New Psychoactive Substances NPS
... to be evaluated on a case-by-case basis Treatment of synthetic cathinone intoxication requires more "basic science" research At this time, treatment is mostly palliative ...
... to be evaluated on a case-by-case basis Treatment of synthetic cathinone intoxication requires more "basic science" research At this time, treatment is mostly palliative ...
Assist professor Hayder M. Alkuraishy PROKINETIC and
... therapy. Headache is a common side effect. Electrocardiographic changes, such as a prolonged QT interval, can occur with dolasetron. Patients who may be at risk should take this medication with caution. ...
... therapy. Headache is a common side effect. Electrocardiographic changes, such as a prolonged QT interval, can occur with dolasetron. Patients who may be at risk should take this medication with caution. ...
Antipsychotics
... • The mechanism is not entirely clear, but there is evidence for both increased appetite and altered metabolic control with these drugs • Patient- related factors include pre- existing metabolic issues, and those who are obese, diabetic or pre diabetic, or have high risk lipid profile are more likel ...
... • The mechanism is not entirely clear, but there is evidence for both increased appetite and altered metabolic control with these drugs • Patient- related factors include pre- existing metabolic issues, and those who are obese, diabetic or pre diabetic, or have high risk lipid profile are more likel ...
What do you know about ECSTASY?
... • Muscle tension and aches • jaw clenching • sweating • fatigue • difficulty concentrating & retaining newly learned material • Confusion or delirium even weeks after drug use Occasional Symptoms: • Intense dysphoria (depression, anxiety) ...
... • Muscle tension and aches • jaw clenching • sweating • fatigue • difficulty concentrating & retaining newly learned material • Confusion or delirium even weeks after drug use Occasional Symptoms: • Intense dysphoria (depression, anxiety) ...
Autonomic Nervous System
... “Amine hypothesis of depression”: States that a functional decrease in brain norepinephrine and/or serotonin is responsible for the disorder (maybe over-simplified, BUT => Most anti-depressive drugs facilitate the activity of these brain amines ...
... “Amine hypothesis of depression”: States that a functional decrease in brain norepinephrine and/or serotonin is responsible for the disorder (maybe over-simplified, BUT => Most anti-depressive drugs facilitate the activity of these brain amines ...
SSRIs
... - Used in Schizophrenia – no help with psychosis but less depressed Side effects: (safer than MAOI) - block histamine receptors: produces drowsiness - block acetylcholine receptors: dry mouth, difficulty urinating - Na+ Channels: heart irregularities ...
... - Used in Schizophrenia – no help with psychosis but less depressed Side effects: (safer than MAOI) - block histamine receptors: produces drowsiness - block acetylcholine receptors: dry mouth, difficulty urinating - Na+ Channels: heart irregularities ...
NOOTROPIC DRUGS
... • Endogen depression – the deeper it is, the larger doses, rate of their increasing and duration of treatment should be administered • Step-by-step dose increasing till obtaining of effect, administration of effective dose during 4-6 weeks – 3-6 months, gradual decreasing of dose (during 5-6 weeks) ...
... • Endogen depression – the deeper it is, the larger doses, rate of their increasing and duration of treatment should be administered • Step-by-step dose increasing till obtaining of effect, administration of effective dose during 4-6 weeks – 3-6 months, gradual decreasing of dose (during 5-6 weeks) ...
Prodrugs and active metabolites among antidepressive
... clinically important. Only those ones can be considered clinically important that are produced in significant amount or are at least as active as the parent drug, or are produced in specific tissues, like the brain. Pharmacokinetic properties and clinically important metabolites of antidepressants a ...
... clinically important. Only those ones can be considered clinically important that are produced in significant amount or are at least as active as the parent drug, or are produced in specific tissues, like the brain. Pharmacokinetic properties and clinically important metabolites of antidepressants a ...
New Drugbox Medication
... It works by blocking Serotonin, one of the body’s natural substances that cause vomiting. ...
... It works by blocking Serotonin, one of the body’s natural substances that cause vomiting. ...
Book Reviews
... outstanding and skilled teacher who has his own way of teaching, but it is also true that all excellent teachers are not always high-quality writers. In India, most of the gross anatomists write a textbook at the end of their teaching career. This textbook is not different from the other textbooks a ...
