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... Therefore, we will delineate fructose-induced tissue and organ dysfunctions resulting from these direct and/or indirect dangerous factors. It will focus on the correlations between different metabolites and functional assignment of different tissues and organs in the whole body under high fructose c ...
... Therefore, we will delineate fructose-induced tissue and organ dysfunctions resulting from these direct and/or indirect dangerous factors. It will focus on the correlations between different metabolites and functional assignment of different tissues and organs in the whole body under high fructose c ...
and Rhizobiales-Like PPP-Family Protein Phosphatases from
... okadaic acid and microcystin-LR, as well as diversity in their phosphorylated substrate specificities. Bioinformatics complemented cell biology also uncovered unique subcellular localizations for each enzyme, with AtSLP1, 2 and AtRLPH2 being chloroplastic, mitochondrial and nuclear / cytosolic, resp ...
... okadaic acid and microcystin-LR, as well as diversity in their phosphorylated substrate specificities. Bioinformatics complemented cell biology also uncovered unique subcellular localizations for each enzyme, with AtSLP1, 2 and AtRLPH2 being chloroplastic, mitochondrial and nuclear / cytosolic, resp ...
Development 128, 4439-4447 (2001)
... head region (marked by krox20 and otx2) similar to that caused by Xolloid (Fig. 1A-C). In addition, co-injection of Tsg and Xolloid did not cause further reduction in head structures (Fig. 1D). As Xolloid cleaves Chordin (Piccolo et al., 1997), it seemed possible that the ventralizing activity of Ts ...
... head region (marked by krox20 and otx2) similar to that caused by Xolloid (Fig. 1A-C). In addition, co-injection of Tsg and Xolloid did not cause further reduction in head structures (Fig. 1D). As Xolloid cleaves Chordin (Piccolo et al., 1997), it seemed possible that the ventralizing activity of Ts ...
Expanded roles of leucine-responsive regulatory protein in
... et al., 2002). A certain proportion of the regulated genes are involved, as originally proposed, in transport and metabolism of amino acids, but Lrp has also been suggested to regulate genes involved in biosynthesis and degradation of various metabolites other than amino acids (Brinkman et al., 2003 ...
... et al., 2002). A certain proportion of the regulated genes are involved, as originally proposed, in transport and metabolism of amino acids, but Lrp has also been suggested to regulate genes involved in biosynthesis and degradation of various metabolites other than amino acids (Brinkman et al., 2003 ...
Inducible uptake and metabolism of glucose by the phosphorylative
... grown on glucose showed O2 uptake with glucose but failed to respire on gluconate and 2-ketogluconate. Naphthaleneand succinate-grown cells showed poor O2 uptake when incubated with glucose. Strains CSV89 and KT2442 showed O2 uptake in the presence of glucose, gluconate and 2ketogluconate (Table 1). ...
... grown on glucose showed O2 uptake with glucose but failed to respire on gluconate and 2-ketogluconate. Naphthaleneand succinate-grown cells showed poor O2 uptake when incubated with glucose. Strains CSV89 and KT2442 showed O2 uptake in the presence of glucose, gluconate and 2ketogluconate (Table 1). ...
Supplementary materials - Stanford Artificial Intelligence Laboratory
... learned the tree by adding a decision node to a context. The first added node becomes the root that creates two contexts, and we search for the candidate regulators that can make the decision node for those two contexts. When considering adding a decision node to the regulatory program of each modul ...
... learned the tree by adding a decision node to a context. The first added node becomes the root that creates two contexts, and we search for the candidate regulators that can make the decision node for those two contexts. When considering adding a decision node to the regulatory program of each modul ...
Cra-mediated regulation of Escherichia coli adenylate cyclase
... of many genes (Saier & Ramseier, 1996). cAMP is also essential for transcriptional regulation of many genes via its receptor protein CRP. When complexed with CAMP, CRP binds to specific sites upstream of promoters, causing transcriptional activation or repression (Kolb et al., 1993). A CRP binding s ...
... of many genes (Saier & Ramseier, 1996). cAMP is also essential for transcriptional regulation of many genes via its receptor protein CRP. When complexed with CAMP, CRP binds to specific sites upstream of promoters, causing transcriptional activation or repression (Kolb et al., 1993). A CRP binding s ...
Development of prokaryotic cell-free systems for synthetic
... Selection of model organism is critical as different E. coli strains offer a variety of different advantages over one another. Strains are differentiated by their engineered traits, some of which are very conducive to the controlled expression of protein. Choice of organism presents the first unit o ...
