Desert hedgehog is a mammal-specific gene expressed during testicular and ovarian
... partner Sox9 [20-22]. Dhh-null male mice are sex reversed [21,23], their gonads are small and devoid of sperm and the mice develop as phenotypic females due to a lack of male steroid hormone production [20,21]. Leydig cell numbers are dramatically decreased in the Dhh null gonad, but are not entirel ...
... partner Sox9 [20-22]. Dhh-null male mice are sex reversed [21,23], their gonads are small and devoid of sperm and the mice develop as phenotypic females due to a lack of male steroid hormone production [20,21]. Leydig cell numbers are dramatically decreased in the Dhh null gonad, but are not entirel ...
Desert hedgehogis a mammal-specific gene expressed during
... partner Sox9 [20-22]. Dhh-null male mice are sex reversed [21,23], their gonads are small and devoid of sperm and the mice develop as phenotypic females due to a lack of male steroid hormone production [20,21]. Leydig cell numbers are dramatically decreased in the Dhh null gonad, but are not entirel ...
... partner Sox9 [20-22]. Dhh-null male mice are sex reversed [21,23], their gonads are small and devoid of sperm and the mice develop as phenotypic females due to a lack of male steroid hormone production [20,21]. Leydig cell numbers are dramatically decreased in the Dhh null gonad, but are not entirel ...
Safety assessment - Federal Register of Legislation
... In the Northern Hemisphere, corn plants are susceptible to damage from feeding by a Coleopteran insect pest, corn rootworm (Diabrotica spp.). The Applicant has previously developed two separate genetically modified (GM) inbred lines, one containing a trait that confers protection to the corn rootwor ...
... In the Northern Hemisphere, corn plants are susceptible to damage from feeding by a Coleopteran insect pest, corn rootworm (Diabrotica spp.). The Applicant has previously developed two separate genetically modified (GM) inbred lines, one containing a trait that confers protection to the corn rootwor ...
Gene Section MUC4 (mucin 4, cell surface associated) in Oncology and Haematology
... PEA3 and Med-1) was found within that promoter. The distal promoter is flanked by a TATA box located at 2672/-2668 and three transcriptional initiation sites at 2603, -2604 and -2605. Responsive regions and ciselements for transcription factors involved in Protein Kinase A, Protein Kinase C, cAMP si ...
... PEA3 and Med-1) was found within that promoter. The distal promoter is flanked by a TATA box located at 2672/-2668 and three transcriptional initiation sites at 2603, -2604 and -2605. Responsive regions and ciselements for transcription factors involved in Protein Kinase A, Protein Kinase C, cAMP si ...
Aspects of Reductive Explanation in Biological Science: Intrinsicality
... to distinguish because they can introduce qualifications about intrinsicality. For example, a qualified fundamentality might pick out biochemical properties as explanatory of cell properties, which implies that biochemical properties outside of the cell (i.e. extrinsic) are fundamental and that othe ...
... to distinguish because they can introduce qualifications about intrinsicality. For example, a qualified fundamentality might pick out biochemical properties as explanatory of cell properties, which implies that biochemical properties outside of the cell (i.e. extrinsic) are fundamental and that othe ...
LNBI 9043 - Lupin Allergy: Uncovering Structural Features and
... cupin-like structure, γ-conglutin (basic 7S-globulin), displays tetrameric structure integrated by two different disulphide-linked monomers. In contrast, δ-conglutin (2S sulphur-rich albumin) contains 2 disulphide-linked proteins with the typical cysteinerich prolamin structure [3]. Sweet lupin seed ...
... cupin-like structure, γ-conglutin (basic 7S-globulin), displays tetrameric structure integrated by two different disulphide-linked monomers. In contrast, δ-conglutin (2S sulphur-rich albumin) contains 2 disulphide-linked proteins with the typical cysteinerich prolamin structure [3]. Sweet lupin seed ...
PPT - Altogen Biosystems
... 1. Plate 10,000 - 15,000 AGS cells per well in 0.5 ml of complete growth medium 12–24 hours prior to transfection 2. Wash with 1xPBS and add 0.5 ml of fresh growth medium 3. Prepare transfection complexes by mixing 40 µl of serum free medium, 5.5 µl of transfection reagent, and • 750 ng DNA (or mRNA ...
