Reduced Systolic Torsion in Chronic “Pure” Mitral Regurgitation
... CIMR, sorting out the impact of MR from that of ischemia on ventricular function may have important clinical consequences. For example, the surgical treatment options for patients with CIMR include coronary artery bypass grafting (CABG) or mitral valve annuloplasty or replacement. Currently, the mos ...
... CIMR, sorting out the impact of MR from that of ischemia on ventricular function may have important clinical consequences. For example, the surgical treatment options for patients with CIMR include coronary artery bypass grafting (CABG) or mitral valve annuloplasty or replacement. Currently, the mos ...
Understanding diastolic heart failure
... Many patients who present with symptoms of heart failure are found to have a normal left ventricular ejection fraction and therefore were labelled as having “diastolic heart failure” implying that the underlying pathophysiology is due to diastolic dysfunction alone. However, using a combination of e ...
... Many patients who present with symptoms of heart failure are found to have a normal left ventricular ejection fraction and therefore were labelled as having “diastolic heart failure” implying that the underlying pathophysiology is due to diastolic dysfunction alone. However, using a combination of e ...
Overexpression of a human potassium channel suppresses cardiac
... noninfected and AdGFP-infected cells show predominately the level of sustained Ito1 current primarily at potentials beyond 0 mV. In AdHERG-infected cells, activation of HERG current begins at –10 mV and then dominates the I-V relationship at positive voltages. The magnitude of sustained current is l ...
... noninfected and AdGFP-infected cells show predominately the level of sustained Ito1 current primarily at potentials beyond 0 mV. In AdHERG-infected cells, activation of HERG current begins at –10 mV and then dominates the I-V relationship at positive voltages. The magnitude of sustained current is l ...
Modelling of the ventricular conduction system
... Nowadays an important area in the study of cardiac arrhythmias is anatomically accurate modelling. The majority of current anatomical models have not included a description of the Purkinje network. As a consequence, these models cannot be used to study the important role of the Purkinje system in ar ...
... Nowadays an important area in the study of cardiac arrhythmias is anatomically accurate modelling. The majority of current anatomical models have not included a description of the Purkinje network. As a consequence, these models cannot be used to study the important role of the Purkinje system in ar ...
animal models / simulations / manikin studies
... influence of using the Esmarch manoeuvre (bimanual jaw-thrust), a nasopharyngeal airway, an oropharyngeal airway, or the Jaw-Thrust-Device on airway physiology in 50 healthy adults with body mass index < 35 kg/m2, undergoing standard facemask ventilation for routine induction of anaesthesia. The ma ...
... influence of using the Esmarch manoeuvre (bimanual jaw-thrust), a nasopharyngeal airway, an oropharyngeal airway, or the Jaw-Thrust-Device on airway physiology in 50 healthy adults with body mass index < 35 kg/m2, undergoing standard facemask ventilation for routine induction of anaesthesia. The ma ...
Impaired right and left ventricular diastolic
... and dyssynchronous ventricular relaxation.3 – 6 However, assessment of RV diastolic dysfunction is difficult using Doppler flow parameters.7 Consequently, RV and LV diastolic dysfunction, and diastolic dyssynchrony have not been well characterized in TOF patients beyond the phenomenon of restrictive ...
... and dyssynchronous ventricular relaxation.3 – 6 However, assessment of RV diastolic dysfunction is difficult using Doppler flow parameters.7 Consequently, RV and LV diastolic dysfunction, and diastolic dyssynchrony have not been well characterized in TOF patients beyond the phenomenon of restrictive ...
National Medical Policy
... (TDE) and real-time three-dimensional echocardiography (RT3DE) could be used for evaluation of the RV performance. The purpose of this study was to assess RV function in patients with inferior wall acute MI with both TDE and RT3DE. The study included 85 patients in the acute phase of MI complicated ...
... (TDE) and real-time three-dimensional echocardiography (RT3DE) could be used for evaluation of the RV performance. The purpose of this study was to assess RV function in patients with inferior wall acute MI with both TDE and RT3DE. The study included 85 patients in the acute phase of MI complicated ...
