Gas-Chromatography Mass-Spectrometry (GC
... distinctive gene and metabolic networks. In addition there is accumulating evidence of horizontal gene transfer among marine organisms especially from bacteria to algae [2,3] by means of which algae could involve new enzymes into their metabolic networks. Such an evolutional background renders algae ...
... distinctive gene and metabolic networks. In addition there is accumulating evidence of horizontal gene transfer among marine organisms especially from bacteria to algae [2,3] by means of which algae could involve new enzymes into their metabolic networks. Such an evolutional background renders algae ...
Impaired ATP Synthase Assembly Associated with
... a syndrome termed NARP. There was good correlation between mutant load and disease severity (3). This was further documented when it was shown that very high levels of T8993G mutant mtDNA were associated with a severe neurodegenerative disease of childhood (maternally inherited Leigh syndrome, or MI ...
... a syndrome termed NARP. There was good correlation between mutant load and disease severity (3). This was further documented when it was shown that very high levels of T8993G mutant mtDNA were associated with a severe neurodegenerative disease of childhood (maternally inherited Leigh syndrome, or MI ...
Folic Acid and Its Receptors - OPUS
... by most bacteria, including E. coli, to create folate (28). These bacteria synthesize PABA from chorismate using PABA synthase (29), which is also the precursor to aromatic amino acids (30). There are a few bacteria strains that cannot synthesize folate on their own and must take it in from an exter ...
... by most bacteria, including E. coli, to create folate (28). These bacteria synthesize PABA from chorismate using PABA synthase (29), which is also the precursor to aromatic amino acids (30). There are a few bacteria strains that cannot synthesize folate on their own and must take it in from an exter ...
Gary K - Monell Chemical Senses Center
... determined by olfaction, this decrease in the ability to smell can affect food preferences and even nutritional status of older adults. The “spiciness” of food is conveyed through a third sensory system known as chemical irritation. Chemical irritation is a warning system that tells us when the body ...
... determined by olfaction, this decrease in the ability to smell can affect food preferences and even nutritional status of older adults. The “spiciness” of food is conveyed through a third sensory system known as chemical irritation. Chemical irritation is a warning system that tells us when the body ...
PowerPoint lecture
... are known (such as Friedreich’s ataxia); many of those afflicted die young ...
... are known (such as Friedreich’s ataxia); many of those afflicted die young ...
Poster
... to cure people who contract multidrug resistant tuberculosis. This strategy has the potential to enhance or replace existing antibiotics targeting M. tuberculosis. By inhibiting either the active site in the catalytic domain or activating the allosteric site in the C-terminal domain, scientists woul ...
... to cure people who contract multidrug resistant tuberculosis. This strategy has the potential to enhance or replace existing antibiotics targeting M. tuberculosis. By inhibiting either the active site in the catalytic domain or activating the allosteric site in the C-terminal domain, scientists woul ...
Iron-sulfur proteins and the role of iron in the gene expression of
... 2. FeS clusters and FeS proteins Proteins that contain iron-sulfur (FeS) clusters as a prosthetic group are widely utilised in all living organisms for a variety of cellular processes. Inorganic FeS metal compounds were already present in hydrothermal vents in the anaerobic atmosphere of the ancien ...
... 2. FeS clusters and FeS proteins Proteins that contain iron-sulfur (FeS) clusters as a prosthetic group are widely utilised in all living organisms for a variety of cellular processes. Inorganic FeS metal compounds were already present in hydrothermal vents in the anaerobic atmosphere of the ancien ...
Sequence-Specific Deoxyribonucleic Acid (DNA) Recognition by
... (Fig. 1). Another noteworthy feature of SF1 regulation is that many genes appear to be regulated in collaboration with proximally bound, structurally diverse transcription factors including cAMP response element binding protein (CREB), CCAAT-enhancer binding protein (C/EBP-!), pituitary homeobox (Pi ...
... (Fig. 1). Another noteworthy feature of SF1 regulation is that many genes appear to be regulated in collaboration with proximally bound, structurally diverse transcription factors including cAMP response element binding protein (CREB), CCAAT-enhancer binding protein (C/EBP-!), pituitary homeobox (Pi ...
