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Understanding the acetylome: translating targeted
Understanding the acetylome: translating targeted

... (AceK), which are involved in the distribution of isocitrate into the TCA cycle and glyoxylate pathways when citrate is in abundance. Immunoprecipitation followed by pan-acetyllysine immunoblotting demonstrated that GapA, AceA, and AceK are hyperacetylated in the ⌬CobB strain, concomitant with incre ...
Progesterone-stimulated intracellular calcium increase in human
Progesterone-stimulated intracellular calcium increase in human

... Dipartimento di Fisiopatologia Clinica, Unità di Andrologia, Università di Firenze, viale Pieraccini 6, I-50139 Firenze, Italy 1To ...
Chemical Inactivation of the Cinnamate 4
Chemical Inactivation of the Cinnamate 4

... anionic site opposite (i.e. at about 8.5 Å) to the position of oxidative attack (Schalk et al., 1997, 1998). The most efficient inhibitors of the C4H share the same structural characteristics as the substrates. Depending on the functions present in the molecule, they behave as simple competitors or ...
Sixth Southeast Enzyme Conference
Sixth Southeast Enzyme Conference

Aromatic amino acid metabolism
Aromatic amino acid metabolism

... Tyrosine and phenylalanine synthesis  A mutase converts chorismate into prephenate, the immediate precursor of the aromatic ring of tyrosine and phenylalanine.  Prephenate is oxidatively decarboxylated to phydroxyphenylpyruvate.  Alternatively, dehydration followed by decarboxylation yields phen ...
BIOCHEMISTRY AND MOLECULAR BIOLOGY Problem Unit Five
BIOCHEMISTRY AND MOLECULAR BIOLOGY Problem Unit Five

... surface receptors. Signal binding triggers transmembrane signaling and a signal transduction pathway. Arachidonic acid is released from membrane phospholipids and converted to thromboxane A2 signal path continues ultimately stimulating platelet granular content release. Originally disc shaped, bound ...
Electrone transport chain and oxidative phosphorylation
Electrone transport chain and oxidative phosphorylation

... The other major sugar found in fruits and vegetables is sucrose, a disaccharide of glucose and fructose. Sucrose and small amounts of the monosaccharides glucose and fructose are the major natural sweeteners found in fruit, honey, and vegetables. Dietary fiber, that portion of the diet that cannot b ...
Novel Multiprotein Complexes Identified in the Hyperthermophilic
Novel Multiprotein Complexes Identified in the Hyperthermophilic

... are assemblies composed of multiple proteins (2). Many biological processes involve multiprotein complexes that function as large and efficient machines, such as ribosomes (3, 4), flagella (5), and cellulosomes (6). In addition, the supramolecular organization of enzymes of partial or entire metabol ...
The proton-linked monocarboxylate transporter (MCT) family
The proton-linked monocarboxylate transporter (MCT) family

Orexin Autoimmunity
Orexin Autoimmunity

... Hypothesized that narcolepsy caused by autoimmune destruction of orexin neurons and receptors Has not been proven despite vast amounts of research since the 80’s Some correlations that maintain idea of autoimmune involvement Specific orexin cell loss in CSF of postmortem analysis of narcolepsy patie ...
Karbohidrat Metabolizması
Karbohidrat Metabolizması

... - its breakdown is carefully controlled • Glycogen consists of "granules" of high MW • Glycogen phosphorylase cleaves glucose from the nonreducing ends of glycogen molecules • This is a phosphorolysis, not a hydrolysis • Metabolic advantage: product is a sugar-P - a "sort-of" glycolysis substrate ...
A non-canonical pathway for aromatic amino acid biosynthesis in
A non-canonical pathway for aromatic amino acid biosynthesis in

... Combination of Bacitracin, protease and the PEG method ............... 139 ...
Fermentation metabolism and its evolution in algae
Fermentation metabolism and its evolution in algae

Karbohidrat Metabolizması
Karbohidrat Metabolizması

... - its breakdown is carefully controlled • Glycogen consists of "granules" of high MW • Glycogen phosphorylase cleaves glucose from the nonreducing ends of glycogen molecules • This is a phosphorolysis, not a hydrolysis • Metabolic advantage: product is a sugar-P - a "sort-of" glycolysis substrate ...
Bioreaction Network Topology and Metabolic Flux Ratio
Bioreaction Network Topology and Metabolic Flux Ratio

