Synaptic and extrasynaptic traces of long-term memory
... ago, they only need to contain unique identifiers of various entities, and that this can be achieved using relatively small molecules, using a random code (‘ID molecules’). In this paper, the logistics of information flow are followed through the steps of storage and retrieval, and the conclusion re ...
... ago, they only need to contain unique identifiers of various entities, and that this can be achieved using relatively small molecules, using a random code (‘ID molecules’). In this paper, the logistics of information flow are followed through the steps of storage and retrieval, and the conclusion re ...
Nogo Receptor mRNA Expression in Intact and Regenerating CNS
... cits. Some types of CNS neuron can, however, regenerate axons into segments of peripheral nerve grafted into the brain or spinal cord (Aguayo, 1985), but whereas all types of neuron with axons in peripheral nerve trunks can apparently regenerate, CNS neurons show large variations in their propensiti ...
... cits. Some types of CNS neuron can, however, regenerate axons into segments of peripheral nerve grafted into the brain or spinal cord (Aguayo, 1985), but whereas all types of neuron with axons in peripheral nerve trunks can apparently regenerate, CNS neurons show large variations in their propensiti ...
phys Learning Objectives Chapter 5 [10-31
... Selectively block one channel at a time – sodium blocked by tetrodotoxin applied to exterior of nerve fiber; potassium blocked by tetraethlaminonium ion applied to interior of nerve fiber 14. Describe the events that occur to cause an action potential: Before the potential starts, the conductance of ...
... Selectively block one channel at a time – sodium blocked by tetrodotoxin applied to exterior of nerve fiber; potassium blocked by tetraethlaminonium ion applied to interior of nerve fiber 14. Describe the events that occur to cause an action potential: Before the potential starts, the conductance of ...
Multimodal Integration in Rostral Fastigial Nucleus Provides an
... signals underlies the accurate computation of body motion. Furthermore, the same neurons that encode body motion (i.e., bimodal neurons) most likely encode vestibular signals in a body-referenced coordinate frame, since the integration of proprioceptive and vestibular information is required for bot ...
... signals underlies the accurate computation of body motion. Furthermore, the same neurons that encode body motion (i.e., bimodal neurons) most likely encode vestibular signals in a body-referenced coordinate frame, since the integration of proprioceptive and vestibular information is required for bot ...
Papazian Lab Homepage Electrical excitability in the brain
... Lin, M.A., Abramson, J., and Papazian, D.M. (2009) Transfer of ion binding site from ether-à-go-go to Shaker: Mg2+ binds to resting state to modulate channel opening. Submitted for publication. Figueroa, K.P.*, Minassian, N.A.*, Stevanin G., Waters, M., Garibyan, V., Bürk, K., Brice, A., Dürr, A., ...
... Lin, M.A., Abramson, J., and Papazian, D.M. (2009) Transfer of ion binding site from ether-à-go-go to Shaker: Mg2+ binds to resting state to modulate channel opening. Submitted for publication. Figueroa, K.P.*, Minassian, N.A.*, Stevanin G., Waters, M., Garibyan, V., Bürk, K., Brice, A., Dürr, A., ...
Wang et al 2photon calcium imaging of odor in fly brain cell 2003
... response to odors are revealed by these initial experiments. Different odors elicit different patterns of glomerular activation and these patterns are conserved among different animals. At odor concentrations likely to be encountered in nature, the map is sparse and glomeruli are narrowly tuned. The ...
... response to odors are revealed by these initial experiments. Different odors elicit different patterns of glomerular activation and these patterns are conserved among different animals. At odor concentrations likely to be encountered in nature, the map is sparse and glomeruli are narrowly tuned. The ...
Mouse Nerve Growth Factor Prevents Degeneration of Axotomized
... 1986). Prior to use, NGF was passed through a 0.2~pm filter (Uniflo, Schleicher and Schuell, Keene, NH) and stored at 200 &ml in 0.2% acetic acid at - 70°C. NGF was lyophilized and resuspended in acidified cerebrospinal fluid (CSF, see below) immediately prior to the intraventricular injection. Foll ...
... 1986). Prior to use, NGF was passed through a 0.2~pm filter (Uniflo, Schleicher and Schuell, Keene, NH) and stored at 200 &ml in 0.2% acetic acid at - 70°C. NGF was lyophilized and resuspended in acidified cerebrospinal fluid (CSF, see below) immediately prior to the intraventricular injection. Foll ...
Proopiomelanocortin Neurons in Nucleus Tractus Solitarius Are
... (1) short absolute latency (1–10 ms), (2) minimal synaptic jitter, the SD of the intraneuronal latency (⬍200 s), and (3) the absence of synaptic failures at high stimulus frequencies (50 –100 Hz) to a burst of five shocks. Successive shocks (train of five pulses at 50 Hz) evoked a frequency-depende ...
