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Brain Computer Interface - Department of Electrical, Computer and
Brain Computer Interface - Department of Electrical, Computer and

...  Trained severely paralyzed people to self-regulate the slow cortical potentials in their EEG in such a way that these signals could be used as a binary signal to control a computer cursor (1990s)  Tests included writing characters with the cursor  System users require training just as any person ...
Biopsychology 2012 – sec 002
Biopsychology 2012 – sec 002

... 2. Neurotransmitters bind to post-synaptic receptors; 3. Binding of neurotransmitters opens ion channels, which produce: - EPSP: excitatory post-synaptic potentials (sodium goes in – makes action potential more likely to be produced), or - IPSP: inhibitory post-synaptic potentials (potassium goes ou ...
Lecture 5
Lecture 5

... beating (outside of CNS) • Slow wave sleep (1Hz) • Tremor, such as essential tremor or Parkinsonian tremor • Epilepsy: seizures are transient hypersynchronous neuronal activity in the Generalized 3 Hz spike and wave brain discharges reflecting seizure activity ...
Cholinergic induction of network oscillations at 40 Hz in the
Cholinergic induction of network oscillations at 40 Hz in the

... in the CA1 area7, cholinergically induced oscillations require ionotropic non-NMDA glutamate receptors. In both CA3 and CA1 the oscillatory activity was completely abolished by the non-NMDA glutamate receptor antagonist 6-nitro-7-sulphamoylbenzo(f)quinoxaline-2,3-dione (NBQX, 20 mM; n ¼ 5; Fig. 2c, ...
Buzsaki and Draguhn (2004), Neuronal Oscillations in Cortical
Buzsaki and Draguhn (2004), Neuronal Oscillations in Cortical

... of self-organized oscillatory networks of sleep to be turned ultimately into longterm memory by means of functional and structural synFig. 3. Representation by oscillation phase. (A) EEG theta aptic modifications rhythm and place-cell firing (red ticks) on a single run and (11, 12). This selffalse-co ...
Excitatory_Inhibitory_Neural_Network_1
Excitatory_Inhibitory_Neural_Network_1

... Theoretical Neuroscience, by Peter Dayan and Larry Abbott, MIT Press, 2005 pp. 266-269 The system studied here is one the simplest types of neural networks to exhibit oscillatory activity. It can be regarded as a simplified model of a fully-connected network comprised of a large number of excitatory ...
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whisker outline.doc

... This mainly columnar relay is largely due to the axonal organization. Most of the axons from excitatory neurons relate to the main column, as is illustrated here in this camera lucida drawing. You see in red the dendritic arbor confined to layer 4 of this excitatory cell and then most of the axons d ...
Special Seminar Dynamic Control of Dentritic Excitability During Hippocampal Rhythmic Activity
Special Seminar Dynamic Control of Dentritic Excitability During Hippocampal Rhythmic Activity

... Dendrites of pyramidal neurons receive about 50000 excitatory and inhibitory synapses. Our lab studies how dendrites integrate synaptic input and transform it into action potential output. Hippocampal theta rhythm is important for encoding and retrieval of memories. During hippocampal theta episodes ...
No Slide Title
No Slide Title

...  Some neurons use amino acids as transmitter substances, the most important being:  1. Glutamate: Also known as glutamic acid and is found throughout the brain. It produces EPSP's in the postsynaptic membrane but also directly affects axons by lowering their threshold of excitation, thus increasin ...
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T A BOLD window into brain waves

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Epilepsy - OMICS International
Epilepsy - OMICS International

... Electrophysiological studies suggest that reduced GABA (gamma-aminobutyric acid) inhibition contributes to the neuronal hyperexcitability that is characteristic of epilepsy [24]. Additionally, microdialysis studies have found heightened levels of extracellular glutamate the main excitatory neurotran ...
Slide () - AccessAnesthesiology
Slide () - AccessAnesthesiology

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Synaptic Transmission and Neurotransmitters
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Gamma band activity in the nuclei of the Reticular Activating System
Gamma band activity in the nuclei of the Reticular Activating System

... Introduction: During activated states (waking and paradoxical sleep), EEG responses are characterized by low amplitude, high frequency oscillatory activity in the gamma band range (~20-100 Hz). Gamma frequency oscillations have been proposed to participate in conscious perception, problem solving, m ...
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Learning Objectives

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Brain calculus: neural integration and persistent activity
Brain calculus: neural integration and persistent activity

... changes in firing rate induced with the intracellular injection of current. This supports the network hypothesis, because if the step changes were generated through mechanisms intrinsic to the cell recorded, such as through the activation of a persistent depolarizing current, then hyperpolarization ...
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Cellular-synaptic generation of EEG activity
Cellular-synaptic generation of EEG activity

... simultaneously study electrical activity on the surface and at the sites of the extracellular current generation. Electrical recording from deep brain structures using wire electrodes is one of the oldest methods in neuroscience. Local field potential measurements or "micro-EEG" (66) combined with r ...
Neurons Excitatory vs Inhibitory Neurons The Neuron and its Ions
Neurons Excitatory vs Inhibitory Neurons The Neuron and its Ions

... • Localist = 1 unit responds to 1 thing (e.g., digits, grandmother cell). ...
solutions
solutions

... 10. Search You Tube for educational videos related to biomedical instrumentation. Locate a video that teaches you something interesting (and relevant to ECE445). Briefly describe what you saw that was interesting and list the URL of the video. Answers will vary. See class notes for links to several ...
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Spike-and-wave



Spike-and-wave is the term that describes a particular pattern of the electroencephalogram (EEG) typically observed during epileptic seizures. A spike-and-wave discharge is a regular, symmetrical, generalized EEG pattern seen particularly during absence epilepsy, also known as ‘petit mal’ epilepsy. The basic mechanisms underlying these patterns are complex and involve part of the cerebral cortex, the thalamocortical network, and intrinsic neuronal mechanisms. The first spike-and-wave pattern was recorded in the early twentieth century by Hans Berger. Many aspects of the pattern are still being researched and discovered, and still many aspects are uncertain. The spike-and-wave pattern is most commonly researched in absence epilepsy, but is common in several epilepsies such as Lennox-Gastaut syndrome (LGS) and Ohtahara syndrome. Anti-epileptic drugs (AEDs) are commonly prescribed to treat epileptic seizures, and new ones are being discovered with less adverse effects. Today, most of the research is focused on the origin of the generalized bilateral spike-and-wave discharge. One proposal suggests that a thalamocortical (TC) loop is involved in the initiation spike-and-wave oscillations. Although there are several theories, the use of animal models has provided new insight on spike-and-wave discharge in humans.
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