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Name: Date: Period: _____ Unit 1 Notes, Part 3 – The Importance of
Name: Date: Period: _____ Unit 1 Notes, Part 3 – The Importance of

... must create cells with half the chromosomes of a normal body cell. This way, an egg with 23 chromosomes can meet up with a sperm with 23 chromosomes in a process called fertilization to form a fertilized egg (zygote) with 46 chromosomes. That zygote will then go through normal cell division (mitosis ...
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Chapter Objectives: Chapters 18~19: Genetics of
Chapter Objectives: Chapters 18~19: Genetics of

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3` Untranslated Regions
3` Untranslated Regions

... were published for obtaining coding sequences out of the morass of noncoding DNA. More recently neural networks have been used to locate protein coding regions (Uberbacher and Mural, 1991). Searls (1992, 1997) suggested that DNA exhibits all the characteristics of a language, including a grammar. Ma ...
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Allele: An allele is one of two or more forms of the DNA sequence of

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Leukaemia Section t(11;20)(q23;q11) Atlas of Genetics and Cytogenetics in Oncology and Haematology

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antibiotics may enter the environment having been excreted in the

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The DNA Connection

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Satiable Curiosity - Journal of Genetic Genealogy

... Tandem Repeats or STRs) contained within these segments tend to be more variable, due to their relatively high mutation rate. Genetic genealogists take advantage of this variability when testing the multi-copy markers DYS385a/b, DYS459a/b, DYS464a/b/c/d, YCAIIa/b, and CDYa/b. Although these duplicat ...
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Who Wants to Be a Millionaire?

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Biological Basis for Gene Hunting

... human genome, but they were not easy to detect. Lab techniques such as flourescent in-situ hybridization or FISH (see Section X.X) had been used for some time to detect very specific chromosomal microdeletions. (A microdeletion is a deletion of a large section of DNA, but one too small to see throug ...
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BNFO601 Introduction to Bioinformatics Flow of Information

... tryptophan, methionine, and histidine. Draw a conclusion about how degeneracy relates to the natural frequencies of amino acids. 2. Not all amino acid changes are possible from a single basepair mutation: Virtually all mutations found in nature are single events: single basepair changes or single in ...
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Cre-Lox recombination



In the field of genetics, Cre-Lox recombination is known as a site-specific recombinase technology, and is widely used to carry out deletions, insertions, translocations and inversions at specific sites in the DNA of cells. It allows the DNA modification to be targeted to a specific cell type or be triggered by a specific external stimulus. It is implemented both in eukaryotic and prokaryotic systems.The system consists of a single enzyme, Cre recombinase, that recombines a pair of short target sequences called the Lox sequences. This system can be implemented without inserting any extra supporting proteins or sequences. The Cre enzyme and the original Lox site called the LoxP sequence are derived from bacteriophage P1.Placing Lox sequences appropriately allows genes to be activated, repressed, or exchanged for other genes. At a DNA level many types of manipulations can be carried out. The activity of the Cre enzyme can be controlled so that it is expressed in a particular cell type or triggered by an external stimulus like a chemical signal or a heat shock. These targeted DNA changes are useful in cell lineage tracing and when mutants are lethal if expressed globally.The Cre-Lox system is very similar in action and in usage to the FLP-FRT recombination system.
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