... 1. Plate 10,000 - 15,000 AGS cells per well in 0.5 ml of complete growth medium 12–24 hours prior to transfection 2. Wash with 1xPBS and add 0.5 ml of fresh growth medium 3. Prepare transfection complexes by mixing 40 µl of serum free medium, 5.5 µl of transfection reagent, and • 750 ng DNA (or mRNA ...
Pyruvate : NADP+ Oxidoreductase from the Mitochondrion of
... the earliest eukaryotic cells (Martin and Müller 1998). In principle, three alternative explanations could currently account for the distribution of PFO among eukaryotes and its evident correlation with the amitochondriate phenotype. The first possible explanation is that the host of mitochondrial ...
... the earliest eukaryotic cells (Martin and Müller 1998). In principle, three alternative explanations could currently account for the distribution of PFO among eukaryotes and its evident correlation with the amitochondriate phenotype. The first possible explanation is that the host of mitochondrial ...
Open the publication - UEF Electronic Publications
... cells and that genetics is a key element for understanding why all of us differ from each other. Characteristics of an organism, known as phenotype, are dependent not only on environment but also on unique heritable genetic information carried by organism, its genotype. Genetic information of an org ...
... cells and that genetics is a key element for understanding why all of us differ from each other. Characteristics of an organism, known as phenotype, are dependent not only on environment but also on unique heritable genetic information carried by organism, its genotype. Genetic information of an org ...
Multiple Sequence Motifs in the Rubisco Small
... Figure 1. Protein import of RbcS-tp:GFP and E1a-tp:GFP in wild-type and ppi2 mutant protoplasts. A, Sequences of RbcS-tp and E1a-tp. TP cleavage sites were predicted by TargetP (Emanuelsson et al., 2000) and indicated by arrowheads. B, Images of RbcStp:GFP and E1a-tp:GFP. Protoplasts from wild-type ...
... Figure 1. Protein import of RbcS-tp:GFP and E1a-tp:GFP in wild-type and ppi2 mutant protoplasts. A, Sequences of RbcS-tp and E1a-tp. TP cleavage sites were predicted by TargetP (Emanuelsson et al., 2000) and indicated by arrowheads. B, Images of RbcStp:GFP and E1a-tp:GFP. Protoplasts from wild-type ...
ppt for
... Population dynamics of piRNA and TE(transposable element) in Drosophila • Jian Lu and Andrew G. Clark, PNAS 2010 • Activities of a large number of retrotransposons are severely silenced by piRNAs. 1) quantified expression levels of 32 TE families 2) in ovaries of one wild-type and three piRNA ...
... Population dynamics of piRNA and TE(transposable element) in Drosophila • Jian Lu and Andrew G. Clark, PNAS 2010 • Activities of a large number of retrotransposons are severely silenced by piRNAs. 1) quantified expression levels of 32 TE families 2) in ovaries of one wild-type and three piRNA ...
Lactobacillus plantarum - UEF Electronic Publications
... Lactic acid bacteria (LAB) are a heterogeneous group of organisms found in a wide range of environmental niches due to their large adaptation capacity. They are responsible for the fermentation of many fermented food and feed products because they can transform sugars into organic acids and decrease ...
... Lactic acid bacteria (LAB) are a heterogeneous group of organisms found in a wide range of environmental niches due to their large adaptation capacity. They are responsible for the fermentation of many fermented food and feed products because they can transform sugars into organic acids and decrease ...
- VU Research Repository
... been discovered that yeast acclimatise more quickly to ethanol stress in the presence of low acetaldehyde concentrations; however, the biochemical processes underpinning this effect are unknown. The objective of this project was to identify the mechanisms associated with the acetaldehyde-mediated ad ...
... been discovered that yeast acclimatise more quickly to ethanol stress in the presence of low acetaldehyde concentrations; however, the biochemical processes underpinning this effect are unknown. The objective of this project was to identify the mechanisms associated with the acetaldehyde-mediated ad ...
Document
... are needed to see this picture. QuickTime™ and a TIFF (Uncompressed) decompressor are needed to see this picture. QuickTime™ and a TIFF (Uncompressed) decompressor are needed to see this picture. ...
