
Does High-Dose Buprenorphine Cause Respiratory Depression
... Particularly in regard to the management of buprenorphine overdoses, where contradictory results appeared. Indeed, in one case series, a rapid improvement of the patients using 0.4–0.8mg naloxone was reported,[38] whereas in a placebo-controlled study in volunteers, no effects of 1mg naloxone on mil ...
... Particularly in regard to the management of buprenorphine overdoses, where contradictory results appeared. Indeed, in one case series, a rapid improvement of the patients using 0.4–0.8mg naloxone was reported,[38] whereas in a placebo-controlled study in volunteers, no effects of 1mg naloxone on mil ...
the absorption, distribution, metabolism and excretion of rofecoxib, a
... pain and swelling of inflammation. Expression of COX-2 is stimulated by growth factors, cytokines, phorbol esters, and mitogens, but is inhibited by steroidal anti-inflammatories, e.g., glucocorticoids, which have little or no effect on COX-1 levels (reviewed by Vane and Botting, 1996; Donnelly and ...
... pain and swelling of inflammation. Expression of COX-2 is stimulated by growth factors, cytokines, phorbol esters, and mitogens, but is inhibited by steroidal anti-inflammatories, e.g., glucocorticoids, which have little or no effect on COX-1 levels (reviewed by Vane and Botting, 1996; Donnelly and ...
serotonin syndrome
... a medical emergency. Patients with a severe case of serotonin syndrome may have a body temperature > 41° C. Coma, metabolic acidosis, renal failure, rhabdomyolysis, and disseminated intravascular coagulation (DIC) may occur and all of this can develop very rapidly. The onset of the signs and sympto ...
... a medical emergency. Patients with a severe case of serotonin syndrome may have a body temperature > 41° C. Coma, metabolic acidosis, renal failure, rhabdomyolysis, and disseminated intravascular coagulation (DIC) may occur and all of this can develop very rapidly. The onset of the signs and sympto ...
09107sgp04
... transient effects that resolved with regular dosing. In dogs, heart rate increases were greater after co-administration than after salmeterol alone. ...
... transient effects that resolved with regular dosing. In dogs, heart rate increases were greater after co-administration than after salmeterol alone. ...
Assessment of zopiclone - World Health Organization
... to return to normal performance, which could occur e.g., in military operational settings. Zopiclone was the strongest sleep-inducing treatment of the four in terms of both subjective drowsiness and sleep recorded by EEG during 4-min eyes-closed rest periods, and its impairing effects in demanding p ...
... to return to normal performance, which could occur e.g., in military operational settings. Zopiclone was the strongest sleep-inducing treatment of the four in terms of both subjective drowsiness and sleep recorded by EEG during 4-min eyes-closed rest periods, and its impairing effects in demanding p ...
Aerosol delivery from spacers in wheezy infants: a daily life...
... 55) for the Nebuchamber, the nonDC-Babyhaler, and DC-Babyhaler respectively. Median dose delivery for the Nebuchamber was significantly higher than for the nonDC-Babyhaler (p=0.03) but lower than for the DCBabyhaler (p=0.005). The difference in dose delivery between nonDC-Babyhaler and DC-Babyhaler ...
... 55) for the Nebuchamber, the nonDC-Babyhaler, and DC-Babyhaler respectively. Median dose delivery for the Nebuchamber was significantly higher than for the nonDC-Babyhaler (p=0.03) but lower than for the DCBabyhaler (p=0.005). The difference in dose delivery between nonDC-Babyhaler and DC-Babyhaler ...
... proposed rule on dietary supplements containing ephedrine a:.kaloids. At the same, time FDA released the RAND Report. The RAND Report concluded that, based on available data, Ephedra Supplements are an efficacious treatment for moderate, short-term weight loss and that their use cannot be conclusive ...
Scientific Opinion on safety evaluation of Ephedra
... role in human nutrition as minerals and vitamins, which differ from them inter alia in being in general constituents of the normal diet and in being in many cases essential. This is particularly so in this specific case, where the botanicals and botanical preparations, or their main components, have ...
... role in human nutrition as minerals and vitamins, which differ from them inter alia in being in general constituents of the normal diet and in being in many cases essential. This is particularly so in this specific case, where the botanicals and botanical preparations, or their main components, have ...
