Gluconeogenesis
... Regulation of pyruvate carboxylase Pyruvate carboxylase is allosterically activated by acyl-CoA. In order to activate bicarbonate, an acylCoA must be bound to an allosteric binding site of the enzyme. The second half of the enzyme catalyzed reaction, the nucleophilic attack of the pyruvate enolate ...
... Regulation of pyruvate carboxylase Pyruvate carboxylase is allosterically activated by acyl-CoA. In order to activate bicarbonate, an acylCoA must be bound to an allosteric binding site of the enzyme. The second half of the enzyme catalyzed reaction, the nucleophilic attack of the pyruvate enolate ...
Dynamics of Protein Tyrosine Nitration and
... reported that the peroxynitrite can inhibit the activity of MnSOD of Arabidopsis by nitration at Tyr63 residue [22]. In the nitrating conditions cytochrome c results in nitration at adaptable positions cytochrome c tyrosine. Whereas nitration of cytochrome C by peroxynitrite causes preferential modi ...
... reported that the peroxynitrite can inhibit the activity of MnSOD of Arabidopsis by nitration at Tyr63 residue [22]. In the nitrating conditions cytochrome c results in nitration at adaptable positions cytochrome c tyrosine. Whereas nitration of cytochrome C by peroxynitrite causes preferential modi ...
Optimizing cofactor availability for the production of recombinant
... production landscapes from microscale cultivations using 1 mM FeSO4-supplemented medium. Error bars are standard deviations from all measured clones of a landscape. Average activity from strains producing HRP alone was set to 100%. In addition to strong constitutive co-overexpression of either HEM1 ...
... production landscapes from microscale cultivations using 1 mM FeSO4-supplemented medium. Error bars are standard deviations from all measured clones of a landscape. Average activity from strains producing HRP alone was set to 100%. In addition to strong constitutive co-overexpression of either HEM1 ...
212_spring_2005_Platelets
... • Bind to subendothelial proteins and associated vWF subsequent to blood vessel injury • Activated via their interaction with collagen and ...
... • Bind to subendothelial proteins and associated vWF subsequent to blood vessel injury • Activated via their interaction with collagen and ...
Amino Acid Metabolism
... responsible for the vast majority of nitrogen metabolizing reactions in most organisms. • Protein degradation by the protozomal complex releases oligopeptides that are degraded into individual amino acids. • The urea cycle uses protons and electrons from ammonium ions and the amino acid aspartate to ...
... responsible for the vast majority of nitrogen metabolizing reactions in most organisms. • Protein degradation by the protozomal complex releases oligopeptides that are degraded into individual amino acids. • The urea cycle uses protons and electrons from ammonium ions and the amino acid aspartate to ...
novel nucleotide carrier proteins of Protochlamydia
... For example, members of the family Chlamydiaceae, comprising exclusively major obligate intracellular pathogens of humans like Chlamydia trachomatis, lost the ability to synthesize nucleotides de novo, and it has been shown that these essential building blocks are instead imported from the host cell ...
... For example, members of the family Chlamydiaceae, comprising exclusively major obligate intracellular pathogens of humans like Chlamydia trachomatis, lost the ability to synthesize nucleotides de novo, and it has been shown that these essential building blocks are instead imported from the host cell ...
Proteins in Serum and Urine - Ústav lékařské biochemie a
... In a weakly acidic environment albumin behaves as a cation. It can react with anionic dyes yielding an albumin-dye complex. Binding of the dye is associated with a change in color. The reaction takes place in weakly acidic medium in the presence of surface-active substances. Organic dyes are used th ...
... In a weakly acidic environment albumin behaves as a cation. It can react with anionic dyes yielding an albumin-dye complex. Binding of the dye is associated with a change in color. The reaction takes place in weakly acidic medium in the presence of surface-active substances. Organic dyes are used th ...
Lecture 03, NEW - terpenes + polyketides
... enzyme, passed from one active site to the next Different active sites carry out the ...
... enzyme, passed from one active site to the next Different active sites carry out the ...