... (1) short absolute latency (1–10 ms), (2) minimal synaptic jitter, the SD of the intraneuronal latency (⬍200 s), and (3) the absence of synaptic failures at high stimulus frequencies (50 –100 Hz) to a burst of five shocks. Successive shocks (train of five pulses at 50 Hz) evoked a frequency-depende ...
MECHANISMS OF VERTEBRATE SYNAPTOGENESIS
... synaptic vesicles carrying neurotransmitter molecules. A depolarizing action potential invading the bouton causes synaptic vesicles docked at the plasma membrane to fuse and release their neurotransmitter into the synaptic cleft, a small space between the pre- and postsynaptic cells. Synaptic vesicl ...
... synaptic vesicles carrying neurotransmitter molecules. A depolarizing action potential invading the bouton causes synaptic vesicles docked at the plasma membrane to fuse and release their neurotransmitter into the synaptic cleft, a small space between the pre- and postsynaptic cells. Synaptic vesicl ...
PDF file
... from the field of view randomly, but rather, they move continuously across the field of view, given their motion is not too fast for the brain to respond. At the pixel level, views are very discontinuous as image patches sweep across the field of view. Motivated by cerebral cortex, our model explore ...
... from the field of view randomly, but rather, they move continuously across the field of view, given their motion is not too fast for the brain to respond. At the pixel level, views are very discontinuous as image patches sweep across the field of view. Motivated by cerebral cortex, our model explore ...
Antennal Mechanosensory Neurons Mediate Wing Motor Reflexes
... expression in individual flies, we inspected each fly’s brain after the experiment using a 2-photon microscope and confirmed that EGFPlabeled JO neurons are not present, but EGFP signal could be detected in other central neurons driven by the JO-AB/JO-CE GAL4 driver. In these experiments, the progen ...
... expression in individual flies, we inspected each fly’s brain after the experiment using a 2-photon microscope and confirmed that EGFPlabeled JO neurons are not present, but EGFP signal could be detected in other central neurons driven by the JO-AB/JO-CE GAL4 driver. In these experiments, the progen ...
Acid – Base Physiology
... Reabsorbed into the circulation Note; this process is all driven by the active transcellular movement of Na+ ...
... Reabsorbed into the circulation Note; this process is all driven by the active transcellular movement of Na+ ...
Dopamine is produced in the rat spinal cord and regulates
... et al., 2012), indicating that DA in regions other than the brain may modulate micturition. Recent studies revealed that autonomic neurons in the rat lower spinal cord express DA receptors (Gladwell et al., 1999; Stafford and Coote, 2006), suggesting that DA released within the cord helps regulate a ...
... et al., 2012), indicating that DA in regions other than the brain may modulate micturition. Recent studies revealed that autonomic neurons in the rat lower spinal cord express DA receptors (Gladwell et al., 1999; Stafford and Coote, 2006), suggesting that DA released within the cord helps regulate a ...
Approximating Number of Hidden layer neurons in Multiple
... number of neurons that should be kept in the hidden layer so that the neural network training time can be reduced and also accuracy in determining target output can be increased. Basically when dealing with the number of neurons in the input layer, one has to analyze about the data which is trained. ...
... number of neurons that should be kept in the hidden layer so that the neural network training time can be reduced and also accuracy in determining target output can be increased. Basically when dealing with the number of neurons in the input layer, one has to analyze about the data which is trained. ...
Article PDF
... tissue sections. AP expression in cell bodies and processes usually allowed identification of most labeled cells as neurons or glia. Cortical cell types were frequently discernible in AP-stained sections according to standard morphological criteria (for review, see Peters and Jones, 1984). The pyram ...
... tissue sections. AP expression in cell bodies and processes usually allowed identification of most labeled cells as neurons or glia. Cortical cell types were frequently discernible in AP-stained sections according to standard morphological criteria (for review, see Peters and Jones, 1984). The pyram ...
Brain Stem Involvement in Immune and Aversive Challenge Jakob Paues
... prostaglandins, which in turn can interact with the central nervous system (CNS) to affect behaviour. The CNS also memorises substances that have made us sick in the past to avoid future harm, a phenomenon called conditioned taste aversion (CTA). An often used model to study CTA is the intraperitone ...
... prostaglandins, which in turn can interact with the central nervous system (CNS) to affect behaviour. The CNS also memorises substances that have made us sick in the past to avoid future harm, a phenomenon called conditioned taste aversion (CTA). An often used model to study CTA is the intraperitone ...
- Columbia University Medical Center
... are also expressed by proprioceptive sensory neurons, raising the possibility that cadherins regulate additional steps in the development of sensory-motor circuits. Introduction Many hundreds of neuronal cell types are generated during the development of the vertebrate central nervous system (CNS)—a ...
