Full Text
... uncontrolled status epilepticus (Dravet et al., 2005; Ceulemans et al., 2012). Delayed language development, disruption of autonomic function, and motor and cognitive impairment are also associated with this disease. Seizure management includes treatment with benzodiazepines, valproate, and/or stiri ...
... uncontrolled status epilepticus (Dravet et al., 2005; Ceulemans et al., 2012). Delayed language development, disruption of autonomic function, and motor and cognitive impairment are also associated with this disease. Seizure management includes treatment with benzodiazepines, valproate, and/or stiri ...
Nocturnal Penile Tumescence
... of the Association of Professional Sleep Societies and published in sleep-suppressing medication (8,9), whereas buspiabstract form in Sleep Res 1991;20:91 and 1993;22:51. rone, at least in rats, may have REM sleep-suppressing ...
... of the Association of Professional Sleep Societies and published in sleep-suppressing medication (8,9), whereas buspiabstract form in Sleep Res 1991;20:91 and 1993;22:51. rone, at least in rats, may have REM sleep-suppressing ...
Guide for handling cytotoxic drugs and related waste
... Cytotoxic drugs are intended primarily for the treatment of cancer. They are known to be highly toxic to cells, principally through their action on cell reproduction. Many have proved to be carcinogens, mutagens or teratogens. Patients receiving therapeutic doses of these drugs have exhibited a long ...
... Cytotoxic drugs are intended primarily for the treatment of cancer. They are known to be highly toxic to cells, principally through their action on cell reproduction. Many have proved to be carcinogens, mutagens or teratogens. Patients receiving therapeutic doses of these drugs have exhibited a long ...
PrZOFRAN® Tablets, Oral Solution and Injection PrZOFRAN® ODT
... Ondansetron does not itself appear to induce or inhibit the cytochrome P450 drugmetabolizing enzyme system of the liver. Because ondansetron is metabolised by hepatic cytochrome P450 drug-metabolizing enzymes, inducers or inhibitors of these enzymes may change the clearance and, hence, the half-life ...
... Ondansetron does not itself appear to induce or inhibit the cytochrome P450 drugmetabolizing enzyme system of the liver. Because ondansetron is metabolised by hepatic cytochrome P450 drug-metabolizing enzymes, inducers or inhibitors of these enzymes may change the clearance and, hence, the half-life ...
Neuroscience of psychoactive substance use and dependence Neur
... and, in particular, the ethical implications of new biological intervention strategies. The various health and social problems associated with use of and dependence on tobacco, alcohol and illicit substances require greater attention by the public health community and appropriate policy responses ar ...
... and, in particular, the ethical implications of new biological intervention strategies. The various health and social problems associated with use of and dependence on tobacco, alcohol and illicit substances require greater attention by the public health community and appropriate policy responses ar ...
BIOLOGICAL EVALUATION OF OPIOIDS, STIMULANTS, AND
... 47 at UM (binding affinity to the µ, δ, and κ opioid receptors and GTPγS functional studies). Compounds were submitted primarily from academia; one compound was submitted from a governmental source. Figure 1 shows the continuing trend that the percentage of compounds originating from academia has be ...
... 47 at UM (binding affinity to the µ, δ, and κ opioid receptors and GTPγS functional studies). Compounds were submitted primarily from academia; one compound was submitted from a governmental source. Figure 1 shows the continuing trend that the percentage of compounds originating from academia has be ...
... constant level of ventilatory control [26]. Rectal temperature was monitored with a thermistor, kept within 1°C in each cat and ranged from 36.3–38.2°C among the animals. The trachea was cannulated and connected to a respiratory circuit. One femoral artery and vein were connected to an extracorporea ...
CLMM037 The use of syringes to administer flushes, feeds and
... The Medicines Act 1968 governs the supply and administration of all medicines in the UK. The majority of medicines prescribed in the UK are licensed under this Act. To remain licensed the medicine must be given in a licensed form, within a licensed dose range, by a licensed route and only for condit ...
... The Medicines Act 1968 governs the supply and administration of all medicines in the UK. The majority of medicines prescribed in the UK are licensed under this Act. To remain licensed the medicine must be given in a licensed form, within a licensed dose range, by a licensed route and only for condit ...
michelia champaca alba
... GITAM Institute of Pharmacy, GITAM University, Visakhapatnam- Andhra Pradesh, India-Pincode-530 045. Manuscript No: IJPRS/V3/I2/00265, Received On: 13/05/2014, Accepted On: 19/05/2014 ...
