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Form representation in monkey inferotemporal cortex is virtually
Form representation in monkey inferotemporal cortex is virtually

... retina, often in a task that does not require stimulus identification (for example, refs. 3–7). It is not clear if neuronal activity would differ in conditions that more closely approximate the animal’s natural behavior. During natural visual exploration (that is, ‘active vision’8), animals are moti ...
CELL MIGRATION IN THE FOREBRAIN
CELL MIGRATION IN THE FOREBRAIN

... Key Words radial, tangential, interneuron, pyramidal neuron, telencephalon ■ Abstract The forebrain comprises an intricate set of structures that are required for some of the most complex and evolved functions of the mammalian brain. As a reflection of its complexity, cell migration in the forebrain ...
Visual Processing in the Primate Brain
Visual Processing in the Primate Brain

... evolved biological system, the goal of vision is not to produce a veridical description of the external world but a description that facilitates adaptive behavior. Those aspects of the input that contain information critical for behavior will be emphasized and those aspects that carry little informa ...
Separate Representations of Target and Timing Cue Locations in
Separate Representations of Target and Timing Cue Locations in

... stimulus that encodes the target position and also encode the information available from the timing cue. This could pose a challenge to the oculomotor system since the representation of the timing stimulus location in one brain area might be interpreted by downstream neurons as a competing motor pla ...
Models and Measurements of Functional Maps in V1
Models and Measurements of Functional Maps in V1

... that temporal frequency tuning also be represented to predict distributed cortical activity patterns (Figs. 2 and 3). According to the spatiotemporal filtering model, a unified description of the organization of V1 consists of several maps of filter properties: orientation preference, SF preference, ...
Predominance of Movement Speed Over Direction in Neuronal
Predominance of Movement Speed Over Direction in Neuronal

... such as reflected in the intracranial EEG (iEEG). We show that in iEEG, contrasting to what has been previously found on the single neuron level, speed predominates over velocity. The predominant speed representation was present in nearly all iEEG signal features, up to the 600–1000 Hz range. Using a ...
Discrete coding of stimulus value, reward expectation, and reward
Discrete coding of stimulus value, reward expectation, and reward

... recorded in at least 7 trials for each probability condition, and in this study it was subjected to further ...
D2 receptor overexpression in the striatum leads to a deficit in
D2 receptor overexpression in the striatum leads to a deficit in

... SKF-81297 on the evoked IPSC and EPSC trains in both transgenic and control mice. SKF-81297 is a highly D1-selective agonist, which has a Ki for the D1 receptor of ∼2 nM but has a Ki for the D2R of ∼1,000 nM (24). We and others recently reported that SKF-81297 at a concentration of 1 μM significantly ...
Pallidal Origin of GABA Release within the Substantia Nigra Pars
Pallidal Origin of GABA Release within the Substantia Nigra Pars

... High-frequency stimulation of the subthalamic nucleus (HFS-STN) is an effective treatment for alleviating the motor symptoms of parkinsonian patients. However, the neurochemical basis of its effects remains unknown. We showed previously that 1 h of HFS-STN in normal rats increases extracellular glut ...
MDD_DMN_DFC_manuscript_revised_2_Final
MDD_DMN_DFC_manuscript_revised_2_Final

... Sliding window analysis was performed using custom Python (https://www.python.org/) scripts. Data were split into 40 second Gaussian moving windows, staggered by one TR, created using a Gaussian kernel with a standard deviation of 8 seconds (see supplementary methods for a detailed discussion of the ...
Predominance of Movement Speed Over Direction in Neuronal
Predominance of Movement Speed Over Direction in Neuronal

... such as reflected in the intracranial EEG (iEEG). We show that in iEEG, contrasting to what has been previously found on the single neuron level, speed predominates over velocity. The predominant speed representation was present in nearly all iEEG signal features, up to the 600–1000 Hz range. Using a ...
Differential innervation of superficial versus deep - HAL
Differential innervation of superficial versus deep - HAL

... Convergent data showed that bulbo-spinal serotonergic projections exert complex modulatory influences on nociceptive signaling within the dorsal horn. These neurons are located in the B3 area which comprises the median raphe magnus (RMg) and the lateral paragigantocellular reticular (LPGi) nuclei. Be ...
Carlsson J Neurosci 2007 (pdf 2,2 MB)
Carlsson J Neurosci 2007 (pdf 2,2 MB)

... illustrated in Figure 1 B. To obtain a cell suspension rich in DA neuroblasts but with as few serotonin cells as possible, the rostral cut was placed so as to include part of the caudal diencephalon. Then, a midline cut was performed through the tectum, and the tissue was folded open so that the ins ...
Generation of Theta and Gamma Rhythms in the Hippocampus
Generation of Theta and Gamma Rhythms in the Hippocampus

