ACC/AHA/ESC 2006 Guidelines for Management of Patients With
... AE, Chaitman B, Fromer M, Gregoratos G, Klein G, Moss AJ, Myerburg RJ, Priori SG, Quinones MA, Roden DM, Silka MJ, Tracy C. ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology/ ...
... AE, Chaitman B, Fromer M, Gregoratos G, Klein G, Moss AJ, Myerburg RJ, Priori SG, Quinones MA, Roden DM, Silka MJ, Tracy C. ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology/ ...
ACC/AHA/ESC 2006 Guidelines for Management of
... AE, Chaitman B, Fromer M, Gregoratos G, Klein G, Moss AJ, Myerburg RJ, Priori SG, Quinones MA, Roden DM, Silka MJ, Tracy C. ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology/ ...
... AE, Chaitman B, Fromer M, Gregoratos G, Klein G, Moss AJ, Myerburg RJ, Priori SG, Quinones MA, Roden DM, Silka MJ, Tracy C. ACC/AHA/ESC 2006 guidelines for management of patients with ventricular arrhythmias and the prevention of sudden cardiac death: a report of the American College of Cardiology/ ...
Conduction Defects
... It remains uncertain whether local delay (or block) of the atrial activation can result in notching of the P-wave without an increase in its duration. On the other hand, some normal subjects, with no evidence of heart disease, do have a small notch at the peak of the P-wave, which is probably relate ...
... It remains uncertain whether local delay (or block) of the atrial activation can result in notching of the P-wave without an increase in its duration. On the other hand, some normal subjects, with no evidence of heart disease, do have a small notch at the peak of the P-wave, which is probably relate ...
Differences in Sarcoplasmic Reticulum Ca2+ Leak Characteristics
... colleagues (26) have been the primary proponents of the idea that SR Ca2+ leak may be increased by RyR2 hyperphosphorylation for 10 years. They showed that phosphorylation by either protein PKA or CaMKII might increase RyR2 phosphorylation status and activity (26, 41, 42). RyR2 hyperphosphorylation ...
... colleagues (26) have been the primary proponents of the idea that SR Ca2+ leak may be increased by RyR2 hyperphosphorylation for 10 years. They showed that phosphorylation by either protein PKA or CaMKII might increase RyR2 phosphorylation status and activity (26, 41, 42). RyR2 hyperphosphorylation ...
PDF - Heart Rhythm Society
... is to improve patient care and health outcomes in a costeffective manner, but it is not intended to ignore uncertainty and nuance intrinsic to clinical decision making. Therefore, AUC should not be considered substitutes for sound clinical judgment and practice experience. The AUC process itself is ...
... is to improve patient care and health outcomes in a costeffective manner, but it is not intended to ignore uncertainty and nuance intrinsic to clinical decision making. Therefore, AUC should not be considered substitutes for sound clinical judgment and practice experience. The AUC process itself is ...
Three-dimensional transmural organization of perimysial collagen in
... (27). This laminar model of the ventricular myocardium views cardiac myocytes as being organized in branching layers surrounded by an extensive perimysial collagen network. The 3-D arrangement of myocardial laminae accommodates the changing fiber orientation across the ventricular wall, and the regu ...
... (27). This laminar model of the ventricular myocardium views cardiac myocytes as being organized in branching layers surrounded by an extensive perimysial collagen network. The 3-D arrangement of myocardial laminae accommodates the changing fiber orientation across the ventricular wall, and the regu ...
Electrocardiogram Interpretation
... cardiologists in difficult or uncertain cases, but such consultation takes time to set up, and is disruptive for both physicians. For all these reasons, rural family physicians must have good ECG interpretation skills. There is little literature on the use of ECG’s in urban or rural family practice. ...
... cardiologists in difficult or uncertain cases, but such consultation takes time to set up, and is disruptive for both physicians. For all these reasons, rural family physicians must have good ECG interpretation skills. There is little literature on the use of ECG’s in urban or rural family practice. ...
TBX5 drives Scn5a expression to regulate cardiac conduction
... demonstrated immediate recovery of normal cardiac function after episodes of spontaneous ventricular tachycardia (Figure 3C). Together, these data indicate that the conduction defects observed in Tbx5minKCreERT2 mice did not derive from a secondary consequence of myocardial dysfunction. Tbx5 is not ...
... demonstrated immediate recovery of normal cardiac function after episodes of spontaneous ventricular tachycardia (Figure 3C). Together, these data indicate that the conduction defects observed in Tbx5minKCreERT2 mice did not derive from a secondary consequence of myocardial dysfunction. Tbx5 is not ...
Systematic Review: Comparative Effectiveness of Radiofrequency
... The following 3 key questions were formulated: 1. What is the effect of radiofrequency catheter ablation on short-term (6 to 12 months) and long-term (⬎12 months) rhythm control; rates of congestive heart failure; changes in the size of the left atrium and ventricle; rates of stroke; quality of life ...
