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An American Heart Association Journal Volume 10 ◼ Number 2 February 2017 Editorials Cardiac Resynchronization Therapy Upgrade: Verschlimmbesserung? Anoop K. Shetty, MD; Christopher A. Rinaldi, MD · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · e004956 Ventricular Microanatomy, Arrhythmias, and the Electrochemical Driving Force for Na+: Is There a Need for Flipped Learning? Luiz Belardinelli, MD; Mary M. Maleckar, PhD; Wayne R. Giles, PhD · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · e004955 Selective Modulation of the Cardiac Autonomic Nervous System: A New Strategy for Treatment of Cardiohibitory Syncope Siva K. Mulpuru, MD; Win-Kuang Shen, MD · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · e004994 Downloaded from http://circep.ahajournals.org/ by guest on May 3, 2017 Original Articles Effect of Sleep-Disordered Breathing on Appropriate Implantable Cardioverter-Defibrillator Therapy in Patients With Heart Failure: A Systematic Review and Meta-Analysis Younghoon Kwon, MD, MS; Ryan J. Koene, MD; Osung Kwon, MD; Jessica V. Kealhofer, MD; Selcuk Adabag, MD, MS; Sue Duval, PhD · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · e004609 Effects of Upgrade Versus De Novo Cardiac Resynchronization Therapy on Clinical Response and Long-Term Survival: Results From a Multicenter Study Mate Vamos, MD; Julia W. Erath, MD; Zsolt Bari, MD; Denes Vagany, MD; Sven P. Linzbach, MD; Tatsiana Burmistrava, MD; Carsten W. Israel, MD; Gabor Z. Duray, MD, PhD; Stefan H. Hohnloser, MD · · · · · · · · e004471 Familial Occurrence of Atrioventricular Nodal Reentrant Tachycardia Yoav Michowitz, MD; Adi Anis-Heusler, MD; Eyal Reinstein, MD; Oholi Tovia-Brodie, MD; Aharon Glick, MD; Bernard Belhassen, MD · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · e004680 Association Between Posterior Left Atrial Adipose Tissue Mass and Atrial Fibrillation Alexander R. van Rosendael, MD; Aukelien C. Dimitriu-Leen, MD; Philippe J. van Rosendael, MD; Melissa Leung, MBBS, BSc(med), MBiostat, PhD; Jeff M. Smit, MD; Antti Saraste, MD, PhD; Juhani Knuuti, MD, PhD; Rob J. van der Geest, PhD; Britt W.H. van der Arend, BS; Erik W. van Zwet, PhD; Arthur J. Scholte, MD, PhD; Victoria Delgado, MD, PhD; Jeroen J. Bax, MD, PhD · · · · · · · · · · · · · · · · · · · e004614 Left Atrial Size and Function in Hypertrophic Cardiomyopathy Patients and Risk of New-Onset Atrial Fibrillation Philippe Debonnaire, MD, PhD; Emer Joyce, MB, BCh, BAO, PhD; Yasmine Hiemstra, MD; Bart J. Mertens, PhD; Douwe E. Atsma, MD, PhD; Martin J. Schalij, MD, PhD; Jeroen J. Bax, MD, PhD; Victoria Delgado, MD, PhD; Nina Ajmone Marsan, MD, PhD · · · · · · · · · · · · · · · · e004052 Revealing the Concealed Nature of Long-QT Type 3 Syndrome Amara Greer-Short, PhD; Sharon A. George, PhD; Steven Poelzing, PhD; Seth H. Weinberg, PhD · · · · · · · · e004400 Targets and End Points in Cardiac Autonomic Denervation Procedures Esteban W. Rivarola, MD, PhD; Denise Hachul, MD, PhD; Tan Wu, MD; Cristiano Pisani, MD; Carina Hardy, MD; Fabrizio Raimundi, BS; Sissy Melo, MD, PhD; Francisco Darrieux, MD, PhD; Mauricio Scanavacca, MD, PhD · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · e004638 Incidence of Idiopathic Ventricular Arrhythmias: A Population-Based Study Surksha Sirichand, MD; Ammar M. Killu, MBBS; Deepak Padmanabhan, MBBS; David O. Hodge, MS; Alanna M. Chamberlain, PhD; Peter A. Brady, MD; Suraj Kapa, MD; Peter A. Noseworthy, MD; Douglas L. Packer, MD; Thomas M. Munger, MD; Bernard J. Gersh, MB, ChB, DPhil; Christopher J. McLeod, MB, ChB, PhD; Win-Kuang Shen, MD; Yong-Mei Cha, MD; Samuel J. Asirvatham, MD; Paul A. Friedman, MD; Siva K. Mulpuru, MD · · · · · · · · · · · · · · · · · · · · · · · · · · · e004662 