schema-api-part1 - Bioinformatics Research Group at SRI
... Extracts data from a Pathway Tools PGDB Converts it to an XML schema Maps the data to Java objects and to a relational database Changes made to the data on the Java side can be committed back to a Pathway Tools PGDB ...
... Extracts data from a Pathway Tools PGDB Converts it to an XML schema Maps the data to Java objects and to a relational database Changes made to the data on the Java side can be committed back to a Pathway Tools PGDB ...
Drosophila - AOS-HCI-2011-Research
... species within the mitochondria and the increased free radical stress in cancer cells may cause further damage to both mtDNA and the electron transport chain, thus amplifying respiratory malfunctions and dependency on glycolysis. Hypoxia is another important factor that contributes to the Warburg ef ...
... species within the mitochondria and the increased free radical stress in cancer cells may cause further damage to both mtDNA and the electron transport chain, thus amplifying respiratory malfunctions and dependency on glycolysis. Hypoxia is another important factor that contributes to the Warburg ef ...
Key Residues Defining the ~.t-OpioidReceptor Binding Pocket: A
... examining receptor binding or a pharmacological response. Although these studies have been invaluable in producing highly potent and selective opioid agofists and antagonists, they provide only indirect information concerning receptor structure. With the cloning of the opioid receptors, the receptor ...
... examining receptor binding or a pharmacological response. Although these studies have been invaluable in producing highly potent and selective opioid agofists and antagonists, they provide only indirect information concerning receptor structure. With the cloning of the opioid receptors, the receptor ...
Semester 2
... Storage form of glucose made by joining glucose subunits into chains that is used by animal cells to store glucose for long-term energy A: What is glycogen ? S2C06 Jeopardy Review ...
... Storage form of glucose made by joining glucose subunits into chains that is used by animal cells to store glucose for long-term energy A: What is glycogen ? S2C06 Jeopardy Review ...
respiration jeopardy game!
... Storage form of glucose made by joining glucose subunits into chains that is used by animal cells to store glucose for long-term energy A: What is glycogen ? S2C06 Jeopardy Review ...
... Storage form of glucose made by joining glucose subunits into chains that is used by animal cells to store glucose for long-term energy A: What is glycogen ? S2C06 Jeopardy Review ...
Complement: a key system for immune surveillance and homeostasis
... Although complement is commonly depicted as a linear cascade of separate pathways, it is essentially a hub-like network that is tightly connected to other systems (Supplementary Fig. 1). Depending on the trigger, several initiation and regulatory mechanisms act together to produce an anticipated res ...
... Although complement is commonly depicted as a linear cascade of separate pathways, it is essentially a hub-like network that is tightly connected to other systems (Supplementary Fig. 1). Depending on the trigger, several initiation and regulatory mechanisms act together to produce an anticipated res ...
A consensus sequence in the endothelin
... opossum kidney cells; endothelin-A/endothelin-B chimeras; sodium/ hydrogen antiporter activity THE ENDOTHELINS (ET) are a family of three 21-amino acid peptides, ET-1, ET-2, and ET-3. They are involved in a variety of physiological responses, such as vascular smooth muscle cell contraction and dilat ...
... opossum kidney cells; endothelin-A/endothelin-B chimeras; sodium/ hydrogen antiporter activity THE ENDOTHELINS (ET) are a family of three 21-amino acid peptides, ET-1, ET-2, and ET-3. They are involved in a variety of physiological responses, such as vascular smooth muscle cell contraction and dilat ...
APC2 Antibody
... promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take ...
... promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take ...
Cloning and Effective Induction of Escherichia coli
... the expression of the desired gene placed under the control of the strong T7, lac or tac promoter. The advantage of using this synthetic inducer is that it cannot be hydrolyzed by β-galactosidase.13 However, the use of IPTG for the large-scale production of human therapeutic proteins is undesirable ...
... the expression of the desired gene placed under the control of the strong T7, lac or tac promoter. The advantage of using this synthetic inducer is that it cannot be hydrolyzed by β-galactosidase.13 However, the use of IPTG for the large-scale production of human therapeutic proteins is undesirable ...
Agonism with the omega-3 fatty acids α-linolenic acid
... a b s t r a c t The newly discovered G protein-coupled receptor GPR120 has recently been shown to stimulate secretion of the gut hormones glucagon-like peptide-1 and cholecystokinin upon binding of free fatty acids, thrusting it to the forefront of drug discovery efforts for treatment of type 2 diab ...
... a b s t r a c t The newly discovered G protein-coupled receptor GPR120 has recently been shown to stimulate secretion of the gut hormones glucagon-like peptide-1 and cholecystokinin upon binding of free fatty acids, thrusting it to the forefront of drug discovery efforts for treatment of type 2 diab ...
Biochemistry Lecture 16
... • Through CH3 of acetyl • Transient intermediate: citroyl CoA – Energy rel’d from cleavage acetylCoA • Why? What grps impt to exergonic rxn ...
... • Through CH3 of acetyl • Transient intermediate: citroyl CoA – Energy rel’d from cleavage acetylCoA • Why? What grps impt to exergonic rxn ...