Thesis, Emmanuel Moss 20110625 Final
... throughout in 2 canines. Surface area of REPOL∆ diminished with successive denervation, from 365±252 at baseline to 53±106mm2 following RAGP ablation (p<0.03). With retrograde denervation, chronotropic and repolarisation changes were suppressed following RAGP ablation in two canines, and following A ...
... throughout in 2 canines. Surface area of REPOL∆ diminished with successive denervation, from 365±252 at baseline to 53±106mm2 following RAGP ablation (p<0.03). With retrograde denervation, chronotropic and repolarisation changes were suppressed following RAGP ablation in two canines, and following A ...
The ECGs that will be read around the world—and save lives of
... ▸ Except: QRS voltage criteria for LVH occurring with any non-voltage criteria for LVH such as left atrial enlargement, left axis deviation, ST segment depression, T-wave inversion or pathological Q waves 9. Early repolarisation (ST elevation, J-point elevation, J-waves or terminal QRS slurring) 10. ...
... ▸ Except: QRS voltage criteria for LVH occurring with any non-voltage criteria for LVH such as left atrial enlargement, left axis deviation, ST segment depression, T-wave inversion or pathological Q waves 9. Early repolarisation (ST elevation, J-point elevation, J-waves or terminal QRS slurring) 10. ...
Strain and Strain Rate Imaging by Echocardiography
... Abbbssstttrrraaacccttt::: Echocardiographic strain and strain-rate imaging (deformation imaging) is a new non-invasive method for assessment of myocardial function. Due to its ability to differentiate between active and passive movement of myocardial segments, to quantify intraventricular dyssynchro ...
... Abbbssstttrrraaacccttt::: Echocardiographic strain and strain-rate imaging (deformation imaging) is a new non-invasive method for assessment of myocardial function. Due to its ability to differentiate between active and passive movement of myocardial segments, to quantify intraventricular dyssynchro ...
dbl dobutamine hydrochloride injection
... contractility, there were electrocardiographic signs of increased ischaemia. Recent studies in animals suggest that functional deterioration and possible enlargement of experimental myocardial lesions during the administration of inotropic medicines including dobutamine hydrochloride is related to t ...
... contractility, there were electrocardiographic signs of increased ischaemia. Recent studies in animals suggest that functional deterioration and possible enlargement of experimental myocardial lesions during the administration of inotropic medicines including dobutamine hydrochloride is related to t ...
ACCF/HRS/AHA/ASE/HFSA/SCAI/SCCT/SCMR 2013 Appropriate
... Jessup M, Kapa S, Kremers MS, Lindsay BD, Stevenson LW. ACCF/HRS/AHA/ ASE/HFSA/SCAI/SCCT/SCMR 2013 appropriate use criteria for implantable cardioverter-defibrillators and cardiac resynchronization therapy: a report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force ...
... Jessup M, Kapa S, Kremers MS, Lindsay BD, Stevenson LW. ACCF/HRS/AHA/ ASE/HFSA/SCAI/SCCT/SCMR 2013 appropriate use criteria for implantable cardioverter-defibrillators and cardiac resynchronization therapy: a report of the American College of Cardiology Foundation Appropriate Use Criteria Task Force ...
Should All Patients With Heart Block Receive Biventricular Pacing?
... and normal LVEF. Moreover, the potential mechanism of the benefit of biventricular pacing appeared to be related to the correction of systolic dyssynchrony. Despite these encouraging studies, the evidence is not yet sufficiently strong to support widespread adoption of biventricular pacing in patien ...
... and normal LVEF. Moreover, the potential mechanism of the benefit of biventricular pacing appeared to be related to the correction of systolic dyssynchrony. Despite these encouraging studies, the evidence is not yet sufficiently strong to support widespread adoption of biventricular pacing in patien ...
Case Report: Left bundle branch block: a rare ECG - SVIMS
... confirmity of ECG manifestations with serum postassium levels and this disparity was attributed to the presence of ECG alterations from o ther causes or to conco mitant abnormalities of other electro lytes. 8 In nephrectomized animals or in the presence of renal disease with acidosis, small increase ...