... Selection of model organism is critical as different E. coli strains offer a variety of different advantages over one another. Strains are differentiated by their engineered traits, some of which are very conducive to the controlled expression of protein. Choice of organism presents the first unit o ...
ATP regulation in bioproduction
... S. cerevisiae requires one molecule of ATP per molecule of ammonia to take up and assimilate the latter as a nitrogen source. In contrast, only 0.5 molecule of ATP is required for the uptake of one molecule of urea. Milne et al. [26] introduced a non-ATP consuming urease from Schizosaccharomyces pom ...
... S. cerevisiae requires one molecule of ATP per molecule of ammonia to take up and assimilate the latter as a nitrogen source. In contrast, only 0.5 molecule of ATP is required for the uptake of one molecule of urea. Milne et al. [26] introduced a non-ATP consuming urease from Schizosaccharomyces pom ...
Metabolic decision making by protein-metabolite - ETH E
... Metabolism lies at the core of microbial life and fuels all cellular activities with building blocks, reducing power, and energy. To regulate metabolic activity, microbes utilize a complex network of regulatory layers, such as transcriptional regulation, covalent posttranslational modificat ...
... Metabolism lies at the core of microbial life and fuels all cellular activities with building blocks, reducing power, and energy. To regulate metabolic activity, microbes utilize a complex network of regulatory layers, such as transcriptional regulation, covalent posttranslational modificat ...
ATP regulation in bioproduction
... S. cerevisiae requires one molecule of ATP per molecule of ammonia to take up and assimilate the latter as a nitrogen source. In contrast, only 0.5 molecule of ATP is required for the uptake of one molecule of urea. Milne et al. [26] introduced a non-ATP consuming urease from Schizosaccharomyces pom ...
... S. cerevisiae requires one molecule of ATP per molecule of ammonia to take up and assimilate the latter as a nitrogen source. In contrast, only 0.5 molecule of ATP is required for the uptake of one molecule of urea. Milne et al. [26] introduced a non-ATP consuming urease from Schizosaccharomyces pom ...
FREE Sample Here
... full file at http://testbankcorner.eu 42) Which of the following would increase the likelihood of an action potential being generated in a postsynaptic cell? A) presynaptic inhibition at an excitatory synapse B) presynaptic excitation at an excitatory synapse C) opening of potassium channels on the ...
... full file at http://testbankcorner.eu 42) Which of the following would increase the likelihood of an action potential being generated in a postsynaptic cell? A) presynaptic inhibition at an excitatory synapse B) presynaptic excitation at an excitatory synapse C) opening of potassium channels on the ...
Plasmodium falciparum: multifaceted resistance to artemisinins
... active preparation to efficiently resume proliferation [38]. The development cycle of P. falciparum presents normal arrest at the sporozoite stage in the mosquito salivary glands or at the gametocyte stage in red blood cells. In vitro, P. falciparum cell cycle progression can be strongly delayed at ...
... active preparation to efficiently resume proliferation [38]. The development cycle of P. falciparum presents normal arrest at the sporozoite stage in the mosquito salivary glands or at the gametocyte stage in red blood cells. In vitro, P. falciparum cell cycle progression can be strongly delayed at ...
AMP-activated protein kinase and metabolic control - HAL
... 2. Rational for a pharmacological management of T2D by targeting AMPK Physical activity is an important determinant to prevent and control T2D. Current guidelines recommend practical, regular and moderate regimens of physical activity. The multiple metabolic adaptations that occur in response to phy ...
... 2. Rational for a pharmacological management of T2D by targeting AMPK Physical activity is an important determinant to prevent and control T2D. Current guidelines recommend practical, regular and moderate regimens of physical activity. The multiple metabolic adaptations that occur in response to phy ...
CENTRAL TEXAS COLLEGE
... Recognize that cells are the basic structure of all living things and occur as different cell types which have specialized parts that perform specific functions. G. Describe the form and function of cellular membranes and relate the importance of the structure of the plasma membrane to the transport ...
... Recognize that cells are the basic structure of all living things and occur as different cell types which have specialized parts that perform specific functions. G. Describe the form and function of cellular membranes and relate the importance of the structure of the plasma membrane to the transport ...
Amino Acids
... specific aa’s combined into regular 2º structural elements. • In contrast to globular proteins, whose shapes result from complex interactions b/w 2º, 3º, and sometimes 4º elements. ...
