Exercise and Post Polio Syndrome
... Decades after contracting the polio virus, individuals may begin to experi- ence new weakness, pain and fatigue. Managing these new symptoms dif- fers for each person. It is recommended that polio survivors seek treatment from specialists familiar with Post Po ...
... Decades after contracting the polio virus, individuals may begin to experi- ence new weakness, pain and fatigue. Managing these new symptoms dif- fers for each person. It is recommended that polio survivors seek treatment from specialists familiar with Post Po ...
Biopsychosocial Model For Psychosis
... • Typical antipsychotics (oral or depot) – none of proven greater efficacy – 300 - 500 chlorpromazine equivalents required – 80 % respond but • commonly left with residuum • significant side effects – movement disorder EPSE, akathisia, tardive dyskinesia – sedation – anticholinergic ...
... • Typical antipsychotics (oral or depot) – none of proven greater efficacy – 300 - 500 chlorpromazine equivalents required – 80 % respond but • commonly left with residuum • significant side effects – movement disorder EPSE, akathisia, tardive dyskinesia – sedation – anticholinergic ...
The Relationship between Psychoactive Drugs, the Brain and
... Albert Hofmann. Contrary to most other drugs, there have been extensive laboratory studies on animals concerning the effects of LSD. LSD is normally orally ingested by licking small squares of blotter paper that have been soaked in the drug as well as in the form of tablets called ‘microdots’. LSD p ...
... Albert Hofmann. Contrary to most other drugs, there have been extensive laboratory studies on animals concerning the effects of LSD. LSD is normally orally ingested by licking small squares of blotter paper that have been soaked in the drug as well as in the form of tablets called ‘microdots’. LSD p ...
Prescribing Information
... suicidality in certain patients during the early phases of treatment. Pooled analyses of shortterm placebo-controlled studies of antidepressant drugs (selective serotonin reuptake inhibitors [SSRIs] and others) showed that these drugs increase the risk of suicidal thinking and behavior (suicidality) ...
... suicidality in certain patients during the early phases of treatment. Pooled analyses of shortterm placebo-controlled studies of antidepressant drugs (selective serotonin reuptake inhibitors [SSRIs] and others) showed that these drugs increase the risk of suicidal thinking and behavior (suicidality) ...
CYAMEMAZINE
... CNS depressants • Anticholinergic effects may occur if used with atropine or related compounds • Some patients taking a neuroleptic and lithium have developed an encephalopathic syndrome similar to neuroleptic malignant syndrome • Epinephrine may lower blood pressure; diuretics and alcohol may incre ...
... CNS depressants • Anticholinergic effects may occur if used with atropine or related compounds • Some patients taking a neuroleptic and lithium have developed an encephalopathic syndrome similar to neuroleptic malignant syndrome • Epinephrine may lower blood pressure; diuretics and alcohol may incre ...
CNS pharmacology
... - decreased post-synaptic sensitivity NB serotonin, nor-adrenaline and dopamine - all effected by anti-depressants Anti-depressants therapeutic effect: increasing NT levels or decreasing re-uptake ...
... - decreased post-synaptic sensitivity NB serotonin, nor-adrenaline and dopamine - all effected by anti-depressants Anti-depressants therapeutic effect: increasing NT levels or decreasing re-uptake ...
Antidepressant Presentation
... Tianeptine, a 5-HT reuptake enhancer that works opposite to SSRIs, is a marketed antidepressant A selective TH inhibitor shows activity in an animal model of ...
... Tianeptine, a 5-HT reuptake enhancer that works opposite to SSRIs, is a marketed antidepressant A selective TH inhibitor shows activity in an animal model of ...
Hallucinogens
... - A short-acting hallucinogen - Found in seeds of certain leguminous trees and prepared synthetically. - It is inhaled and similar action as psilocybin. - High doses can be quite intoxicating. - Can also cause unpleasant reactions/\. ...
... - A short-acting hallucinogen - Found in seeds of certain leguminous trees and prepared synthetically. - It is inhaled and similar action as psilocybin. - High doses can be quite intoxicating. - Can also cause unpleasant reactions/\. ...
GENERIC NAME: sertraline
... Symptoms may include sweating, trembling, a sensation of choking, lightheadedness, fear of losing control, fear of dying, or chills. Sertraline also is used to treat post-traumatic stress disorder (PTSD). PTSD is a combination of symptoms that leads to distressing changes in personality and behavior ...
... Symptoms may include sweating, trembling, a sensation of choking, lightheadedness, fear of losing control, fear of dying, or chills. Sertraline also is used to treat post-traumatic stress disorder (PTSD). PTSD is a combination of symptoms that leads to distressing changes in personality and behavior ...
