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... determine whether excess Ube3a causes autism behavioral deficits via actions in the neuronal cytoplasm/ synapse or nucleus, we engineered a nuclear importing peptide signal to the C-terminus of Ube3a. We have further engineered the Ube3a transgene to permit neuron subtype and brain region specific i ...
... determine whether excess Ube3a causes autism behavioral deficits via actions in the neuronal cytoplasm/ synapse or nucleus, we engineered a nuclear importing peptide signal to the C-terminus of Ube3a. We have further engineered the Ube3a transgene to permit neuron subtype and brain region specific i ...
the amygdala and reward
... three of the five behaviours that argue against a role for the amygdala in reward processing. What might underlie the intact food preferences and object preferences of animals that have no amygdala? One possibility is that stimulus representations that are stored in the cortex can be used to guide b ...
... three of the five behaviours that argue against a role for the amygdala in reward processing. What might underlie the intact food preferences and object preferences of animals that have no amygdala? One possibility is that stimulus representations that are stored in the cortex can be used to guide b ...
2011-Morrison and Nakamura_review
... revealed that many neurons densely clustered in the external lateral subnucleus of the LPB (LPBel) in the pons are both activated (Fos expression) following cold (4°C) exposure (32) and retrogradely labeled following tracer injections into the POA (Figure 4) (27), indicating that LPBel neurons direc ...
... revealed that many neurons densely clustered in the external lateral subnucleus of the LPB (LPBel) in the pons are both activated (Fos expression) following cold (4°C) exposure (32) and retrogradely labeled following tracer injections into the POA (Figure 4) (27), indicating that LPBel neurons direc ...
19 CORTICAL PROJECTIONS FROM TWO PRESTRIATE AREAS IN
... In the visual system from retina to cortex the diversity of cell types as judged by their electrophysiological response properties may be explained by the repeated convergence of one group of cells upon another, using both excitatory and inhibitory mechanismsL Such a convergence starts within the la ...
... In the visual system from retina to cortex the diversity of cell types as judged by their electrophysiological response properties may be explained by the repeated convergence of one group of cells upon another, using both excitatory and inhibitory mechanismsL Such a convergence starts within the la ...
Predicting spike timing of neocortical pyramidal neurons by simple
... and inhibitory components. Despite the temporal precision under appropriate stimulation conditions, neuronal responses can be highly variable across trials, in particular in visual cortex (Heggelund and Albus, 1978; Buracas et al., 1998), but much less so in auditory cortex (De Weese and Zador, 2003 ...
... and inhibitory components. Despite the temporal precision under appropriate stimulation conditions, neuronal responses can be highly variable across trials, in particular in visual cortex (Heggelund and Albus, 1978; Buracas et al., 1998), but much less so in auditory cortex (De Weese and Zador, 2003 ...
The Morphology of Physiologically Identified GABAergic Neurons in
... anatomical connectivity, it quickly became evident that corticothalamic fibers, passing to a particular dorsal thalamic nucleus, and thalamocortical fibers emanating from that dorsal thalamic nucleus, give rise to terminations in the same part of the reticular nucleus as they pass through it. Moreov ...
... anatomical connectivity, it quickly became evident that corticothalamic fibers, passing to a particular dorsal thalamic nucleus, and thalamocortical fibers emanating from that dorsal thalamic nucleus, give rise to terminations in the same part of the reticular nucleus as they pass through it. Moreov ...
Affective percept and voluntary action: A hypothesis
... systems. Accordingly, we will distinguish food affective stimuli, esthetic affective stimuli, etc. Different affective stimuli evoke the corresponding affective percepts and the latter can be divided according to the same four criteria. The division of affective percepts according to criteria 1 and ...
... systems. Accordingly, we will distinguish food affective stimuli, esthetic affective stimuli, etc. Different affective stimuli evoke the corresponding affective percepts and the latter can be divided according to the same four criteria. The division of affective percepts according to criteria 1 and ...
Neuregulin-1/ErbB4 signaling regulates Kv4.2-mediated - AJP-Cell
... used for background subtraction and for quantification of immunoblotting data. The results were analyzed using one-way ANOVA for comparisons between multiple groups and using Student’s t-tests for comparisons between two samples. The values are given as the means ⫾ SE with n as the number of neurons ...
