Gene Section TYR (tyrosinase (oculocutaneous albinism IA)) Atlas of Genetics and Cytogenetics
... longevity of melanocytes, these cells are considered to have a greater mutagenic burden. This burden is also greater due to the position of melanocytes within the skin and their exposure to UV light. Tyrosinase enzymatic activity has been found to be associated with a better prognosis due to its ass ...
... longevity of melanocytes, these cells are considered to have a greater mutagenic burden. This burden is also greater due to the position of melanocytes within the skin and their exposure to UV light. Tyrosinase enzymatic activity has been found to be associated with a better prognosis due to its ass ...
42(5): 551-557. 2010 Insecticidal activities of essential oils from
... activity, was not detected in response to phosphate-limiting conditions when the AUG was mutated. Alkaline phosphatase expression and activity serve as phenotypic markers for activation of the pho regulon. Therefore, the pho regulon had not been induced in these cells, whereas normal up-regulation w ...
... activity, was not detected in response to phosphate-limiting conditions when the AUG was mutated. Alkaline phosphatase expression and activity serve as phenotypic markers for activation of the pho regulon. Therefore, the pho regulon had not been induced in these cells, whereas normal up-regulation w ...
energy - Bide Sport
... refers to a filtration method that is particularly gentle and also preserves the native microparticles. ...
... refers to a filtration method that is particularly gentle and also preserves the native microparticles. ...
Gene expression profiling of mice with genetically modified muscle
... into the cell, as well as different forms of hexokinase/glucokinase for the phosphorylation of glucose. There are two genes, GYS1 and GYS2, encoding glycogen synthase in both mouse and human genomes. To date, GYS2 is only known to be expressed in liver whereas GYS1 is expressed in skeletal muscle an ...
... into the cell, as well as different forms of hexokinase/glucokinase for the phosphorylation of glucose. There are two genes, GYS1 and GYS2, encoding glycogen synthase in both mouse and human genomes. To date, GYS2 is only known to be expressed in liver whereas GYS1 is expressed in skeletal muscle an ...
Reduced amino acid alphabets exhibit an improved sensitivity and
... Protein Data Bank (PDB), it is clear that the same protein fold may be generated by different amino acid sequences; in effect, the structure of proteins is more conserved than their sequences (Chothia and Lesk, 1986). In some cases, the sequences underlying similar structures show almost zero sequen ...
... Protein Data Bank (PDB), it is clear that the same protein fold may be generated by different amino acid sequences; in effect, the structure of proteins is more conserved than their sequences (Chothia and Lesk, 1986). In some cases, the sequences underlying similar structures show almost zero sequen ...
Human Gene Therapy : A Brief Overview of the Genetic
... insert genetic material at a specific site on chromosome 19 with near 100% certainty. Researchers believe that most people carry AAV which do not cause disease and do not provoke an immune response. Scientists have demonstrated the animal experiments using AAV to correct genetic defects.18 It is now ...
... insert genetic material at a specific site on chromosome 19 with near 100% certainty. Researchers believe that most people carry AAV which do not cause disease and do not provoke an immune response. Scientists have demonstrated the animal experiments using AAV to correct genetic defects.18 It is now ...
A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is
... enhancer of zeste and trithorax (SET) domain superfamily.3 RIZ is isolated by protein-protein interaction with the retinoblastoma tumor suppressor protein (Rb).1 Consistent with a potential role in the Rb pathway, RIZ may play an important role in the pathogenesis of human cancer. Interestingly, RIZ ...
... enhancer of zeste and trithorax (SET) domain superfamily.3 RIZ is isolated by protein-protein interaction with the retinoblastoma tumor suppressor protein (Rb).1 Consistent with a potential role in the Rb pathway, RIZ may play an important role in the pathogenesis of human cancer. Interestingly, RIZ ...
protein
... • A well-known example is insulin, the hormone regulating glucose metabolism in animals. ...
... • A well-known example is insulin, the hormone regulating glucose metabolism in animals. ...
SCit: web tools for protein side chain
... analysis has brought significant progress in the field of side chain positioning. Usually, the dependence of the conformation of one side chain on that of the backbone is analysed as a function of the f and y angle values of that amino acid (3–6). Due to the number of possible combinations of the f ...
... analysis has brought significant progress in the field of side chain positioning. Usually, the dependence of the conformation of one side chain on that of the backbone is analysed as a function of the f and y angle values of that amino acid (3–6). Due to the number of possible combinations of the f ...
