Slides PPT - The University of Sydney
... mobilise and shunt energy reserves to where they are most needed ...
... mobilise and shunt energy reserves to where they are most needed ...
Opioids OD fact sheet
... Dextropropoxyphene: significant Na channel blocking effect ( long QRS, HB, arrhythmia), seizures if >1g, may require larger doses of naloxone, can cause death in <1hr Tramadol: µ-receptor and M1 action; inhibits reuptake of 5-HT and NAD, stimulate 5-HT release; toxic dose > 1.5g (>10mg/kg); 70-90% ...
... Dextropropoxyphene: significant Na channel blocking effect ( long QRS, HB, arrhythmia), seizures if >1g, may require larger doses of naloxone, can cause death in <1hr Tramadol: µ-receptor and M1 action; inhibits reuptake of 5-HT and NAD, stimulate 5-HT release; toxic dose > 1.5g (>10mg/kg); 70-90% ...
Luvox (fluvoxamine)
... in excessive levels of the neurotransmitter serotonin when combined with Luvox and produce a toxic syndrome known as serotonin syndrome. The early signs of serotonin syndrome are restlessness, confusion, tremors, flushing, and involuntary muscle jerks. If the medications are not stopped, the individ ...
... in excessive levels of the neurotransmitter serotonin when combined with Luvox and produce a toxic syndrome known as serotonin syndrome. The early signs of serotonin syndrome are restlessness, confusion, tremors, flushing, and involuntary muscle jerks. If the medications are not stopped, the individ ...
EVEKEO® (amphetamine sulfate tablets, USP) DESCRIPTION
... reports at different times and at therapeutic doses in all age groups throughout the course of treatment. Signs and symptoms generally improve after reduction in dose or discontinuation of drug. Careful observation for digital changes is necessary during treatment with ADHD stimulants. Further clini ...
... reports at different times and at therapeutic doses in all age groups throughout the course of treatment. Signs and symptoms generally improve after reduction in dose or discontinuation of drug. Careful observation for digital changes is necessary during treatment with ADHD stimulants. Further clini ...
NURS 1950 Nancy Pares, RN, MSN Metro Community College
... ◦ ETOH, anesthetics, MAO inhibitors, antihistamines, TCA’s, narcotics, barbiturates ◦ Caffeine and smoking interfere with desired effect ...
... ◦ ETOH, anesthetics, MAO inhibitors, antihistamines, TCA’s, narcotics, barbiturates ◦ Caffeine and smoking interfere with desired effect ...
Monoamine Oxidase Inhibitors (MAOIs)
... Most cases of major depression can be treated successfully, usually with medication, psychotherapy, or both. The combination of psychotherapy and antidepressants is very effective in treating moderate to severe depression. The medications improve mood, sleep, energy, and appetite, while therapy stre ...
... Most cases of major depression can be treated successfully, usually with medication, psychotherapy, or both. The combination of psychotherapy and antidepressants is very effective in treating moderate to severe depression. The medications improve mood, sleep, energy, and appetite, while therapy stre ...
IOSR Journal of Pharmacy and Biological Sciences (IOSR-JPBS)
... hospitalized patients. According to a World Health report about 450 million people suffer from a mental or behavioral disorder, yet only a small proportion of them receive even the basic treatment. Depression accounts for about 12% of the global burden of disease which is expected to rise to 15% by ...
... hospitalized patients. According to a World Health report about 450 million people suffer from a mental or behavioral disorder, yet only a small proportion of them receive even the basic treatment. Depression accounts for about 12% of the global burden of disease which is expected to rise to 15% by ...
26_Intracranial Regulation_Dementia-Delirium
... Delirium may or may not have memory loss The individually is often agitated and frightened Disorientation to place, time, even self May have hallucinations and delusions Delirium constitutes a major safety risk for hospitalized patients Depending on the underlying cause, delirium may be li ...
... Delirium may or may not have memory loss The individually is often agitated and frightened Disorientation to place, time, even self May have hallucinations and delusions Delirium constitutes a major safety risk for hospitalized patients Depending on the underlying cause, delirium may be li ...
Safer Prescribing of Antidepressants Guidelines
... dose dependent. For example, venlafaxine acts like an SSRI at low doses, but at 150 mg daily and above, it has a significant effect on norepinephrine reuptake. Duloxetine affects serotonin and norepinephrine reuptake at all doses. Similar to SSRIs, SNRIs should be started at lower doses and titrated ...
