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General anaesthesia: from molecular targets to neuronal
General anaesthesia: from molecular targets to neuronal

... by the range of physiological effects that they can induce. Very few of these effects, however, are common to all agents. The most intriguing of those that are is the ability to cause a reversible loss of consciousness (LOC) and, at higher concentrations, a state in which a human (or any other highe ...
PSNS 2nd Lecture 1433 - Home - KSU Faculty Member websites
PSNS 2nd Lecture 1433 - Home - KSU Faculty Member websites

... Two kinds of effects produced by ACh. Ach causes a fall in BP due to arteriolar vasodilatation and slowing of the heart A larger dose of ACh also produces bradycardia, further reducing BP Atropine blocks the effect of ACh in lowering BP Still under the influence of atropine, a much larger dose of AC ...
identification of cell types in brain slices of the inferior colliculus
identification of cell types in brain slices of the inferior colliculus

... parallel the ®bro-dendritic laminae. A second, less common neuron with a different dendritic morphology is also found in all species studied (e.g. the less-¯at neuron in the rat). In contrast, physiology suggests three or more cell types are present based on responses to binaural acoustic stimuli an ...
Spontaneous Spike Activity of Spinoreticular Tract Neurons During
Spontaneous Spike Activity of Spinoreticular Tract Neurons During

... to modulate the rostral transmission of sensory nociceptive information. Earlier evoked potential studies by Pompeiano and his colleagues suggested that a variety of spinal sensory pathways whose axons project through the medial leminiscus are regulated only during the rapid eye movement (REM) porti ...
Biological constraints limit the use of rapamycin
Biological constraints limit the use of rapamycin

... Background: Rapamycin-induced translocation systems can be used to manipulate biological processes with precise temporal control. These systems are based on rapamycin-induced dimerization of FK506 Binding Protein 12 (FKBP12) with the FKBP Rapamycin Binding (FRB) domain of mammalian target of rapamyc ...
Sequential Development of Electrical and Chemical Synaptic
Sequential Development of Electrical and Chemical Synaptic

... this camera has 512 ⫻ 512 pixels, but we normally binned at 4 ⫻ 4 pixels, yielding a 128 ⫻ 128 pixel image. The quantum efficiency of the camera at the coumarin emission peak was 80%. The CCD chip was maintained at ⫺25°C during imaging. Images were stored using the software package Win-View/32 (Rope ...
relation between cell size and response characteristics of
relation between cell size and response characteristics of

... Finally, these two neuronal populations are linked: vestibulospinal fibers from the 1LVN excite mono- and polysynaptically ipsilateral extensor motoneurons (Lund and Pompeiano, 1968; Grillner et al., 1970). For these reasons, we decided to record the unit activity from the selected population of LVN ...
LWW PPT Slide Template Master
LWW PPT Slide Template Master

... • Sensory neurons carry information from receptors • Motor neurons for voluntary movement • One motor neuron between spinal cord and effector • Only one type of effector: skeletal muscle • See Figure 7-29 ...
Electrophysiological evidence that noradrenergic neurons of the rat
Electrophysiological evidence that noradrenergic neurons of the rat

... 1985) were routinely done via the saline-containing barrel. Dorsal raphe serotonergic neurons were first localized using the DRN stereotaxic coordinates. The micropipettes with a 15° caudo-rostral inclination were placed on the brain surface 4 mm posterior to the lambda, 0-0.4 mm lateral to the midl ...
On the Role of the Pontine Brainstem in Vocal Pattern Generation: A
On the Role of the Pontine Brainstem in Vocal Pattern Generation: A

... sensor (see Fig. 4). In the same way, the end of the vocalization was determined. Statistical analysis. The Pearson’s correlation was used to examine the correlation between call duration and the duration of the corresponding neuronal activity. Because the number of measures per neuron differed, a c ...
Subthalamic Stimulation-Induced Synaptic Responses in Substantia
Subthalamic Stimulation-Induced Synaptic Responses in Substantia

... mode or in an irregular pattern punctuated with slow bursts typically comprising two to six action potentials (Bunney et al. The costs of publication of this article were defrayed in part by the payment of page charges. The article must therefore be hereby marked “advertisement” in accordance with 1 ...
Central mechanisms regulating coordinated cardiovascular and
Central mechanisms regulating coordinated cardiovascular and

... clearly identify the particular neurons and pathways that mediate stress-evoked increases in arterial pressure, sympathetic activity, and respiratory activity. Furthermore, c-Fos expression occurs only after sustained stimulation of neurons and so this method cannot be used to identify cell populati ...
the biological perspective
the biological perspective

... Two special types of glial cells, called oligodendrocytes and Schwann cells, generate a layer of fatty substances called myelin. Oligodendrocytes produce myelin for the neurons in the brain and spinal cord (the central nervous system); Schwann cells produce myelin for the neurons of the body (the pe ...
Slide 1
Slide 1

... The pain from the burning heat of the candle flame stimulates the afferent nerve fibers, which carry the message up to the interneurons in the middle of the spinal cord. The interneurons then send a message out by means of the efferent nerve fibers, causing the hand to jerk away from the flame. ...
An Olfactory Sensory Map in the Fly Brain
An Olfactory Sensory Map in the Fly Brain