Role of plant stanol ester - UEF Electronic Publications
... The effects of plant stanol esters or sterol esters on serum lipids and lipoprotein lipids, serum fatsoluble vitamins and carotenoids, serum cholesterol precursors as well as serum plant sterols and stanols were examined in mildly or moderately hypercholesterolemic men and women. Study I/II utilized ...
... The effects of plant stanol esters or sterol esters on serum lipids and lipoprotein lipids, serum fatsoluble vitamins and carotenoids, serum cholesterol precursors as well as serum plant sterols and stanols were examined in mildly or moderately hypercholesterolemic men and women. Study I/II utilized ...
Anabolic-androgenic steroid users in treatment
... Histories of a troubled childhood as well as current social disadvantage were both more frequent among the AAS users. Users also reported poor relationships with their parents and almost half of them had experienced physical or mental abuse. The AAS user’s experiences from school were mostly negativ ...
... Histories of a troubled childhood as well as current social disadvantage were both more frequent among the AAS users. Users also reported poor relationships with their parents and almost half of them had experienced physical or mental abuse. The AAS user’s experiences from school were mostly negativ ...
drug registration guidance document
... Added the statement “For products containing animal origin(s), please add this statement: This product contains substance(s) from animal origin” For products containing GINSENG… Added the statement “Safety on long term use has not been established” For products containing BEE POLLEN… Added the ...
... Added the statement “For products containing animal origin(s), please add this statement: This product contains substance(s) from animal origin” For products containing GINSENG… Added the statement “Safety on long term use has not been established” For products containing BEE POLLEN… Added the ...
AMERICAN ACADEMY OF PEDIATRICS Adolescents and Anabolic
... self-image must also be considered to be at risk. It is appropriate for pediatricians to inquire about anabolic steroid use during routine health maintenance visits because of the general health risks and the general distribution of the population at risk. Because recognition of the anabolic steroi ...
... self-image must also be considered to be at risk. It is appropriate for pediatricians to inquire about anabolic steroid use during routine health maintenance visits because of the general health risks and the general distribution of the population at risk. Because recognition of the anabolic steroi ...
... breathing could be due to several factors. The filter holder used for collection added about 20 mL to the inspiratory line. This causes a 10% loss of aerosol contained in the VT of 200 mL used by the ventilator. The dose collected from the NebuChamber by the ventilator was approximately 10% less tha ...
4. post-exposure prophylaxis for hiv
... (ATV/r), darunavir/ritonavir (DRV/r) and raltegravir (RAL) as ...
... (ATV/r), darunavir/ritonavir (DRV/r) and raltegravir (RAL) as ...
DANISH BIOTECH COMPANIES YEAR OF ESTABLISHMENT TYPE
... Researches and develops small molecule drug candidates within the fields of dermatology, cardiovascular diseases, antithrombotics, antibiotics, and bone metabolism. ...
... Researches and develops small molecule drug candidates within the fields of dermatology, cardiovascular diseases, antithrombotics, antibiotics, and bone metabolism. ...
Our Commitment to Legalizing Marijuana for Adults
... vomiting related to cancer chemotherapy and wasting (severe weight loss) associated with AIDS. Another FDA-approved medicine, Cesamet, contains the active ingredient Nabilone, which has a chemical structure similar to THC, the active ingredient of marijuana. And Sativex, an oromucosal spray approved ...
... vomiting related to cancer chemotherapy and wasting (severe weight loss) associated with AIDS. Another FDA-approved medicine, Cesamet, contains the active ingredient Nabilone, which has a chemical structure similar to THC, the active ingredient of marijuana. And Sativex, an oromucosal spray approved ...
Non-steroidal anti-inflammatory drugs (NSAIDs)
... A further reminder to physiotherapists of their responsibility under the legislation came in the form of a Letter to the Editor published in the members’ newsletter of the South Australian Branch of the Australian Physiotherapy Association (APA) newsletter, written by a representative of the Drugs a ...
... A further reminder to physiotherapists of their responsibility under the legislation came in the form of a Letter to the Editor published in the members’ newsletter of the South Australian Branch of the Australian Physiotherapy Association (APA) newsletter, written by a representative of the Drugs a ...