... are also expressed by proprioceptive sensory neurons, raising the possibility that cadherins regulate additional steps in the development of sensory-motor circuits. Introduction Many hundreds of neuronal cell types are generated during the development of the vertebrate central nervous system (CNS)—a ...
07.11 - UCSD Cognitive Science
... tracer was injected at multiple sites within the face, arm, or leg representation of M1. In seven animals, we injected the McIntyre-B strain of HSV1 (supplied by Dr. David Bernstein, Gamble Institute of Medical Research, C incinnati, OH) (McC lean et al., 1989). In one animal, we injected a strain o ...
... tracer was injected at multiple sites within the face, arm, or leg representation of M1. In seven animals, we injected the McIntyre-B strain of HSV1 (supplied by Dr. David Bernstein, Gamble Institute of Medical Research, C incinnati, OH) (McC lean et al., 1989). In one animal, we injected a strain o ...
judasMRT99
... In the developing neocortex of rats and mice, nitrinergic neurons are usually not observed in the marginal zone (MZ), i.e., the developing layer I (Bravo et al., 1997; Derer and Derer, 1993; Iwase et al., 1998; Tomić et al., 1994; Van Eden et al., 1996); they were also not observed in the neocortex ...
... In the developing neocortex of rats and mice, nitrinergic neurons are usually not observed in the marginal zone (MZ), i.e., the developing layer I (Bravo et al., 1997; Derer and Derer, 1993; Iwase et al., 1998; Tomić et al., 1994; Van Eden et al., 1996); they were also not observed in the neocortex ...
disparity detection from stereo
... correspondence problem have been explored using area-based, feature-based, pixel-based, and phase-based as well as Bayesian approaches [8]. While those approaches have obtained limited success in special problems, it is becoming increasingly clear that they are not robust against wide variations in ...
... correspondence problem have been explored using area-based, feature-based, pixel-based, and phase-based as well as Bayesian approaches [8]. While those approaches have obtained limited success in special problems, it is becoming increasingly clear that they are not robust against wide variations in ...
Representation of Behavioral Tactics and Tactics
... cue onset, epoch 2 beginning 150 ms before Figure 4. A–C, Tactics-selective activity of a pmPFC neuron preferentially observed during the delay and response period of and ending 150 ms after the hold release, and tactics-only cued trials. Data plots and display formats are the same as in Figure 3. C ...
... cue onset, epoch 2 beginning 150 ms before Figure 4. A–C, Tactics-selective activity of a pmPFC neuron preferentially observed during the delay and response period of and ending 150 ms after the hold release, and tactics-only cued trials. Data plots and display formats are the same as in Figure 3. C ...
From/To LTM - Ohio University
... Spatio-temporal memories are fundamental to self-organization and learning in bio-inspired systems. Short term memory (STM) and long term memory (LTM): two major types of memories in neurobiological research of human brain. They occupy different regions of the human brain, have different structu ...
... Spatio-temporal memories are fundamental to self-organization and learning in bio-inspired systems. Short term memory (STM) and long term memory (LTM): two major types of memories in neurobiological research of human brain. They occupy different regions of the human brain, have different structu ...
Interspike Intervals, Receptive Fields, and Information Encoding in
... independent from another much-debated question in cortical physiology: whether cortical neurons encode information through a rate code or a temporal code. In fact, both types of code can generate receptive-field maps and information rates similar to what is described here. However, the existence of ...
... independent from another much-debated question in cortical physiology: whether cortical neurons encode information through a rate code or a temporal code. In fact, both types of code can generate receptive-field maps and information rates similar to what is described here. However, the existence of ...
Pre-Bötzinger complex
The pre-Bötzinger complex (preBötC) is a cluster of interneurons in the ventrolateral medulla of the brainstem. This complex has been proven to be essential for the generation of respiratory rhythm in mammals. The exact mechanism of the rhythm generation and transmission to motor nuclei remains controversial and the topic of much present research.Several synthetic compounds have been shown to act on neurons specific to the preBötC, most being selective agonists or antagonists to receptor subtypes on neurons in the vicinity. Since many of these neurons express GABA, glutamate, serotonin and adenosine receptors, chemicals custom tailored to bind at these sites are most effective at altering respiratory rhythm.Adenosine modulates the preBötC output via activation of the A1 and A2A receptor subtypes. An adenosine A1 receptor agonist has been shown to depress preBötC rhythmogenesis independent of the neurotransmitters GABA and glycine in ""in vitro"" preparations from 0-7 day old mice. Another synthetic drug specific to the adenosine A2A receptor subtype is CGS-21680 that has been shown to cause apneas in 14-21 day old rat pups in vivo. For this reason, it has been used as a model to study pathological conditions such as apnea of prematurity and SIDS in neonatal infants.