Lecture1cont
... Why Bio Informatics ? (cont.) • A more global view of experimental design. (from “one scientist = one gene/protein/disease” paradigm to whole organism consideration). • Data mining - functional/structural information is important for studying the molecular basis of diseases, diagnostics, developing ...
... Why Bio Informatics ? (cont.) • A more global view of experimental design. (from “one scientist = one gene/protein/disease” paradigm to whole organism consideration). • Data mining - functional/structural information is important for studying the molecular basis of diseases, diagnostics, developing ...
Document
... Growth and division genes of bacteria are regulated genes. Their expression is controlled by the needs of the cell as it responds to its environment with the goal of increasing in mass and dividing. Genes that generally are continuously expressed are constitutive genes (housekeeping genes). Examples ...
... Growth and division genes of bacteria are regulated genes. Their expression is controlled by the needs of the cell as it responds to its environment with the goal of increasing in mass and dividing. Genes that generally are continuously expressed are constitutive genes (housekeeping genes). Examples ...
supplementary figures
... to PVDF membranes for Western blotting using the indicated antibodies. ß-actin was used to control equal sample loading. Densitometer readings facilitated the comparison of relative protein expression levels with solvent treated control (which was set as “1”). b. After 24 h, the mRNA was purified, r ...
... to PVDF membranes for Western blotting using the indicated antibodies. ß-actin was used to control equal sample loading. Densitometer readings facilitated the comparison of relative protein expression levels with solvent treated control (which was set as “1”). b. After 24 h, the mRNA was purified, r ...
Chapter 4
... controlled by one promoter and transcribed as polycistronic mRNA and encode multiple gene products ...
... controlled by one promoter and transcribed as polycistronic mRNA and encode multiple gene products ...
DNAInternet webquest
... How many complete molecules of DNA do you begin with in DNA replication? _________________ How many DNA molecules do you end up with? ________________________ Is the new DNA molecules completely new? Explain. _____________________________________ ...
... How many complete molecules of DNA do you begin with in DNA replication? _________________ How many DNA molecules do you end up with? ________________________ Is the new DNA molecules completely new? Explain. _____________________________________ ...
RNA-catalysed nucleotide synthesis
... measure of its catalytic efficiency Kcat = Vmax/[E]T Number of rxn processes each active site catalyzes per unit time When [S]<
... measure of its catalytic efficiency Kcat = Vmax/[E]T Number of rxn processes each active site catalyzes per unit time When [S]<
Slide 1
... Evolutionary Effects of Developmental Genes Heterochrony -An evolutionary change in the rate or timing of developmental events. ...
... Evolutionary Effects of Developmental Genes Heterochrony -An evolutionary change in the rate or timing of developmental events. ...
Nucleic Acid Notes
... • Since shape is determined by amino acid sequence; changing sequence changes 3D shape • EX: Sickle cell anemia mutation changes one amino acid in the sequence (glu → ala) Abnormal hemoglobin molecules crystallize; cause blood cells to become sickle shaped ...
... • Since shape is determined by amino acid sequence; changing sequence changes 3D shape • EX: Sickle cell anemia mutation changes one amino acid in the sequence (glu → ala) Abnormal hemoglobin molecules crystallize; cause blood cells to become sickle shaped ...
BIO 245: Principles of Genetics Course description BIO 245
... locations of genes. o Objective 1C: To identify the parts, structure, and dimensions of DNA molecules, RNA molecules, and chromosomes, and be able to categorize DNA as well as describe how DNA is stored. o Objective 1D: To accurately diagram and describe the processes of replication, transcription, ...
... locations of genes. o Objective 1C: To identify the parts, structure, and dimensions of DNA molecules, RNA molecules, and chromosomes, and be able to categorize DNA as well as describe how DNA is stored. o Objective 1D: To accurately diagram and describe the processes of replication, transcription, ...
File
... DNA codes for Proteins (and sometimes RNA) • The sequence of _______________________________ in DNA codes for proteins!!!! – Order of ____________________ ______________________ – Central to cell function and life • Tells the cell what to do, what to produce, and when to do it!!! DNA Between Organis ...
... DNA codes for Proteins (and sometimes RNA) • The sequence of _______________________________ in DNA codes for proteins!!!! – Order of ____________________ ______________________ – Central to cell function and life • Tells the cell what to do, what to produce, and when to do it!!! DNA Between Organis ...
FUNCTIONS OF CELL ORGANELLES
... Nucleus contains the biochemical processes involved in the Replication of DNA before mitosis. Involved in the DNA repair. Transcription of DNA – RNA synthesis. Translation of DNA- Protein synthesis. NUCLEOLUS- involved in the processing of rRNA and ribosomal units ...
... Nucleus contains the biochemical processes involved in the Replication of DNA before mitosis. Involved in the DNA repair. Transcription of DNA – RNA synthesis. Translation of DNA- Protein synthesis. NUCLEOLUS- involved in the processing of rRNA and ribosomal units ...