... GITAM Institute of Pharmacy, GITAM University, Visakhapatnam- Andhra Pradesh, India-Pincode-530 045. Manuscript No: IJPRS/V3/I2/00265, Received On: 13/05/2014, Accepted On: 19/05/2014 ...
Intra-Ventral Tegmental Area Injection of Rat Cocaine and
... Before experiments, all rats were habituated to the activity chambers and the injection procedure by daily sham injections for 3 days. The rats were placed in the photocell cages for 1 h, given a sham microinjection, and returned to the cages for another hour. On days when experimental data were col ...
... Before experiments, all rats were habituated to the activity chambers and the injection procedure by daily sham injections for 3 days. The rats were placed in the photocell cages for 1 h, given a sham microinjection, and returned to the cages for another hour. On days when experimental data were col ...
Martindale: The Complete Drug Reference
... Aspirin-sensitive asthmatic patients have developed reactions (rhinorrhoea, tightness of chest, wheezing, dyspnoea) when challenged with diclofenac in doses of 10 to 25 mg1 and the UK CSM has received a report of an aspirinsensitive patient who died from acute asthma 4 hours after a single 25-mg dos ...
... Aspirin-sensitive asthmatic patients have developed reactions (rhinorrhoea, tightness of chest, wheezing, dyspnoea) when challenged with diclofenac in doses of 10 to 25 mg1 and the UK CSM has received a report of an aspirinsensitive patient who died from acute asthma 4 hours after a single 25-mg dos ...
Plavix - Sanofi Canada
... due to clopidogrel. Because animal reproduction studies are not always predictive of a human response, PLAVIX should be used during pregnancy only if the potential benefits outweigh the potential risks to the fetus. Nursing Women: When given to lactating rats, clopidogrel caused a slight delay in th ...
... due to clopidogrel. Because animal reproduction studies are not always predictive of a human response, PLAVIX should be used during pregnancy only if the potential benefits outweigh the potential risks to the fetus. Nursing Women: When given to lactating rats, clopidogrel caused a slight delay in th ...
Actions of bufalin and cinobufotalin, two bufadienolides respectively
... legend of which contains the three equations. The goodness of fit in each case is highly significant and the slopes of the lines are not significantly different. The lCsovalues are shown in Table 1. From these it is seen that bufalin is almost seven times as potent as ouabain and cinobufotalin is le ...
... legend of which contains the three equations. The goodness of fit in each case is highly significant and the slopes of the lines are not significantly different. The lCsovalues are shown in Table 1. From these it is seen that bufalin is almost seven times as potent as ouabain and cinobufotalin is le ...
REVIEWS
... lesions either induced or exacerbated by IFN-α requiring discontinuation of IFN therapy for the eruption to subside; three similar cases were added in 1996,64-68 and additional cases were reported in 2000, 2005, and 2007.69-71 IFN-α was also found to induce a seronegative arthritis in two patients.7 ...
... lesions either induced or exacerbated by IFN-α requiring discontinuation of IFN therapy for the eruption to subside; three similar cases were added in 1996,64-68 and additional cases were reported in 2000, 2005, and 2007.69-71 IFN-α was also found to induce a seronegative arthritis in two patients.7 ...
B N ULLETI I N F O R M A T I O...
... cause amnesia—traits that make users vulnerable to sexual assault and other criminal acts. Users awakening or emerging from coma may exhibit extreme combativeness, a condition which is also observed among those in withdrawal from addiction to GHB and its analogs. GHB analogs are known to produce sid ...
... cause amnesia—traits that make users vulnerable to sexual assault and other criminal acts. Users awakening or emerging from coma may exhibit extreme combativeness, a condition which is also observed among those in withdrawal from addiction to GHB and its analogs. GHB analogs are known to produce sid ...
Methamphetamine Abuse
... There is no "off label" usage of drugs or products discussed in this course. You may find that both generic and trade names are used in courses produced by RN.com. The use of trade names does not indicate any preference of one trade named agent or company over another. Trade names are provided to en ...
... There is no "off label" usage of drugs or products discussed in this course. You may find that both generic and trade names are used in courses produced by RN.com. The use of trade names does not indicate any preference of one trade named agent or company over another. Trade names are provided to en ...