Clinical Refresher on Depression and Anxiety
... episode will go on to have a manic episode in the future. Consider: psychotherapy, social work, occupational therapy, counselling, social and specific support groups. ...
... episode will go on to have a manic episode in the future. Consider: psychotherapy, social work, occupational therapy, counselling, social and specific support groups. ...
Lower Serotonin Transporter Binding Potential in the Human Brain
... characteristics are summarized in Table 1. Inclusion criteria for subjects with major depressive disorder were 1) age 18–65 years; 2) fulfillment of the DSM-IV criteria for major depressive episode; 3) absence of any psychotropic medication use for at least 2 weeks before the PET scan (6 weeks for f ...
... characteristics are summarized in Table 1. Inclusion criteria for subjects with major depressive disorder were 1) age 18–65 years; 2) fulfillment of the DSM-IV criteria for major depressive episode; 3) absence of any psychotropic medication use for at least 2 weeks before the PET scan (6 weeks for f ...
Amphetamines Megan Trimble 3/28/06
... Defining the term: The more of this drug you consume, the higher you want get and the harder it is to do so. The user takes increasing amounts without sleeping which can result in being beyond high, for days at a time ...
... Defining the term: The more of this drug you consume, the higher you want get and the harder it is to do so. The user takes increasing amounts without sleeping which can result in being beyond high, for days at a time ...
CLINTON E. CANAL, PH.D. CURRICULUM VITAE
... This project is to advance novel phenylaminotetralin (PAT) analogs as functionally-selective serotonin 5-HT2 receptor-based drug development candidates to treat amphetamine and methamphetamine abuse. Role: Co-I Total Costs: $1,802,016 Pending R21 DA040907 Canal/Murnane ...
... This project is to advance novel phenylaminotetralin (PAT) analogs as functionally-selective serotonin 5-HT2 receptor-based drug development candidates to treat amphetamine and methamphetamine abuse. Role: Co-I Total Costs: $1,802,016 Pending R21 DA040907 Canal/Murnane ...
Novel psychoactive substances of interest for psychiatry
... Typically, synthetic cathinones are snorted or ingested orally or injected. For mephedrone, the half-life is as short as one hour, hence the re-dosing risk (60). Each synthetic cathinone has variable effects and potency levels on serotonin, dopamine and noradrenaline pathways, but all typically poss ...
... Typically, synthetic cathinones are snorted or ingested orally or injected. For mephedrone, the half-life is as short as one hour, hence the re-dosing risk (60). Each synthetic cathinone has variable effects and potency levels on serotonin, dopamine and noradrenaline pathways, but all typically poss ...
Neuraxial Opioid-Induced Pruritus: A Review
... administration of opioids is a common side effect, to date few studies have elucidated the mechanisms, mediators, neural pathways & pathophysiology of this symptom. A better understanding of the pathophysiology would lead to improved preventative & treatment strategies. ...
... administration of opioids is a common side effect, to date few studies have elucidated the mechanisms, mediators, neural pathways & pathophysiology of this symptom. A better understanding of the pathophysiology would lead to improved preventative & treatment strategies. ...
TOXICOLOGY Case: DRESS Syndrome LETTER 1-800-222-1222
... dizziness, headache, memory impairment, insomnia, and gastrointestinal effects, including nausea, vomiting, diarrhea, and dry mouth2. Rare, serious side effects include arrhythmias, hyper- or hypotension, hemolytic anemia, leukocytosis, methemoglobinemia, and seizures2. One of the more common, but e ...
... dizziness, headache, memory impairment, insomnia, and gastrointestinal effects, including nausea, vomiting, diarrhea, and dry mouth2. Rare, serious side effects include arrhythmias, hyper- or hypotension, hemolytic anemia, leukocytosis, methemoglobinemia, and seizures2. One of the more common, but e ...
chasing_the_dragon_grand_rounds2
... leads to feelings of increased physical and mental powers and euphoria • Can also cause agitation, nausea, bruxism, ataxia, diaphoresis, blurry vision, tachycardia and hypertension • Rarely causes hypertensive emergencies, intracranial hemorrhage, MI, aortic dissection and dysrhythmias ...
... leads to feelings of increased physical and mental powers and euphoria • Can also cause agitation, nausea, bruxism, ataxia, diaphoresis, blurry vision, tachycardia and hypertension • Rarely causes hypertensive emergencies, intracranial hemorrhage, MI, aortic dissection and dysrhythmias ...
Norepinephrine
... Phentermine is used together with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes. Phentermine is used to counteract the effect of morphine in cancer patient ( narcotic effect) . The first sign that appears ...
... Phentermine is used together with diet and exercise to treat obesity (overweight) in people with risk factors such as high blood pressure, high cholesterol, or diabetes. Phentermine is used to counteract the effect of morphine in cancer patient ( narcotic effect) . The first sign that appears ...
