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rate versus rhythm control in atrial fibrillation
rate versus rhythm control in atrial fibrillation

... attributable to the management of chronic AF to the individual is estimated at $8700, and to the nation, about $6 billion.1 AF is classified according to the time period of occurrence, as new–onset, paroxysmal (beginning and ending abruptly, usually lasting hours to less than 7 days), persistent (la ...
1443-ConsultationProtocol-Accessible
1443-ConsultationProtocol-Accessible

... cryptogenous stroke and infarcts of unknown, uncertain, or undetermined cause. Embolic stroke of undetermined source (ESUS) is also a related term which describes a subset of CS. What is the underlying mechanism of cryptogenic stroke? Why the underlying mechanism of CS is not determined could be due ...
Echocardiographic assessment of left ventricular diastolic function
Echocardiographic assessment of left ventricular diastolic function

... Mitral valve inflow in the assessment of diastolic function Mitral valve inflow assessed by pulsed wave Doppler remains the cornerstone of diastolic evaluation. Several parameters can be derived from mitral inflow velocities, which are useful for this evaluation. These include early diastolic transm ...
Sleep, dreams, and sudden death: the case for
Sleep, dreams, and sudden death: the case for

... are substantially blunted by beta-adrenergic receptor blockade [42]. A wide variety of supraventricular arrhythmias can also be induced by autonomic activation [23,43]. Experimentally, we have found that a striking surge in sympathetic activity occurs within minutes of left anterior descending coron ...
Catheter Ablation as a Treatment for Atrial Fibrillation
Catheter Ablation as a Treatment for Atrial Fibrillation

... radiofrequency ablation or cryoablation, is being studied in the treatment of various types of atrial fibrillation. Atrial fibrillation is the most common cardiac arrhythmia, with a prevalence estimated at 0.4% of the population, increasing with age. The underlying mechanism of atrial fibrillation i ...
Open and Thoracoscopic Approaches to Treat Atrial Fibrillation and
Open and Thoracoscopic Approaches to Treat Atrial Fibrillation and

... increased conduction time. Atrial flutter is a variant of atrial fibrillation. The first-line treatment for AF usually includes medications to maintain sinus rhythm and/or control the ventricular rate. Antiarrhythmic medications are only partially effective; therefore, medical treatment is not suffi ...
Transposition of a pericardial-derived vascular adipose flap for
Transposition of a pericardial-derived vascular adipose flap for

... data were analysed as repeated measures using ANOVA with the Greenhouse– Geisser correction. Values of P , 0.05 were considered significant. Microarray data analysis was performed using R and Bioconductor, with an RMA-normalization and non-specific filtering, and limma (linear models for microarray ...
Effects of prolonged anoxia on electrical activity of the heart in
Effects of prolonged anoxia on electrical activity of the heart in

... 1983). Under normoxic conditions these channels are kept closed by a high cytosolic energy charge, but reductions in the rate of ATP production reduces the ATP/ADP ratio, which triggers their opening (Flagg and Nichols, 2011). The outward K+ current (IKATP) reduces plateau duration of the cardiac A ...
The influence of residual coronary stenosis on size of
The influence of residual coronary stenosis on size of

... continued widespread use of this technique as a histochemical marker of tissue viability. Regarding the risk areas, we defined this area at the end of the study. Because of the possible changes in collateral flow, these may not have been the same as the risk areas before or immediately after circumf ...
Print - Circulation
Print - Circulation

... To evaluate the time course of decrease in left ventricular dilatation, a subset of 31 patients also underwent echocardiography at 10-14 days, as well as at 6-8 months and 3-7 years, after operation. All preoperative studies were performed while patients were taking no cardiac medications. Although ...
Bez nadpisu - Univerzita Karlova v Praze
Bez nadpisu - Univerzita Karlova v Praze

... Clinical Indications Diagnosis of coronary artery disease - presence - location (coronary territory) -extent (number of vascular territories ...
Paroxysmal atrial fibrillation in male endurance athletes. A 9
Paroxysmal atrial fibrillation in male endurance athletes. A 9

... work, and/or led to hospital admission for treatment of AF. The symptoms were classified ‘‘moderate’’ when AF could be tolerated, normal daily functioning could be continued but sporting activity during atrial fibrillation had to be interrupted. The symptoms were labelled ‘‘mild’’ when sporting acti ...
Document
Document

... family members of patients with confirmed ARVC/D) diagnosis of ARVC/D according to the 2010 TFC, who had an ECG recorded between February 1987 and March 2013 [7]. This baseline ECG was the first available ECG. Clinical information regarding demographics and symptoms were obtained from hospital recor ...
Document
Document

... uncommon in SVT ,with the exception of preexcited tachycardia .The specificity of concordant pattern for VT is >90% but sensitivity is low(20%).  Negative concordance in limb leads is another way of describing NW axis and suggests VT. ...
Dr Marcelo Abud case report
Dr Marcelo Abud case report