... The following 3 key questions were formulated: 1. What is the effect of radiofrequency catheter ablation on short-term (6 to 12 months) and long-term (⬎12 months) rhythm control; rates of congestive heart failure; changes in the size of the left atrium and ventricle; rates of stroke; quality of life ...
the left atrium in hypertension: a symbol of mortality and morbidity?
... recurrence of atrial fibrillation following successful electrical cardioversion to sinus rhythm [8]. The echocardiographic determination of left atrial size both by M-mode and two-dimensional methods have demonstrated a good correlation with cineangiographic measurements [9]. What could account for ...
... recurrence of atrial fibrillation following successful electrical cardioversion to sinus rhythm [8]. The echocardiographic determination of left atrial size both by M-mode and two-dimensional methods have demonstrated a good correlation with cineangiographic measurements [9]. What could account for ...
Myocardial Extracellular Volume Fraction From T1 Measurements in
... myocardial reference region may be inappropriately identified. Furthermore, the optimal threshold for quantifying LGE in the presence of diffuse or patchy fibrosis is not well defined (8). These limitations have prompted research into novel CMR-based quantitative techniques for measurement of the myoca ...
... myocardial reference region may be inappropriately identified. Furthermore, the optimal threshold for quantifying LGE in the presence of diffuse or patchy fibrosis is not well defined (8). These limitations have prompted research into novel CMR-based quantitative techniques for measurement of the myoca ...
atrial fibrillation
... the characteristic electrocardiographic changes of atrial fibrillation. Atrial fibrillation involves an absence of P waves and an irregularly, irregular ventricular rate. These cardiac abnormalities also cause loss of atrial systole and several other changes in cardiac performance that will be disc ...
... the characteristic electrocardiographic changes of atrial fibrillation. Atrial fibrillation involves an absence of P waves and an irregularly, irregular ventricular rate. These cardiac abnormalities also cause loss of atrial systole and several other changes in cardiac performance that will be disc ...
The Effects of /3-Adrenergic Stimulation on the
... baseline values (P=.01). Sematilide and sematilide/isoproterenol had no effect on ventricular conduction. Amiodarone increased the QRS duration by 14±4% (paced cycle length, 500 ms) to 32±5o% (paced cycle length, 300 ms) compared with baseline values. Isoproterenol attenuated amiodarone-induced QRS ...
... baseline values (P=.01). Sematilide and sematilide/isoproterenol had no effect on ventricular conduction. Amiodarone increased the QRS duration by 14±4% (paced cycle length, 500 ms) to 32±5o% (paced cycle length, 300 ms) compared with baseline values. Isoproterenol attenuated amiodarone-induced QRS ...
toward consistent definitions for preload and afterload
... stress” in both definitions helps the student appreciate both the complexities of cardiac pathophysiology and the rationale for therapeutic intervention. ...
... stress” in both definitions helps the student appreciate both the complexities of cardiac pathophysiology and the rationale for therapeutic intervention. ...
Interatrial septal thickness as a marker of structural and functional
... fibrosis, and to predict functional remodeling of LA and recurrence rate after AF ablation [7,9]. However, DE-MRI is not routinely available outside of research facilities. Therefore, more widely available and more reproducible noninvasive imaging techniques should be investigated for use in clinica ...
... fibrosis, and to predict functional remodeling of LA and recurrence rate after AF ablation [7,9]. However, DE-MRI is not routinely available outside of research facilities. Therefore, more widely available and more reproducible noninvasive imaging techniques should be investigated for use in clinica ...
Time-dependent remodeling of transmural architecture underlying
... (LVEDP) (20), and eccentric hypertrophy, due to a proportional increase in myocyte length and diameter (10, 11, 17, 18, 22), and the increase in myofiber cross-sectional area accounts for 50% of the ventricular volume increase (6). The remodeling of the extracellular matrix in this model is characte ...
... (LVEDP) (20), and eccentric hypertrophy, due to a proportional increase in myocyte length and diameter (10, 11, 17, 18, 22), and the increase in myofiber cross-sectional area accounts for 50% of the ventricular volume increase (6). The remodeling of the extracellular matrix in this model is characte ...
Acute myocardial infarction: pre-hospital and in
... initiate thrombolysis within 90 min of the patient calling for medical treatment (‘call to needle’ time). In patients with slowly evolving, or stuttering myocardial infarction, a series of ECGs and clinical assessments should be performed to detect evolving infarction (with rapid cardiac enzyme anal ...
... initiate thrombolysis within 90 min of the patient calling for medical treatment (‘call to needle’ time). In patients with slowly evolving, or stuttering myocardial infarction, a series of ECGs and clinical assessments should be performed to detect evolving infarction (with rapid cardiac enzyme anal ...
Three-dimensional residual strain in midanterior canine left ventricle
... a is the fiber angle from the (1–2) plane. Each of the two cleavage plane measurements (b8 and b9) was used to calculate the sheet angle b from the appropriate equation (1a or 1b), with a interpolated at the corresponding relative wall depth from linear least-squares fits to the measured fiber angle ...