... confirmity of ECG manifestations with serum postassium levels and this disparity was attributed to the presence of ECG alterations from o ther causes or to conco mitant abnormalities of other electro lytes. 8 In nephrectomized animals or in the presence of renal disease with acidosis, small increase ...
Mechanisms underlying delayed afterdepolarizations in - AJP
... from a nonselective cation channel and from a Cl⫺ channel. The latter is expressed only in hypertrophied myocytes. In hypertrophy, the density of caffeine-induced Na/Ca exchange current (INa/Ca) was increased by 26%, sarcoplasmic reticulum (SR) Ca2⫹ content as assessed from the integral of INa/Ca wa ...
... from a nonselective cation channel and from a Cl⫺ channel. The latter is expressed only in hypertrophied myocytes. In hypertrophy, the density of caffeine-induced Na/Ca exchange current (INa/Ca) was increased by 26%, sarcoplasmic reticulum (SR) Ca2⫹ content as assessed from the integral of INa/Ca wa ...
Widening Indications of Pacemakers - The Association of Physicians
... properties, such as beta blockers and amiodarone, are commonly used in this population. In addition, the incidence of bundle branch block and intraventricular conduction delays is high in the presence of dilated cardiomyopathy. Therefore, permanent pacing is frequently indicated in subjects with con ...
... properties, such as beta blockers and amiodarone, are commonly used in this population. In addition, the incidence of bundle branch block and intraventricular conduction delays is high in the presence of dilated cardiomyopathy. Therefore, permanent pacing is frequently indicated in subjects with con ...
Brugada Syndrome - Department of Medicine | Columbia University
... Fig 3. Examples of 2 different mutations in SCN5A leading to a loss of function of the sodium (Na) channel. A, Mutation I1660V, producing a trafficking defect of the Na channel, and thus a decrease of Na channels present in the sarcolemma. Mutant and WT Na channels have been expressed in TSA201 cell ...
... Fig 3. Examples of 2 different mutations in SCN5A leading to a loss of function of the sodium (Na) channel. A, Mutation I1660V, producing a trafficking defect of the Na channel, and thus a decrease of Na channels present in the sarcolemma. Mutant and WT Na channels have been expressed in TSA201 cell ...
Pacing System Malfunction: Evaluation and Troubleshooting
... should be identified. An examination of anchoring sleeve for adequate fixation, looking for adequate amount of current-of-injury in the recorded electrograms at the implant time, and looking for proper lead slack on postimplant chest x-ray would be highly informative. In most cases, lead repositioni ...
... should be identified. An examination of anchoring sleeve for adequate fixation, looking for adequate amount of current-of-injury in the recorded electrograms at the implant time, and looking for proper lead slack on postimplant chest x-ray would be highly informative. In most cases, lead repositioni ...
Antiarrhythmic Drugs Munir Gharaibeh MD, PhD, MHPE Faculty of
... Delayed Afterdepolarizations (DAD): – Occur with increased intracellular calcium. – Exacerbated by fast heart rates. – Responsible for arrhythmias of digitalis, catecholamines, and ischemia. ...
... Delayed Afterdepolarizations (DAD): – Occur with increased intracellular calcium. – Exacerbated by fast heart rates. – Responsible for arrhythmias of digitalis, catecholamines, and ischemia. ...
CardioNet, Inc. v. MedNet Healthcare
... receive arrhythmia information from the monitoring system and configured to receive humanassessed arrhythmia information from the monitoring station wherein the human-assessed arrhythmia information derives from at least a portion of the physiological data and wherein the processing system is capabl ...
... receive arrhythmia information from the monitoring system and configured to receive humanassessed arrhythmia information from the monitoring station wherein the human-assessed arrhythmia information derives from at least a portion of the physiological data and wherein the processing system is capabl ...
cardiovascular magnetic resonance in the prediction of outcome
... presence of either CMR-TSI >110ms or PL scar resulted in a worse outcome, whilst the presence of both was associated with the highest mortality. A final study in 148 patients allowed the development of a risk score to predict mortality from CRT on the basis of 16 candidate variables. PL scar, dyssyn ...
