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... signalling is widely believed to be regulated in an autocrine feedback loop by another Egfr ligand, Spitz, and the Egfr inhibitor Argos. On p. 2893, however, Laura Nilson and colleagues challenge this view by showing that the SpitzArgos feedback loop is not required for dorsal appendage patterning a ...
Lesson Plan  - University of Washington
Lesson Plan - University of Washington

... Review: Peripheral nerves, those that go to legs, arms, and other extremities, contain both sensory neurons and motor neurons. Last week you manually stimulated the nerve in the cockroach leg. This stimulation elicited action potentials in the sensory neurons which travels to the brain and tells the ...
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PDF

... signalling is widely believed to be regulated in an autocrine feedback loop by another Egfr ligand, Spitz, and the Egfr inhibitor Argos. On p. 2893, however, Laura Nilson and colleagues challenge this view by showing that the SpitzArgos feedback loop is not required for dorsal appendage patterning a ...
Lectures for 5th week: Visual System I
Lectures for 5th week: Visual System I

... the LGN further along the visual pathway) have concentric receptive fields with either a centre-off or centre-on surround. Cell fires rapidly when light hits centre, is inhibited when light is over the surround, and halfway across –no activity. As such, these cells are ideal for signalling changes i ...
Membrane Domains and Membrane Potential
Membrane Domains and Membrane Potential

... +55mV). When the conductance to Na+ goes back to its original value, the membrane potential will return to the resting potential. If the neuron is at resting potential (-70mV) and the conductance to K+ increases, the membrane potential will be hyperpolarized (it will move toward -90mV). Transmission ...
Reconstruction of Natural Scenes from Ensemble Responses in the
Reconstruction of Natural Scenes from Ensemble Responses in the

... spatiotemporal white-noise stimuli and the reverse correlation method (Sutter, 1987; Reid et al., 1997). Only X cells were selected for f urther studies because they are presumably involved in processing the spatial details of visual scenes (Wässle and Boycott, 1991) and they have relatively linear ...
Introduction to Neurophysiology
Introduction to Neurophysiology

... The transmitter (direct) gated channels in the muscle are permeable to both Na and K. These channels are also not responsive to voltage which means that they are not regenerative. The depolarization varies with the amount of transmitter released. ...
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The Endocrine System
The Endocrine System

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... Bipolar Neurons  Bipolar neurons.  One axon and one main dendrite.  Retina of the eye, inner ear, and the olfactory areas of the ...
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Larry M. Jordan, Urszula Sławińska
Larry M. Jordan, Urszula Sławińska

... FIGURE 17.3 Models of the CPG. (A) The half-center model of Graham-Brown, as modified by Lundberg to explain the findings in LDOPA-treated spinal cats. Stimulation of ipsilateral flexor-reflex afferents (iFRAs) produced late-long lasting excitation of flexor motoneurons, while stimulation of contra ...
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... Brain stimulation may directly activate the brain's “reinforcement” system, eliminating the need for natural reinforcers (e.g., food). ...
Biochemistry
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A Biologically Plausible Spiking Neuron Model of Fear Conditioning

... models, there are advantages to choosing LIF neurons: they capture a sufficient level of biological detail, and at the same time are computationally efficient to simulate. The properties of the LIF neurons used (for example their post-synaptic time constants and refractory periods) have been chosen ...
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... – emergency, embarrassment, excitement, exercise ...
The Nervous System - Blackwell Publishing
The Nervous System - Blackwell Publishing

... between different parts of your brain, and between your brain and the rest of your body. As you were waiting, your body posture was being continually monitored and adjusted: you did this by constantly updating proprioceptive information from sensors located in your joints and muscles, and combining ...
The Nervous System - INAYA Medical College
The Nervous System - INAYA Medical College

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Participation of γ-Aminobutyric Acid Mechanism in the Nucleus
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... Participation of γ-Aminobutyric Acid Mechanism in the Nucleus Tractus Solitarius in Electroacupuncture Reversal of Phenylbiguanide Induced Cardiopulmonary Depressor Effects Megumi Sugimoto, Stephanie Chow Mentors: Stephanie Tjen-a-looi, John Longhurst In recent years, electroacupuncture (EA) has gai ...
Tracing Brain Pathways: Mapping the Neurons
Tracing Brain Pathways: Mapping the Neurons

... PRV is injected into the peripheral muscles of the rodent eye and passed back neuron by neuron, an effective trans-neuronal tracing technique. The highly selective PRV is taken up by neurons responsible for the function and activity of the eyes, specifically omnipause neurons (OPNs) and excitatory b ...
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...  These alpha motor neurons, also referred to as lower motor neurons, are the only means by which the nervous system can exercise control over body movements, whether voluntary or involuntary; ...
Worm Phyla - Shah's Aquatic Science
Worm Phyla - Shah's Aquatic Science

... rings) and appear flat most no more than a few millimeters thick. have tissues and internal organs systems bilateral symmetry, cephalization (which means they have a head!) Flatworm video ...
Lecture-4b
Lecture-4b

... Do they switch off inspiration during normal respiratory cycle? Unlikely - only activated at large >>1litre tidal volumes Maybe important in new born babies May prevent over-inflation lungs during hard exercise? ...
Repetition and the brain: neural models of stimulus
Repetition and the brain: neural models of stimulus

... The purpose of this review is to consider several kinds of neural models that have been proposed to account for repetition suppression (RS). We focus primarily on studies using visually presented objects and their effects on the ventral object processing stream, to maximize overlap between monkey an ...
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Stimulus (physiology)



In physiology, a stimulus (plural stimuli) is a detectable change in the internal or external environment. The ability of an organism or organ to respond to external stimuli is called sensitivity. When a stimulus is applied to a sensory receptor, it normally elicits or influences a reflex via stimulus transduction. These sensory receptors can receive information from outside the body, as in touch receptors found in the skin or light receptors in the eye, as well as from inside the body, as in chemoreceptors and mechanorceptors. An internal stimulus is often the first component of a homeostatic control system. External stimuli are capable of producing systemic responses throughout the body, as in the fight-or-flight response. In order for a stimulus to be detected with high probability, its level must exceed the absolute threshold; if a signal does reach threshold, the information is transmitted to the central nervous system (CNS), where it is integrated and a decision on how to react is made. Although stimuli commonly cause the body to respond, it is the CNS that finally determines whether a signal causes a reaction or not.
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