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The Proteins of the Keratin Component of Bird`s Beaks
The Proteins of the Keratin Component of Bird`s Beaks

... these proteins show an overall similarity in composition. This is particularly evident in their contents of glycine (about 30 residues %), tyrosine, serine and proline which together account for 55-60 % of the total residues. Their content of half-cystine, determined as S-carboxymethyl cysteine, is ...
Direct and Long-Range Action of a DPP Morphogen
Direct and Long-Range Action of a DPP Morphogen

... Constitutive Activation of the DPP Receptors Punt and TKV Causes Cell-Autonomous Expression of spalt and omb The ability of spatially indiscriminate DPP expression to induce ectopic omb and spalt expression suggests that during normal development the anteroposterior extent of omb and spalt expressio ...
Synthetic biology for engineering acetyl coenzyme a
Synthetic biology for engineering acetyl coenzyme a

... serves as initial electron acceptors in the catalytic process; and FAD, which is bound to E3 and serves as an internal elector acceptor in the regeneration of oxidized lipoic acid. In the last step of the catalytic cycle, the electrons are transferred from FADH2 to NAD⫹. The PDH complex has a comple ...
Reaction of glycolysis
Reaction of glycolysis

... Glyceraldehyde-3-Phohsphate is Converted to Pyruvate (Cont’d) •1,3-bisphosphoglycerate is converted to 3 phosphoglycerate •This step (step 7) involves another reaction in which ATP is produced by phosphorylation of ADP •1,3-bisphosphoglycerate transfers a phosphate group to ADP. This is known as su ...
darkreactions
darkreactions

... A few days ago we said (in lecture) that the transketolase reaction was Kn + Am  Kn-2 + Am+2 That’s wrong: we do donate two carbons from the ketose to the aldose, but they swap carbonyl positions when you do, so the reaction is really Kn + Am  An-2 + Km+2 The notes have already been corrected! ...
Introduction - MRC Laboratory of Molecular Biology
Introduction - MRC Laboratory of Molecular Biology

... Circadian rhythms are cell-autonomous phenomena found throughout biology and have been shown to regulate many aspects of health and disease1. Despite this almost ubiquitous observation of cellular timekeeping, the genes generally proposed to be responsible show little or no homology between kingdoms ...
Modelling glycolysis with Cellware
Modelling glycolysis with Cellware

1 22,25 October 2004 Physiology of Locomotion R. B. Huey I. Some
1 22,25 October 2004 Physiology of Locomotion R. B. Huey I. Some

... [3. Arginine phosphate (not PCr) is the phosphagen for most invertebrates] 4. No oxygen involved, so these are "anaerobic" pathways ...
Session 1B - Rubisco and Photorespiration
Session 1B - Rubisco and Photorespiration

TCA Cycle - eCurriculum
TCA Cycle - eCurriculum

... Malate dehydrogenase (step 8):  Too much NADH inhibits the regeneration of oxaloacetate. ...
Respiration and Lipid Metabolism - Roberto Cezar | Fisiologista
Respiration and Lipid Metabolism - Roberto Cezar | Fisiologista

Growing Membranes, Sustaining Cells
Growing Membranes, Sustaining Cells

... cells. (A) The synthesis of glucose (gluconeogenesis) in liver cells depends on three metabolic compartments: the cytoplasm, mitochondrial matrix, and endoplasmic reticulum (ER) lumen. Three key kinases in glycolysis—hexokinase, phosphofructokinase, and pyruvate kinase—catalyze nonreversible reactio ...
Cell-Free Phospholipid Biosynthesis by Gene
Cell-Free Phospholipid Biosynthesis by Gene

... Life as we know it is compartmentalized: a continuous membrane encloses the cytoplasm protecting it from the environment and specifying a unit of evolutionary selection. This cellular envelop is primarily made of phospholipids that, together with specific proteins, control shape transformation and r ...
Enzymes II: Regulation
Enzymes II: Regulation

... isoenzymes (or isozymes), and those which are genetically determined may be called primary isoenzymes. The different primary isoenzymes catalyze the same chemical reaction but may differ in their primary structure and kinetic properties. The tissue distribution of isoenzymes imparts distinctive prop ...
Divalent Metal Ions in Plant Mitochondria and Their Role in
Divalent Metal Ions in Plant Mitochondria and Their Role in

