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A neurocomputational model of the mammalian fear
A neurocomputational model of the mammalian fear

... Chapter 2, Fear conditioning, introduces the topic of fear conditioning. The results of several classic fear conditioning experiments are presented. Chapter 3, Anatomy of the fear conditioning circuit, discusses the regions of the brain involved in the fear conditioning circuit. Their function, as i ...
Title here - The Brain Tumour Charity
Title here - The Brain Tumour Charity

... The specialist will ask questions about your health and give you a physical examination. They will also test your nervous system (called a ‘neurological examination’). This involves looking at your vision, hearing, alertness, muscle strength, co-ordination and reflexes. They may also look at the bac ...
Schwann cells
Schwann cells

... The sensory division of the PNS brings information to the CNS from receptors in peripheral tissues and organs. ...
A Model of Prefrontal Cortical Mechanisms for Goal-directed Behavior Michael E. Hasselmo Abstract
A Model of Prefrontal Cortical Mechanisms for Goal-directed Behavior Michael E. Hasselmo Abstract

... has multiple units in vector a receiving input from the thalamus about current sensory state or proprioceptive feedback about motor output (actions). The population gi receives input spreading back from the goal via connections Wg from other minicolumns. The population go receives activity spreading ...
Abnormal gray matter aging in chronic pain patients
Abnormal gray matter aging in chronic pain patients

... are shown schematically in Fig. 4b. In the right thalamus, the partial correlation coefficient between age and GM volume was no longer significant when controlling for duration (rage = 0.646, p = 0.005; rage · duration = 0.447, p = 0.082), whereas duration remained significant when age was included ...
The effects of normal aging on myelin and nerve fibers: A review
The effects of normal aging on myelin and nerve fibers: A review

... that occurs with increasing age in monkeys (e.g. Moss et al., 1999). It is suggested that the reason for this correlation between myelin sheath alterations and decline in cognition is because damage to myelin sheaths results in a decrease in conduction velocity along nerve fibers. For example, Xi et ...
Feedforward and feedback frequency
Feedforward and feedback frequency

... (~15 to 30 Hz) frequency range (Fig. 2A, bottom) (3, 12). A simple coupled excitatory-inhibitory system as described here is useful for studying the response of early visual neurons to incoming visual stimuli. For instance, recordings of local field potentials show that increasing the contrast of a ...
A simultaneous ERP/fMRI investigation of the P300 aging effect
A simultaneous ERP/fMRI investigation of the P300 aging effect

... level with younger participants, the differences in P300 topography have been proposed to represent the compensatory activation of additional neural networks. Fabiani et al. (1998) explored this issue by dividing their elderly participant group according to those individuals who exhibited a frontal ...
A Hebbian learning rule gives rise to mirror neurons and links them
A Hebbian learning rule gives rise to mirror neurons and links them

... We have learned much about the integration of sensory inputs into motor systems from single neuron studies examining responses during motor production and during matched sensory states. Among the key findings are mirror neurons that fire similarly when an animal executes a motor act and when it sees ...
Chapter 11: Functional Organization of Nervous Tissue
Chapter 11: Functional Organization of Nervous Tissue

... contain the nucleus. B) are numerous extensions from each neuron. C) do not have a trigger zone. D) have a distal portion that branches to form the presynaptic terminals or terminal boutons. E) do not have a resting membrane potential. Answer: d Level: 1 ...
File: Chap011, Chapter 11: Functional Organization of Nervous Tissue
File: Chap011, Chapter 11: Functional Organization of Nervous Tissue

... contain the nucleus. B) are numerous extensions from each neuron. C) do not have a trigger zone. D) have a distal portion that branches to form the presynaptic terminals or terminal boutons. E) do not have a resting membrane potential. Answer: d Level: 1 ...
Glia–Neuron Interactions in Nervous System Function
Glia–Neuron Interactions in Nervous System Function

... Before embarking on a discussion of glia–neuron interactions, it is important to define each cell type. This is no small matter, since valid comparisons of glia–neuron interactions across diVerent species rest on the assumption that ...
Age-dependent effect of cholinergic lesion on dendritic morphology
Age-dependent effect of cholinergic lesion on dendritic morphology

... could either reflect or result in changes in plasticity. Previously, we used ibotenic acid lesions of the NBM to begin to investigate potential age-related changes in frontal cortical plasticity [61,64]. The NBM is a basal forebrain cholinergic nucleus, and projections from the NBM modulate cortical ...
Synapses formed by normal and abnormal hippocampal mossy fibers
Synapses formed by normal and abnormal hippocampal mossy fibers