Thyroid Hormones
... i. Binds to a receptor located in the nucleus or cytoplasm ii. Causes transformation of the receptor to an exposed DNA binding domain iii. Binds to an enhancer like element in DNA and causes the transcription of genes for a new protein leading to a physiologic response 1. the need for gene transcrip ...
... i. Binds to a receptor located in the nucleus or cytoplasm ii. Causes transformation of the receptor to an exposed DNA binding domain iii. Binds to an enhancer like element in DNA and causes the transcription of genes for a new protein leading to a physiologic response 1. the need for gene transcrip ...
Systembiologische Ansätze zur Erforschung des Metabolismus
... • Mass flow not linked with information flow. • However: Signal amplification requires that each activated enzyme must catalyse at least one further activation. • Minimum condition: Each activated enzyme catalyses exactly one further activation. • Thus, operational stoichiometric coupling of cascade ...
... • Mass flow not linked with information flow. • However: Signal amplification requires that each activated enzyme must catalyse at least one further activation. • Minimum condition: Each activated enzyme catalyses exactly one further activation. • Thus, operational stoichiometric coupling of cascade ...
User`s guide to GO
... Biological Process (BP or P) Molecular Function (MF or F) Cellular Component (CC or C) ...
... Biological Process (BP or P) Molecular Function (MF or F) Cellular Component (CC or C) ...
Relationship between Photosynthesis and Cellular Respiration
... higher lower concentration Only return to inner compartment through ATP synthases, “gates of the dam” As they move through, activate ATP synthase to make ATP from ADP + Pi This process is called Chemiosmosis (ATP production linked to H+ gradient) ...
... higher lower concentration Only return to inner compartment through ATP synthases, “gates of the dam” As they move through, activate ATP synthase to make ATP from ADP + Pi This process is called Chemiosmosis (ATP production linked to H+ gradient) ...
Probing the Role of a Conserved M1 Proline Residue in 5
... The 5-HT3A subunit forms a functional homomeric receptor when expressed in oocytes (Maricq et al., 1991) and was used for most of our experiments. However, while our studies were under way, cloning of the 5-HT3B subunit (Davies et al., 1999) suggested that the native 5-HT3 receptors are likely to be ...
... The 5-HT3A subunit forms a functional homomeric receptor when expressed in oocytes (Maricq et al., 1991) and was used for most of our experiments. However, while our studies were under way, cloning of the 5-HT3B subunit (Davies et al., 1999) suggested that the native 5-HT3 receptors are likely to be ...
MicroRNA Regulatory Patterns on the Human Metabolic Network
... regulate cellular metabolism: miRNAs could regulate transcription factors or signaling proteins, which in turn regulate metabolic enzymes. For example, Krutzfeldt and colleagues showed that miR-122 in mouse liver negatively regulate some transcriptional repressors which control plasma cholesterol co ...
... regulate cellular metabolism: miRNAs could regulate transcription factors or signaling proteins, which in turn regulate metabolic enzymes. For example, Krutzfeldt and colleagues showed that miR-122 in mouse liver negatively regulate some transcriptional repressors which control plasma cholesterol co ...
13-Krebs cycle
... Overview of Krebs cycle: The citric acid cycle – also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle– is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetyl-CoA derived from carbohydrates, fats and proteins into carbon dioxi ...
... Overview of Krebs cycle: The citric acid cycle – also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle– is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetyl-CoA derived from carbohydrates, fats and proteins into carbon dioxi ...
13-Krebs cycle
... Overview of Krebs cycle: The citric acid cycle – also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle– is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetyl-CoA derived from carbohydrates, fats and proteins into carbon dioxi ...
... Overview of Krebs cycle: The citric acid cycle – also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle– is a series of chemical reactions used by all aerobic organisms to generate energy through the oxidation of acetyl-CoA derived from carbohydrates, fats and proteins into carbon dioxi ...