... used for background subtraction and for quantification of immunoblotting data. The results were analyzed using one-way ANOVA for comparisons between multiple groups and using Student’s t-tests for comparisons between two samples. The values are given as the means ⫾ SE with n as the number of neurons ...
Banbury notes 05 - University of Illinois Archives
... entirely to learn – ultimately some learning but far behind Lesion dentate nucleus in controls reduces them to KO equivalent, implicates cerebellum specifically Conditional KO – CRE recombinase : Neo (hypomorph—low expression); CKO; KO Can turn on full expression of protein late in life; Want to stu ...
... entirely to learn – ultimately some learning but far behind Lesion dentate nucleus in controls reduces them to KO equivalent, implicates cerebellum specifically Conditional KO – CRE recombinase : Neo (hypomorph—low expression); CKO; KO Can turn on full expression of protein late in life; Want to stu ...
Sonic hedgehog and cerebellum development
... Lee et al., 1997; Ruiz i Altaba, 1998), SHH could thus act in an autocrine manner in early EGL cells. SHH secreted from Purkinje neurons could then act on oEGL cells and in cells within the PL. The distribution of SHH protein and its localization with respect to a variety of cell-specific markers as ...
... Lee et al., 1997; Ruiz i Altaba, 1998), SHH could thus act in an autocrine manner in early EGL cells. SHH secreted from Purkinje neurons could then act on oEGL cells and in cells within the PL. The distribution of SHH protein and its localization with respect to a variety of cell-specific markers as ...
Sonic hedgehog and cerebellum development
... Lee et al., 1997; Ruiz i Altaba, 1998), SHH could thus act in an autocrine manner in early EGL cells. SHH secreted from Purkinje neurons could then act on oEGL cells and in cells within the PL. The distribution of SHH protein and its localization with respect to a variety of cell-specific markers as ...
... Lee et al., 1997; Ruiz i Altaba, 1998), SHH could thus act in an autocrine manner in early EGL cells. SHH secreted from Purkinje neurons could then act on oEGL cells and in cells within the PL. The distribution of SHH protein and its localization with respect to a variety of cell-specific markers as ...
Contributions to the Understanding of the Neural Bases of
... enon, others distinguish between first-order consciousness and a meta-level of consciousness. For example, they may distinguish between consciousness and metaconsciousness [13], primary consciousness and higher-order consciousness [14], or core consciousness and extended consciousness [15]. Animals ...
... enon, others distinguish between first-order consciousness and a meta-level of consciousness. For example, they may distinguish between consciousness and metaconsciousness [13], primary consciousness and higher-order consciousness [14], or core consciousness and extended consciousness [15]. Animals ...
Phase Precession and Variable Spatial Scaling in a Periodic
... proper (Jung et al., 1994; Maurer et al., 2005), the size of grid fields (and the spacing between fields) increases in cells recorded more ventrally in the MEC (Brun et al., 2008). In a CANN model, the spatial period of grid fields is a function of the mapping of the speed of the rat onto the speed of ...
... proper (Jung et al., 1994; Maurer et al., 2005), the size of grid fields (and the spacing between fields) increases in cells recorded more ventrally in the MEC (Brun et al., 2008). In a CANN model, the spatial period of grid fields is a function of the mapping of the speed of the rat onto the speed of ...
extracellular and intracellular signaling for neuronal polarity
... culture conditions and is precisely regulated by environmental cues such as secreted factors, the extracellular matrix (ECM), and neighboring cells (83, 143). Immature neurons develop within a heterogeneous environment that also contains secreted factors, the ECM, radial glial cells, and other neuro ...
... culture conditions and is precisely regulated by environmental cues such as secreted factors, the extracellular matrix (ECM), and neighboring cells (83, 143). Immature neurons develop within a heterogeneous environment that also contains secreted factors, the ECM, radial glial cells, and other neuro ...
Genesis and Control of the Respiratory Rhythm in Adult
... in vivo in adults and subsequently in vitro in neonates. In vitro data have suggested that the pacemaker neurons are the kernel of the respiratory network. These data are reviewed, and their relevance to adults is discussed. everal billion mammals, including people, manage to stay alive by breathing ...
