
Mechanical stimuli of skeletal muscle: implications on mTOR/p70s6k
... Accepted: 25 September 2007 © Springer-Verlag 2007 ...
... Accepted: 25 September 2007 © Springer-Verlag 2007 ...
Chapter 9 Proteins - Angelo State University
... 5. Regulatory function: Body processes regulated by proteins include growth (growth hormone) and thyroid functions (thyrotropin). 6. Nerve impulse transmission: Some proteins act as receptors for small molecules that transmit impulses across the synapses that separate nerve cells (e.g., rhodopsin in ...
... 5. Regulatory function: Body processes regulated by proteins include growth (growth hormone) and thyroid functions (thyrotropin). 6. Nerve impulse transmission: Some proteins act as receptors for small molecules that transmit impulses across the synapses that separate nerve cells (e.g., rhodopsin in ...
Session 377 Visual cycle and phototransduction
... Purpose: Rapid inactivation of the visual pigment by phosphorylation is essential for the timely termination of rod and cone photoresponses and the recovery of photoreceptor sensitivity following a bleach. However, the role of pigment dephosphorylation in dark adaptation of rods and cones and the id ...
... Purpose: Rapid inactivation of the visual pigment by phosphorylation is essential for the timely termination of rod and cone photoresponses and the recovery of photoreceptor sensitivity following a bleach. However, the role of pigment dephosphorylation in dark adaptation of rods and cones and the id ...
Dynamics of Protein Metabolism in the Ruminant
... glycoproteins of mucus). Energy substrates come from the residual fermentable fibre, the glycocalyx of rumen microorganisms, starch and other polysaccharides that have resisted rumen and enteric digestion. As the amount of fermentable energy from the diet reaching the lower tract increases, microbia ...
... glycoproteins of mucus). Energy substrates come from the residual fermentable fibre, the glycocalyx of rumen microorganisms, starch and other polysaccharides that have resisted rumen and enteric digestion. As the amount of fermentable energy from the diet reaching the lower tract increases, microbia ...
Overview of Metabolism - Chapter 4 - Formatted
... of dynamic equilibrium, constantly taking in substances from its external environment, processing them, synthesizing its own requirements, degrading what is old or harmful, and sending out what it may have produced for other cells, or what is waste. Since all these processes either require energy or ...
... of dynamic equilibrium, constantly taking in substances from its external environment, processing them, synthesizing its own requirements, degrading what is old or harmful, and sending out what it may have produced for other cells, or what is waste. Since all these processes either require energy or ...
Role of Water Mediated Interactions in Protein
... protein association may appear as a deceivingly simple process. One might think that two proteins, complementary with each other in shape and electrostatics, approach as rigid bodies and dock into the native protein complex. This is the celebrated “lock-and-key” paradigm of protein association, hypo ...
... protein association may appear as a deceivingly simple process. One might think that two proteins, complementary with each other in shape and electrostatics, approach as rigid bodies and dock into the native protein complex. This is the celebrated “lock-and-key” paradigm of protein association, hypo ...
The Effects of Whey Supplementation and Natural Diet on Protein
... Protein and Exercise Protein Needs for Athletes Nutrition plays an important role in the promotion of training adaptations. According to The Institute of Medicine, 10-35% of daily calories for an average adult should come from protein, so active adults should be between 25-35%. The amount of protei ...
... Protein and Exercise Protein Needs for Athletes Nutrition plays an important role in the promotion of training adaptations. According to The Institute of Medicine, 10-35% of daily calories for an average adult should come from protein, so active adults should be between 25-35%. The amount of protei ...
Selective and specific cleavage of the D 1 and D2 proteins of
... fragment of the D2 protein were each equivalent to about 2% of those of the intact proteins in the control sample. This result contrasts with the observation under photoinhibitory illumination that the DI protein is more susceptible to cleavage than the D2 protein [6,8,27]. Fig. 3A shows the effects ...
... fragment of the D2 protein were each equivalent to about 2% of those of the intact proteins in the control sample. This result contrasts with the observation under photoinhibitory illumination that the DI protein is more susceptible to cleavage than the D2 protein [6,8,27]. Fig. 3A shows the effects ...
31P n.m.r. analysis of the renal response to respiratory acidosis
... 2.2s, unidentified peak at 11.1 p.p.m. (including AMP) 1 . 9 ~ 1 gave absolute values for adenine nucleotides and phosphate which differ significantly from those obtained by enzymic assay in the same kidney. The differences cannot be explained as artifacts from breakdown of the normal renal constitu ...
... 2.2s, unidentified peak at 11.1 p.p.m. (including AMP) 1 . 9 ~ 1 gave absolute values for adenine nucleotides and phosphate which differ significantly from those obtained by enzymic assay in the same kidney. The differences cannot be explained as artifacts from breakdown of the normal renal constitu ...