Piracetam - Rebound Health
... 21 U.S.C. § 321(ff)(1): Piracetam is not a vitamin, mineral, amino acid, herb or other botanical, or dietary substance for use by man to supplement the diet by increasing the total dietary intake. Further, piracetam is not a concentrate, metabolite, constituent, extract or combination of any such di ...
... 21 U.S.C. § 321(ff)(1): Piracetam is not a vitamin, mineral, amino acid, herb or other botanical, or dietary substance for use by man to supplement the diet by increasing the total dietary intake. Further, piracetam is not a concentrate, metabolite, constituent, extract or combination of any such di ...
Neuropharmacological Dissection of Placebo
... indicating that placebos activate endogenous opioid systems, thus producing placebo analgesia (Grevert et al., 1983; Fields and Levine, 1984; Levine and Gordon, 1984; Benedetti et al., 1995; Benedetti, 1996; Benedetti and Amanzio, 1997; Fields and Price, 1997). However, Gracely et al. (1983) showed ...
... indicating that placebos activate endogenous opioid systems, thus producing placebo analgesia (Grevert et al., 1983; Fields and Levine, 1984; Levine and Gordon, 1984; Benedetti et al., 1995; Benedetti, 1996; Benedetti and Amanzio, 1997; Fields and Price, 1997). However, Gracely et al. (1983) showed ...
View Full Article - PDF - International Research Journals
... isolates have increased MICs but are still susceptible (Sakoulas et al., 2004; Moise et al., 2007; Moise et al., 2008). vancomycin was <10% successful in the treatment of bacteremia caused by MRSA, with vancomycin MICs of 1–2 µg/mL, compared with 56% successful when the vancomycin MIC was <0.5 µg/mL ...
... isolates have increased MICs but are still susceptible (Sakoulas et al., 2004; Moise et al., 2007; Moise et al., 2008). vancomycin was <10% successful in the treatment of bacteremia caused by MRSA, with vancomycin MICs of 1–2 µg/mL, compared with 56% successful when the vancomycin MIC was <0.5 µg/mL ...
Comparison of Anti-Xa and Dilute Russell Viper Venom Time
... inhibits activated factor X (FXa). The drug has been used for stroke prevention in nonvalvular atrial fibrillation,1 as treatment for pulmonary embolism2 and symptomatic deep vein thrombosis,3 for anticoagulation in recent ST-segment elevation myocardial infarction,4 as thromboprophylaxis in Accepte ...
... inhibits activated factor X (FXa). The drug has been used for stroke prevention in nonvalvular atrial fibrillation,1 as treatment for pulmonary embolism2 and symptomatic deep vein thrombosis,3 for anticoagulation in recent ST-segment elevation myocardial infarction,4 as thromboprophylaxis in Accepte ...
Ministerstvo zdravotnictva SR k d. k. s04544-oKCLP-2012
... When oral warfarin therapy is started, it begins to inhibit the synthesis of clotting factors that have a short half-life (ie, factor VII and protein C) within 12 to 24 hours. However, warfarin does not achieve its full antithrombotic effect until 5 to 7 days after initiation.10,27 This is the tim ...
... When oral warfarin therapy is started, it begins to inhibit the synthesis of clotting factors that have a short half-life (ie, factor VII and protein C) within 12 to 24 hours. However, warfarin does not achieve its full antithrombotic effect until 5 to 7 days after initiation.10,27 This is the tim ...
Methadone-Associated Mortality
... serotonin/norepinephrine reuptake, and its very modest cost – all of which make it an appropriate choice for opioid therapy of pain and addiction (Savage, meeting presentation, 2003 [see www.samhsa.gov]; Lobert, 2003; Bruera, 2002; Payte, et al., 1994; Joseph and Woods, 1994; Kreek, 1992; Ettinger, ...
... serotonin/norepinephrine reuptake, and its very modest cost – all of which make it an appropriate choice for opioid therapy of pain and addiction (Savage, meeting presentation, 2003 [see www.samhsa.gov]; Lobert, 2003; Bruera, 2002; Payte, et al., 1994; Joseph and Woods, 1994; Kreek, 1992; Ettinger, ...
Pharmacognosy

Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.