... in vivo in adults and subsequently in vitro in neonates. In vitro data have suggested that the pacemaker neurons are the kernel of the respiratory network. These data are reviewed, and their relevance to adults is discussed. everal billion mammals, including people, manage to stay alive by breathing ...
spinal cord
... following brain regions: medulla oblongata, pons, midbrain, cerebellum, thalamus, epithalamus, hypothalamus, and cerebrum 6. Describe the specific functions of the brain regions associated with language, speech, emotions, memory, and learning 7. Explain the possible role of long-term potentiation in ...
... following brain regions: medulla oblongata, pons, midbrain, cerebellum, thalamus, epithalamus, hypothalamus, and cerebrum 6. Describe the specific functions of the brain regions associated with language, speech, emotions, memory, and learning 7. Explain the possible role of long-term potentiation in ...
Erin Hardie
... space occupying lesion develops in the brain or orbits, it presses on the neural tissue causing mechanical damage to its contents (2). There are many types of lesions that can cause similar ocular presentations to our patient such as optic nerve gliomas, pituitary adenomas, aneurysms, and a variety ...
... space occupying lesion develops in the brain or orbits, it presses on the neural tissue causing mechanical damage to its contents (2). There are many types of lesions that can cause similar ocular presentations to our patient such as optic nerve gliomas, pituitary adenomas, aneurysms, and a variety ...
Document
... Immediate memory- recall for a few seconds. Short-term memory- temporary ability to recall. Long-term memory- more permanent. Memory consolidation. ...
... Immediate memory- recall for a few seconds. Short-term memory- temporary ability to recall. Long-term memory- more permanent. Memory consolidation. ...
Chapter 14:The Brain and Cranial Nerves
... • The human brain is complex • Brain function is associated with life • This chapter is a study of brain and cranial nerves directly connected to it • Will provide insight into brain circuitry and function ...
... • The human brain is complex • Brain function is associated with life • This chapter is a study of brain and cranial nerves directly connected to it • Will provide insight into brain circuitry and function ...
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... the traditional “integrate-and-fire” model. A network of neurons with these properties interacting through synaptic receptors with many time scales can produce complex patterns of activity that cannot be intuitively predicted. Computational methods, tightly linked to experimental data, provide insig ...
... the traditional “integrate-and-fire” model. A network of neurons with these properties interacting through synaptic receptors with many time scales can produce complex patterns of activity that cannot be intuitively predicted. Computational methods, tightly linked to experimental data, provide insig ...
Comparison of nerve cord development
... some striking similarities in brain and nerve cord development shared between insects and vertebrates have already been outlined (Holland et al., 1992; Thor, 1995; Arendt and NüblerJung, 1996; D’Alassio and Frasch, 1996; Weiss et al., 1998). The rapidly growing amount of data now allows considerable ...
... some striking similarities in brain and nerve cord development shared between insects and vertebrates have already been outlined (Holland et al., 1992; Thor, 1995; Arendt and NüblerJung, 1996; D’Alassio and Frasch, 1996; Weiss et al., 1998). The rapidly growing amount of data now allows considerable ...
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... fate and give rise to a P-like descendant pattern. To distinguish this result from fate changes of a purely pathological nature, the term “transfating” was introduced to describe instances in which a cell is experimentally induced to assume the fate of a different cell. These findings were explained ...
... fate and give rise to a P-like descendant pattern. To distinguish this result from fate changes of a purely pathological nature, the term “transfating” was introduced to describe instances in which a cell is experimentally induced to assume the fate of a different cell. These findings were explained ...
Univerzita Karlova v Praze Přírodovědecká fakulta
... exposure increase the ratio of glutamate-1 receptors (GluR1) and on neurons which have low number of GluR2 was observed a slow redistribution of AMPA receptors. According to study of Chao et al. (2002), the expression of AMPA receptors depends on activation of dopamine D1 receptors and protein kinas ...
... exposure increase the ratio of glutamate-1 receptors (GluR1) and on neurons which have low number of GluR2 was observed a slow redistribution of AMPA receptors. According to study of Chao et al. (2002), the expression of AMPA receptors depends on activation of dopamine D1 receptors and protein kinas ...