How to obtain labeled proteins and what to do with... Marlon J Hinner and Kai Johnsson
... studies on a protein involved in Hedgehog signaling, which were carried out using SNAP-tag [40] and ACP labeling [41], respectively. Self-labeling proteins have recently been demonstrated to work in living animals. This allows the introduction of fluorophores that absorb and emit light in the far-re ...
... studies on a protein involved in Hedgehog signaling, which were carried out using SNAP-tag [40] and ACP labeling [41], respectively. Self-labeling proteins have recently been demonstrated to work in living animals. This allows the introduction of fluorophores that absorb and emit light in the far-re ...
Membrane Protein Expression in Cell
... proteins. The rapidly growing number of successfully produced targets in combination with the continuous development of new applications significantly promotes the distribution of this technology. Membrane protein synthesis by cell-free expression does not appear to be restricted by origin, size or ...
... proteins. The rapidly growing number of successfully produced targets in combination with the continuous development of new applications significantly promotes the distribution of this technology. Membrane protein synthesis by cell-free expression does not appear to be restricted by origin, size or ...
Protein Annotation & Advanced Insilico Based Mutation Hotspot Oryza sativa *
... RASMOL. The major step of the research is to evaluate the effect of the substitution mutation at the hot spot site on the stability, functionality disease occurrence and tolerability of the protein. These parameters were calculated using various insilico tools. The final summary of the work is that ...
... RASMOL. The major step of the research is to evaluate the effect of the substitution mutation at the hot spot site on the stability, functionality disease occurrence and tolerability of the protein. These parameters were calculated using various insilico tools. The final summary of the work is that ...
Full-Text PDF
... (mRNA) that will allow for differential gene expression patterns to emerge during the process of transcription. The mRNAs are subsequently processed by an array of splicing and editing mechanisms before exiting the nucleus to the cytoplasm. Within the cytoplasm, the mRNAs will interact with large ri ...
... (mRNA) that will allow for differential gene expression patterns to emerge during the process of transcription. The mRNAs are subsequently processed by an array of splicing and editing mechanisms before exiting the nucleus to the cytoplasm. Within the cytoplasm, the mRNAs will interact with large ri ...
Fig. 1 - Development - The Company of Biologists
... Pluripotent stem cells possess a very specific metabolic profile that likely reflects their rapid proliferation and the specific microenvironment from which they are derived. As the epiblast transitions from the pre-implantation to the post-implantation stage, its external environment changes dramat ...
... Pluripotent stem cells possess a very specific metabolic profile that likely reflects their rapid proliferation and the specific microenvironment from which they are derived. As the epiblast transitions from the pre-implantation to the post-implantation stage, its external environment changes dramat ...
Partial characterization of human complement factor H by protein
... for C3 turnover is regulated in a number of ways, and the principal route is via proteolytic destruction ofC3b. C3b is destroyed by the complement protease factor I. This reaction requires a protein cofactor, which forms a complex with C3b. Only C3b in the C3b-cofactor complex is cleaved by factor I ...
... for C3 turnover is regulated in a number of ways, and the principal route is via proteolytic destruction ofC3b. C3b is destroyed by the complement protease factor I. This reaction requires a protein cofactor, which forms a complex with C3b. Only C3b in the C3b-cofactor complex is cleaved by factor I ...
Conformational flexibility may explain multiple cellular roles of PEST
... be overrepresented in the proteins belonging to nucleic acid and protein binding, transcription regulation, and signal transduction classes.15 They were also found to be surface exposed, enriched in characterized disordered protein database, and contribute largely to eukaryotic protein disorder.15 T ...
... be overrepresented in the proteins belonging to nucleic acid and protein binding, transcription regulation, and signal transduction classes.15 They were also found to be surface exposed, enriched in characterized disordered protein database, and contribute largely to eukaryotic protein disorder.15 T ...
Metazoan Remaining Genes for Essential Amino Acid Biosynthesis
... of BHMT in metazoans have shown that it uses betaine and L-homocysteine as substrates, generating L-methionine and dimethylglycine [39]. However, in fungi and plants, it uses S-methyl-L-methionine and L-homocystheine as substrates producing 2 L-methionine; or uses S-adenosyl-L-methionine and L-homoc ...
... of BHMT in metazoans have shown that it uses betaine and L-homocysteine as substrates, generating L-methionine and dimethylglycine [39]. However, in fungi and plants, it uses S-methyl-L-methionine and L-homocystheine as substrates producing 2 L-methionine; or uses S-adenosyl-L-methionine and L-homoc ...
TFE3 contains two activation domains, one acidic and the other
... we wondered if part of the activation properties of TFE3L were dependent upon synergistic stimulation of transcription by the separate N-terminal and C-terminal activation domains. ^ ^ We first addressed this question in the context of the nativeTFE3 protein. Transcriptional activation was compared ...
