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The nervous system
The nervous system

... the cells to one another, to centers throughout the body or to other neurons. These neurons operate on excitation or inhibition and although nerve cells can vary in size and location their communication with one another determines their function. These nerves conduct impulses from sensory receptors ...
3/26
3/26

... Nerves allow us to perceive the environment while the brain integrates the incoming signals to determine an appropriate response. CB 48.3 ...
Distinction of a left or right hand keypress
Distinction of a left or right hand keypress

... Jorge Del Río Vera ...
Linköping University Post Print Neuroscience: Light moulds plastic brains
Linköping University Post Print Neuroscience: Light moulds plastic brains

... dopaminergic neurons, this observation was perhaps expected: it is unlikely that additional neurons could be generated de novo within the relatively short time frame of only two hours. Instead, it seems that pre-existing neurons expressing a different neurotransmitter now coproduce dopamine. Dulcis ...
Object Recognition and Learning using the BioRC Biomimetic Real
Object Recognition and Learning using the BioRC Biomimetic Real

... have 300 inputs, there are “N choose M” or “10,000 choose 300” combinations of inputs that make the neural circuit fire at the final output. Thus, we require N!/(N-M)!M! combinations to be checked, so the first stage of the neural network has N!/(N-M)!M! neurons, each of which has M inputs. We could ...
Harnessing Plasticity to Reset Dysfunctional Neurons
Harnessing Plasticity to Reset Dysfunctional Neurons

... descriptions” and their allegiance in response to demands. The mechanisms underlying this process are complex, have varying time courses (from milliseconds to months), and are incompletely understood. They include changes in synaptic strength, the pruning and growth of neuronal connections, and even ...
Nervous System Cells
Nervous System Cells

... potential to simply continue along a post synaptic membrane • Chemical synapses- occurs where presynatptic cells release chemical transmitters [neurotransmitters] across a tiny gap to the postsynaptic cell possibly inducing an action potential there. http://www.blackwellpublishing.com/matthe ws/nmj. ...
Nervous Tissue: Support Cells
Nervous Tissue: Support Cells

... terminals are separated from the next neuron by a gap (they never really touch) – Synaptic cleft — gap (space) between adjacent neurons – Synapse — junction between nerves ...
Introduction to Neural Networks
Introduction to Neural Networks

... Definition of Neural Networks • An information processing system that has been developed as a generalization of mathematical models of human cognition or neurobiology, based on the assumptions that – Information processing occurs at many simple elements called neurons. – Signals are passed between ...
Structural arrangement of the nervous sytem. Blood-brain
Structural arrangement of the nervous sytem. Blood-brain

...  transport of trophic and other signalling molecules from the periphery to the neuronal body  some neurotropic viruses such as poliomyelitis, herpes, and rabies and neurotoxins enter peripheral nerve endings and ascend to infect the cell body via retrograde transport ...
THE NERVOUS SYSTEM: Communication
THE NERVOUS SYSTEM: Communication

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Emotion: Cellular Level
Emotion: Cellular Level

... Emotions can be defined as 'states elicited by reinforcing stimuli' (Rolls 1986), whereby the association (innately, through conditioning or learning) of reinforcer stimuli with a behavior is responsible for its emotional coloring. At the cellular level, learning has been hypothetize to reply on syn ...
Normal Edema
Normal Edema

... disease processes affect some groups of cells more than others (‘selective vulnerability’), other disease processes could affect other areas more. • Not all areas in the brain are equal: most areas in the brain have specific functions: a same disease process in two different areas of the brain, ofte ...
Name
Name

... Name: ___________________________________ Date: ______________ ...
Neuroscience
Neuroscience

... Neurons contain cytoplasm, mitochondria and other organelles. Neurons carry out basic cellular processes such as protein synthesis and energy production. ...
BASAL GANGLIA
BASAL GANGLIA

... A: An injection of antergograde tracer was made in a small site in the motor cortex (area 4) representing the foot. In the same hemisphere , a small site in the pallidum was injected with retrograde tracer. Both the labeled axon projections from the cortex to terminal sites in the striatum and the ...
AP Psychology - HOMEWORK 9
AP Psychology - HOMEWORK 9

... ________________________. Increasing a stimulus above this level will not increase the neural impulse's intensity. This phenomenon is called an ______-______-________________ response. (2 pts) ...
Synapses
Synapses

... Requires G-protein coupled receptor on post-synaptic membrane G-protein activates an enzyme on the cytoplasmic side of the membrane May involve degradative enzymes May involve reuptake transporters on pre-synaptic membrane Examples: transmission of smell, control of cardiac muscle ...
Chapter 3
Chapter 3

... b/c image processed in L hemisphere • projected to L visual field, the S cannot identify verbally, but can use L hand to identify by touch ...
Exam 3 Review KEY
Exam 3 Review KEY

... endings and respond chiefly to temperature and pain such as Merkel discs and hair follicle receptors. Encapsulated receptors are surrounded by tissue. Examples would be Meissner’s and Pacinian corpuscles. 24) Endoneurium is the nerve covering around individual fibers. Fascicles are groups of nerve f ...
Classifications of Neurons 1. Function 2. Structure 3. Shape
Classifications of Neurons 1. Function 2. Structure 3. Shape

... Planes of Section Coronal or frontal perpendicular to the neuraxis perpendicular to ground apply only to brain Sagittal parallel to neuraxis perpendicular to ground midsagittal = axis of symmetry Horizontal parallel to ground parallel to neuraxis applies only to brain Transverse perpendicular to ne ...
Print this Page Presentation Abstract Program#/Poster#: 532.07/GG10
Print this Page Presentation Abstract Program#/Poster#: 532.07/GG10

... which the output is modulated by the summed local activity. In these models, the region of the sensory space that is pooled to produce suppression to a neuron is larger than that for summation. The neural implementation of normalization in the visual cortex is thought to involve inhibitory neurons t ...
Brain and Neuron Quiz Key
Brain and Neuron Quiz Key

... Fill in the blanks with the correct words from the word bank. Some words may be used more than once, and some may not be used at all. 1. The frontal lobes control motor function. ...
Chapter 2 Summary
Chapter 2 Summary

... Positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) scans use changes in blood flow to measure brain activity ...
File
File

... System • STRUCTURES: brain, spinal cord, & peripheral nerves • FUNCTION: Recognizes and coordinates the body’s response to changes in its internal and external environments ...
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Optogenetics



Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.
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