CATECHOLAMINES - Drexel University College of Medicine
... • The majority of patients in each group discontinued their assigned treatment owing to inefficacy or intolerable side effects or for other reasons. • Olanzapine was the most effective in terms of the rates of discontinuation, however it was associated with greater weight gain and increases in measu ...
... • The majority of patients in each group discontinued their assigned treatment owing to inefficacy or intolerable side effects or for other reasons. • Olanzapine was the most effective in terms of the rates of discontinuation, however it was associated with greater weight gain and increases in measu ...
Side effects
... - Used in Schizophrenia – no help with psychosis but less depressed Side effects: (safer than MAOI) - block histamine receptors: produces drowsiness - block acetylcholine receptors: dry mouth, difficulty urinating - Na+ Channels: heart irregularities ...
... - Used in Schizophrenia – no help with psychosis but less depressed Side effects: (safer than MAOI) - block histamine receptors: produces drowsiness - block acetylcholine receptors: dry mouth, difficulty urinating - Na+ Channels: heart irregularities ...
Amy Hyatt - InvisionFree
... headache, dizziness, tremor, agitation, sweating, and insomnia, weight loss. 6. State the advantages and disadvantages of SSRI’s over the TCA’s. Advantages: Unlike many of the TCA’s, the SSRI’s tend to produce CNS stimulation (activation) rather than CNS depression. There is an increase in the dur ...
... headache, dizziness, tremor, agitation, sweating, and insomnia, weight loss. 6. State the advantages and disadvantages of SSRI’s over the TCA’s. Advantages: Unlike many of the TCA’s, the SSRI’s tend to produce CNS stimulation (activation) rather than CNS depression. There is an increase in the dur ...
2- H1 and H2 Receptors
... 1-Physiologic antagonists, especially epinephrine, have smooth muscle actions opposite to those of histamine, but they act at different receptors. This is important clinically because injection of epinephrine can be lifesaving in systemic anaphylaxis 2-Release inhibitors reduce the degranulation of ...
... 1-Physiologic antagonists, especially epinephrine, have smooth muscle actions opposite to those of histamine, but they act at different receptors. This is important clinically because injection of epinephrine can be lifesaving in systemic anaphylaxis 2-Release inhibitors reduce the degranulation of ...
Combining antidepressants
... strategies is to broaden the effect on the CNS by combining agents that act on different neurotransmitter systems. There are three main ways to increase neurotransmission: ...
... strategies is to broaden the effect on the CNS by combining agents that act on different neurotransmitter systems. There are three main ways to increase neurotransmission: ...
drugs of abuse
... • It come as an off- white powder or ‘rock’ • It modifies the action of dopamine in the brain by inhibiting its re-uptake from the synaptic cleft and thus causing prolonged postsynaptic stimulation. • Mostly act on the ‘reward pathway 'which consists of ventral segmental area, nucleus accumbens and ...
... • It come as an off- white powder or ‘rock’ • It modifies the action of dopamine in the brain by inhibiting its re-uptake from the synaptic cleft and thus causing prolonged postsynaptic stimulation. • Mostly act on the ‘reward pathway 'which consists of ventral segmental area, nucleus accumbens and ...
Product Features KEY BENEFITS Avisae OptimALL Nutrition™ bliss
... delivers its benefits via a simple, flavorless oral spray which can be used at any time of day. ...
... delivers its benefits via a simple, flavorless oral spray which can be used at any time of day. ...
Ecstasy and Consciousness
... Combination of stimulant effects, mild hallucinogen-like effects, plus more unique emotional effects ...
... Combination of stimulant effects, mild hallucinogen-like effects, plus more unique emotional effects ...
benzodiazepines - Website of Neelay Gandhi
... Psychochemical straightjacket Most adverse effects occur early, antipsychotic effects take weeks severe impairment of quality of life 1. Extrapyramidal motor effects: -acute dystonias (mouth, face, eye) which the patient is fully aware of and has not control over it at all; very embarrassing to pa ...
... Psychochemical straightjacket Most adverse effects occur early, antipsychotic effects take weeks severe impairment of quality of life 1. Extrapyramidal motor effects: -acute dystonias (mouth, face, eye) which the patient is fully aware of and has not control over it at all; very embarrassing to pa ...
Lecture 14
... “Amine hypothesis of depression”: States that a functional decrease in brain norepinephrine and/or serotonin is responsible for the disorder (maybe over-simplified, BUT => Most anti-depressive drugs facilitate the activity of these brain amines ...