CIRCULATION: ARRHYTHMIA AND ELECTROPHYSIOLOGY (ISSN 1941-3084) is published monthly online-only by Wolters Kluwer Health, Inc. at 14700 Citicorp Drive, Bldg 3, Hagerstown, MD 21742. Business offices are located at Two Commerce Square, 2001 Market Street, Philadelphia, PA 19103. Production offices are located at 351 West Camden Street, Baltimore, MD 21201-2436. Individuals may subscribe for their personal use at the following annual rates world-wide: Members of any American Heart Association (AHA) scientific council will have online access to the journal as a benefit of membership. $322 for non-members. Additional rates can be found online at http://lww.com/circep. AHA membership information can be found online at professional.heart.org. Role of Apamin-Sensitive Calcium-Activated Small-Conductance Potassium Currents on the Mechanisms of Ventricular Fibrillation in Pacing-Induced Failing Rabbit Hearts Dechun Yin, MD; Yu-Cheng Hsieh, MD, PhD; Wei-Chung Tsai, MD; Adonis Zhi-Yang Wu, PhD; Zhaolei Jiang, MD; Yi-Hsin Chan, MD; Dongzhu Xu, MD, PhD; Na Yang, MD; Changyu Shen, PhD; Zhenhui Chen, PhD; Shien-Fong Lin, PhD; Peng-Sheng Chen, MD; Thomas H. Everett IV, PhD · · · · · · · · · · e004434 Improving the In Silico Assessment of Proarrhythmia Risk by Combining hERG (Human Ether-à-go-goRelated Gene) Channel–Drug Binding Kinetics and Multichannel Pharmacology Zhihua Li, PhD; Sara Dutta, PhD; Jiansong Sheng, PhD; Phu N. Tran, PhD; Wendy Wu, PhD; Kelly Chang, PhD; Thembi Mdluli, PhD; David G. Strauss, MD, PhD; Thomas Colatsky, PhD · · · · · · · · · · · e004628 Advances in Arrhythmia and Electrophysiology Adjunctive Interventional Techniques When Percutaneous Catheter Ablation for Drug Refractory Ventricular Arrhythmias Fail: A Contemporary Review Saurabh Kumar, BSc(Med), MBBS, PhD; Usha B. Tedrow, MD, MSc; William G. Stevenson, MD · · · · · · · · · e003676 Images and Case Reports in Arrhythmia and Electrophysiology Downloaded from http://circep.ahajournals.org/ by guest on May 3, 2017 Electrophysiological Twisting: Electrical Alternans in Congenital Dilated Cardiomyopathy Rimsha Arif, BSc; Arif Hussain, MD; Santokh Dhillon, MD · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · e004953 Correction to: Association of Rate-Dependent Conduction Block Between Eccentric Coronary Sinus to Left Atrial Connections with Inducible Atrial Fibrillation and Flutter· · · · · · · · · · · · · · · · · · · · · · · · · · · · · · · e000022 10 (2) Circ Arrhythm Electrophysiol. 2017;10: Downloaded from http://circep.ahajournals.org/ by guest on May 3, 2017 Circulation: Arrhythmia and Electrophysiology is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Copyright © 2017 American Heart Association, Inc. All rights reserved. Print ISSN: 1941-3149. Online ISSN: 1941-3084 The online version of this article, along with updated information and services, is located on the World Wide Web at: http://circep.ahajournals.org/content/10/2 Permissions: Requests for permissions to reproduce figures, tables, or portions of articles originally published in Circulation: Arrhythmia and Electrophysiology can be obtained via RightsLink, a service of the Copyright Clearance Center, not the Editorial Office. Once the online version of the published article for which permission is being requested is located, click Request Permissions in the middle column of the Web page under Services. Further information about this process is available in the Permissions and Rights Question and Answer document. Reprints: Information about reprints can be found online at: http://www.lww.com/reprints Subscriptions: Information about subscribing to Circulation: Arrhythmia and Electrophysiology is online at: http://circep.ahajournals.org//subscriptions/