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The Biology
The Biology

... Because it evolved very early, the [a] _______________ of the brain is referred to as the old brain. It is composed of the medulla, which controls functions like breathing and heartbeat; the pons, which transmits information helping to coordinate muscle activity on the right and left halves of the b ...
Mirror neuron functioning: an explanation for
Mirror neuron functioning: an explanation for

... own. During this action and action-observation two areas were found in which overlap in activity was present; the inferior frontal cortex and rostal-most region of the right superior parietal lobe. This overlap in activity could indicate that neurons in those areas were firing in both conditions and ...
5104-c2
5104-c2

... lack of understanding of how these single-cell oscillators are coupled. The new study3 demonstrates that SCN neurons are coupled through direct electrical connections. This coupling is lost in mice deficient in Cx36. Bottom, schematics of wheel-running activity records from WT and Cx36-deficient mic ...
Day 3 - EE Sharif
Day 3 - EE Sharif

... When the cell membranes are stimulated, there is a change in the permeability of the membrane to sodium ions (Na+). The membrane becomes more permeable to Na+ and K+, therefore sodium ions diffuse into the cell down a concentration gradient. The entry of Na+ disturbs the resting potential and causes ...
Inhibition of central neurons is reduced following acoustic trauma
Inhibition of central neurons is reduced following acoustic trauma

... The most common tail response (class A, Fig. 2E) consists of broadly-tuned excitatory responses at and below an upper cutoff frequency (22 kHz in Fig. 2E). The upper frequency edge of the response is sharp at all levels with inhibition sometimes visible at higher frequencies. Auditory nerve fibers i ...
Olfactory System and Olfaction (Molitor): Worksheet Stephanie Lee
Olfactory System and Olfaction (Molitor): Worksheet Stephanie Lee

... Olfactory stem cells reside near laminar surface of epithelium and serve as ORN ______________ Other olfactory neurons within CNS also regenerate Olfactory stem cells – replacement for damaged neurons? ...
FIGURE LEGENDS FIGURE 39.1 Locomotor activity rhythm of a
FIGURE LEGENDS FIGURE 39.1 Locomotor activity rhythm of a

... revolutions. Wheel revolutions are then plotted versus time, for weeks of data. Each horizontal line represents 48 hours of data. Wheel revolutions appear as bars coming up fromthe baseline, with their height proportional to the number of revolutions. On the first line of the record, the first 48 ho ...
Neural Correlates for Perception of 3D Surface Orientation from
Neural Correlates for Perception of 3D Surface Orientation from

... of mitochondria in unc-84(n369) was normal (Fig. 4C), suggesting that ANC-1 does not require UNC-84 to anchor mitochondria as it does for nuclear anchorage. Our model (fig. S4) suggests that ANC-1 functions to anchor nuclei by tethering the nucleus to the actin cytoskeleton and predicts that the KAS ...
Dopamine Modulates the Function of Group II and Group III
Dopamine Modulates the Function of Group II and Group III

... III mGluR activation [L-(⫹)-2-amino-4-phosphonobutyric acid, L-AP4, 500 ␮M], at STN-SNr synapses is significantly decreased. This effect could be mimicked in control slices by prior bath application of haloperidol (20 ␮M) and R-(⫹)-7-chloro-8hydroxy-3-methyl-1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazep ...
Basal Ganglia
Basal Ganglia

... Recently, it has been demonstrated that some of the symptoms of Parkinson’s disease can be reduced or alleviated by stimulating implants placed in the thalamus, subthalamic nucleus or pallidum. The improvement gained from these electrical stimulating techniques depends on the location of the stimula ...
Pontine respiratory activity involved in inspiratory/expiratory phase
Pontine respiratory activity involved in inspiratory/expiratory phase

... pontine-based control of IE phase transition by both the pontine Kölliker–Fuse nucleus (KF) and parabrachial complex is seen as a secondary or backup mechanism. However, previous studies have shown that the BHR can habituate in vivo. Thus, habituation reduces sensory feedback, so the role of the po ...
The Endogenously Active Brain: The Need for an
The Endogenously Active Brain: The Need for an

... of neurons) with sensory stimuli or motor activities. With respect to visual processing, for example, researchers beginning with Kuffler [Kuffler 1953] and Hubel and Wiesel [Hubel & Wiesel 1962, 1968] employed such techniques as single- and multi-cell recording to determine what features of visual s ...
1 1 1 1 - UPM ASLab
1 1 1 1 - UPM ASLab

... REPEAT. Φ is the sum of the two – a measure of information crossing the cut ...
Emotional and Behavioral Correlates of Mediodorsal Thalamic
Emotional and Behavioral Correlates of Mediodorsal Thalamic

... two screws to serve as a ground. Two bipolar electrodes for intracranial stimulation were implanted in the medial forebrain bundle (anterior, 25.2 from bregma; lateral, 60.8; ventral, 8.2), according to the atlas of Paxinos and Watson (1986). After the cut end of the temporal muscle was covered with ...
The LIM and POU homeobox genes ttx-3 and unc
The LIM and POU homeobox genes ttx-3 and unc