Changes in gene expression associated with acclimation to constant
... have been generated as a result of this study. The most daily temperature fluctuations. Control of cell growth and notable of these hypotheses is the possibility that the high proliferation appears to be an important part of the mobility group b1 (HMGB1) protein, which plays key response to change i ...
... have been generated as a result of this study. The most daily temperature fluctuations. Control of cell growth and notable of these hypotheses is the possibility that the high proliferation appears to be an important part of the mobility group b1 (HMGB1) protein, which plays key response to change i ...
metabolism - Chavis Biology
... Sometimes genes are _________ only when an enzyme product is required to catalyze reactions that may occur infrequently. Other _________ are being transcribed all the time because their enzyme products are in constants demand. ...
... Sometimes genes are _________ only when an enzyme product is required to catalyze reactions that may occur infrequently. Other _________ are being transcribed all the time because their enzyme products are in constants demand. ...
Canine CD34: Cloning of the cDNA and Evaluation
... BMMC (2 X 107/mL) were stained with RpacaCD34 as described above, resuspended in PBSl28 horse serum, and sorted on a FACStar (Becton Dickinson). Lineage depletion of canine BMMC was performed with the following MoAbs: JD3 (anti-CD8):’ 1 E4 (antiCD4),3’ Tuk4 (antimonocyte; DAKO, Glostrup, Denmark), a ...
... BMMC (2 X 107/mL) were stained with RpacaCD34 as described above, resuspended in PBSl28 horse serum, and sorted on a FACStar (Becton Dickinson). Lineage depletion of canine BMMC was performed with the following MoAbs: JD3 (anti-CD8):’ 1 E4 (antiCD4),3’ Tuk4 (antimonocyte; DAKO, Glostrup, Denmark), a ...
pyruvate
... Concentrations of pyruvate, which maintain Pdh in the active form (Pdh-a) are sufficiently high so that, in energy-rich cells, the allosterically down-regulated, high Km form of Pdh is nonetheless capable of converting pyruvate to acetyl-CoA. With large amounts of pyruvate in cells having high energ ...
... Concentrations of pyruvate, which maintain Pdh in the active form (Pdh-a) are sufficiently high so that, in energy-rich cells, the allosterically down-regulated, high Km form of Pdh is nonetheless capable of converting pyruvate to acetyl-CoA. With large amounts of pyruvate in cells having high energ ...
Dynamics of the cellular metabolome during human cytomegalovirus infection.
... whereas consumption of FBP by aldolase is not, the most likely cause of the increase in FBP is increased PFK-1 flux. This conclusion is reinforced by the observation that levels of the aldolase product, dihydroxyacetone phosphate (DHAP), increase roughly in parallel with those of FBP (if the increase ...
... whereas consumption of FBP by aldolase is not, the most likely cause of the increase in FBP is increased PFK-1 flux. This conclusion is reinforced by the observation that levels of the aldolase product, dihydroxyacetone phosphate (DHAP), increase roughly in parallel with those of FBP (if the increase ...
ppt
... • substrates: lactate, pyruvate, glycerol, amino acids – Ala, Asp, Gln etc. • product: glucose • function: synthesis of Glc from non-sugar precursors • subcellular location: mitochondrial matrix + cytosol ...
... • substrates: lactate, pyruvate, glycerol, amino acids – Ala, Asp, Gln etc. • product: glucose • function: synthesis of Glc from non-sugar precursors • subcellular location: mitochondrial matrix + cytosol ...
Biochimie
... DAG:DAG transacylase (DGTA) utilize diacylglycerol (DAG), a central lipid intermediate, for direct incorporation into the TAG molecule. The candidate genes for PDAT are identifiable in some algal genomes; as for DGTA, no gene candidates have been identified in either higher plants or algae. The TAG as ...
... DAG:DAG transacylase (DGTA) utilize diacylglycerol (DAG), a central lipid intermediate, for direct incorporation into the TAG molecule. The candidate genes for PDAT are identifiable in some algal genomes; as for DGTA, no gene candidates have been identified in either higher plants or algae. The TAG as ...