Eukaryotic transcriptional control
... Chromatin-remodeling complexes in eukaryotes (ySwi/Snf; hSwi/Snf; hACF; RSF; etc) all contain a helicase/ATPase component to disrupt interactions between base-paired nucleic acids or between nucleic acids and ...
... Chromatin-remodeling complexes in eukaryotes (ySwi/Snf; hSwi/Snf; hACF; RSF; etc) all contain a helicase/ATPase component to disrupt interactions between base-paired nucleic acids or between nucleic acids and ...
functions of cell organelles
... Nucleus contains the biochemical processes involved in the Replication of DNA before mitosis. Involved in the DNA repair. Transcription of DNA – RNA synthesis. Translation of DNA- Protein synthesis. NUCLEOLUS- involved in the processing of rRNA and ribosomal units ...
... Nucleus contains the biochemical processes involved in the Replication of DNA before mitosis. Involved in the DNA repair. Transcription of DNA – RNA synthesis. Translation of DNA- Protein synthesis. NUCLEOLUS- involved in the processing of rRNA and ribosomal units ...
PPT presentation
... translated from mRNA in ribosomes sequence of amino acids (20 AAs) coded by codon (triplet of nucleotides) genetic code ...
... translated from mRNA in ribosomes sequence of amino acids (20 AAs) coded by codon (triplet of nucleotides) genetic code ...
RNA
... • Genetic messages can be decoded by copying part of the nucleotide sequence from DNA into RNA. • RNA contains coded information for making proteins. ...
... • Genetic messages can be decoded by copying part of the nucleotide sequence from DNA into RNA. • RNA contains coded information for making proteins. ...
MPS1 Antibody / Metallopan-stimulin 1 (R32561)
... RPS27 gene. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 4 ...
... RPS27 gene. Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 4 ...
Lecture 27
... •RNA processing occurs by a variety of mechanisms to convert a primary transcript into a final function RNA product •Eukaryotic pre-mRNAs are capped, polyadenylated, and spliced to yield one or more mature mRNAs before transport to the cytoplasm. These processes are coupled in the nucleus so that on ...
... •RNA processing occurs by a variety of mechanisms to convert a primary transcript into a final function RNA product •Eukaryotic pre-mRNAs are capped, polyadenylated, and spliced to yield one or more mature mRNAs before transport to the cytoplasm. These processes are coupled in the nucleus so that on ...
Chapter 17 (Oct 23, 27, 28)
... (a) An mRNA molecule is generally translated simultaneously by several ribosomes in clusters called polyribosomes. ...
... (a) An mRNA molecule is generally translated simultaneously by several ribosomes in clusters called polyribosomes. ...
3D modelling activity
... * RNA polymerase binds to a promoter sequence and transcribes the DNA into RNA until reaches a transcription stop sequence. ...
... * RNA polymerase binds to a promoter sequence and transcribes the DNA into RNA until reaches a transcription stop sequence. ...
Name: Date: Block:___ Background: Proteins are the molecules that
... Name: ____________________________________ Date: _________________ Block:___ Background: Proteins are the molecules that carry out most of the cell’s day-to-day functions. While the DNA in the nucleus is "the boss" and controls the activities of the cell, it is the proteins that "do the work." In th ...
... Name: ____________________________________ Date: _________________ Block:___ Background: Proteins are the molecules that carry out most of the cell’s day-to-day functions. While the DNA in the nucleus is "the boss" and controls the activities of the cell, it is the proteins that "do the work." In th ...
Lecture 7 Oct 10th
... specific region of DNA, in order to produce enough DNA to be adequately tested. • In order to use PCR, one must already know the exact sequences which flank (lie on either side of) both ends of a given region of interest in DNA (may be a gene or any sequence). One need not know the DNA sequence in-b ...
... specific region of DNA, in order to produce enough DNA to be adequately tested. • In order to use PCR, one must already know the exact sequences which flank (lie on either side of) both ends of a given region of interest in DNA (may be a gene or any sequence). One need not know the DNA sequence in-b ...
Slides
... Quantitatively characterize interactions of network elements; Predict the function of genes in biological networks. ...
... Quantitatively characterize interactions of network elements; Predict the function of genes in biological networks. ...
Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as transfer RNA (tRNA) or small nuclear RNA (snRNA) genes, the product is a functional RNA.The process of gene expression is used by all known life - eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses - to generate the macromolecular machinery for life.Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene regulation may also serve as a substrate for evolutionary change, since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in a cell or in a multicellular organism.In genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenotype, i.e. observable trait. The genetic code stored in DNA is ""interpreted"" by gene expression, and the properties of the expression give rise to the organism's phenotype. Such phenotypes are often expressed by the synthesis of proteins that control the organism's shape, or that act as enzymes catalysing specific metabolic pathways characterising the organism.