... are needed to see this picture. QuickTime™ and a TIFF (Uncompressed) decompressor are needed to see this picture. QuickTime™ and a TIFF (Uncompressed) decompressor are needed to see this picture. ...
Glucose transporters (GLUT and SGLT)
... Glucose is a key fuel in mammals and an important metabolic substrate. It is obtained directly from the diet, principally following the hydrolysis of ingested disaccharides and polysaccharides, and by synthesis from other substrates in organs such as the liver. Glucose derived from the diet is trans ...
... Glucose is a key fuel in mammals and an important metabolic substrate. It is obtained directly from the diet, principally following the hydrolysis of ingested disaccharides and polysaccharides, and by synthesis from other substrates in organs such as the liver. Glucose derived from the diet is trans ...
Phosphate Groups Modifying Myelin Basic Proteins Are
... fractions differing in degree of compaction suggested that even the basic protein phosphate groups of primarily compacted myelin participated in this rapid exchange. Similar studies were carried out on the metabolism of radioactive amino acids incorporated into the peptide backbone of myelin basic p ...
... fractions differing in degree of compaction suggested that even the basic protein phosphate groups of primarily compacted myelin participated in this rapid exchange. Similar studies were carried out on the metabolism of radioactive amino acids incorporated into the peptide backbone of myelin basic p ...
USMLE Step 1 - Becker Professional Education
... of State Medical Boards (FSMB) and National Board of Medical Examiners® (NBME®). United States Medical Licensing Examination, USMLE, National Board of Medical Examiners, and NBME are registered trademarks of the National Board of Medical Examiners. The National Board of Medical Examiners does not sp ...
... of State Medical Boards (FSMB) and National Board of Medical Examiners® (NBME®). United States Medical Licensing Examination, USMLE, National Board of Medical Examiners, and NBME are registered trademarks of the National Board of Medical Examiners. The National Board of Medical Examiners does not sp ...
Inhibitors of HIV-1 Reverse Transcriptase—Associated
... the RNA template strand positions the DNA strand in the polymerase active site such that the RNase H domain localizes to carry out cleavages 13-17 nucleotides downstrHDP RI WKH ¶-RNA terminus [13,14]. The exact cleavage position may depend in part on the sequence of the RNA strand [14,16,17]. No ...
... the RNA template strand positions the DNA strand in the polymerase active site such that the RNase H domain localizes to carry out cleavages 13-17 nucleotides downstrHDP RI WKH ¶-RNA terminus [13,14]. The exact cleavage position may depend in part on the sequence of the RNA strand [14,16,17]. No ...
Inhibitors of HIV-1 Reverse Transcriptase—Associated
... the RNA template strand positions the DNA strand in the polymerase active site such that the RNase H domain localizes to carry out cleavages 13-17 nucleotides downstrHDP RI WKH ¶-RNA terminus [13,14]. The exact cleavage position may depend in part on the sequence of the RNA strand [14,16,17]. No ...
... the RNA template strand positions the DNA strand in the polymerase active site such that the RNase H domain localizes to carry out cleavages 13-17 nucleotides downstrHDP RI WKH ¶-RNA terminus [13,14]. The exact cleavage position may depend in part on the sequence of the RNA strand [14,16,17]. No ...
PDF
... has a predominantly S = 3 / 2 ground state which gives rise to an approx, g = 5 EPR signal [12]. This unusual property is thought to be related to the partial non-cysteinyl coordination to the cluster, a property not shared by the ferredoxin of the hyperthermophile T. litoralis (see Fig. 3). ...
... has a predominantly S = 3 / 2 ground state which gives rise to an approx, g = 5 EPR signal [12]. This unusual property is thought to be related to the partial non-cysteinyl coordination to the cluster, a property not shared by the ferredoxin of the hyperthermophile T. litoralis (see Fig. 3). ...
Nucleic acid vaccines against rickettsial diseases and methods of use
... This application is a continuation-in-part of Ser. No. 09/337,827, ?led Jun. 22, 1999 noW abandoned; Which is a divisional of Ser. No. 08/953,326, ?led Oct. 17, 1997, now US. Pat. No. 6,251,872; Which is a continuation-in-part of ...