Neul – Clinical trials family
... Achieved its primary endpoint - both dose levels of NNZ-2566 were welltolerated after 28 days of treatment and no safety concerns were identified. Higher dose exceeded the pre-specified criteria for improvement in core efficacy measures compared with placebo on group and subject level analysis ...
... Achieved its primary endpoint - both dose levels of NNZ-2566 were welltolerated after 28 days of treatment and no safety concerns were identified. Higher dose exceeded the pre-specified criteria for improvement in core efficacy measures compared with placebo on group and subject level analysis ...
CNS Depressants and Antidepressants
... benzodiazepines in their blood The effect of benzodiazepines on driving performance is variable and not always easy to predict ...
... benzodiazepines in their blood The effect of benzodiazepines on driving performance is variable and not always easy to predict ...
Drugs Affecting the Gastrointestinal System and Nutrition
... Have client take with 8 ounces of water. If powdered form needs to be mixed with 8 ounces of water. Fluid must be taken immediately to avoid swelling of the product in the throat or esophagus or fecal impaction. Best for clients with chronic constipation. ...
... Have client take with 8 ounces of water. If powdered form needs to be mixed with 8 ounces of water. Fluid must be taken immediately to avoid swelling of the product in the throat or esophagus or fecal impaction. Best for clients with chronic constipation. ...
Biological Treatments for depression (PPH) 2011
... Some of the less common but more severe side-effects have been noted to be: loss of appetite, unusual weight loss, unusual or severe mental/mood changes, uncontrolled movements (tremor), decreased interest in sex, and flu-like symptoms. Much more unlikely but potentially very serious side-effects as ...
... Some of the less common but more severe side-effects have been noted to be: loss of appetite, unusual weight loss, unusual or severe mental/mood changes, uncontrolled movements (tremor), decreased interest in sex, and flu-like symptoms. Much more unlikely but potentially very serious side-effects as ...
Anxiety - Psychiatry Training
... Both Types -Effect size (mean symptom change) broadly similar for all agents; main points of differentiation may be in speed of onset; types of side effects; pharmacodynamic interactions (e.g. alcohol); metabolic interactions (some SSRIs) ...
... Both Types -Effect size (mean symptom change) broadly similar for all agents; main points of differentiation may be in speed of onset; types of side effects; pharmacodynamic interactions (e.g. alcohol); metabolic interactions (some SSRIs) ...
Gastro17-GIPharm2
... o Metoclopramide (Reglan) – KNOW THIS ONE!!! o Trimethobenzamide (Tigan) – similar, but less efficacious Important prokinetic effects = increases gastric emptying and motility of GI tract Blocks both D2 and 5-HT3 receptors, 5-HT4 agonist o Serotonin blockade is more important than dopamine block ...
... o Metoclopramide (Reglan) – KNOW THIS ONE!!! o Trimethobenzamide (Tigan) – similar, but less efficacious Important prokinetic effects = increases gastric emptying and motility of GI tract Blocks both D2 and 5-HT3 receptors, 5-HT4 agonist o Serotonin blockade is more important than dopamine block ...
Serotonin syndrome
Serotonin syndrome is a potential symptom of any number of life-threatening drug interactions which may follow therapeutic drug use, combination, overdose of particular drugs, or the recreational use of certain drugs. Serotonin syndrome is not an idiopathic drug reaction; it is a predictable consequence of excess serotonin on the CNS and/or peripheral nervous system. For this reason, some experts strongly prefer the terms serotonin toxicity or serotonin toxidrome which more accurately reflect that it is a form of poisoning. Other names include serotonin sickness, serotonin storm, serotonin poisoning, hyperserotonemia, or serotonergic syndrome.Excessive levels of serotonin produce a spectrum of specific symptoms including cognitive, autonomic, and somatic effects. Symptoms may range from barely perceptible to fatal. Numerous drugs and drug combinations have been reported to produce serotonin syndrome, though the exact mechanism is not well understood in many instances.Diagnosis includes observing symptoms and investigating patient history for causal factors (interacting drugs). The syndrome has a characteristic picture but can be mistaken for other illnesses in some people, particularly those with neuroleptic malignant syndrome. No laboratory tests can currently confirm the diagnosis. Hence it is diagnosed based on symptoms, disease course (that is, the progression of the disease) and the exclusion of other possible causes of the presenting symptoms.Treatment consists of discontinuing medications which may contribute and in moderate to severe cases administering a serotonin antagonist. An important adjunct treatment includes controlling agitation with benzodiazepine sedation. The high-profile case of Libby Zion, who is generally accepted to have died from serotonin syndrome, resulted in changes to graduate medical education in New York State.