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Unlocking Relationships with DNA
Unlocking Relationships with DNA

... time frames. In other words, it can determine ones descent from ancient populations, but it doesn’t help one find a great grandmother. Chart 1 illustrates the problems with trying to use DNA to trace ancestry through the female line. A third category of DNA is referred to as autosomal DNA. Autosomal ...
499 Med Chem Chap 6 problems
499 Med Chem Chap 6 problems

... 09) Which of the following statements is not true about DNA secondary structure? a. There is a minor groove and a major groove. b. A purine base pairs up with a pyrimidine base. c. The phosphate groups are positioned to the inside of the structure. d. The base pairs are stacked. 10) What non-covalen ...
DNA: The Genetic Material
DNA: The Genetic Material

... 2. Also, has regular diameter (~20 Angstroms = 20 Å) • [= width of two purine/pyrimidine nucleotide pairs!! = 2 strands.] ...
Purine-pyrimidine symmetry, determinative degree and DNA
Purine-pyrimidine symmetry, determinative degree and DNA

... nT 6= 0, nA 6= 0 3 (nT + nA ) nT − nA Leu,Asn,Tur,TERM The trinucleotide DNA can be listed in the similar, but more cumbersome way. The full DNA sequences consist of nucleotides of all four types and described by (9)-(10). The introduction of the determinative degree allows us to single out a kind o ...
2-5 DNA Cont. and Cell Cycle
2-5 DNA Cont. and Cell Cycle

Study Questions and Answers for Microbial Ecology Lecture 1. What
Study Questions and Answers for Microbial Ecology Lecture 1. What

... Biological, geological, and chemical processes that work together to interconvert an element into various chemical forms (controls the fate of an element), which influences how an element is transported through the environment. Prokaryotes carry out metabolic reactions that can alter the fate of an ...
7.3 Protein Synthesis
7.3 Protein Synthesis

... P-site and bonds by base pairing its anti-codon with the mRNA start codon (what is the start codon?) • Elongation – The second tRNA then comes into A-site and bonds to codon of mRNA – The two amino acids joined with peptide bond • Termination – ribosome continues reading mRNA until a STOP codon is r ...
Protein Synthesis 2013
Protein Synthesis 2013

... P-site and bonds by base pairing its anti-codon with the mRNA start codon (what is the start codon?) • Elongation – The second tRNA then comes into A-site and bonds to codon of mRNA – The two amino acids joined with peptide bond • Termination – ribosome continues reading mRNA until a STOP codon is r ...
6-Methoxyadenine Residue Forms a Watson
6-Methoxyadenine Residue Forms a Watson

... et al., 1998). To form such a pair with a cytosine residue, the adenine moiety must be in the imino form. The unmodi®ed adenine residue never adopts such a tautomer (Wolfenden, 1969). On the other hand, in the structures of N6-methoxyadenine derivatives (Fujii et al., 1990; Birnbaum et al., 1984), i ...
CHAPTER 12
CHAPTER 12

... during telophase, vesicles derived from the Golgi apparatus move along microtubules to the middle of the cell where they coalesce, producing a cell plate ...
No Slide Title
No Slide Title

... Know all the hydrogen bond donors and acceptors in the Watson-Crick base pairs How do donors and acceptors change when the enol form of the bases are found vs. the keto form? What base groups are found in the major and mi nor grooves? Be able to draw the Watson-Crick base pairs Understand Hoogsten p ...
This would be given at the end of the unit
This would be given at the end of the unit

... d. polymerase chain reaction 2. In Figure 13-1, between which nucleotides is the DNA cut? a. adenine and thymine b. cytosine and guanine c. thymine and cytosine d. adenine and guanine 3. To produce genetically engineered bacteria that make a human protein, which of the following steps does a scienti ...
EXERCISE 1: Fred Griffith and Transformation
EXERCISE 1: Fred Griffith and Transformation

... incredible diversity to be found among living things? Some scientists thought it must be a protein, because proteins are present in large quantities in the cell and carry on numerous functions. Proteins are made of 20 different subunits called amino acids that can be joined in a great variety of com ...
Nucleic acid
Nucleic acid