... sarcomeres, (causing ST segment elevation) and concomitantly producing more K+ output during phase 3 action potential by stimulating of slow delayed potasium channels (responsible for the sharp appearance of the T wave) This selective epicardial hipercontractility observed in males increases the cor ...
Soluble TNF Receptors Are Associated with Elevation Myocardial Infarction
Soluble TNF Receptors Are Associated with Elevation Myocardial Infarction

... Based on previous data, we calculated that a sample size of 21 subjects in each treatment group (42 subjects in total) would be sufficient to give 80% power to detect an estimated 20% change in plasma levels of the biomarkers [10]. Baseline and procedural variables are presented as mean with standar ...
European Heart Rhythm Association/Heart Failure Association joint
European Heart Rhythm Association/Heart Failure Association joint

... often co-exist, or may precipitate one another. Recent registry-based reports show that 40% of patients hospitalized for HF already have a history of AF, up to 50% of patients have AF at baseline, and nearly 20% of patients may experience new-onset AF during the hospitalization.5 In the EuroObserva ...
Cardiac Resynchronization for the Implanter
Cardiac Resynchronization for the Implanter

... electrode on the anterior RV to a ground and a second dipole from an active electrode on the posterolateral LV to a ground. ...
Physics of Cardiac Arrhythmogenesis
Physics of Cardiac Arrhythmogenesis

... studies of the giant squid axon conducted by Hodgkin and Huxley (HH), who also provided a mathematical framework to describe this propagation. Similar mechanisms govern electrical excitation in heart tissue, and extensions of the HH equations have been developed over the years to incorporate a growi ...
The endurance athletes heart: acute stress and chronic adaptation
The endurance athletes heart: acute stress and chronic adaptation

... Like cardiac morphology, there are some ECG patterns that have been reported in both the endurance athlete’s heart and cardiac pathologies and these can overlap in the ‘grey zone’. Common ECG findings in the endurance athlete’s heart, related to training, include sinus bradycardia, sinus arrhythmia, ...
Cardiac Remodeling in Response to 1 Year of Intensive - MET-TEST
Cardiac Remodeling in Response to 1 Year of Intensive - MET-TEST

... of endurance athletes are a result of exercise training or a genetically determined characteristic of talented athletes. We hypothesized that prolonged and intensive endurance training in previously sedentary healthy young individuals could induce cardiac remodeling similar to that observed cross-se ...
Why, where, and when do cardiac myocytes express - AJP
Why, where, and when do cardiac myocytes express - AJP

... excitation-contraction (EC) coupling is well known (3). With each beat, the propagating action potential depolarizes the sarcolemma of the excitable myocytes within the heart. Membrane depolarization leads to the activation of voltage-operated Ca2⫹ channels (VOCs), thereby causing a brief influx of ...
Carotid dP/dt as a Psychophysiological Index of Sympathetic
Carotid dP/dt as a Psychophysiological Index of Sympathetic

... Carlsten et al., 1957; Davies et al., 1951; Hoffman & Kaye et al. (1970) provides a more detailed elucidation of Suckling, 1953; Sarnoff & Mitchell, 1962). However, this effect. In that study Kaye et al. (1970) found that right more recent anatomical, contractile and histochemical vagal stimulation ...
Tei Index as a Method of Evaluating Left Ventricular Diastolic
Tei Index as a Method of Evaluating Left Ventricular Diastolic

... successful as far as the severity of LV diastolic dysfunction17 is concerned. In a recent study17 we found for the first time a “pseudonormalisation” of the LV index in a subgroup of patients with acute myocardial infarction (AMI) and diastolic dysfunction of restrictive physiology. Recently, Bruch ...
VENTRICULAR BRADYCARDIA I
VENTRICULAR BRADYCARDIA I

... other functions necessary to determine, select and deliver ...
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Ventricular fibrillation



Ventricular fibrillation (V-fib or VF) is a condition in which there is uncoordinated contraction of the cardiac muscle of the ventricles in the heart, making them quiver rather than contract properly. Ventricular fibrillation is the most commonly identified arrhythmia in cardiac arrest patients. While there is some activity, the lay person is usually unable to detect it by palpating (feeling) the major pulse points of the carotid and femoral arteries. Such an arrhythmia is only confirmed by electrocardiography. Ventricular fibrillation is a medical emergency that requires prompt Advanced Life Support interventions. If this arrhythmia continues for more than a few seconds, it will likely degenerate further into asystole (""flatline""). This condition results in cardiogenic shock and cessation of effective blood circulation. As a consequence, sudden cardiac death (SCD) will result in a matter of minutes. If the patient is not revived after a sufficient period (within roughly 5 minutes at room temperature), the patient could sustain irreversible brain damage and possibly become brain-dead, due to the effects of cerebral hypoxia. On the other hand, death often occurs if sinus rhythm is not restored within 90 seconds of the onset of VF, especially if it has degenerated further into asystole.
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