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Taq DNA Polymerase
Taq DNA Polymerase

... Note: For convenience, to simply save the time of whole procedure, please use a High-Stability PCR Kit (Cat. No. L00342) containing Taq DNA polymerase, 10X buffer, and stabilized 10 mM dNTP (Cat. No. C01689), or a single Taq PCR Master Mix (Cat. No.E00019) which includes a premixed solution containi ...
Solutions to Molecular Biology Unit Exam
Solutions to Molecular Biology Unit Exam

... then the protein will certainly be different. Because the location of the stop codon is also altered in this alternative reading frame, the resulting protein might be longer or shorter or even the same. ...
Latent Periodicity of Many Genes
Latent Periodicity of Many Genes

... sequences and to find the biological meaning of the revealed structural features of the sequences. One of such structural features is a periodicity of symbolic sequences. Earlier comprehensive mathematical methods were developed for study of periodicity of continuous and discrete numerical sequences, ...
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... polycloning site. • Recombinogenic engineering can be used to move genes from one vector to another ...
Transposons ※ Transposons are DNA elements that can hop, or
Transposons ※ Transposons are DNA elements that can hop, or

... place in DNA to another. They are also called “jumping genes”. They carry the enzyme, transposase responsible for transposition, the movement by a transposon. ※ They are discovered by Barbara McClintock in the early 1950s. ※ The transposons now exist in all organisms on the earth, including human. ※ ...
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Force vs. Velocity Profiles for Single Molecules of RNAP

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How to accelerate protein search on DNA: Location and dissociation

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2013 Training Handout

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Rhythmic Parsing of Sonified DNA and RNA Sequences

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Mutation, Transposition, and Recombination

... result in syntactically correct phenotypes and much editing is necessary to remove invalid phenotypes. Consequently, mutation does not significantly outperform crossover. On the other hand, GEP is a totally unconstrained genotype/phenotype system as all modifications made in the genotype always resu ...
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... • A set of clones used by geneticists in physically mapping or sequencing a given region is called a contig – Contains contiguous (or overlapping) DNAs spanning long distances – Used like putting together a jigsaw puzzle – Easier to complete with bigger pieces – Helpful to assemble in overlapping fa ...
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CHAPTER 16 THE MOLECULE BASIS OF INHERITANCE
CHAPTER 16 THE MOLECULE BASIS OF INHERITANCE

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Contents Introduction Storage and Stability - Omega Bio-tek

... specially formulated buffer. The protein is precipitated by adding SQ2. After removal of the protein, the supernatant is mixed with 1 volume of isopropanol to precipitate the DNA. The DNA pellet is washed with 70% ethanol and dissolved with water or low ionic strength buffer. Purified DNA can be dir ...
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Cre-Lox recombination



In the field of genetics, Cre-Lox recombination is known as a site-specific recombinase technology, and is widely used to carry out deletions, insertions, translocations and inversions at specific sites in the DNA of cells. It allows the DNA modification to be targeted to a specific cell type or be triggered by a specific external stimulus. It is implemented both in eukaryotic and prokaryotic systems.The system consists of a single enzyme, Cre recombinase, that recombines a pair of short target sequences called the Lox sequences. This system can be implemented without inserting any extra supporting proteins or sequences. The Cre enzyme and the original Lox site called the LoxP sequence are derived from bacteriophage P1.Placing Lox sequences appropriately allows genes to be activated, repressed, or exchanged for other genes. At a DNA level many types of manipulations can be carried out. The activity of the Cre enzyme can be controlled so that it is expressed in a particular cell type or triggered by an external stimulus like a chemical signal or a heat shock. These targeted DNA changes are useful in cell lineage tracing and when mutants are lethal if expressed globally.The Cre-Lox system is very similar in action and in usage to the FLP-FRT recombination system.
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