ZOFRAN Tablets, Oral Solution and Injection PRODUCT MONOGRAPH
... cases of torsade de pointes have been reported in patients using ondansetron. Torsade de pointes is a polymorphic ventricular tachyarrhythmia. Generally, the risk of torsade de pointes increases with the magnitude of QTc prolongation produced by the drug. Torsade de pointes may be asymptomatic or ex ...
... cases of torsade de pointes have been reported in patients using ondansetron. Torsade de pointes is a polymorphic ventricular tachyarrhythmia. Generally, the risk of torsade de pointes increases with the magnitude of QTc prolongation produced by the drug. Torsade de pointes may be asymptomatic or ex ...
《药剂学》课程双语教学方法建设的工作进展
... applys to potent drug of low dose. USP method, 10 tablets are individually assayed for their content. The amount of active ingredient in each tablet lies within the range of 85% to 115% of the label claim(标示量) and the RSD is less than 6.0%. ...
... applys to potent drug of low dose. USP method, 10 tablets are individually assayed for their content. The amount of active ingredient in each tablet lies within the range of 85% to 115% of the label claim(标示量) and the RSD is less than 6.0%. ...
EFFICACY OF ALBENDAZOLE AGAINST EXPERIMENTAL INFECTIONS OF COENURUS CEREBRALIS IN GOATS.
... In Mozambique, goats are an important protein source and a major form of income for rural families. Goats are seriously affected by parasitic infections which are a major cause of morbidity and mortality and are considered to be an important constraint to goat production. One of these parasitic dise ...
... In Mozambique, goats are an important protein source and a major form of income for rural families. Goats are seriously affected by parasitic infections which are a major cause of morbidity and mortality and are considered to be an important constraint to goat production. One of these parasitic dise ...
Which neuroreceptors mediate the subjective effects of MDMA in
... intravenously) in 16 subjects, the 5-HT2 antagonist ketanserin (50 mg orally) in 14 subjects, and the D2 antagonist haloperidol (1.4 mg intravenously) in 14 subjects. Each of these studies used a double-blind placebo-controlled within-subject design and all subjects were examined under placebo, pret ...
... intravenously) in 16 subjects, the 5-HT2 antagonist ketanserin (50 mg orally) in 14 subjects, and the D2 antagonist haloperidol (1.4 mg intravenously) in 14 subjects. Each of these studies used a double-blind placebo-controlled within-subject design and all subjects were examined under placebo, pret ...
Effects of a Novel Cholecystokinin (CCK)
... MK-329 to be an effective inhibitor of CCK binding to pancreas and gallbladder tissues (IC50 = 81 and 45 pM, respectively), with a 1I,000-fold lower affinity for binding to cerebrocortical CCK (type B) receptors (6, 7). In addition, little affinity can be demonstrated for numerous other types of rec ...
... MK-329 to be an effective inhibitor of CCK binding to pancreas and gallbladder tissues (IC50 = 81 and 45 pM, respectively), with a 1I,000-fold lower affinity for binding to cerebrocortical CCK (type B) receptors (6, 7). In addition, little affinity can be demonstrated for numerous other types of rec ...
5 1 Prereview - World Health Organization
... of d-amphetamine available to the blood stream and therefore the CNS(2). Novascreen Biosciences Corporation screened lisdexamfetamine in radioligand-binding studies and found no activity (<50% inhibition at 10μM) for over sixty G-protein or ionchannel receptors, enzymes, or transporters. The pharmac ...
... of d-amphetamine available to the blood stream and therefore the CNS(2). Novascreen Biosciences Corporation screened lisdexamfetamine in radioligand-binding studies and found no activity (<50% inhibition at 10μM) for over sixty G-protein or ionchannel receptors, enzymes, or transporters. The pharmac ...
Alaris® PK Syringe Pump
... the Cp50 or Cp95 (the concentrations required to elicit a specified clinical effect in 50 or 95% of patients respectively). For an example see Ausems et al.5 During the 1990’s it was increasingly appreciated that after a change in plasma concentration there is a temporal delay in equilibration betwe ...
... the Cp50 or Cp95 (the concentrations required to elicit a specified clinical effect in 50 or 95% of patients respectively). For an example see Ausems et al.5 During the 1990’s it was increasingly appreciated that after a change in plasma concentration there is a temporal delay in equilibration betwe ...
Pharmacology of platelet inhibition in humans: implications of the
... ABSTRACT The current dispute over the effects of "low" vs "high"doses of aspirin should take into consideration the pharmacokinetics of this drug. In fact, different pharmaceutical formulations of aspirin may deliver little or no aspirin to the systemic blood. This was the case, for instance, in hea ...
... ABSTRACT The current dispute over the effects of "low" vs "high"doses of aspirin should take into consideration the pharmacokinetics of this drug. In fact, different pharmaceutical formulations of aspirin may deliver little or no aspirin to the systemic blood. This was the case, for instance, in hea ...