... presence of either CMR-TSI >110ms or PL scar resulted in a worse outcome, whilst the presence of both was associated with the highest mortality. A final study in 148 patients allowed the development of a risk score to predict mortality from CRT on the basis of 16 candidate variables. PL scar, dyssyn ...
Quantification of Left Ventricular Function With Premature
... ECGs recorded in a magnetic field are distorted by the magnetohemodynamic effect, which limits the interpretability of the 3-lead ECG when compared with a 12-lead ECG outside of the magnet.10 However, because of the need for ECG gating in cine CMR, robust 3-lead (ECG) acquisition, filtering, and rea ...
... ECGs recorded in a magnetic field are distorted by the magnetohemodynamic effect, which limits the interpretability of the 3-lead ECG when compared with a 12-lead ECG outside of the magnet.10 However, because of the need for ECG gating in cine CMR, robust 3-lead (ECG) acquisition, filtering, and rea ...
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... People with atrial fibrillation may be asymptomatic or experience symptoms such as palpitations, dizziness, breathlessness and fatigue (NHS Choices 2015). Atrial fibrillation can be classified as paroxysmal (an intermittent episode of atrial fibrillation which spontaneously terminates within 7 days, ...
... People with atrial fibrillation may be asymptomatic or experience symptoms such as palpitations, dizziness, breathlessness and fatigue (NHS Choices 2015). Atrial fibrillation can be classified as paroxysmal (an intermittent episode of atrial fibrillation which spontaneously terminates within 7 days, ...
Vagal nerve stimulation activates vagal afferent fibers - AJP
... The electrophysiological effects of stimulation of the intact right and left vagosympathetic trunk appear to be similar in a porcine model, without significant global or regional differences (52). Although the vagosympathetic trunk provides important cardiomotor efferent fibers to the heart, ⬎80% of ...
... The electrophysiological effects of stimulation of the intact right and left vagosympathetic trunk appear to be similar in a porcine model, without significant global or regional differences (52). Although the vagosympathetic trunk provides important cardiomotor efferent fibers to the heart, ⬎80% of ...
Better Lesion Creation And Assessment During Catheter
... for other macro-reentrant atrial arrhythmias and as the substrate for some macroreentrant atrial tachycardias after circumferential antral PVI.28,29,31,34,35 In a histopathologic study in patients undergoing MAZE for recurrent AF after initially successful catheter ablation for AF, Kowalski et al pe ...
... for other macro-reentrant atrial arrhythmias and as the substrate for some macroreentrant atrial tachycardias after circumferential antral PVI.28,29,31,34,35 In a histopathologic study in patients undergoing MAZE for recurrent AF after initially successful catheter ablation for AF, Kowalski et al pe ...
Ventricular fibrillation
Ventricular fibrillation (V-fib or VF) is a condition in which there is uncoordinated contraction of the cardiac muscle of the ventricles in the heart, making them quiver rather than contract properly. Ventricular fibrillation is the most commonly identified arrhythmia in cardiac arrest patients. While there is some activity, the lay person is usually unable to detect it by palpating (feeling) the major pulse points of the carotid and femoral arteries. Such an arrhythmia is only confirmed by electrocardiography. Ventricular fibrillation is a medical emergency that requires prompt Advanced Life Support interventions. If this arrhythmia continues for more than a few seconds, it will likely degenerate further into asystole (""flatline""). This condition results in cardiogenic shock and cessation of effective blood circulation. As a consequence, sudden cardiac death (SCD) will result in a matter of minutes. If the patient is not revived after a sufficient period (within roughly 5 minutes at room temperature), the patient could sustain irreversible brain damage and possibly become brain-dead, due to the effects of cerebral hypoxia. On the other hand, death often occurs if sinus rhythm is not restored within 90 seconds of the onset of VF, especially if it has degenerated further into asystole.