Protein conformational changes induced by adsorption onto material
... unfolded. The biological role of nonfolded protein domains is also the focus of considerable work in structural biology [25]. The classic view of Langmuir isotherm for protein adsorption on material surfaces assumes that some interaction energy is reversibly available to form a protein-material comp ...
... unfolded. The biological role of nonfolded protein domains is also the focus of considerable work in structural biology [25]. The classic view of Langmuir isotherm for protein adsorption on material surfaces assumes that some interaction energy is reversibly available to form a protein-material comp ...
It Works! Shake™ Product Info Sheet
... What is It Works! Shake? It Works! Shake is clean, plant-based protein that will help you energize your workouts, build lean muscle mass, and support your healthy metabolism! With only 100 calories per serving, It Works! Shake provides 15 grams of protein in a proprietary blend of Yellow Pea and Org ...
... What is It Works! Shake? It Works! Shake is clean, plant-based protein that will help you energize your workouts, build lean muscle mass, and support your healthy metabolism! With only 100 calories per serving, It Works! Shake provides 15 grams of protein in a proprietary blend of Yellow Pea and Org ...
Measurements of translation initiation from all 64 codons in E. coli
... The translation of messenger RNA (mRNA) to protein is one of the fundamental processes in biology. Control of translation is critical to enable precision bioengineering. One key modulator of translation is the initiation or ‘start’ codon, which is the three mRNA nucleotides that bind to Nformylmethi ...
... The translation of messenger RNA (mRNA) to protein is one of the fundamental processes in biology. Control of translation is critical to enable precision bioengineering. One key modulator of translation is the initiation or ‘start’ codon, which is the three mRNA nucleotides that bind to Nformylmethi ...
Using virus-induced gene silencing to identify novel regulators of
... After two weeks in the growth chambers, gene silencing in some of the plants was evident by a change in phenotype. At this time, all plants were bombarded with GFP DNA. The vectors containing 1x GFP and 2x GFP DNA were first scraped off a plate into a flask with a 500 ml solution of LB medium with t ...
... After two weeks in the growth chambers, gene silencing in some of the plants was evident by a change in phenotype. At this time, all plants were bombarded with GFP DNA. The vectors containing 1x GFP and 2x GFP DNA were first scraped off a plate into a flask with a 500 ml solution of LB medium with t ...
Biochemical and Molecular Characterization of the Chicken
... homeobox gene, apterous, is required during embryogenesis for proper development of wing and haltere imaginal discs (Wilson, 1981; Cohen et al., 1992; Bourgouin et al., 1992). In addition to the LIM-homeodomain proteins, a number of small (10-30 kD) proteins that are comprised primarily of LIM domai ...
... homeobox gene, apterous, is required during embryogenesis for proper development of wing and haltere imaginal discs (Wilson, 1981; Cohen et al., 1992; Bourgouin et al., 1992). In addition to the LIM-homeodomain proteins, a number of small (10-30 kD) proteins that are comprised primarily of LIM domai ...
Nutritional Control of Growth and Development in Yeast
... of energy and as carbon-containing precursors of anabolic metabolism and biomass accumulation (Johnston and Carlson 1992). However, yeast cells consume glucose or fructose in preference to other mono-, di-, and trisaccharides, such as sucrose, raffinose, or trehalose, and prefer any fermentable carbo ...
... of energy and as carbon-containing precursors of anabolic metabolism and biomass accumulation (Johnston and Carlson 1992). However, yeast cells consume glucose or fructose in preference to other mono-, di-, and trisaccharides, such as sucrose, raffinose, or trehalose, and prefer any fermentable carbo ...
Benefits of being biased! - Indian Academy of Sciences
... Jakkur P.O. Box 6436, Bangalore 560 064, India ...
... Jakkur P.O. Box 6436, Bangalore 560 064, India ...
Molecular identification of three Arabidopsis thaliana mitochondrial
... transport activities observed in plant mitochondria and/or liposomes reconstituted with plant proteins of varying purity are yet to be associated with specific protein sequences. An example is the DIC (dicarboxylate carrier), which catalyses the transport of dicarboxylates (malate and succinate) in ...
... transport activities observed in plant mitochondria and/or liposomes reconstituted with plant proteins of varying purity are yet to be associated with specific protein sequences. An example is the DIC (dicarboxylate carrier), which catalyses the transport of dicarboxylates (malate and succinate) in ...