... outstanding and skilled teacher who has his own way of teaching, but it is also true that all excellent teachers are not always high-quality writers. In India, most of the gross anatomists write a textbook at the end of their teaching career. This textbook is not different from the other textbooks a ...
Restless legs syndrome
... Consider only if non-drug treatment and iron supplements do not improve symptoms. The licenced agents are all non-ergot derived dopamine agonists: ropinirole, pramipexole and rotigotine. There is insufficient evidence to recommend one over another. A Cochrane review showed that dopamine agonists imp ...
... Consider only if non-drug treatment and iron supplements do not improve symptoms. The licenced agents are all non-ergot derived dopamine agonists: ropinirole, pramipexole and rotigotine. There is insufficient evidence to recommend one over another. A Cochrane review showed that dopamine agonists imp ...
relationship between food, serotonin and affective
... found in the brain. Therefore, variations in brain TRP levels can change the substrate saturation of tryptophan hydroxylase, and as a consequence, rapidly alter the production rate of 5-HT (5). The ingestion of TRP leads to rapid elevation in brain TRP and 5-HT levels. However, TRP and other large n ...
... found in the brain. Therefore, variations in brain TRP levels can change the substrate saturation of tryptophan hydroxylase, and as a consequence, rapidly alter the production rate of 5-HT (5). The ingestion of TRP leads to rapid elevation in brain TRP and 5-HT levels. However, TRP and other large n ...
Antipsychotic drugs
... Parkinsonian-like syndrome is characterized by tremors, bradykinesia, rigidity, and other signs of parkinsonism. ...
... Parkinsonian-like syndrome is characterized by tremors, bradykinesia, rigidity, and other signs of parkinsonism. ...
Depressants
... synthetic drugs known as benzodiazepines. Both have a common structure consisting of a phenyl (C6H5) group, a fused benzene ring with a seven membered heterocyclic ring consisting of two nitrogen atoms, one of which is a secondary amine. ...
... synthetic drugs known as benzodiazepines. Both have a common structure consisting of a phenyl (C6H5) group, a fused benzene ring with a seven membered heterocyclic ring consisting of two nitrogen atoms, one of which is a secondary amine. ...
Nick Potts Presenttion
... Theory is R-citalopram may interfere with binding of Scitalopram at the serotonin transporter, thus ? Twice as potent and ? quicker onset Data suggesting that escitalopram is better anxiolytic that citalopram ...
... Theory is R-citalopram may interfere with binding of Scitalopram at the serotonin transporter, thus ? Twice as potent and ? quicker onset Data suggesting that escitalopram is better anxiolytic that citalopram ...
cnspharmacology
... in the optimal coordination and performance of movements. It also plays a role in learning and memory. Lesions to the cerebellum result in ataxia, reduced muscle tone, delayed initiation of movements, nystagmus, dysarthria, and oscillation at end movements. E. BASAL GANGLIA-Are deep nuclei of the c ...
... in the optimal coordination and performance of movements. It also plays a role in learning and memory. Lesions to the cerebellum result in ataxia, reduced muscle tone, delayed initiation of movements, nystagmus, dysarthria, and oscillation at end movements. E. BASAL GANGLIA-Are deep nuclei of the c ...
Can`t I Just Take a Pill For It?
... apnea, Sigrid C. Veasey et al.7 postulated that it could be useful for obstructive sleep apnea. In 2001, they compared the effects of two doses (20 mg and 40 mg) of ondansetron on English bulldogs. The 40 mg dose reduced the respiratory disturbance index (RBI) by 50 percent during REM sleep. Despite ...
... apnea, Sigrid C. Veasey et al.7 postulated that it could be useful for obstructive sleep apnea. In 2001, they compared the effects of two doses (20 mg and 40 mg) of ondansetron on English bulldogs. The 40 mg dose reduced the respiratory disturbance index (RBI) by 50 percent during REM sleep. Despite ...
Drugs Used to Treat Autism and their Effectiveness
... Treating Anxiety and Depression • Selective serotonin reuptake inhibitors (SSRIs) are prescribed for anxiety, depression, and/or obsessivecompulsive disorder. Of these only fluoxetine (Prozac) has been approved by the FDA for both OCD and depression in children age 7 and older. • Sertraline (Zoloft ...
... Treating Anxiety and Depression • Selective serotonin reuptake inhibitors (SSRIs) are prescribed for anxiety, depression, and/or obsessivecompulsive disorder. Of these only fluoxetine (Prozac) has been approved by the FDA for both OCD and depression in children age 7 and older. • Sertraline (Zoloft ...