... specific aa’s combined into regular 2º structural elements. • In contrast to globular proteins, whose shapes result from complex interactions b/w 2º, 3º, and sometimes 4º elements. ...
A conserved N-‐terminal domain of Rif2 regulates telomere length in
... DNA binding complexes, there are other proteins that associate with telomeres and help regulate both end-‐protection and telomere length. These include a number of proteins that are involved in DNA break ...
... DNA binding complexes, there are other proteins that associate with telomeres and help regulate both end-‐protection and telomere length. These include a number of proteins that are involved in DNA break ...
Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) and Cyclic
... decompensated, shifting to the more irreversible state of heart failure [9,10]. It is therefore important to determine which Ca2+ signaling processes control the development of cardiac hypertrophy. Persistent activation of the β-adrenergic and renin-angiotensin-aldosterone systems (RAS) is a hallmar ...
... decompensated, shifting to the more irreversible state of heart failure [9,10]. It is therefore important to determine which Ca2+ signaling processes control the development of cardiac hypertrophy. Persistent activation of the β-adrenergic and renin-angiotensin-aldosterone systems (RAS) is a hallmar ...
sample - Test Bank Exam
... Page Ref: 199 16) The extent of neurotransmitter binding to receptors on the postsynaptic membrane is determined primarily by which of the following? A) sodium B) calcium C) the distance of the cleft D) the concentration of neurotransmitter E) neurotransmitter vesicles Answer: D Diff: 4 Page Ref: 19 ...
... Page Ref: 199 16) The extent of neurotransmitter binding to receptors on the postsynaptic membrane is determined primarily by which of the following? A) sodium B) calcium C) the distance of the cleft D) the concentration of neurotransmitter E) neurotransmitter vesicles Answer: D Diff: 4 Page Ref: 19 ...
PDF hosted at the Radboud Repository of the Radboud University
... itochondria are motile organelles that not only produce energy in the form of ATP, but also participate in a number of intracellular processes such as the generation, modulation, and propagation of cytosolic Ca2þ signals and the control of life and death through apoptosis. In addition, they are a co ...
... itochondria are motile organelles that not only produce energy in the form of ATP, but also participate in a number of intracellular processes such as the generation, modulation, and propagation of cytosolic Ca2þ signals and the control of life and death through apoptosis. In addition, they are a co ...
H2S-NSAIDs
... mesenteric artery, portal vein, and other vascular tissue.(23, 29) In some tissues, CSE and CBS are both required for H2S synthesis, whereas in others only one of these enzymes is necessary.(1) CSE appears to be the predominant enzymatic source of H2S in the vasculature and heart,(1) while in the ce ...
... mesenteric artery, portal vein, and other vascular tissue.(23, 29) In some tissues, CSE and CBS are both required for H2S synthesis, whereas in others only one of these enzymes is necessary.(1) CSE appears to be the predominant enzymatic source of H2S in the vasculature and heart,(1) while in the ce ...
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... molecular mechanisms underlying aberrant pulmonary artery remodeling to identify pathways for intervention. While there is a well-recognized heritable genetic component to PAH, there is also evidence of other genetic perturbations, including pulmonary vascular cell DNA damage, activation of the DNA ...
... molecular mechanisms underlying aberrant pulmonary artery remodeling to identify pathways for intervention. While there is a well-recognized heritable genetic component to PAH, there is also evidence of other genetic perturbations, including pulmonary vascular cell DNA damage, activation of the DNA ...
Functional characterization of the Mycobacterium
... Eukaryotic-like Ser/Thr protein kinases (STPKs) are present in many bacterial species, where they control various physiological and virulence processes by enabling microbial adaptation to specific environmental signals. PknJ is the only member of the 11 STPKs identified in Mycobacterium tuberculosis ...
... Eukaryotic-like Ser/Thr protein kinases (STPKs) are present in many bacterial species, where they control various physiological and virulence processes by enabling microbial adaptation to specific environmental signals. PknJ is the only member of the 11 STPKs identified in Mycobacterium tuberculosis ...
EP 1790660 B1
... [0020] The method will typically involve the steps of: obtaining nucleic acid encoding a protein of the invention; manipulating said nucleic acid to remove at least one domain from within the protein. The resulting nucleic acid may be inserted into an expression vector, or may already be part of an ...
... [0020] The method will typically involve the steps of: obtaining nucleic acid encoding a protein of the invention; manipulating said nucleic acid to remove at least one domain from within the protein. The resulting nucleic acid may be inserted into an expression vector, or may already be part of an ...
Paracrine signalling
Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.