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166 - UCSF Physiology - University of California, San Francisco
166 - UCSF Physiology - University of California, San Francisco

... locations between neuronal axons and dendrites. On the presynaptic side, it depends on the proper assembly of different synaptic vesicle pools at the active zone (Rosenmund and Stevens, 1996; Schneggenburger et al., 1999; Wu and Borst, 1999; Schikorski and Stevens, 2001; Mozhayeva et al., 2002; Tasc ...
Correlation between auditory threshold and the auditory brainstem
Correlation between auditory threshold and the auditory brainstem

... infections, hyperbilirubinemia, meningitis, fetal distress and perinatal asphyxia. The early detection of this hearing loss can be diagnostic with sensitive techniques, such as the auditory brainstem response (ABR). These techniques are the relatively early component of the auditory evoked potential ...
Brain and effort: brain activation and effort-related working
Brain and effort: brain activation and effort-related working

... In addition to functional differences between KLS and controls, we have also observed that the level of activation differs between individuals with low and high working memory capacity. In a study involving young, healthy participants, performance on the reading span task (administered during a neur ...
On the importance of the transient visual response in the superior
On the importance of the transient visual response in the superior

... orienting network that have been identified and reviewed in detail elsewhere [6,7,11,12–15]. The SC is a critical hub in this circuit. It is a multi-layered structure (Figure 2a) that can be separated functionally into superficial, visual-only layers (SCs), and intermediate and deep layers (SCi) r ...
Effects of galanin on wide-dynamic range neuron activity
Effects of galanin on wide-dynamic range neuron activity

... of 0.9% saline as control group; –d–: galantide 1 nmol. Data are presented as mean 1 S.E.M. The statistical difference between groups was evaluated by two-way analysis of variance (ANOVA), ***P , 0.001 compared with the control group. ...
Behavioral dopamine signals
Behavioral dopamine signals

... In general terms, prediction errors might contribute to the self-organization of behavior. Brain mechanisms establish predictions, compare current inputs with predictions from previous experience and emit a prediction-error signal if a mismatch is detected. The error signal might function as an impu ...
Chapter 12 - Las Positas College
Chapter 12 - Las Positas College

...  Cover the axon in a tightly packed coil of ...
Action-based language: A theory of language acquisition
Action-based language: A theory of language acquisition

... judged the sensibility of sentences describing the transfer of concrete objects such as “Andy delivered the pizza to you/You delivered the pizza to Andy” and abstract information, such as “Liz told you the story/You told Liz the story”. As in these examples, half of the sensible sentences described ...
EUGENE GARFIELD
EUGENE GARFIELD

... not. The reviewer needs to outline the directions that are likely to be most productive for the next round of research-directions that are both interesting and doable— and to explain these directions clearly to the reader. A good review is particularly worthwhile and important in newly emerging area ...
the distribution of the cells of origin of callosal projections in cat
the distribution of the cells of origin of callosal projections in cat

MR-guided parenchymal delivery of adeno-associated
MR-guided parenchymal delivery of adeno-associated

... colleagues recently described how vector titer could affect vector distribution. In their experience, identical volumes with different vector concentration revealed a positive direct correlation between high titers and large distribution pattern of protein expression.29 In the present study, thalami ...
Cerebellum. - Department of Physiology
Cerebellum. - Department of Physiology

... by a group of cells in CN that connect reciprocally with an Output Population (OP) of neurons in another part of the brain. State transitions of the attractor network, eg. from relative quiescence to intense activity, can be initiated by one of the Diverse Inputs to the OP, under the regulatory infl ...
reviews - Center for Complex Systems and Brain Sciences
reviews - Center for Complex Systems and Brain Sciences

ficient mice: Distinct effects in Finnish variant late infantile NCL
ficient mice: Distinct effects in Finnish variant late infantile NCL

... nia and seizures culminating in an early death between 14 and 36 years (Santavuori et al., 1993; Santavuori et al., 1982). Although the function of the CLN5 protein has remained elusive, the consensus view is that its predominant form is a soluble lysosomal protein (Sleat et al., 2005). Several anim ...
Rearrangement of microtubule polarity orientation during conversion
Rearrangement of microtubule polarity orientation during conversion