... a is the fiber angle from the (1–2) plane. Each of the two cleavage plane measurements (b8 and b9) was used to calculate the sheet angle b from the appropriate equation (1a or 1b), with a interpolated at the corresponding relative wall depth from linear least-squares fits to the measured fiber angle ...
Perioperative Assessment of Diastolic Dysfunction
... It is now established that 50% of patients with congestive heart failure (CHF) have normal systolic function,6,7 and the same percentage of patients undergoing cardiac or noncardiac procedures have echocardiographically demonstrable diastolic function abnormalities.8 This may be important, because t ...
... It is now established that 50% of patients with congestive heart failure (CHF) have normal systolic function,6,7 and the same percentage of patients undergoing cardiac or noncardiac procedures have echocardiographically demonstrable diastolic function abnormalities.8 This may be important, because t ...
2012 EHRA/HRS expert consensus statement on cardiac
... LVEF ⬍ 40%. Aldosterone antagonists and nitrate-hydralazine combinations are indicated for selected patient populations although future guidelines are likely to expand indications for aldosterone antagonists.6 Treatment algorithms have been proposed for patients with symptomatic heart failure and re ...
... LVEF ⬍ 40%. Aldosterone antagonists and nitrate-hydralazine combinations are indicated for selected patient populations although future guidelines are likely to expand indications for aldosterone antagonists.6 Treatment algorithms have been proposed for patients with symptomatic heart failure and re ...
REGULATION OF CARDIAC VOLTAGE GATED POTASSIUM
... morbidity worldwide. CVD accounts for more deaths than all forms of cancer in the United States. Hypertension, Heart Failure and Atrial Fibrillation are the most common diagnosis, hospitalization cause and the sustained cardiac arrhythmia respectively in the US. Sudden cardiac death is the one of th ...
... morbidity worldwide. CVD accounts for more deaths than all forms of cancer in the United States. Hypertension, Heart Failure and Atrial Fibrillation are the most common diagnosis, hospitalization cause and the sustained cardiac arrhythmia respectively in the US. Sudden cardiac death is the one of th ...
Scar Extension Measured by Magnetic Resonance–Based Signal
... VT was targeted if it was mappable or its morphology was similar to the spontaneous or previously induced VT, even if the cycle length was significantly shorter. ...
... VT was targeted if it was mappable or its morphology was similar to the spontaneous or previously induced VT, even if the cycle length was significantly shorter. ...
Modification of ventricular repolarization in silent long QT
... tachycardia, torsade de pointes, and sudden cardiac death. The most common subtypes, LQT1 and LQT2, are caused by loss-of-function mutations in slow (IKs) and fast (IKr) cardiac potassium channels, whereas subtype LQT3 is caused by gain-of-function mutations in cardiac sodium channel (INa). The diso ...
... tachycardia, torsade de pointes, and sudden cardiac death. The most common subtypes, LQT1 and LQT2, are caused by loss-of-function mutations in slow (IKs) and fast (IKr) cardiac potassium channels, whereas subtype LQT3 is caused by gain-of-function mutations in cardiac sodium channel (INa). The diso ...
Academic paper: Left atrial appendage closure: An emerging option
... embolism, and 5 with pericardial effusions. Urena et al33 reported similar results in 52 patients with absolute contraindications to warfarin, with a 98.1% implantation rate. Patients were then maintained on either single or dual antiplatelet therapy at the discretion of the operator. At 20-month fo ...
... embolism, and 5 with pericardial effusions. Urena et al33 reported similar results in 52 patients with absolute contraindications to warfarin, with a 98.1% implantation rate. Patients were then maintained on either single or dual antiplatelet therapy at the discretion of the operator. At 20-month fo ...
Slide Set - Professional Heart Daily
... Only consensus of experts opinion, case studies, or standard of care Very limited populations evaluated ...
... Only consensus of experts opinion, case studies, or standard of care Very limited populations evaluated ...
Ventricular fibrillation
Ventricular fibrillation (V-fib or VF) is a condition in which there is uncoordinated contraction of the cardiac muscle of the ventricles in the heart, making them quiver rather than contract properly. Ventricular fibrillation is the most commonly identified arrhythmia in cardiac arrest patients. While there is some activity, the lay person is usually unable to detect it by palpating (feeling) the major pulse points of the carotid and femoral arteries. Such an arrhythmia is only confirmed by electrocardiography. Ventricular fibrillation is a medical emergency that requires prompt Advanced Life Support interventions. If this arrhythmia continues for more than a few seconds, it will likely degenerate further into asystole (""flatline""). This condition results in cardiogenic shock and cessation of effective blood circulation. As a consequence, sudden cardiac death (SCD) will result in a matter of minutes. If the patient is not revived after a sufficient period (within roughly 5 minutes at room temperature), the patient could sustain irreversible brain damage and possibly become brain-dead, due to the effects of cerebral hypoxia. On the other hand, death often occurs if sinus rhythm is not restored within 90 seconds of the onset of VF, especially if it has degenerated further into asystole.