failure

... ‘Ca2+ spikes’, were visualized at individual T-tubule/SR junctions. At a full-blown depolarization (e.g. depolarization to 0 mV from resting membrane potential), Ca2+ spikes occur almost at the same time from all different T-tubule/SR junctions, revealing the highly synchronous nature of Ca2+ releas ...
Print - Circulation
Print - Circulation

... Key Words: arrhythmia 䡲 cardioversion 䡲 electrical stimulation 䡲 electrocardiography 䡲 electrophysiology ...
Current burden of sudden cardiac death: Multiple source
Current burden of sudden cardiac death: Multiple source

... U.S. Centers for Disease Control and Prevention have published an estimate of the annual incidence of SCD in the U.S. based on death certificate data, and this previously described methodology was employed (2). Death certificate data were reviewed at the Oregon State Health Division on a quarterly b ...
Advances in Arrhythmia and Electrophysiology
Advances in Arrhythmia and Electrophysiology

... procedural end point derives from studies including patients with infarct-related VT (Table 2). Early experiences with catheter ablation in this clinical setting reported a significant association between noninducibility at the end of the procedure and VT-free survival.12–16 Subsequent studies inclu ...
Electrical Impedance of Normal and Ischemic Myocardium. Role on and Ventricular Arrhythmias.
Electrical Impedance of Normal and Ischemic Myocardium. Role on and Ventricular Arrhythmias.

... mortality in Catalonia in 1994. Among these deaths, 27% were due to ischemic heart disease 1. Myocardial ischemia results in four basic clinical syndromes which are angina pectoris, myocardial infarction, heart failure, and sudden cardiac death ...
Left ventricular systolic/diastolic function evaluated by quantitative
Left ventricular systolic/diastolic function evaluated by quantitative

... because this method is still widely used, although the analysis by two- (2D) or three-dimensional (3D) echocardiography has recently been tried.17 The 1D UCG analysis may cause some error in cases including the distortion of the shape of the LV with right ventricular dilatation or aneurysm formation ...
Endocardial mapping of atrial fibrillation in the human right atrium
Endocardial mapping of atrial fibrillation in the human right atrium

... Our definitions differed from that of Konings et al. in that data were acquired from the entire right atrium and we stipulated that a set number of wave fronts should be present for >50% of the time period analysed, rather than for the entire period. Thus, in this study, larger areas of the right atr ...
Distribution of late gadolinium enhancement in various types of
Distribution of late gadolinium enhancement in various types of

... different views in a patient with DCM. In LGE-CMR, DCM has been shown to demonstrate mostly a lack of LGE or the presence of mid-wall enhancement, and a fewer part of cases shows patchy or diffuse striated LGE. The distribution of LGE is unrelated to a particular coronary arterial territory, and cor ...
Failure of Glycogen Depletion to Improve Left Ventricular Function of
Failure of Glycogen Depletion to Improve Left Ventricular Function of

... Grotyohann, we found that none of the methods showed an improvement in ventricular performance in hearts rendered ischemic and then reperfused. We were also unable to correlate functional recovery with lactate levels during ischemia. Instead, we found that hearts depleted of glycogen prior to ischem ...
PI LANOXIN (Digoxin) [PI] - Aspen Pharmacare Australia
PI LANOXIN (Digoxin) [PI] - Aspen Pharmacare Australia

... reduced sympathetic tone and diminished impulse conduction rate through the atria and atrioventricular node. Thus a major beneficial effect of digoxin is reduction in ventricular rate. Digoxin prolongs the effective refractory period • Digoxin decreases plasma renin activity and serum aldosterone le ...
Pediatric Pads - The Loudoun County Volunteer Rescue Squad
Pediatric Pads - The Loudoun County Volunteer Rescue Squad

... Teamwork* Integrity* 11 Professionalism* Service* ...
R P V C
R P V C

... Even though valve-sparing procedures are being used more frequently in the last few years18-20, long-term outcomes with this procedure are far to be known. Regardless, the number of patients with repaired TOF requiring intervention due to pulmonary valve regurgitation remains high nowadays. These ar ...
Inhibition of histone deacetylase on ventricular remodeling in
Inhibition of histone deacetylase on ventricular remodeling in

... Daily administration of VPA or tributyrin for a given period was well tolerated, because it did not affect overall body weight compared with vehicle (Table 1). No differences in mortality between vehicle and treated groups were found throughout the study. No sham-operated rats showed evidence of car ...
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Ventricular fibrillation



Ventricular fibrillation (V-fib or VF) is a condition in which there is uncoordinated contraction of the cardiac muscle of the ventricles in the heart, making them quiver rather than contract properly. Ventricular fibrillation is the most commonly identified arrhythmia in cardiac arrest patients. While there is some activity, the lay person is usually unable to detect it by palpating (feeling) the major pulse points of the carotid and femoral arteries. Such an arrhythmia is only confirmed by electrocardiography. Ventricular fibrillation is a medical emergency that requires prompt Advanced Life Support interventions. If this arrhythmia continues for more than a few seconds, it will likely degenerate further into asystole (""flatline""). This condition results in cardiogenic shock and cessation of effective blood circulation. As a consequence, sudden cardiac death (SCD) will result in a matter of minutes. If the patient is not revived after a sufficient period (within roughly 5 minutes at room temperature), the patient could sustain irreversible brain damage and possibly become brain-dead, due to the effects of cerebral hypoxia. On the other hand, death often occurs if sinus rhythm is not restored within 90 seconds of the onset of VF, especially if it has degenerated further into asystole.
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