... “Amine hypothesis of depression”: States that a functional decrease in brain norepinephrine and/or serotonin is responsible for the disorder (maybe over-simplified, BUT => Most anti-depressive drugs facilitate the activity of these brain amines ...
Product Monograph - Paladin Labs Inc.
... antihistaminic substances. Concomitant use with MAOIs should therefore be avoided (see CONTRAINDICATIONS). ...
... antihistaminic substances. Concomitant use with MAOIs should therefore be avoided (see CONTRAINDICATIONS). ...
Outline and evaluate biological explanations for depression. 8 + 16
... However, while the drugs raise levels of the noradrenaline immediately the symptoms of low mood take a couple of weeks at least to be relieved. This suggests that there must be other factors involved. As Tricyclics work on serotonin as well as noradrenaline, it was considered that serotonin may have ...
... However, while the drugs raise levels of the noradrenaline immediately the symptoms of low mood take a couple of weeks at least to be relieved. This suggests that there must be other factors involved. As Tricyclics work on serotonin as well as noradrenaline, it was considered that serotonin may have ...
moravek-arma1
... - Parallel abuse of opiates and cocaine could potentiate mood disorders - Higher risk of overdose - Higher suicidal risk - Terepautic plan is more complex to define ...
... - Parallel abuse of opiates and cocaine could potentiate mood disorders - Higher risk of overdose - Higher suicidal risk - Terepautic plan is more complex to define ...
Neurotransmitter Notes
... have a profound influence on overall health and well-being. When our concentration and focus is good, we feel more directed, motivated, and vibrant. Unfortunately, if neurotransmitter levels are inadequate these energizing and motivating signals are absent and we feel more stressed, sluggish, and ou ...
... have a profound influence on overall health and well-being. When our concentration and focus is good, we feel more directed, motivated, and vibrant. Unfortunately, if neurotransmitter levels are inadequate these energizing and motivating signals are absent and we feel more stressed, sluggish, and ou ...
complementary and alternative therapies
... 3. Dosage—300mg TID of the standardized extract of 3% hypericum b. 5-adenosyl-methionine or SAM-e (pronounced Sammy)—“the -breakthrough supplement that works as well as prescription drugs, in half the time with no side effects.” (Brown, R, Bottiglieri T. Stop Depression Now. Putnam, 1999)—hmmmm—too ...
... 3. Dosage—300mg TID of the standardized extract of 3% hypericum b. 5-adenosyl-methionine or SAM-e (pronounced Sammy)—“the -breakthrough supplement that works as well as prescription drugs, in half the time with no side effects.” (Brown, R, Bottiglieri T. Stop Depression Now. Putnam, 1999)—hmmmm—too ...
Overdose in the Emergency Department
... Activated charcoal: 1 g/kg Clinical Toxicology position paper 2005: “activated charcoal should not be used routinely” AC can be considered if Ingestion of potentially toxic amount of poison that will be absorbed by charcoal within one hour of ...
... Activated charcoal: 1 g/kg Clinical Toxicology position paper 2005: “activated charcoal should not be used routinely” AC can be considered if Ingestion of potentially toxic amount of poison that will be absorbed by charcoal within one hour of ...
Pharmacology Tutoring for Sedative Hypnotics and Antiemetics
... The dose of zaleplon should be half of what it is in men b. Risk of next day driving is a concern when taking eszopiclone c. All benzodiazepine agonists should only be taken for 7-10 days d. Zolpidem is the most likely of these drugs to produce hangover at therapeutic doses a. ...
... The dose of zaleplon should be half of what it is in men b. Risk of next day driving is a concern when taking eszopiclone c. All benzodiazepine agonists should only be taken for 7-10 days d. Zolpidem is the most likely of these drugs to produce hangover at therapeutic doses a. ...
Cannabinoids
... these receptors to inhibit adenylate cyclase activity What is the endogenous ligand? Are these receptors responsible for the CNS effects of D9THC? ...
... these receptors to inhibit adenylate cyclase activity What is the endogenous ligand? Are these receptors responsible for the CNS effects of D9THC? ...
What do you know about ECSTASY?
... “stacking” -– taking 3 or more tablets at once and/or – mixing MDMA with herbal ecstasy, LSD, alcohol, marijuana, and other drugs of abuse ...
... “stacking” -– taking 3 or more tablets at once and/or – mixing MDMA with herbal ecstasy, LSD, alcohol, marijuana, and other drugs of abuse ...
Biotech Daily Neuren: ‘NNZ-2566 Phase II Safety, Efficacy For Rett Syndrome’
... 70mg/kg twice daily were safe and well-tolerated, with no drug related serious adverse events and that the higher dose met several of the efficacy secondary endpoints. The company said the next step would be to submit applications to the US Food and Drug Administration for both orphan drug and break ...