... This application is a continuation-in-part of Ser. No. 09/337,827, ?led Jun. 22, 1999 noW abandoned; Which is a divisional of Ser. No. 08/953,326, ?led Oct. 17, 1997, now US. Pat. No. 6,251,872; Which is a continuation-in-part of ...
Prokaryotic proteins of antioxidant defense in Trichomonas vaginalis
... Oxygen has a unique molecular structure with unique electron configuration resulting from two unpaired electrons in ground state of O2 molecule (triplet oxygen). It readily accepts electrons generated by normal oxidative metabolism of the cell. Processes causing uncoupling of electron transport can ...
... Oxygen has a unique molecular structure with unique electron configuration resulting from two unpaired electrons in ground state of O2 molecule (triplet oxygen). It readily accepts electrons generated by normal oxidative metabolism of the cell. Processes causing uncoupling of electron transport can ...
Nucleic Acids Research
... conserved sequence falls between bases 477 and 526 which are approximately 130 to 180 nucleotides 5' to the ATG initiation codon. Whether this has significance with respect to promoter function will await Of deletion or site-directed mutagenesis analysis of these sequences. the 27 base changes that ...
... conserved sequence falls between bases 477 and 526 which are approximately 130 to 180 nucleotides 5' to the ATG initiation codon. Whether this has significance with respect to promoter function will await Of deletion or site-directed mutagenesis analysis of these sequences. the 27 base changes that ...
Origin of the catalytic activity of bovine seminal ribonuclease against
... N103K), b ) A(A19S L35M K37Q N103K), c ) A(T3S A19S K37Q N103K), d ) A(T3S A19S K37Q N103E), e ) A(T3S S15P A19S K31Q K37Q S59F T70S Y76N T78A S80H A96V N103E), f ) A(T3S A19S K37Q N103E), g ) A(T3S A19S K37Q Y76N S80R N103E), h1 ) A(T3S S16G T17S A19S A20S N34K L35M K37Q D38G A64T Y76N S80R A102V N ...
... N103K), b ) A(A19S L35M K37Q N103K), c ) A(T3S A19S K37Q N103K), d ) A(T3S A19S K37Q N103E), e ) A(T3S S15P A19S K31Q K37Q S59F T70S Y76N T78A S80H A96V N103E), f ) A(T3S A19S K37Q N103E), g ) A(T3S A19S K37Q Y76N S80R N103E), h1 ) A(T3S S16G T17S A19S A20S N34K L35M K37Q D38G A64T Y76N S80R A102V N ...
Locked Nucleic Acid (LNA™)
... When ordering an LNA™ oligonucleotide from Exiqon you can either design the sequence and LNA™ spiking pattern yourself or let Exiqon’s experts help you with the design. Design your own LNA™ oligonucleotide Incorporation of LNA™ in a sequence strongly affects the properties of the oligonucleotide and ...
... When ordering an LNA™ oligonucleotide from Exiqon you can either design the sequence and LNA™ spiking pattern yourself or let Exiqon’s experts help you with the design. Design your own LNA™ oligonucleotide Incorporation of LNA™ in a sequence strongly affects the properties of the oligonucleotide and ...
Gene expression
Gene expression is the process by which information from a gene is used in the synthesis of a functional gene product. These products are often proteins, but in non-protein coding genes such as transfer RNA (tRNA) or small nuclear RNA (snRNA) genes, the product is a functional RNA.The process of gene expression is used by all known life - eukaryotes (including multicellular organisms), prokaryotes (bacteria and archaea), and utilized by viruses - to generate the macromolecular machinery for life.Several steps in the gene expression process may be modulated, including the transcription, RNA splicing, translation, and post-translational modification of a protein. Gene regulation gives the cell control over structure and function, and is the basis for cellular differentiation, morphogenesis and the versatility and adaptability of any organism. Gene regulation may also serve as a substrate for evolutionary change, since control of the timing, location, and amount of gene expression can have a profound effect on the functions (actions) of the gene in a cell or in a multicellular organism.In genetics, gene expression is the most fundamental level at which the genotype gives rise to the phenotype, i.e. observable trait. The genetic code stored in DNA is ""interpreted"" by gene expression, and the properties of the expression give rise to the organism's phenotype. Such phenotypes are often expressed by the synthesis of proteins that control the organism's shape, or that act as enzymes catalysing specific metabolic pathways characterising the organism.