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Lecture 9: Citric Acid Cycle/Fatty Acid Catabolism
Lecture 9: Citric Acid Cycle/Fatty Acid Catabolism

... oxaloacetate, labeling only the right side of drawing. But none of the label was released as CO2. Always the left carboxyl group is instead released as CO2, i.e., that from oxaloacetate. This was interpreted as proof that citrate is not in the cycle at all the labels would have been scrambled, and h ...
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... practitioners because of their high cholesterol content. The average intact egg contains about 210 mg of cholesterol, whereas the recommended intake of cholesterol is 300 mg. However, a study published in the Journal of the American Medical Association, in addition to several other studies, refute t ...
I can - Net Start Class
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... D. Enzymes are specific because of their shape. 2. Enzymes only work with specific substrates because each substrate— A. has a specific activation site for enzyme attachment B. can only use a specific ionic bond with the enzyme. C. destroys its specific enzyme. D. interferes with other substrates ar ...
Biochemistry –Second year, Coll
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... will be transported to the muscles; cardiac and skeletal where they are used foe fatty acids oxidation to produce the ATP. About 97 % of the body ΄s carnitine is predominant in the muscles. Disorders of Carnitine Deficiences and β-Oxidation Impairment: Carnitine deficiency which may be primary and ...
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Studies on the Reactions of the Krebs Citric Acid Cycle in Tumor

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Browning - University of San Diego Home Pages

... Maillard  reactions  take  place  between  sugars  like  glucose  and  amino  acids  that  are  free   or  part  of  proteins.  In  meat,  the  sugar  glucose  comes  primarily  from  the  breakdown  of   Copyright  ©  2016  Wiley,  I ...
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UG Curriculum

... macromolecules. Details on structure need not be emphasized. Discussion on metabolic processes should put emphasis on the overall change, interdependence and molecular turnover. While details of the steps may be given, the student should not be expected to memorise them. An introduction to biochemic ...
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Glycolysis



Glycolysis (from glycose, an older term for glucose + -lysis degradation) is the metabolic pathway that converts glucose C6H12O6, into pyruvate, CH3COCOO− + H+. The free energy released in this process is used to form the high-energy compounds ATP (adenosine triphosphate) and NADH (reduced nicotinamide adenine dinucleotide).Glycolysis is a determined sequence of ten enzyme-catalyzed reactions. The intermediates provide entry points to glycolysis. For example, most monosaccharides, such as fructose and galactose, can be converted to one of these intermediates. The intermediates may also be directly useful. For example, the intermediate dihydroxyacetone phosphate (DHAP) is a source of the glycerol that combines with fatty acids to form fat.Glycolysis is an oxygen independent metabolic pathway, meaning that it does not use molecular oxygen (i.e. atmospheric oxygen) for any of its reactions. However the products of glycolysis (pyruvate and NADH + H+) are sometimes disposed of using atmospheric oxygen. When molecular oxygen is used in the disposal of the products of glycolysis the process is usually referred to as aerobic, whereas if the disposal uses no oxygen the process is said to be anaerobic. Thus, glycolysis occurs, with variations, in nearly all organisms, both aerobic and anaerobic. The wide occurrence of glycolysis indicates that it is one of the most ancient metabolic pathways. Indeed, the reactions that constitute glycolysis and its parallel pathway, the pentose phosphate pathway, occur metal-catalyzed under the oxygen-free conditions of the Archean oceans, also in the absence of enzymes. Glycolysis could thus have originated from chemical constraints of the prebiotic world.Glycolysis occurs in most organisms in the cytosol of the cell. The most common type of glycolysis is the Embden–Meyerhof–Parnas (EMP pathway), which was discovered by Gustav Embden, Otto Meyerhof, and Jakub Karol Parnas. Glycolysis also refers to other pathways, such as the Entner–Doudoroff pathway and various heterofermentative and homofermentative pathways. However, the discussion here will be limited to the Embden–Meyerhof–Parnas pathway.The entire glycolysis pathway can be separated into two phases: The Preparatory Phase – in which ATP is consumed and is hence also known as the investment phase The Pay Off Phase – in which ATP is produced.↑ ↑ 2.0 2.1 ↑ ↑ ↑ ↑ ↑ ↑
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