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Nervous System - Phoenix Union High School District
Nervous System - Phoenix Union High School District

... d) oligodendrocytes- branched; connect thick nerve fibers; produce a myelin sheath around neurons. ...
Early Brain Development
Early Brain Development

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Optical controlling reveals time-dependent roles for adult
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... adult-born cells change markedly as they mature, they may have distinct roles at different stages following integration into hippocampal circuits. Adult-born dentate granule cells (DGCs) extend dendrites receive functional input from the existing neural circuits as early as 2 weeks after birth. Inpu ...
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Visual Cortical Dynamics Charles Gilbert The Rockefeller University
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ppt - Le Moyne College

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CP Herry Nature December 8, 2011 - Host Laboratories / Research

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Nervous System - Lemon Bay High School
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Nerve cells - WordPress.com

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... (1) As the electrode moves up or down through the layers of the striate cortex it finds neurons that respond to stimulation from about the same location on the retina (2) simple and complex, cells that all prefer the same orientation – the cells respond to line orientations that are at the same degr ...
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Neuroembryology II_UniTsNeurosciAY1415_06a

... lacZ-expressor plasmid and a CR-marker plasmid (expressing EGFP under the control of a promoter which specifically fires in CR-cells) into the E11.5 telencephalon, at different locations. After a few days, they studied the resulting distribution of the two markers and could prove that: (1) CR-cells ...
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Optogenetics



Optogenetics (from Greek optikós, meaning ""seen, visible"") is a biological technique which involves the use of light to control cells in living tissue, typically neurons, that have been genetically modified to express light-sensitive ion channels. It is a neuromodulation method employed in neuroscience that uses a combination of techniques from optics and genetics to control and monitor the activities of individual neurons in living tissue—even within freely-moving animals—and to precisely measure the effects of those manipulations in real-time. The key reagents used in optogenetics are light-sensitive proteins. Spatially-precise neuronal control is achieved using optogenetic actuators like channelrhodopsin, halorhodopsin, and archaerhodopsin, while temporally-precise recordings can be made with the help of optogenetic sensors for calcium (Aequorin, Cameleon, GCaMP), chloride (Clomeleon) or membrane voltage (Mermaid).The earliest approaches were developed and applied by Boris Zemelman and Gero Miesenböck, at the Sloan-Kettering Cancer Center in New York City, and Dirk Trauner, Richard Kramer and Ehud Isacoff at the University of California, Berkeley; these methods conferred light sensitivity but were never reported to be useful by other laboratories due to the multiple components these approaches required. A distinct single-component approach involving microbial opsin genes introduced in 2005 turned out to be widely applied, as described below. Optogenetics is known for the high spatial and temporal resolution that it provides in altering the activity of specific types of neurons to control a subject's behaviour.In 2010, optogenetics was chosen as the ""Method of the Year"" across all fields of science and engineering by the interdisciplinary research journal Nature Methods. At the same time, optogenetics was highlighted in the article on “Breakthroughs of the Decade” in the academic research journal Science. These journals also referenced recent public-access general-interest video Method of the year video and textual SciAm summaries of optogenetics.
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