... and cell organelle functions. The redox-inactive heavy metal cadmium exhibits strong affinity for oxygen, nitrogen, and sulfur atoms (Nieboer and Richardson, 1980) and can inhibit enzyme activity by direct blocking of protein function or displacement of natural metal centers. There are numerous repo ...
Unnatural Amino Acid Mutagenesis of the GABAA Receptor Binding
Unnatural Amino Acid Mutagenesis of the GABAA Receptor Binding

... The binding pockets of Cys-loop receptors are dominated by aromatic amino acids. In the GABAA receptor ␣1Phe65, ␤2Tyr97, ␤2Tyr157, and ␤2Tyr205 are present at the ␤2 /␣1 interface and have been implicated in forming an important part of the GABA binding site. Here, we have probed interactions of the ...
UDP-sugar pyrophosphorylase controls the activity of proceeding
UDP-sugar pyrophosphorylase controls the activity of proceeding

... dissect this observation we analyzed the activity of glucuronokinase12 as a representative enzyme of the sugar-1-kinase group and of USP in transgenic lines showing a downregulation of USP by expression of a miRNA targeted against the USP gene. Figure 2 shows the activity of USP in correlation with ...
A Histone H3.3-like Gene Specifically Expressed in the Vegetative
A Histone H3.3-like Gene Specifically Expressed in the Vegetative

Cloning, Purification, and Partial Characterization of the
Cloning, Purification, and Partial Characterization of the

Evolution of Plant-Like Crystalline Storage Polysaccharide in the
Evolution of Plant-Like Crystalline Storage Polysaccharide in the

... storage polysaccharide accumulated in the cytoplasm by Toxoplasma gondii and that of the dinoflagellate Crypthecodinium cohnii can be defined as a genuine starch. We show that it is synthesized through a UDP-glucose-based pathway much simpler than that described for plants. This pathway is very simila ...
mitochondria
mitochondria

... small intermembrane space in between. The outer membrane has many protein-based pores that are big enough to allow the passage of ions and molecules as large as a small protein. In contrast, the inner membrane has much more restricted permeability, much like the plasma membrane of a cell. The inner ...
Authors` version - The Computable Plant
Authors` version - The Computable Plant

... for L-valine and L-isoleucine biosynthesis are catalyzed by a set of bi-functional enzymes that bind substrates from either pathway, L-valine inhibition of the first enzyme specific for its biosynthesis catalyzed by a single α-acetohydroxy acid synthase (AHAS) could compromise the cell for L-isoleuc ...
Histoplasma capsulatum an effective mechanism for trans-cell wall transfer
Histoplasma capsulatum an effective mechanism for trans-cell wall transfer

... including the H and M antigens, pluripotent glycoproteins that elicit both humoral and T cell-mediated immune responses (Zancope-Oliveira et al., 1999; Fisher and Woods, 2000; Deepe and Gibbons, 2001a), and a virulence-related, phase-specific protein (YPS3p), which is found at the cell wall (Bohse a ...
Report Organelles in Blastocystis that Blur the
Report Organelles in Blastocystis that Blur the

... of the multienzyme PDH complex (Figure 3 and Table S2). Thus, Blastocystis has two ways to decarboxylate pyruvate to form acetyl-CoA: one involves the classic mitochondrial PDH complex and the other involves the anaerobic PFO (Figure 3). Interestingly, although no PFO has been found yet in Nyctother ...
Study of the distribution of autotrophic CO2 fixation
Study of the distribution of autotrophic CO2 fixation

... 3-hydroxypropionate/4-hydroxybutyrate cycle using acetyl-coenzyme A (CoA)/propionyl-CoA carboxylase as the carboxylating enzyme has been identified for (micro)aerobic members of the Sulfolobales. The dicarboxylate/4-hydroxybutyrate cycle using oxygen-sensitive pyruvate synthase and phosphoenolpyruva ...
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Biochemical cascade

A biochemical cascade (or a signaling pathway) is a series of chemical reactions which are initiated by a stimulus (first messenger) acting on a receptor that is transduced to the cell interior through second messengers (which amplify the initial signal) and ultimately to effector molecules, resulting in a cell response to the initial stimulus. At each step of the signaling cascade, various controlling factors are involved to regulate cellular actions, responding effectively to cues about their changing internal and external environments.
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