Nicotine and the Central Nervous System
... nary fashion, or two high-dose cigarettes in rapid succession, with deep inhalation (sufficient to produce nausea). In this series of studies, nicotine levels increased by approximately 5-6 ng/mL with the low-dose cigarette; by 20-25 ng/mL with the high-dose cigarette smoked in a normal manner; and ...
... nary fashion, or two high-dose cigarettes in rapid succession, with deep inhalation (sufficient to produce nausea). In this series of studies, nicotine levels increased by approximately 5-6 ng/mL with the low-dose cigarette; by 20-25 ng/mL with the high-dose cigarette smoked in a normal manner; and ...
Download CV
... Harada C, Harada T, Slusher BS, Yosida K, Matsuda H, Wada K. “N-acetylated-alpha-linked-acidic dipeptidase inhibitor has a neuroprotective effect on mouse retinal ganglion cells after pressure-induced ischemia.” Neuroscience Letters, 2000, 292(2):134-6 Shippenberg TS, Rea W, Slusher BS. “Modulation ...
... Harada C, Harada T, Slusher BS, Yosida K, Matsuda H, Wada K. “N-acetylated-alpha-linked-acidic dipeptidase inhibitor has a neuroprotective effect on mouse retinal ganglion cells after pressure-induced ischemia.” Neuroscience Letters, 2000, 292(2):134-6 Shippenberg TS, Rea W, Slusher BS. “Modulation ...
Drug Class Review on Constipation Drugs
... (IBS-C), or mixed—a combination of both (IBS-M), depending on the most prevalent bowel pattern. This sub-classification is determined by stool frequency, form, and passage. However, because the predominant symptom often changes over time, it is not uncommon for a patient to alternate between these I ...
... (IBS-C), or mixed—a combination of both (IBS-M), depending on the most prevalent bowel pattern. This sub-classification is determined by stool frequency, form, and passage. However, because the predominant symptom often changes over time, it is not uncommon for a patient to alternate between these I ...
The Science of Megestrol Acetate Delivery | SpringerLink
... of muscle mass and, to a lesser extent, adipose tissue. Etymologically, cachexia is derived from ‘kakos’ and ‘hexis’—Greek words meaning ‘bad condition’.[2] Although there are various definitions of cachexia in the medical literature, it commonly refers to an involuntary loss of approximately ≥5% of ...
... of muscle mass and, to a lesser extent, adipose tissue. Etymologically, cachexia is derived from ‘kakos’ and ‘hexis’—Greek words meaning ‘bad condition’.[2] Although there are various definitions of cachexia in the medical literature, it commonly refers to an involuntary loss of approximately ≥5% of ...
Active Transport of Fentanyl by the Blood-Brain Barrier1
... (EC75 for saturating the inward transport mechanism). Figure 2 shows that [3H]fentanyl was released from BBMECs at a faster rate when 10 mM cold fentanyl was present, consistent with its inhibition of a transporter directed inwardly. The ratio of the rate constants for passive diffusion (unsaturable ...
... (EC75 for saturating the inward transport mechanism). Figure 2 shows that [3H]fentanyl was released from BBMECs at a faster rate when 10 mM cold fentanyl was present, consistent with its inhibition of a transporter directed inwardly. The ratio of the rate constants for passive diffusion (unsaturable ...
11146027
... Hypertension and dyslipidemia may frequently coexist, and together have an increase in coronary heart disease related events. Combination therapy of rosuvastatin calcium and amlodipine besylate, effective for the control of hypertension by substantially reducing blood pressure and cholesterol levels ...
... Hypertension and dyslipidemia may frequently coexist, and together have an increase in coronary heart disease related events. Combination therapy of rosuvastatin calcium and amlodipine besylate, effective for the control of hypertension by substantially reducing blood pressure and cholesterol levels ...
KHAT (CATHA EDULIS) A CONTROVERSIAL PLANT: BLESSING
... In the context of the UNDCP study on illicit drug trends in Africa (UNDCP, 1999), field research was undertaken in Ethiopia in early 1998, confirming that the cultivation of khat is financially attractive and is spreading into new areas, apparently at the expense of traditional staple and cash crops ...
... In the context of the UNDCP study on illicit drug trends in Africa (UNDCP, 1999), field research was undertaken in Ethiopia in early 1998, confirming that the cultivation of khat is financially attractive and is spreading into new areas, apparently at the expense of traditional staple and cash crops ...
Dronabinol and Marijuana in HIV
... marijuana (3.95% THC 3 times daily) administered for 3 weeks were well tolerated and resulted in more weight gain than placebo administration,22 while having no negative impact on antiretroviral pharmacokinetics or immune function.21–24 Among current marijuana smokers, much higher acute doses of dro ...
... marijuana (3.95% THC 3 times daily) administered for 3 weeks were well tolerated and resulted in more weight gain than placebo administration,22 while having no negative impact on antiretroviral pharmacokinetics or immune function.21–24 Among current marijuana smokers, much higher acute doses of dro ...
Synephrine, Octopamine and Caffeine Health Risk
... approach within risk management. Such unauthorized products are therefore classified as a Type II risk to health. p-Synephrine and Caffeine Products providing 40 mg/day or less of p-synephrine plus 320 mg/day or less of caffeine, are classified as Type III, except in cases where the necessary cautio ...