... 2010). However, few neuronal transcription factors are expressed exclusively in only one specific neuronal cell type (Gray et al., 2004; Lein et al., 2007). For example, in addition to being expressed in midbrain dopaminergic neurons, Nurr1 is expressed in other nondopaminergic neuronal cell types i ...
12 - William M. Clark, M.D
12 - William M. Clark, M.D

... • Gender-specific areas appear in both brain and spinal cord, depending on presence or absence of fetal testosterone • Maternal exposure to radiation, drugs (e.g., alcohol and opiates), or infection can harm the developing CNS • Smoking decreases oxygen in the blood, which can lead to neuron death a ...
From hand actions to speech: evidence and speculations
From hand actions to speech: evidence and speculations

... “Organs  develop  to  serve  one  purpose,  and  when  they  have  reached  a  certain  form in the evolutionary process, they became available for different purposes, at which  point  the  processes  of  natural  selection  may  refine  them  further  for  these  purposes”.  This sentence comes fro ...
Analysis of Back Propagation of Neural Network Method in the
Analysis of Back Propagation of Neural Network Method in the

... systems, Learning involves adjustments to the synaptic connections that exist between the neurons. Neural networks process information in a similar way the human brain does. The network is composed of a large number of highly interconnected processing elements working in parallel to solve a specific ...
ling411-16 - Rice University
ling411-16 - Rice University

... subdivided into functional columns on the basis of additional features  That is, this columnar structure is representing categories and subcategories ...
Gust & Olfac
Gust & Olfac

... • Olfactory reception involved detecting dissolved chemicals as they interact with odorant binding proteins ...
Neural correlates of consciousness: A definition of the dorsal and
Neural correlates of consciousness: A definition of the dorsal and

... element of premotor category function. Joint position will be served by the cerebellum.The organization of cerebellar global networks parallels that of the basal ganglia [20]. The afferent limb is a massive corticopontine and mossy fibre system. The efferent reentrant limb is a projection of the dee ...
Bypassing V1: a direct geniculate input to area MT
Bypassing V1: a direct geniculate input to area MT

... of higher extrastriate cortical areas. Historically, these regions were defined as ‘higher’ because they were not thought to receive direct geniculate input. In humans, loss of V1 devastates eyesight by cutting off the flow of visual information from the LGN to extrastriate visual cortex. Curiously, ...
Brain-Derived Neurotrophic Factor Mediates Activity
Brain-Derived Neurotrophic Factor Mediates Activity

... Brain-derived neurotrophic factor (BDNF) promotes postnatal maturation of GABAergic inhibition in the cerebral and cerebellar cortices, and its expression and release are enhanced by neuronal activity, suggesting that it acts in a feedback manner to maintain a balance between excitation and inhibiti ...
Frequency-Dependent Processing in the Vibrissa Sensory System
Frequency-Dependent Processing in the Vibrissa Sensory System

... ranges of vibrissa motion, generated by rodent sensory behaviors (e.g., active exploration or resting) and by stimulus features, characterize perception by this system. During active exploration, rats typically sweep their vibrissae at ⬃4 –12 Hz against and over tactual surfaces, and during rest or ...
biological bases of behavior
biological bases of behavior

... disallowed, allowing them to go to other areas of need. Blocking Neurotransmitter receptors – This is used when amounts of neurotransmitters needs to be lowered. Mimicking Neurotransmitters – Chemicals within the drugs are so similar to neurotransmitters, they are allowed into receptor areas in the ...
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Synaptic gating



Synaptic gating is the ability of neural circuits to gate inputs by either suppressing or facilitating specific synaptic activity. Selective inhibition of certain synapses has been studied thoroughly (see Gate theory of pain), and recent studies have supported the existence of permissively gated synaptic transmission. In general, synaptic gating involves a mechanism of central control over neuronal output. It includes a sort of gatekeeper neuron, which has the ability to influence transmission of information to selected targets independently of the parts of the synapse upon which it exerts its action (see also neuromodulation).Bistable neurons have the ability to oscillate between a hyperpolarized (down state) and a depolarized (up state) resting membrane potential without firing an action potential. These neurons can thus be referred to as up/down neurons. According to one model, this ability is linked to the presence of NMDA and AMPA glutamate receptors. External stimulation of the NMDA receptors is responsible for moving the neuron from the down state to the up state, while the stimulation of AMPA receptors allows the neuron to reach and surpass the threshold potential. Neurons that have this bistable ability have the potential to be gated because outside gatekeeper neurons can modulate the membrane potential of the gated neuron by selectively shifting them from the up state to the down state. Such mechanisms have been observed in the nucleus accumbens, with gatekeepers originating in the cortex, thalamus and basal ganglia.
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