... dose dependent. For example, venlafaxine acts like an SSRI at low doses, but at 150 mg daily and above, it has a significant effect on norepinephrine reuptake. Duloxetine affects serotonin and norepinephrine reuptake at all doses. Similar to SSRIs, SNRIs should be started at lower doses and titrated ...
Drugs - The Ramirez Group
... Stimulation of dopamine release by cocaine, heroin, amphetamine, ritalin, adderall, and modafinil cause a homeostatic decrease in dopamine receptors. Only thing known to stimulate dopamine and INCREASE dopamine receptors: ...
... Stimulation of dopamine release by cocaine, heroin, amphetamine, ritalin, adderall, and modafinil cause a homeostatic decrease in dopamine receptors. Only thing known to stimulate dopamine and INCREASE dopamine receptors: ...
DUCURS poster 26
... We successfully developed and employed an HPLC assay to mouse brain catecholamines in a PD study. However, our curre findings do not indicate a significant PD interaction between bup and sertraline, and further studies are needed to fully investigate ...
... We successfully developed and employed an HPLC assay to mouse brain catecholamines in a PD study. However, our curre findings do not indicate a significant PD interaction between bup and sertraline, and further studies are needed to fully investigate ...
Drugs Affecting the Gastrointestinal System and Nutrition
... Uses: long-term therapy for PUD Action: acts locally binding directly to the surface of the ulcer. Note: not used as often due to short-term action and multiple daily dosing. ...
... Uses: long-term therapy for PUD Action: acts locally binding directly to the surface of the ulcer. Note: not used as often due to short-term action and multiple daily dosing. ...
Demographic Differences in the Misuse and Abuse of Oxycodone
... • By history, this patient ingested the largest dose reported. • First pass metabolism is reduced at higher dosages, thus bioavailability increases in overdose.1 ...
... • By history, this patient ingested the largest dose reported. • First pass metabolism is reduced at higher dosages, thus bioavailability increases in overdose.1 ...
Psychopharm Dr Tim Lau 2010_compressed
... May be arrhythmogenic in cardiac patients Arrhythmias identified include isolated PVC's, ventricular couplets, and in 2 patients short episodes (3 to 4 beats) of ventricular tachycardia ...
... May be arrhythmogenic in cardiac patients Arrhythmias identified include isolated PVC's, ventricular couplets, and in 2 patients short episodes (3 to 4 beats) of ventricular tachycardia ...
![Symbyax (Zyprexa [olanzapine] and Prozac [fluoxetine] combination)](http://s1.studyres.com/store/data/008004324_1-4687ab11684bc08b6291bceb18fec16a-300x300.png)
Symbyax (Zyprexa [olanzapine] and Prozac [fluoxetine] combination)
... ated with second-generation antipsychotics, such as Zyprexa in Symbyax, is significantly lower than with conventional antipsychotics. In rare cases, however, Prozac has been associated with TD. It is too early to determine whether the combination of Zyprexa and Prozac may increase the incidence of T ...
... ated with second-generation antipsychotics, such as Zyprexa in Symbyax, is significantly lower than with conventional antipsychotics. In rare cases, however, Prozac has been associated with TD. It is too early to determine whether the combination of Zyprexa and Prozac may increase the incidence of T ...
hyperthermia - Calgary Emergency Medicine
... Serotonin Syndrome vs. NMS Differentiation important b/c different therapies – using wrong drug may be fatal At least 12 case reports of pts presenting with MDMA –related hyperpyrexia that fit diagnostic criteria for Serotonin syndrome Several have overlapping clinical features ...
... Serotonin Syndrome vs. NMS Differentiation important b/c different therapies – using wrong drug may be fatal At least 12 case reports of pts presenting with MDMA –related hyperpyrexia that fit diagnostic criteria for Serotonin syndrome Several have overlapping clinical features ...
Psychiatric Medication - integratedservice.org
... • Be familiar with commonly prescribed psychiatric medications, intended benefits, and how they work • Be familiar with common side effects, risks, and contraindications for each medication • Recognize signs of relapse or non-adherence to ...