An iso-15:0 O-alkylglycerol moiety is the key structure of the E
An iso-15:0 O-alkylglycerol moiety is the key structure of the E

... (Lorenzen et al., 2014). Figure 4 illustrates fruiting body formation in M. xanthus wild ...
PhoR, PhoP and MshC: Three essential proteins of Mycobacterium
PhoR, PhoP and MshC: Three essential proteins of Mycobacterium

... of PhoRin and PhoP, a pull-down method was developed using the non-hydrolyzable ATP analog, adenosine 5′-(β,γ-imido)triphosphate (AMP-PNP). A stable PhoRin-AMPPNP-PhoP complex was not identified. Future work is necessary for the crystallization of PhoRex and PhoRin. A new DNA binding assay is also n ...
Focus Issue on Plastid Biology Update Novel
Focus Issue on Plastid Biology Update Novel

... activase are controlled by thioredoxin. Trx f donates electrons to target proteins that have a broad range of redox midpoint potentials Em (Hutchinson et al. 2000). Differential inactivation of target proteins e.g. in the Calvin cycle, is unrelated to the value of Em but highly relevant for photoin ...
檔案下載
檔案下載

... Fructose 1,6-bisphosphate is generated from glucose 6-phosphate • The isomerization of glucose 6-phophate to fructose 6-phosphate – Conversion of an aldose into ketose – Catalyzed by phosphoglucose isomerase ...
Elsevier Scientific Publishing Company, Amsterdam
Elsevier Scientific Publishing Company, Amsterdam

... low effectiveness of dimyristoylphosphatidylcholine was not improved after increasing the proton conductance or ionic fluxes through the bilayer by addition of uncoupler or uncoupler plus valinomycin in the presence of potassium chloride. In Fig. 3 it is shown that activation by long-chain phosphati ...
10 Translocation in the Phloem Chapter
10 Translocation in the Phloem Chapter

... metabolic functions, such as protein synthesis, that are reduced or lost during differentiation of the sieve elements (Bostwick et al. 1992). In addition, the numerous mitochondria in companion cells may supply energy as ATP to the sieve elements. There are at least three different types of companio ...
NMDA Receptor Function and Physiological Modulation
NMDA Receptor Function and Physiological Modulation

... cyclic adenosine monophosphate response element binding protein (CREB), a transcription factor, resulting in activation of gene expression. One of the genes upregulated in response to activated CREB is brainderived neurotrophic factor (BDNF), which acts to promote prosurvival programs. In contrast, ...


... Mycobacterial factors that allow inhibit phagolysosomal destruction and bacterial surviving into host macrophages remains elusive, therefore the studies of proteins and pathways involved in these specific evasion mechanisms during mycobacterial infections represent a challenge for understanding of M ...
Multiomics of tomato glandular trichomes reveals
Multiomics of tomato glandular trichomes reveals

... chromatograms of LA1777 (Supplemental Figure 2). These results confirm previous metabolite analyses of tomato trichomes and underline that trichomes of these species produce different terpenoid secondary metabolites (Slocombe et al., 2008; Besser et al., 2009; Schilmiller et al., 2010; McDowell e ...
Small decrease of plastid transketolase activity in
Small decrease of plastid transketolase activity in

... OPPP activity was not strongly inhibited by decreased TK activity. These results identify TK activity as an important determinant of photosynthetic and phenylpropanoid metabolism and show that the provision of precursors by primary metabolism colimits flux into the shikimate pathway and phenylpropan ...
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Biochemical cascade

A biochemical cascade (or a signaling pathway) is a series of chemical reactions which are initiated by a stimulus (first messenger) acting on a receptor that is transduced to the cell interior through second messengers (which amplify the initial signal) and ultimately to effector molecules, resulting in a cell response to the initial stimulus. At each step of the signaling cascade, various controlling factors are involved to regulate cellular actions, responding effectively to cues about their changing internal and external environments.
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