... Deoxyribonucleic acid (DNA) is a nucleic acid containing the genetic instructions used in the development and functioning of all known living organisms. The DNA segments carrying this genetic information are called genes Likewise, other DNA sequences have structural purposes, or are involved in regu ...
The MOLECULES of LIFE
The MOLECULES of LIFE

... DNA and RNA. Often these double helices are more stable than the natural DNA and RNA double helices with the same sequence of bases. Explain why such helices can form, and why they can be more stable. b. Given the increased stability of such modified nucleotides, why has nature not used them to bui ...
ch 10 UPDATED TRUNCATED BEST VERSION
ch 10 UPDATED TRUNCATED BEST VERSION

... proposed that DNA molecules consisted of 2 individual polymers of linked nucleotides in the shape of a double helix – In each strand the phosphate of one nucleotide bonds to the sugar of the next – The bases protrude from the sugar-phosphate ...
class02Sequencing-03.. - Department of Computer Science • NJIT
class02Sequencing-03.. - Department of Computer Science • NJIT

... independently of the chromosomes; artificial plasmids can be inserted into bacteria to amplify DNA for sequencing ...
12.1 Identifying the Substance of Genes
12.1 Identifying the Substance of Genes

Protein Synthesis
Protein Synthesis

... The 3' poly-A tail helps the mRNA against degradation by other molecules. • Lastly, the non-coding regions of the mRNA – known as the introns – are spliced out of the strand much like an editing room floor of a movie studio. This cutting and removing is carried out by spliceosomes. The remaining, us ...
Gum Drop Protein Synthesis
Gum Drop Protein Synthesis

... Your job is to create a model that shows the process of protein synthesis. You may use any materials you want to construct your models. Here are some ideas: colored paper, tape, toothpicks, candy, paper clips, erasers, clay, pipe cleaner, and beads. ...
Protein Synthesis Models
Protein Synthesis Models

... Your job is to create a model that shows the process of protein synthesis. You may use any materials you want to construct your models. Here are some ideas: colored paper, tape, toothpicks, candy, paper clips, erasers, clay, pipe cleaner, and beads. ...
The genetic material must show variation. Which of the following is
The genetic material must show variation. Which of the following is

... 7. The random collection of a sufficiently large sample of cloned fragments of the DNA of an organism to ensure that all of that organism's DNA is represented in the collection. (Two words.) 8. An enzyme used to add deoxyribonucleotides to the 3' ends of DNA chains without a template. (Two or three ...
Document
Document

... double helix. The bases are held together with weak hydrogen bonds that are broken apart by DNA helicase enzyme 2 . DNA Helicase uses energy of ATP to break apart the hydrogen bonds between the ...
BC2004
BC2004

... A common first step in analyzing a cloned DNA fragment or a PCR product is to construct its restriction map. By digesting the DNA with various restriction enzymes, alone and in combination, the number and relative positions of target sites along the DNA can be determined for each restriction enzyme. ...
Biology 445K Winter 2007 DNA Fingerprinting • For Friday 3/9 lab: in
Biology 445K Winter 2007 DNA Fingerprinting • For Friday 3/9 lab: in

... the genome that consist of repeated sequences. The repeat size is usually 10-60 base pairs long and the number of repeats varies from less than ten to several dozen. These sites, which are scattered throughout the genome, are usually “anonymous” markers in the sense that the repeat number does not a ...
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Replisome



The replisome is a complex molecular machine that carries out replication of DNA. The replisome first unwinds double stranded DNA into two single strands. For each of the resulting single strands, a new complementary sequence of DNA is synthesized. The net result is formation of two new double stranded DNA sequences that are exact copies of the original double stranded DNA sequence.In terms of structure, the replisome is composed of two replicative polymerase complexes, one of which synthesizes the leading strand, while the other synthesizes the lagging strand. The replisome is composed of a number of proteins including helicase, RFC, PCNA, gyrase/topoisomerase, SSB/RPA, primase, DNA polymerase I, RNAse H, and ligase.
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