... we wondered if part of the activation properties of TFE3L were dependent upon synergistic stimulation of transcription by the separate N-terminal and C-terminal activation domains. ^ ^ We first addressed this question in the context of the nativeTFE3 protein. Transcriptional activation was compared ...
Membrane Transport - Bioenergetics and Cell Metabolism
... Sphingomyelin and phophatidyl choline are located on the outer leaflet Phosphatdidylserine is located in the inner leaflet ...
... Sphingomyelin and phophatidyl choline are located on the outer leaflet Phosphatdidylserine is located in the inner leaflet ...
NO 2
... Determination of host specificity The binding of flavonoids to the NodD gene product is one of the major determinants of rhizobial host specificity because each plant species produces its own specific set of flavonoid molecules and each rhizobial species recognizes only a limited number of flavo ...
... Determination of host specificity The binding of flavonoids to the NodD gene product is one of the major determinants of rhizobial host specificity because each plant species produces its own specific set of flavonoid molecules and each rhizobial species recognizes only a limited number of flavo ...
Hepatocyte Growth Factor Induces Wnt
... been shown to be important in embryogenesis and carcinogenesis. The aim of this study was to elucidate the mechanism of functional similarities observed in the two pathways. We used normal rat liver, primary hepatocyte cultures and a dominant-negative Met expression system to study the effect of HGF ...
... been shown to be important in embryogenesis and carcinogenesis. The aim of this study was to elucidate the mechanism of functional similarities observed in the two pathways. We used normal rat liver, primary hepatocyte cultures and a dominant-negative Met expression system to study the effect of HGF ...
Open access - Bioinformation
... diseasewith varying clinical outcomes, disease progression, and responses to specific treatmentsattributed by a wide array of elements ranging from tumorintrinsic genetic factorstoextrinsic ...
... diseasewith varying clinical outcomes, disease progression, and responses to specific treatmentsattributed by a wide array of elements ranging from tumorintrinsic genetic factorstoextrinsic ...
Cell wall-deficient, L-form bacteria in the 21st century: a personal
... bacterial variants that are capable of living in a cell wall-free state, called the L-form (or L-phase). There was an extensive literature on L-forms, going back to the 1930s [13,14], largely based on hospital case histories of patients with infections refractory to treatment with β-lactam antibioti ...
... bacterial variants that are capable of living in a cell wall-free state, called the L-form (or L-phase). There was an extensive literature on L-forms, going back to the 1930s [13,14], largely based on hospital case histories of patients with infections refractory to treatment with β-lactam antibioti ...
SFE1, a Constituent of the Fertilization Envelope
... oocyte following germinal vesicle breakdown. Our findings suggest that the gene encoding this major product of the egg is activated concomitantly with the other cortical granule-specific products already identified, and that a common LDLr-like motif of the fertilization envelope may reveal a structu ...
... oocyte following germinal vesicle breakdown. Our findings suggest that the gene encoding this major product of the egg is activated concomitantly with the other cortical granule-specific products already identified, and that a common LDLr-like motif of the fertilization envelope may reveal a structu ...
HICA by the Labrada Research Team HICA
... kidney failure patients. This improved lean mass retention and nitrogen balance for this group of people. Normally, this is not an issue for most, but during catabolic breakdown, the loss of leucine can be more quickly replaced. HICA can also be oxidized to create KIC, possibly providing some the of ...
... kidney failure patients. This improved lean mass retention and nitrogen balance for this group of people. Normally, this is not an issue for most, but during catabolic breakdown, the loss of leucine can be more quickly replaced. HICA can also be oxidized to create KIC, possibly providing some the of ...
Paracrine signalling

Paracrine signaling is a form of cell-cell communication in which a cell produces a signal to induce changes in nearby cells, altering the behavior or differentiation of those cells. Signaling molecules known as paracrine factors diffuse over a relatively short distance (local action), as opposed to endocrine factors (hormones which travel considerably longer distances via the circulatory system), juxtacrine interactions, and autocrine signaling. Cells that produce paracrine factors secrete them into the immediate extracellular environment. Factors then travel to nearby cells in which the gradient of factor received determines the outcome. However, the exact distance that paracrine factors can travel is not certain.Although paracrine signaling elicits a diverse array of responses in the induced cells, most paracrine factors utilize a relatively streamlined set of receptors and pathways. In fact, different organs in the body -even between different species - are known to utilize a similar sets of paracrine factors in differential development. The highly conserved receptors and pathways can be organized into four major families based on similar structures: Fibroblast growth factor (FGF) family, Hedgehog family, Wnt family, and TGF-β superfamily. Binding of a paracrine factor to its respective receptor initiates signal transduction cascades, eliciting different responses.