... We have isolated the “complete” repertoire of genes encoding the odorant receptors in Drosophila and employ these genes to provide a molecular description of the organization of the peripheral olfactory system. The repertoire of Drosophila odorant receptors is encoded by 57 genes. Individual sensory ...
Skeletal System
Skeletal System

... Because the cord does not reach the end of the vertebral column, the lumbar and sacral spinal nerve roots angle sharply downward and travel inferiorly before reaching their intervertebral foramina This collection of nerve roots at the inferior end of the vertebral canal is called the cauda equina Th ...
1-1 Test Bank Liebgott: The Anatomical Basis of Dentistry, 3rd
1-1 Test Bank Liebgott: The Anatomical Basis of Dentistry, 3rd

... Efferent fibers. Efferent fibers are axons that carry impulses away from the CNS to muscles and glands. They also are referred to as motor, or descending, fibers. Afferent fibers are axons that carry impulses toward the CNS. REF: 1-23 40. General sensory (also known as somatic sensory) pathways feat ...
Document
Document

... Efferent fibers. Efferent fibers are axons that carry impulses away from the CNS to muscles and glands. They also are referred to as motor, or descending, fibers. Afferent fibers are axons that carry impulses toward the CNS. REF: 1-23 40. General sensory (also known as somatic sensory) pathways feat ...
Jukic et al. SUPPLEMANTARY SUPLEMENTARY METHODS En1+/
Jukic et al. SUPPLEMANTARY SUPLEMENTARY METHODS En1+/

... monoaminergic neuronal specification in non-mammals differ substantially from mammalian pathways (Hegarthy et al., 2013). 3. Only data relevant for midbrain DA or rostral 5HT sub-populations were considered, since they are affected in En1+/Otx2 mutants and relevant to psychiatric disorders. In contr ...
The mirror neuron system and the consequences of its
The mirror neuron system and the consequences of its

... handling objects (food) with the help of tools (sticks, pliers) - some mirror neurons start firing after repeated observation  This is evidence for the fact that the MNS can be shaped by experience and accounts for observational learning ...
08_NervousSystem
08_NervousSystem

... The Central Nervous System Key Note The sensory and motor nuclei (gray matter) of the spinal cord surround the central canal. Sensory nuclei are dorsal, motor nuclei are ventral. A thick layer of white matter consisting of ascending and descending axons covers the gray matter. These axons are organ ...
2 Brain and Classical Neural Networks
2 Brain and Classical Neural Networks

... range of 100/s, or even smaller in some areas, at about 50/s. It should be noticed that this rather exotic neural communication mechanism works very efficiently and it is employed universally, both by vertebrates and invertebrates. The vertebrates have gone even further in perfection, by protecting th ...
Serotonin Depletion In Vivo Inhibits the
Serotonin Depletion In Vivo Inhibits the

... amount of branching within the OGTN varied between neurons but, when present, rarely consisted of more than one or two fine branches. On passing through the OGTN, the OGT projects bilaterally to the eyestalks where it innervates the lateral protocerebrum (Fig. 1) (Helluy et al., 1995). ...
Autonomic NS
Autonomic NS

... parasympathetic axons. • Cardiac plexus- heart. • Pulmonary plexus- the bronchial tree. • Celiac plexus- largest. Supplies the stomach, spleen, pancreas, liver, gallbladder, and ...
Figure 15.9
Figure 15.9

... parasympathetic axons. • Cardiac plexus- heart. • Pulmonary plexus- the bronchial tree. • Celiac plexus- largest. Supplies the stomach, spleen, pancreas, liver, gallbladder, and ...
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Circumventricular organs

Circumventricular organs (CVOs) are structures in the brain that are characterized by their extensive vasculature and lack of a normal blood brain barrier (BBB). The CVOs allow for the linkage between the central nervous system and peripheral blood flow; additionally they are an integral part of neuroendocrine function. The lack of a blood brain barrier allows the CVOs to act as an alternative route for peptides and hormones in the neural tissue to the peripheral blood stream, while still protecting it from toxic substances. CVOs can be classified into (a) sensory and (b) secretory organs. The sensory organs include the area postrema (AP), the subfornical organ (SFO) and the vascular organ of lamina terminalis. They have the ability to sense plasma molecules and then pass that information into other regions of the brain. Through this, they provide direct information to the autonomic nervous system from the systemic circulation. The secretory organs include the subcommissural organ (SCO), the posterior pituitary, the pineal gland, the median eminence and the intermediate lobe of the pituitary gland. These organs are responsible for secreting hormones and glycoproteins into the peripheral vascular system using feedback from both the brain environment and external stimuli.All of the circumventricular organs, besides the SCO, contain extensive vasculature and fenestrated capillaries which leads to a ‘leaky’ BBB at the site of the organs. Furthermore, all CVOs contain neural tissue, allowing them to play a role in the neuroendocrine system. It is highly debated if the choroid plexus can be included as a CVO. It has a high concentration of fenestrated capillaries, but its lack of neural tissue and its primary role of producing cerebrospinal fluid (CSF) usually excludes the choroid plexus from the CVO classification.Research has also linked CVOs to body fluid regulation, cardiovascular functions, immune responses, thirst, feeding behavior and reproductive behavior.
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