... denervation of their target cells in the molecular layer, granule cells “sprout” new axon collaterals and extend them into the dentate inner molecular layer (Nadler et al. 1980; Laurberg and Zimmer 1981; Frotscher and Zimmer 1983; Sloviter et al. 2006). This sprouting is a consistent feature that fo ...
Hypothalamus15
Hypothalamus15

... (sympathetic trunk). • Parasympathetic: peripheral ganglia located close to target organs (i.e., terminal ganglia of X). • Note: organs distal to splenic flexure of colon served by sacral parasympathetic nuclei. • For both systems, anatomical location of central neurons is analogous. ...
The habenular nuclei - Philosophical Transactions of the Royal
The habenular nuclei - Philosophical Transactions of the Royal

... the midbrain/hindbrain. In this review, we will focus on the anatomy and connectivity of the habenulae and the interpeduncular nucleus (IPN). The latter is a major target of habenular efferent connectivity in all vertebrates and consequently plays a pivotal role in the modulation of nuclei downstrea ...
Document
Document

... More in details, NGF consists of three subunits, a, b and g which interact to form a 7S complex of approximately 27 kDa in weight. The 7S complex contains two identical 118 amino acid b chains, which are solely responsible for the trophic activity of NGF. Mature b-NGF is synthesized from prepro-b NG ...
Increased cell proliferation and granule cell number in the dentate
Increased cell proliferation and granule cell number in the dentate

... All antisera used in immunohistochemical experiments were obtained from commercial sources. Neurons were identified by using a mouse monoclonal antibody that recognizes the neuron-specific nuclear protein NeuN (MAB377, Chemicon International, Temecula, CA; diluted 1:1,000). This antibody was raised ...
Identification of key signaling molecules involved - diss.fu
Identification of key signaling molecules involved - diss.fu

... Thermoregulation is a crucial homeostatic function orchestrated by the central nervous system for all homothermic animals to obtain an optimal thermal environment. The thermoregulatory center of homothermic animals is located in the preoptic area of the hypothalamus, which not only receives the temp ...
Avian brains and a new understanding of
Avian brains and a new understanding of

... With these challenges to the classical view of the subpallial relationships among birds, reptiles and mammals came challenges to the classical view of the relationships among their pallia. The mammalian pallium includes the areas known as palaeocortex, archicortex and neocortex; and has been said, m ...
Specialized Elements of Orbitofrontal Cortex in Primates
Specialized Elements of Orbitofrontal Cortex in Primates

... neurons, or in tissue stained for markers that label distinct groups of pyramidal neurons or inhibitory interneurons (e.g., Ref. 3). The fingerprints in FIGURE 2 were constructed using three markers for different architectonic areas of the orbitofrontal cortex. Grouping architectonic areas by type, ...
1 Introduction to Behavioral Endocrinology
1 Introduction to Behavioral Endocrinology

... When considering the dose, some investigators might be tempted to begin with high doses of a hormone just to be sure that they see an effect. Results from high doses, however, can be very misleading. A bell-shaped curve showing the relationship between a hormone and a behavior is frequently found in ...
SMELL & TASTE
SMELL & TASTE

... • Most mammals only become sexually aroused in the presence of pheromones • Increased likelihood of pregnancy • Synchronization of estrus cycles • Mutual recognition of mother and offspring • Territory marking (e.g. dogs) ...
Growth and Targeting of Subplate Axons and Establishment of Major
Growth and Targeting of Subplate Axons and Establishment of Major

... extend subcortically by passing through an axonal pathway, termed the internal capsule, that forms in the basal telencephalon. Layer 6 axons extend through the internal capsule and directly into the thalamus. Layer 5 axons pass through the full extent of the internal capsule and extend into its cont ...
video slide - Buena Park High School
video slide - Buena Park High School

... The depolarization of the action potential spreads to the neighboring region of the membrane, re-initiating the action potential there. To the left of this region, the membrane is repolarizing as K+ flows outward. ...
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Feature detection (nervous system)

Feature detection is a process by which the nervous system sorts or filters complex natural stimuli in order to extract behaviorally relevant cues that have a high probability of being associated with important objects or organisms in their environment, as opposed to irrelevant background or noise. Feature detectors are individual neurons – or groups of neurons – in the brain which code for perceptually significant stimuli. Early in the sensory pathway feature detectors tend to have simple properties; later they become more and more complex as the features to which they respond become more and more specific. For example, simple cells in the visual cortex of the domestic cat (Felis catus), respond to edges – a feature which is more likely to occur in objects and organisms in the environment. By contrast, the background of a natural visual environment tends to be noisy – emphasizing high spatial frequencies but lacking in extended edges. Responding selectively to an extended edge – either a bright line on a dark background, or the reverse – highlights objects that are near or very large. Edge detectors are useful to a cat, because edges do not occur often in the background “noise” of the visual environment, which is of little consequence to the animal.
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