Innovative Purification Protocol for Heparin Binding
... between several related structures while they perform their biological function, these functional rearrangements, these tertiary and quaternary structures are referred to as conformations and transition between them are called conformational changes [7, 14, 28]. The structure of proteins can be divi ...
... between several related structures while they perform their biological function, these functional rearrangements, these tertiary and quaternary structures are referred to as conformations and transition between them are called conformational changes [7, 14, 28]. The structure of proteins can be divi ...
brv12140 - Cambridge Repository
... II. Biochemistry and evolutionary origin of the pentose phosphate pathway . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (1) The L-type PPP and alternative or extended reaction sequences of the PPP . . . . . . . . . . . . . . . . . . . . . . (2) The subcellular localization of the PPP and ...
... II. Biochemistry and evolutionary origin of the pentose phosphate pathway . . . . . . . . . . . . . . . . . . . . . . . . . . . . . (1) The L-type PPP and alternative or extended reaction sequences of the PPP . . . . . . . . . . . . . . . . . . . . . . (2) The subcellular localization of the PPP and ...
Journal of Biotechnology Evaluation of 13C isotopic tracers for
... et al., 2007). Metabolic analysis of cancer cells has again become an active area of research, and technological improvements have expanded our ability to investigate metabolism using stable isotopically labeled substrates. In this study we used the A549 cancer cell line as a model system for evalua ...
... et al., 2007). Metabolic analysis of cancer cells has again become an active area of research, and technological improvements have expanded our ability to investigate metabolism using stable isotopically labeled substrates. In this study we used the A549 cancer cell line as a model system for evalua ...
GLUCONEOGENESIS
... 1. The production of ATP, generated by the degradation of glucose. 2. The provision of building blocks for synthetic reactions, such as the formation of fatty acids. ...
... 1. The production of ATP, generated by the degradation of glucose. 2. The provision of building blocks for synthetic reactions, such as the formation of fatty acids. ...
Drug-Resistant Variants of Escherichia coli Thymidylate Synthase
... Kinetic Characterization of ecTS and Pro-254 Variants— Steady-State Determinations. The concentration of purified enzymes was determined using a molar extinction coefficient at 280 nm of 1.13 ⫻ 105 M⫺1 cm⫺1, and the number of binding sites was determined by FdUMP titration of protein absorbance at 3 ...
... Kinetic Characterization of ecTS and Pro-254 Variants— Steady-State Determinations. The concentration of purified enzymes was determined using a molar extinction coefficient at 280 nm of 1.13 ⫻ 105 M⫺1 cm⫺1, and the number of binding sites was determined by FdUMP titration of protein absorbance at 3 ...
NIH Public Access
... (NuPage), which were developed at 150 V (constant) for ∼1 h or until the tracking dye reached the bottom of the slab. For Western analysis of T229 phosphorylation in His6-S6K1αII(ΔAID)T389E (0.2 μg), proteins were transferred from the gel to Nitrocellulose Membrane Filter Paper Sandwich (Invitrogen) ...
... (NuPage), which were developed at 150 V (constant) for ∼1 h or until the tracking dye reached the bottom of the slab. For Western analysis of T229 phosphorylation in His6-S6K1αII(ΔAID)T389E (0.2 μg), proteins were transferred from the gel to Nitrocellulose Membrane Filter Paper Sandwich (Invitrogen) ...
Gluconeogenesis
... Digestive breakdown is unregulated - 100%! But tissue glycogen is an important energy reservoir - its breakdown is carefully controlled Glycogen consists of "granules" of high MW range from 6 x 106 ~ 1600 x 106 Glycogen phosphorylase cleaves glucose from the nonreducing ends of glycogen molecules Th ...
... Digestive breakdown is unregulated - 100%! But tissue glycogen is an important energy reservoir - its breakdown is carefully controlled Glycogen consists of "granules" of high MW range from 6 x 106 ~ 1600 x 106 Glycogen phosphorylase cleaves glucose from the nonreducing ends of glycogen molecules Th ...