Anti-psychotic Meds (CC)
... constipation, urinary retention, bowel obstruction, dilated pupils, blurred vision, increased heart rate, and decreased sweating. Other symptoms that affect the CNS are: impaired concentration, confusion, attention deficit, and memory impairment. ...
... constipation, urinary retention, bowel obstruction, dilated pupils, blurred vision, increased heart rate, and decreased sweating. Other symptoms that affect the CNS are: impaired concentration, confusion, attention deficit, and memory impairment. ...
Problems with synapses File
... NOT stimulate the post-synaptic receptors. Dopamine agonists also have a similar shape/structure to dopamine but they DO stimulate the post-synaptic receptors ...
... NOT stimulate the post-synaptic receptors. Dopamine agonists also have a similar shape/structure to dopamine but they DO stimulate the post-synaptic receptors ...
Definitions
... (VTA) (tegmentum, Latin for covering) is part of the midbrain, lying close to the substantia nigra. • The ventral tegmentum is considered to be part of the pleasure system, or reward circuit, one of the major sources of incentive and behavioral motivation. Activities that produce pleasure tend to ac ...
... (VTA) (tegmentum, Latin for covering) is part of the midbrain, lying close to the substantia nigra. • The ventral tegmentum is considered to be part of the pleasure system, or reward circuit, one of the major sources of incentive and behavioral motivation. Activities that produce pleasure tend to ac ...
Gero-Rehab Course
... fatigue, fever, headache, hyperkinesia, insomnia, nervousness, neuroleptic malignant syndrome– like reaction, paresthesia, serotonin syndrome, suicidal ideation, tremor, weakness, yawning CV: Palpitations EENT: Dry mouth, epistaxis, sinusitis, vision changes ENDO: Syndrome of inappropriate ADH secre ...
... fatigue, fever, headache, hyperkinesia, insomnia, nervousness, neuroleptic malignant syndrome– like reaction, paresthesia, serotonin syndrome, suicidal ideation, tremor, weakness, yawning CV: Palpitations EENT: Dry mouth, epistaxis, sinusitis, vision changes ENDO: Syndrome of inappropriate ADH secre ...
Children and Medications
... inhibitors (SSRIs) • differ from each other mainly in adverse effects • helpful in depression, anxiety, obsessive compulsive symptoms • may help self-injurious behaviour in severe learning disability and autism • a few children become silly and socially disinhibited ...
... inhibitors (SSRIs) • differ from each other mainly in adverse effects • helpful in depression, anxiety, obsessive compulsive symptoms • may help self-injurious behaviour in severe learning disability and autism • a few children become silly and socially disinhibited ...
Serotonin syndrome
Serotonin syndrome is a potential symptom of any number of life-threatening drug interactions which may follow therapeutic drug use, combination, overdose of particular drugs, or the recreational use of certain drugs. Serotonin syndrome is not an idiopathic drug reaction; it is a predictable consequence of excess serotonin on the CNS and/or peripheral nervous system. For this reason, some experts strongly prefer the terms serotonin toxicity or serotonin toxidrome which more accurately reflect that it is a form of poisoning. Other names include serotonin sickness, serotonin storm, serotonin poisoning, hyperserotonemia, or serotonergic syndrome.Excessive levels of serotonin produce a spectrum of specific symptoms including cognitive, autonomic, and somatic effects. Symptoms may range from barely perceptible to fatal. Numerous drugs and drug combinations have been reported to produce serotonin syndrome, though the exact mechanism is not well understood in many instances.Diagnosis includes observing symptoms and investigating patient history for causal factors (interacting drugs). The syndrome has a characteristic picture but can be mistaken for other illnesses in some people, particularly those with neuroleptic malignant syndrome. No laboratory tests can currently confirm the diagnosis. Hence it is diagnosed based on symptoms, disease course (that is, the progression of the disease) and the exclusion of other possible causes of the presenting symptoms.Treatment consists of discontinuing medications which may contribute and in moderate to severe cases administering a serotonin antagonist. An important adjunct treatment includes controlling agitation with benzodiazepine sedation. The high-profile case of Libby Zion, who is generally accepted to have died from serotonin syndrome, resulted in changes to graduate medical education in New York State.