... approach within risk management. Such unauthorized products are therefore classified as a Type II risk to health. p-Synephrine and Caffeine Products providing 40 mg/day or less of p-synephrine plus 320 mg/day or less of caffeine, are classified as Type III, except in cases where the necessary cautio ...
Analysis of submissions: Proposal to Classify
... The possibility of large numbers of BZP users presenting at hospitals with adverse effects; ...
... The possibility of large numbers of BZP users presenting at hospitals with adverse effects; ...
CHAPTER 2 REVIEW OF LITERATURE SECTION I: COCAINE
... predominant mode of ingestion of cocaine until 1860, when the drug was isolated by Albert Niemann. The leaves have also been steeped into teas and incorporated into beverages, such as Coca Cola (which no longer contains cocaine.) In the United States, cocaine was once an ingredient in many patented ...
... predominant mode of ingestion of cocaine until 1860, when the drug was isolated by Albert Niemann. The leaves have also been steeped into teas and incorporated into beverages, such as Coca Cola (which no longer contains cocaine.) In the United States, cocaine was once an ingredient in many patented ...
Pharmacokinetics of Erythromycin Ethylsuccinate
... concentrations after oral or intragastric administration. When given in combination with rifampin, erythromycin has synergistic bactericidal activity against this organism.3 Because no erythromycin formulations are approved for oral or intragastric administration to horses and because there have bee ...
... concentrations after oral or intragastric administration. When given in combination with rifampin, erythromycin has synergistic bactericidal activity against this organism.3 Because no erythromycin formulations are approved for oral or intragastric administration to horses and because there have bee ...
Cellulose, Chitosan, and Keratin Composite Materials. Controlled
... corresponding individual components. This, as noted earlier, further confirms that no chemical alterations occurred during the synthesis of these composites. Mechanical Properties. Although KER has been shown to induce controlled release of drug substances,5,8,9,13 its poor mechanical properties cont ...
... corresponding individual components. This, as noted earlier, further confirms that no chemical alterations occurred during the synthesis of these composites. Mechanical Properties. Although KER has been shown to induce controlled release of drug substances,5,8,9,13 its poor mechanical properties cont ...
ERLN-TB expert opinion on the use of the rapid molecular assays
... isolates as a laboratory tool in addition to standard drug susceptibility methods. The GTsl should not replace standard diagnostic methods and conventional drug susceptibility testing. However, based on limited evidence, the GTsl cannot at present be recommended for use directly on primary clinical ...
... isolates as a laboratory tool in addition to standard drug susceptibility methods. The GTsl should not replace standard diagnostic methods and conventional drug susceptibility testing. However, based on limited evidence, the GTsl cannot at present be recommended for use directly on primary clinical ...
Teschke2009_kava
... Ethnopharmacological relevance: Ethanolic and acetonic kava extracts have previously been causally related to rare hepatotoxicity observed in patients from Germany and Switzerland, but causality assess- Q2 ment was not performed in cases of patients having taken the traditional aqueous kava extracts ...
... Ethnopharmacological relevance: Ethanolic and acetonic kava extracts have previously been causally related to rare hepatotoxicity observed in patients from Germany and Switzerland, but causality assess- Q2 ment was not performed in cases of patients having taken the traditional aqueous kava extracts ...
Filed - Eastern District of California Blog
... The drug or other substance has a high potential for abuse. . . . . . 13 i. Acetaminophen (Tylenol). . . . . . . . . . . . . . . . . . . . . . . . . 13 ii. Dextromethorphan (Cough Medicine). . . . . . . . . . . . . . . . 14 iii. Acetylsalicylic acid (Aspirin).. . . . . . . . . . . . . . . . . . . . ...
... The drug or other substance has a high potential for abuse. . . . . . 13 i. Acetaminophen (Tylenol). . . . . . . . . . . . . . . . . . . . . . . . . 13 ii. Dextromethorphan (Cough Medicine). . . . . . . . . . . . . . . . 14 iii. Acetylsalicylic acid (Aspirin).. . . . . . . . . . . . . . . . . . . . ...
HOMEOPATHIC FAMILY MEDICINE - Homeopathic Educational
... As important as research is to knowing if something works or not, please know that just because there may not be formal studies published on the homeopathic treatment of a specific disease does NOT mean that homeopathy isn’t helpful in treating people who suffer from this ailment. In fact, because a ...
... As important as research is to knowing if something works or not, please know that just because there may not be formal studies published on the homeopathic treatment of a specific disease does NOT mean that homeopathy isn’t helpful in treating people who suffer from this ailment. In fact, because a ...
Pharmacognosy
Pharmacognosy is the study of medicinal drugs derived from plants or other natural sources. The American Society of Pharmacognosy defines pharmacognosy as ""the study of the physical, chemical, biochemical and biological properties of drugs, drug substances or potential drugs or drug substances of natural origin as well as the search for new drugs from natural sources.""It is also defined as the study of crude drugs.