... 70mg/kg twice daily were safe and well-tolerated, with no drug related serious adverse events and that the higher dose met several of the efficacy secondary endpoints. The company said the next step would be to submit applications to the US Food and Drug Administration for both orphan drug and break ...
PR OZA C - Family Guardian
... accused or convicted of rape, assault and arson. Dutch scientists reported a finding in 1993 that helped explain their behavior: The men were missing an enzyme called monoamine oxidase A, or MAO-A, which breaks down serotonin leading to high levels of serotonin just as the mutant mice have. [Keep in ...
... accused or convicted of rape, assault and arson. Dutch scientists reported a finding in 1993 that helped explain their behavior: The men were missing an enzyme called monoamine oxidase A, or MAO-A, which breaks down serotonin leading to high levels of serotonin just as the mutant mice have. [Keep in ...
PSYC 342: Psychopharmacology
... • A syndrome present in many illnesses – remove known cause or treat underlying illness – treat symptomatically with antipsychotic medications ...
... • A syndrome present in many illnesses – remove known cause or treat underlying illness – treat symptomatically with antipsychotic medications ...
Appendix 9: Drugs used in ASD
... 0.2 to 0.5 mg/kg/day in 2 divided As for fluoxetine. doses Possible increase in suicidal Retail pharmacy ideation in adolescents. Loxamine brand fully subsidised Tablet: 20mg ...
... 0.2 to 0.5 mg/kg/day in 2 divided As for fluoxetine. doses Possible increase in suicidal Retail pharmacy ideation in adolescents. Loxamine brand fully subsidised Tablet: 20mg ...
Club Drugs Quiz
... MDMA TOXICITY • SIMILAR TO HEAT STROKE • URINARY pH LESS THAN 5.6 IN METABOLIC ACIDOSIS • CAUSES MYOGLUBIN CASTS • HYPERKALEMIA RELATED TO CARDIAC ARRYTHMIA • WATER INTOXICATION ...
... MDMA TOXICITY • SIMILAR TO HEAT STROKE • URINARY pH LESS THAN 5.6 IN METABOLIC ACIDOSIS • CAUSES MYOGLUBIN CASTS • HYPERKALEMIA RELATED TO CARDIAC ARRYTHMIA • WATER INTOXICATION ...
possible implications for pharmacotherapy of Alzheimer`s
... absence, respectively, of delusions or halluciDevelopment of pharmacotherapy for Alzhei- nations, or both.9 The unipolar psychotic mer's disease with agents that would aim to group had three men and five women with a improve, if not restore, neurotransmission has mean age of 60 (46-74) years. The un ...
... absence, respectively, of delusions or halluciDevelopment of pharmacotherapy for Alzhei- nations, or both.9 The unipolar psychotic mer's disease with agents that would aim to group had three men and five women with a improve, if not restore, neurotransmission has mean age of 60 (46-74) years. The un ...
Serotonin syndrome
Serotonin syndrome is a potential symptom of any number of life-threatening drug interactions which may follow therapeutic drug use, combination, overdose of particular drugs, or the recreational use of certain drugs. Serotonin syndrome is not an idiopathic drug reaction; it is a predictable consequence of excess serotonin on the CNS and/or peripheral nervous system. For this reason, some experts strongly prefer the terms serotonin toxicity or serotonin toxidrome which more accurately reflect that it is a form of poisoning. Other names include serotonin sickness, serotonin storm, serotonin poisoning, hyperserotonemia, or serotonergic syndrome.Excessive levels of serotonin produce a spectrum of specific symptoms including cognitive, autonomic, and somatic effects. Symptoms may range from barely perceptible to fatal. Numerous drugs and drug combinations have been reported to produce serotonin syndrome, though the exact mechanism is not well understood in many instances.Diagnosis includes observing symptoms and investigating patient history for causal factors (interacting drugs). The syndrome has a characteristic picture but can be mistaken for other illnesses in some people, particularly those with neuroleptic malignant syndrome. No laboratory tests can currently confirm the diagnosis. Hence it is diagnosed based on symptoms, disease course (that is, the progression of the disease) and the exclusion of other possible causes of the presenting symptoms.Treatment consists of discontinuing medications which may contribute and in moderate to severe cases administering a serotonin antagonist. An important adjunct treatment includes controlling agitation with benzodiazepine sedation. The high-profile case of Libby Zion, who is generally accepted to have died from serotonin syndrome, resulted in changes to graduate medical education in New York State.