Theoretical Approaches to the Evolutionary Optimization of Glycolysis
... the reaction. If many molecules of ATP are produced, it implies a good exploitation of the fuel, but very low global exergonism and a poor chemical affinity, and so a very poor ATP flux. (b) The distribution of local exergonisms along the pathway. The thermodynamic analysis developed in [14] led to ...
... the reaction. If many molecules of ATP are produced, it implies a good exploitation of the fuel, but very low global exergonism and a poor chemical affinity, and so a very poor ATP flux. (b) The distribution of local exergonisms along the pathway. The thermodynamic analysis developed in [14] led to ...
Ecological speciation model
... Enterics are a good example of reactions. They metabolize pyruvate to most of the products we discussed. ID of enterics critical to assess water quality. ...
... Enterics are a good example of reactions. They metabolize pyruvate to most of the products we discussed. ID of enterics critical to assess water quality. ...
Adenosine signaling mediates hypoxic responses in the chronic
... and T lymphocytes. Here, we show that the CLL lymph node niche is characterized by overexpression and activation of HIF-1a, which increases adenosine generation and signaling, affecting tumor and host cellular responses. Hypoxia in CLL lymphocytes modifies central metabolic pathways, protects against ...
... and T lymphocytes. Here, we show that the CLL lymph node niche is characterized by overexpression and activation of HIF-1a, which increases adenosine generation and signaling, affecting tumor and host cellular responses. Hypoxia in CLL lymphocytes modifies central metabolic pathways, protects against ...
Transcriptomic analysis reveals metabolic switches and
... conformation change, response to stress, cell cycle progress, chromatin assembly among others (Table 2 and Table S1). These results suggest the relevance of epigenetic regulation in T. cruzi life cycle. Also amino acid activation (synthesis of aminoacyl-tRNAs) and other proteins related to translati ...
... conformation change, response to stress, cell cycle progress, chromatin assembly among others (Table 2 and Table S1). These results suggest the relevance of epigenetic regulation in T. cruzi life cycle. Also amino acid activation (synthesis of aminoacyl-tRNAs) and other proteins related to translati ...
References - The University of New Mexico
... to adenosine triphosphate (ATP), adenosine diphosphate (ADP), inorganic phosphate (Pi), creatine phosphate (CrP), creatine (Cr) and lactate (La). However, the glycolytic pathway, reactions of glycogenolysis, and additional reactions of the phosphagen energy system (adenylate kinase and AMP deaminase ...
... to adenosine triphosphate (ATP), adenosine diphosphate (ADP), inorganic phosphate (Pi), creatine phosphate (CrP), creatine (Cr) and lactate (La). However, the glycolytic pathway, reactions of glycogenolysis, and additional reactions of the phosphagen energy system (adenylate kinase and AMP deaminase ...
Full version (PDF file)
... only 0.001 % of total glucose concentration, α-oxoaldehydes are characterized by extremely high chemical activity. They are up to 20,000-fold as reactive as glucose, thus being able to form AGE-structures even at very low concentrations. Physiologically, α-oxoaldehydes react directly with protein te ...
... only 0.001 % of total glucose concentration, α-oxoaldehydes are characterized by extremely high chemical activity. They are up to 20,000-fold as reactive as glucose, thus being able to form AGE-structures even at very low concentrations. Physiologically, α-oxoaldehydes react directly with protein te ...
lec 7 Metabolism of purine nucleotides
... 2-defect in purine metabolism: increased synthesis of purine nucleotides which may be idiopathic (with unknown cause) or due to increased levels of PRPP that stimulate synthetic pathway of purine nucleotides. The increased purine lead to increased uric acid production Secondary causes: such as diet ...
... 2-defect in purine metabolism: increased synthesis of purine nucleotides which may be idiopathic (with unknown cause) or due to increased levels of PRPP that stimulate synthetic pathway of purine nucleotides. The increased purine lead to increased uric acid production Secondary causes: such as diet ...
Glycolysis and Gluconeogenesis
... oxidation and cleavage of glucose ATP generation (with and without oxygen) all cells in the cytosol (the reducing equivalents are transferred to the electron-transport chain by the shuttle) ...
... oxidation and cleavage of glucose ATP generation (with and without oxygen) all cells in the cytosol (the reducing equivalents are transferred to the electron-transport chain by the shuttle) ...
BIOINFORMATICS ORIGINAL PAPER Going from where to why—interpretable prediction of protein subcellular localization
... very complex making it difficult to understand why a particular prediction was made. Moreover, most predictors do not provide a confidence estimate. Consequently, predictions cannot be verified with regard to their significance and reliability. In this work, we present YLoc, a novel method for predi ...
... very complex making it difficult to understand why a particular prediction was made. Moreover, most predictors do not provide a confidence estimate. Consequently, predictions cannot be verified with regard to their significance and reliability. In this work, we present YLoc, a novel method for predi ...
Slide 1
... Prevents ubiquitination-mediated degradation Readily translocated across nucleus Retains transcriptional ability ...
... Prevents ubiquitination-mediated degradation Readily translocated across nucleus Retains transcriptional ability ...
... Most enzymes are pH dependent for their activity. Usually they have a pH-optimum which is suited to the environment in which they are generally found. Reasons for this may be that the amino acids in the active site need to be in a certain state of ionization to be active, that the substrate has to ...