Stability and aerosolization of pressurized metered dose inhalers
... The ability of nanoparticles to disperse and form a physically stable suspension in propellant used is one of the major properties related to dose reproducibility in a suspension-type pMDI (Byron, 1992). Unstable suspensions can result in uncontrolled emitted dose and size characteristics, which lea ...
... The ability of nanoparticles to disperse and form a physically stable suspension in propellant used is one of the major properties related to dose reproducibility in a suspension-type pMDI (Byron, 1992). Unstable suspensions can result in uncontrolled emitted dose and size characteristics, which lea ...
Committee on Drugs 2001;108;1020 DOI: 10.1542/peds.108.4.1020
... Nutritional and drug-drug interactions are more likely than genetic differences in metabolism to contribute to toxicity at conventional doses of acetaminophen. Fasting is associated with increased acetaminophen hepatotoxicity in humans18 and animals19 apparently because of increased metabolism to NA ...
... Nutritional and drug-drug interactions are more likely than genetic differences in metabolism to contribute to toxicity at conventional doses of acetaminophen. Fasting is associated with increased acetaminophen hepatotoxicity in humans18 and animals19 apparently because of increased metabolism to NA ...
Biopharmaceutical considerations and in vitro
... A thesis submitted for the degree of Doctor of Philosophy University of Bath Department of Pharmacy and Pharmacology June 2014 ...
... A thesis submitted for the degree of Doctor of Philosophy University of Bath Department of Pharmacy and Pharmacology June 2014 ...
biodegradable implants with different drug release - diss.fu
... For biodegradable polyesters such as PLA, PGA and PLGA, the monomers are connected to each other by ester bonds. After water penetration into the polymer bulk the ester bonds are cleaved randomly by hydrolytic chain scission or hydrolysis. The bulk is eventually eroded through the bulk erosion mecha ...
... For biodegradable polyesters such as PLA, PGA and PLGA, the monomers are connected to each other by ester bonds. After water penetration into the polymer bulk the ester bonds are cleaved randomly by hydrolytic chain scission or hydrolysis. The bulk is eventually eroded through the bulk erosion mecha ...
DRUG ENCAPSULATION IN PECTIN HYDROGEL BEADS- A SYSTEMATIC STUDY OF
... gastrointestinal tract. Direct drug delivery to the colon is also more effective in the case of diseases such as ulcerative colitis, colorectal cancer and Crohn's disease. The active agents, such as proteins, antibiotics, nucleotides, etc, are encapsulated in high cross linked polymeric beads allowi ...
... gastrointestinal tract. Direct drug delivery to the colon is also more effective in the case of diseases such as ulcerative colitis, colorectal cancer and Crohn's disease. The active agents, such as proteins, antibiotics, nucleotides, etc, are encapsulated in high cross linked polymeric beads allowi ...
PUBLIC ASSESSMENT REPORT Decentralised Procedure
... rapidly absorbed. In recent studies the determination of blood concentration of the parent compound clopidogrel with sensitive detection methods like liquid chromatography tandem mass spectrometry could be achieved. The currently known active metabolite of clopidogrel is a thiol metabolite, which ha ...
... rapidly absorbed. In recent studies the determination of blood concentration of the parent compound clopidogrel with sensitive detection methods like liquid chromatography tandem mass spectrometry could be achieved. The currently known active metabolite of clopidogrel is a thiol metabolite, which ha ...
Ofloxacin as a Reference Marker in Hair of Various Colors
... measured hair concentrations of drug, given an equal dose, is affected by hair pigmentation (32--47). However, at least two reports have suggested that hair color does not play a role in the outcome of hair drug testing (48,49). These data are not necessarily contradictory, as the outcome of the dru ...
... measured hair concentrations of drug, given an equal dose, is affected by hair pigmentation (32--47). However, at least two reports have suggested that hair color does not play a role in the outcome of hair drug testing (48,49). These data are not necessarily contradictory, as the outcome of the dru ...
Procedures for Administering Injectable Drugs
... In line with the Joint British Diabetes Society guideline for managing diabetic ketoacidosis, and to cover existing practice on Torrington ICU, the following statement has been added to the Potassium Chloride monograph: “In adults, the rate of administration may be increased to 40mmol/hour in the ...
... In line with the Joint British Diabetes Society guideline for managing diabetic ketoacidosis, and to cover existing practice on Torrington ICU, the following statement has been added to the Potassium Chloride monograph: “In adults, the rate of administration may be increased to 40mmol/hour in the ...
Pharmacognosy
Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.