Contextual Modulation of Substantia Nigra Pars Reticulata Neurons
Contextual Modulation of Substantia Nigra Pars Reticulata Neurons

... and modulations were absent for spontaneous saccades. These results and other recent work on the basal ganglia suggest that some saccaderelated signals in the SNr may be influenced by the reinforcement associated with a particular saccadic eye movement. ...
The Evolution of Neuron Types and Cortical
The Evolution of Neuron Types and Cortical

... comparative neuroanatomy. This book argued for the predictability of neuroanatomical structure from brain size and encephalization, suggesting that these metrics form the most significant contribution to species diversity in brain organization. Combined with the ready availability of comparative bra ...
Representation of Movement
Representation of Movement

... to move smoothly and continuously but rather suddenly jump to a new location. Further, the condition is only associated with deficits in motion processing, without changes in acuity or localization abilities. A number of fundamental psychophysical observations are critical for understanding the phys ...
Neurodynamical modeling of arbitrary visuomotor tasks
Neurodynamical modeling of arbitrary visuomotor tasks

... This thesis consists of an introductory chapter and publications by the doctoral student, which are printed in the chapters thereafter. In the introductory section, we give first a review of the literature of conditional visuomotor learning. We focus on the specific experiments used to study this pa ...
Lin J, 2013 - Tsien lab Website - University of California San Diego
Lin J, 2013 - Tsien lab Website - University of California San Diego

... We used ReaChR expressed in the vibrissa motor cortex to drive spiking and vibrissa motion in awake mice when excited with red light through intact skull. Precise vibrissa movements were evoked by expressing ReaChR in the facial motor nucleus in the brainstem and illumination with red light through ...
Clustered Organization of Neurons with Similar Extra
Clustered Organization of Neurons with Similar Extra

... five different penetrations. The summation indices of all neurons recorded were shown (Figure 3, left panels), together with histological reconstruction of the electrode track through the cortical layers (Figure 3, right panels). Regardless of whether the penetration was tangential, oblique, or norm ...
pdf
pdf

... expected high regional representational similarity for comparisons of the same association, and low similarity for comparisons of different associations, yielding a conjunctiveness metric for each voxel. Specific comparisons were excluded to penalize perceptually driven effects (striped/blank cells): ...
Auditory Neurons in the Dorsal Cortex of the Inferior Colliculus
Auditory Neurons in the Dorsal Cortex of the Inferior Colliculus

... the auditory nerve. The cochlear nucleus is subdivided into ventral and dorsal divisions (VCN and DCN, respectively). The ventral division can be further subdivided into the anterior ventral cochlear nucleus (AVCN), and the posterior ventral cochlear nucleus (PVCN). Each division of the CN receives ...
Kiecker and Lumsden - McLoon Lab
Kiecker and Lumsden - McLoon Lab

... Ventral Patterning in the Hindbrain and Midbrain Early in its development, the hindbrain becomes subdivided into a series of seven to eight segments called rhombomeres (r1–8) (reviewed in Kiecker & Lumsden 2005). Nevertheless, the topological organization of neurons along the DV axis of the hindbrai ...
NMDA receptor blockade causes selective prefrontal
NMDA receptor blockade causes selective prefrontal

... not peer-reviewed) is the author/funder. It is made available under a CC-BY-NC 4.0 International license. ...
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Nervous system network models

Network of human nervous system comprises nodes (for example, neurons) that are connected by links (for example, synapses). The connectivity may be viewed anatomically, functionally, or electrophysiologically. These are presented in several Wikipedia articles that include Connectionism (a.k.a. Parallel Distributed Processing (PDP)), Biological neural network, Artificial neural network (a.k.a. Neural network), Computational neuroscience, as well as in several books by Ascoli, G. A. (2002), Sterratt, D., Graham, B., Gillies, A., & Willshaw, D. (2011), Gerstner, W., & Kistler, W. (2002), and Rumelhart, J. L., McClelland, J. L., and PDP Research Group (1986) among others. The focus of this article is a comprehensive view of modeling a neural network (technically neuronal network based on neuron model). Once an approach based on the perspective and connectivity is chosen, the models are developed at microscopic (ion and neuron), mesoscopic (functional or population), or macroscopic (system) levels. Computational modeling refers to models that are developed using computing tools.
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