A. Work Accomplished by You and/or Others Cellular biology of
... A. Work Accomplished by You and/or Others Cellular biology of protein chaperones Protein molecular chaperones play critical roles in cellular biology. The family of proteins classified as molecular chaperones is large and diverse, but is united by a common characteristic – the ability to form transi ...
... A. Work Accomplished by You and/or Others Cellular biology of protein chaperones Protein molecular chaperones play critical roles in cellular biology. The family of proteins classified as molecular chaperones is large and diverse, but is united by a common characteristic – the ability to form transi ...
Lecture 15 (Parker) - Department of Chemistry ::: CALTECH
... Some aspects of this enzyme’s control are like those of the pyruvate dehydrogenase complex, as might be expected by the homology of the reactions catalyzed by these two enzymes. ...
... Some aspects of this enzyme’s control are like those of the pyruvate dehydrogenase complex, as might be expected by the homology of the reactions catalyzed by these two enzymes. ...
Enzymes of Glycolysis Are Functionally Associated
... of 7 of the 10 enzymes that constitute the glycolytic pathway. Four of these enzymes (glyceraldehyde-3-P dehydrogenase, aldolase, phosphoglycerate mutase, and enolase) were also identified in an intermembrane space/outer mitochondrial membrane fraction. Enzyme activity assays confirmed that the enti ...
... of 7 of the 10 enzymes that constitute the glycolytic pathway. Four of these enzymes (glyceraldehyde-3-P dehydrogenase, aldolase, phosphoglycerate mutase, and enolase) were also identified in an intermembrane space/outer mitochondrial membrane fraction. Enzyme activity assays confirmed that the enti ...
Chapter 7 – Cellular Respiration
... Phases of aerobic cellular respiration 1. Glycolysis 2. Transition or Acetyl-CoA reaction 3. Krebs cycle 4. Electron transport system These phases are nothing more than metabolic reactions involving the conversion of glucose & other molecules into carbon dioxide & water The resulting energy released ...
... Phases of aerobic cellular respiration 1. Glycolysis 2. Transition or Acetyl-CoA reaction 3. Krebs cycle 4. Electron transport system These phases are nothing more than metabolic reactions involving the conversion of glucose & other molecules into carbon dioxide & water The resulting energy released ...
1 Cholesterol synthesis, uptake, and regulation I. Structure and
... compound lanosterol, from which the 27-carbon compound cholesterol is derived. ...
... compound lanosterol, from which the 27-carbon compound cholesterol is derived. ...
FC Chimeric Fusion Protein Purified Human
... Fas (APO-1, CD95) is a 45 kDa cell surface protein that mediates apoptosis when cross-linked with agonistic anti-Fas antibodies or Fas ligand (FasL). Fas belongs to the TNF (tumor necrosis factor)/NGF (nerve growth factor) receptor family, and is expressed in various tissues and cells including the ...
... Fas (APO-1, CD95) is a 45 kDa cell surface protein that mediates apoptosis when cross-linked with agonistic anti-Fas antibodies or Fas ligand (FasL). Fas belongs to the TNF (tumor necrosis factor)/NGF (nerve growth factor) receptor family, and is expressed in various tissues and cells including the ...
At the Intersection of the Pathways for Exocytosis and
... proteins, Rho3 and Cdc42 (He et al., 2007; He & Guo, 2009), or by TC10 in mammalian cells (Dupraz et al., 2009; Inoue et al., 2006; Pommereit & Wouters, 2007). Recognition of the exocytic vesicle by the exocyst is mediated by the Rab GTPase proteins, Sec4 in yeast (Guo et al., 1999; Zajac et al., 20 ...
... proteins, Rho3 and Cdc42 (He et al., 2007; He & Guo, 2009), or by TC10 in mammalian cells (Dupraz et al., 2009; Inoue et al., 2006; Pommereit & Wouters, 2007). Recognition of the exocytic vesicle by the exocyst is mediated by the Rab GTPase proteins, Sec4 in yeast (Guo et al., 1999; Zajac et al., 20 ...