... LEUNG, L. S. Generation of theta and gamma rhythms in the hippocampus. NEUROSCI BIOBEHAV REV 22(2), 275–290, 1998.—In the behaving rat, theta rhythm was dominant during walking and rapid-eye-movement sleep, while irregular slow activity predominated during immobility and slow-wave sleep. Oscillatory ...
Dopamine`s Actions in Primate Prefrontal Cortex
Dopamine`s Actions in Primate Prefrontal Cortex

... association memories that arise from sequence repetitions. In these more classic forms of plasticity, experiences are stored as architectural changes in synapses, e.g., with the formation of new spines or structural changes in existing immature spines, as documented in the sensory cortices, hippocam ...
Slides - Translational Neuromodeling Unit
Slides - Translational Neuromodeling Unit

Neural crest cells and axonal specificity
Neural crest cells and axonal specificity

... pluripotency. A single neural crest cell can differentiate into any of several different cell types, depending on its location within the embryo. For example, the parasympathetic neurons formed by the vagal (neck) neural crest cells produce acetylcholine as their neurotransmitter; they are therefore ...
Nerve Growth Factor and Alzheimer`s Disease
Nerve Growth Factor and Alzheimer`s Disease

... It has been considered that the high-affinity of TrkA is guaranteed by the interaction with p75, because TrkA and p75 are coexpressed in particular neurons. However, p75 is structurally belong to the tumor necrosis factor (TNF) receptor family, and has been shown to mediate cell death signals as si ...
2nd year - FORTH-ICS - Foundation for Research and Technology
2nd year - FORTH-ICS - Foundation for Research and Technology

... within the cortex, as suggested by our preliminary results. A major implication of this, both for biological and for artificial agents, is that it should be possible to train their motor system by simple action-observation and action-recall. The representations, shared by both overt actions and by m ...
2011-Morrison and Nakamura_review
2011-Morrison and Nakamura_review

... thermosensory ascending pathway from lamina I neurons is the spinothalamocortical pathway, in which lamina I neurons directly synapse on neurons in the thalamus that project to the primary somatosensory cortex, leading to perception and discrimination of cutaneous temperature (25,26). However, the s ...
- Wiley Online Library
- Wiley Online Library

... every fMRI study. Using a comprehensive set of regions of interest positioned throughout the brain, Power et al. (2012) showed that seed-based correlation maps of functional resting-state connectivity are vulnerable to head displacement and rotation. Importantly, their study suggested that residual ...
The polyvagal theory: phylogenetic substrates of a
The polyvagal theory: phylogenetic substrates of a

... react to challenge in order to maintain visceral homeostasis. These reactions change physiological state and, in mammals, limit sensory awareness, motor behaviors, and cognitive potentials. We can intuitively grasp the limitations of behavior when described in terms such as dexterity, speed and stre ...
The polyvagal theory: phylogenetic substrates of
The polyvagal theory: phylogenetic substrates of

... react to challenge in order to maintain visceral homeostasis. These reactions change physiological state and, in mammals, limit sensory awareness, motor behaviors, and cognitive potentials. We can intuitively grasp the limitations of behavior when described in terms such as dexterity, speed and stre ...
Neuronal activity in human primary visual cortex correlates with
Neuronal activity in human primary visual cortex correlates with

... rivalry? For comparison, we did a separate series of scans measuring V1 activity while the stimuli physically alternated between the two monocular gratings (Fig. 1c). The duration of each stimulus presentation was determined by randomly sampling from the distribution of durations reported (via the s ...
Human Economic Choice as Costly Information Processing
Human Economic Choice as Costly Information Processing

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Nervous system network models

Network of human nervous system comprises nodes (for example, neurons) that are connected by links (for example, synapses). The connectivity may be viewed anatomically, functionally, or electrophysiologically. These are presented in several Wikipedia articles that include Connectionism (a.k.a. Parallel Distributed Processing (PDP)), Biological neural network, Artificial neural network (a.k.a. Neural network), Computational neuroscience, as well as in several books by Ascoli, G. A. (2002), Sterratt, D., Graham, B., Gillies, A., & Willshaw, D. (2011), Gerstner, W., & Kistler, W. (2002), and Rumelhart, J. L., McClelland, J. L., and PDP Research Group (1986) among others. The focus of this article is a comprehensive view of modeling a neural network (technically neuronal network based on neuron model). Once an approach based on the perspective and connectivity is chosen, the models are developed at microscopic (ion and neuron), mesoscopic (functional or population), or macroscopic (system) levels. Computational modeling refers to models that are developed using computing tools.
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