... • Be familiar with commonly prescribed psychiatric medications, intended benefits, and how they work • Be familiar with common side effects, risks, and contraindications for each medication • Recognize signs of relapse or non-adherence to ...
Drugs of Abuse
... • MDMA has several acute toxic effects, in particular hyperthermia, which along with dehydration, may be fatal. • Other complications include serotonin syndrome (mental status change, autonomic hyperactivity, and neuromuscular abnormalities, and seizures). ...
... • MDMA has several acute toxic effects, in particular hyperthermia, which along with dehydration, may be fatal. • Other complications include serotonin syndrome (mental status change, autonomic hyperactivity, and neuromuscular abnormalities, and seizures). ...
Psychotropic Agents Unit 1
... ◦ ETOH, anesthetics, MAO inhibitors, antihistamines, TCA’s, narcotics, barbiturates ◦ Caffeine and smoking interfere with desired effect ...
... ◦ ETOH, anesthetics, MAO inhibitors, antihistamines, TCA’s, narcotics, barbiturates ◦ Caffeine and smoking interfere with desired effect ...
An analysis of drug induced Stevens-Johnson syndrome
... PATEL et al: DRUG INDUCED STEVENS-JOHNSON SYNDROME ...
... PATEL et al: DRUG INDUCED STEVENS-JOHNSON SYNDROME ...
Ecstasy info
... been administered to human volunteers in double-blind placebocontrolled trials, although most findings are based upon recreational MDMA users. The 'massive' boost in neurotransmitter activity can generate intense feelings of elation and pleasure, also hyperactivity and hyperthermia. This psychophysi ...
... been administered to human volunteers in double-blind placebocontrolled trials, although most findings are based upon recreational MDMA users. The 'massive' boost in neurotransmitter activity can generate intense feelings of elation and pleasure, also hyperactivity and hyperthermia. This psychophysi ...
schizophrenia
... Blocks reuptake of NE and 5HT very widely used fairly significant side effects ◦ mainly because they block ACh receptors blurred vision, dry mouth, urinary retention, irregular heart rate, constipation, sexual dysfunction, ...
... Blocks reuptake of NE and 5HT very widely used fairly significant side effects ◦ mainly because they block ACh receptors blurred vision, dry mouth, urinary retention, irregular heart rate, constipation, sexual dysfunction, ...
Antidepressant Agents
... • It can block 5-HT2 and α2 receptors. It is sedative due to its antihistaminic activity, but has no atropinelike actions. It does not interfer with sexual activity. Increased appetite and weight gain can occur. ...
... • It can block 5-HT2 and α2 receptors. It is sedative due to its antihistaminic activity, but has no atropinelike actions. It does not interfer with sexual activity. Increased appetite and weight gain can occur. ...
Serotonin syndrome
Serotonin syndrome is a potential symptom of any number of life-threatening drug interactions which may follow therapeutic drug use, combination, overdose of particular drugs, or the recreational use of certain drugs. Serotonin syndrome is not an idiopathic drug reaction; it is a predictable consequence of excess serotonin on the CNS and/or peripheral nervous system. For this reason, some experts strongly prefer the terms serotonin toxicity or serotonin toxidrome which more accurately reflect that it is a form of poisoning. Other names include serotonin sickness, serotonin storm, serotonin poisoning, hyperserotonemia, or serotonergic syndrome.Excessive levels of serotonin produce a spectrum of specific symptoms including cognitive, autonomic, and somatic effects. Symptoms may range from barely perceptible to fatal. Numerous drugs and drug combinations have been reported to produce serotonin syndrome, though the exact mechanism is not well understood in many instances.Diagnosis includes observing symptoms and investigating patient history for causal factors (interacting drugs). The syndrome has a characteristic picture but can be mistaken for other illnesses in some people, particularly those with neuroleptic malignant syndrome. No laboratory tests can currently confirm the diagnosis. Hence it is diagnosed based on symptoms, disease course (that is, the progression of the disease) and the exclusion of other possible causes of the presenting symptoms.Treatment consists of discontinuing medications which may contribute and in moderate to severe cases administering a serotonin antagonist. An important adjunct treatment includes controlling agitation with benzodiazepine sedation. The high-profile case of Libby Zion, who is generally accepted to have died from serotonin syndrome, resulted in changes to graduate medical education in New York State.