Homology among (βα) 8 Barrels: Implications for the Evolution of
... barrel-like enzymes, and used this to infer homology. The signi®cance of these ®ndings, and how likely they were to have arisen by chance, is dif®cult to assess. The SCOP protein structure database (Murzin et al., 1995) currently distinguishes 23 superfamilies of TIM barrel, where the members of a s ...
... barrel-like enzymes, and used this to infer homology. The signi®cance of these ®ndings, and how likely they were to have arisen by chance, is dif®cult to assess. The SCOP protein structure database (Murzin et al., 1995) currently distinguishes 23 superfamilies of TIM barrel, where the members of a s ...
New Insight into the Main Metabolic Regulation of Escherichia Coli
... concerns the metabolic regulation (Shimizu, 2013a). The enzymes which form the metabolic pathways are subject to multiple levels of regulation, where the enzyme level regulation and the transcriptional regulation by global regulators play important roles in the metabolic regulation (Matsuoka and Shi ...
... concerns the metabolic regulation (Shimizu, 2013a). The enzymes which form the metabolic pathways are subject to multiple levels of regulation, where the enzyme level regulation and the transcriptional regulation by global regulators play important roles in the metabolic regulation (Matsuoka and Shi ...
Journal of Molecular Microbiology and Biotechnology
... al., 1996]. They are biosynthesized by multimodular proteins termed non-ribosomal peptide synthetases (NRPS). Each elongation cycle in non-ribosomal peptide biosynthesis needs the cooperation of three basic domains. (1) A domain (adenylation domain) selects its cognate amino acid and generates an en ...
... al., 1996]. They are biosynthesized by multimodular proteins termed non-ribosomal peptide synthetases (NRPS). Each elongation cycle in non-ribosomal peptide biosynthesis needs the cooperation of three basic domains. (1) A domain (adenylation domain) selects its cognate amino acid and generates an en ...
Journal of Agricultural and Food Chemistry
... plants as well as in cereal grains. They are synthesized as secretory proteins (i.e., in the endoplasmatic reticulum of storage cells and are accumulated in the form of protein bodies). They differ from prolamins in respect to morphogenesis because they are formed in cotyledons and controlled by gen ...
... plants as well as in cereal grains. They are synthesized as secretory proteins (i.e., in the endoplasmatic reticulum of storage cells and are accumulated in the form of protein bodies). They differ from prolamins in respect to morphogenesis because they are formed in cotyledons and controlled by gen ...
Characterisation and functional properties of watermelon (Citrullus
... The Osborne fractions of watermelon seeds had minimum solubility in the pH range 3–5 (data not shown). Protein solubility increased markedly below pH 3 and above pH 5. The considerable increase in protein solubility in acidic and alkaline environments was attributed to a gain in net negative or posi ...
... The Osborne fractions of watermelon seeds had minimum solubility in the pH range 3–5 (data not shown). Protein solubility increased markedly below pH 3 and above pH 5. The considerable increase in protein solubility in acidic and alkaline environments was attributed to a gain in net negative or posi ...
Infectious Pancreatic Necrosis Virus genesig Standard Kit
... 3097 nucleotides long and encodes a 107kDa precursor protein made up of VP2, VP3 and VP4 from a single large open reading frame (ORF). VP2 and 3 are structural proteins while VP4 is a non-structural protease which cleaves this precursor polyprotein. A second ORF in this genome segment overlaps the N ...
... 3097 nucleotides long and encodes a 107kDa precursor protein made up of VP2, VP3 and VP4 from a single large open reading frame (ORF). VP2 and 3 are structural proteins while VP4 is a non-structural protease which cleaves this precursor polyprotein. A second ORF in this genome segment overlaps the N ...
Supporting information. Rat urinary glycoprotein identified from
... association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation ...
... association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation ...
Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as transfer RNA (tRNA) or small nuclear RNA (snRNA) genes, the product is a functional RNA.The process of gene expression is used by all known life - eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses - to generate the macromolecular machinery for life.Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene regulation may also serve as a substrate for evolutionary change, since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in a cell or in a multicellular organism.In genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenotype, i.e. observable trait. The genetic code stored in DNA is ""interpreted"" by gene expression, and the properties of the expression give rise to the organism's phenotype. Such phenotypes are often expressed by the synthesis of proteins that control the organism's shape, or that act as enzymes catalysing specific metabolic pathways characterising the organism.