Leukaemia Section t(9;22)(q34;q11) in ANLL Atlas of Genetics and Cytogenetics
... impaired adherence to bone marrow stroma cells, ...
... impaired adherence to bone marrow stroma cells, ...
Python Libraries for Computational Chemistry and Biology
... Only one sequence was found, cloned, and sequenced. It’s now called “VR1” (“vanilloid receptor 1”) (Sounds so simple, doesn’t it?) ...
... Only one sequence was found, cloned, and sequenced. It’s now called “VR1” (“vanilloid receptor 1”) (Sounds so simple, doesn’t it?) ...
Factor VIlI-Related Protein Circulates in Normal
... Taken together with recent agarose gel filtration studies,’7 our data, and similar results obtained independently is very ...
... Taken together with recent agarose gel filtration studies,’7 our data, and similar results obtained independently is very ...
Ubiquitin-Mediated Control of Plant Hormone
... emerging data demonstrates that regulated protein degradation rivals the well-studied area of transcriptional regulation for importance in cellular regulation. In this Update, we will highlight current research findings that illustrate the contributions of the UPS to phytohormone signaling. We will a ...
... emerging data demonstrates that regulated protein degradation rivals the well-studied area of transcriptional regulation for importance in cellular regulation. In this Update, we will highlight current research findings that illustrate the contributions of the UPS to phytohormone signaling. We will a ...
Evolution of Gamete Recognition Proteins
... rapid evolution of fertilization proteins by positive selection are known, and concerted evolution can influence the differentiation of gamete recognition proteins between closely related species. Sexual reproduction, defined here as the fusion of two haploid cells during fertilization to form a dip ...
... rapid evolution of fertilization proteins by positive selection are known, and concerted evolution can influence the differentiation of gamete recognition proteins between closely related species. Sexual reproduction, defined here as the fusion of two haploid cells during fertilization to form a dip ...
Database searching
... Aligned DNA sequences can be represented by a 4 ·n profile matrix reflecting the frequencies of nucleotides in every aligned position. ...
... Aligned DNA sequences can be represented by a 4 ·n profile matrix reflecting the frequencies of nucleotides in every aligned position. ...
Hydrogen exchange mass spectrometry for the analysis of protein
... with more classical functional data, a more thorough understanding of protein function can be obtained. In many cases, protein dynamics are directly related to specific protein functions such as conformational changes during enzyme activation or protein movements during binding. The method is made p ...
... with more classical functional data, a more thorough understanding of protein function can be obtained. In many cases, protein dynamics are directly related to specific protein functions such as conformational changes during enzyme activation or protein movements during binding. The method is made p ...
8. ARTÍCULOS
... F-box motif, both generally recognized as hallmarks of such enzymes), we checked whether M2-PK might be a ubiquitination substrate of HERC1. Nevertheless, since ubiquitination of M2-PK has not been described, we ¢rst set about determining whether M2-PK undergoes ubiquitination under physiological co ...
... F-box motif, both generally recognized as hallmarks of such enzymes), we checked whether M2-PK might be a ubiquitination substrate of HERC1. Nevertheless, since ubiquitination of M2-PK has not been described, we ¢rst set about determining whether M2-PK undergoes ubiquitination under physiological co ...
Selenocysteine: The 21 Amino Acid
... by the genes sel A and sel D. The gene sel D requires the presence of selenium which it converts to selenophosphate at the cost of one ATP molecule. Selenophosphate contains a high energy bond and is thus considered “activated.” The product of sel A converts the charged serine residue to a more acti ...
... by the genes sel A and sel D. The gene sel D requires the presence of selenium which it converts to selenophosphate at the cost of one ATP molecule. Selenophosphate contains a high energy bond and is thus considered “activated.” The product of sel A converts the charged serine residue to a more acti ...
Proteomic Analysis of the Arabidopsis Nucleolus Suggests Novel
... function is unknown, but time-lapse microscopy has shown the cavity apparently emptying its contents into the nucleoplasm (Gunning, URL: www.plantcellbiologyonCD. com) and Beven et al. (1995, 1996) showed accumulation of snoRNAs and the presence of spliceosomal snRNAs in the nucleolar cavity. Althou ...
... function is unknown, but time-lapse microscopy has shown the cavity apparently emptying its contents into the nucleoplasm (Gunning, URL: www.plantcellbiologyonCD. com) and Beven et al. (1995, 1996) showed accumulation of snoRNAs and the presence of spliceosomal snRNAs in the nucleolar cavity. Althou ...
X-ray structure of the C-terminal domain of a coronavirus nucle
... colds and other severe illnesses such as SARS (severe acute respiratory syndrome). The coronaviruses are enveloped viruses with a diameter ranging from 80 to 160 nm . The viral genome consists of a single 30 kb long segment of positive sense single-stranded RNA (Siddell 1995). Upon infection the gen ...
... colds and other severe illnesses such as SARS (severe acute respiratory syndrome). The coronaviruses are enveloped viruses with a diameter ranging from 80 to 160 nm . The viral genome consists of a single 30 kb long segment of positive sense single-stranded RNA (Siddell 1995). Upon infection the gen ...
Amino Acids
... What are they and how your body uses them? Proteins, vitamins, minerals, carbohydrates and fats are the essential nutrients that make up your body. They are responsible for growth and daily function. When water and fats are eliminated, proteins make up 75% of the body solids that are left. They a ...
... What are they and how your body uses them? Proteins, vitamins, minerals, carbohydrates and fats are the essential nutrients that make up your body. They are responsible for growth and daily function. When water and fats are eliminated, proteins make up 75% of the body solids that are left. They a ...
as a PDF
... splice was expressed predominantly in testis. The C2 splice had a more general expression pattern. Therefore, in addition to the distinct features revealed by amino acid sequences, these splice variants also were expressed in a tissue-specific manner. Because the N0 splice contained sequences shared ...
... splice was expressed predominantly in testis. The C2 splice had a more general expression pattern. Therefore, in addition to the distinct features revealed by amino acid sequences, these splice variants also were expressed in a tissue-specific manner. Because the N0 splice contained sequences shared ...
Nucleotide sequences of genome segments $8, encoding a capsid
... amino-terminal amino acids and 18 of the last 25 carboxy-terminal amino acids are identical in the three viruses. Some regions with stretches of 10 amino acids identical were detected between residues 381 and 390 of RGDV and 377 to 386 of RDV, and between residues 414 to 423 of RGDV and 415 to 424 o ...
... amino-terminal amino acids and 18 of the last 25 carboxy-terminal amino acids are identical in the three viruses. Some regions with stretches of 10 amino acids identical were detected between residues 381 and 390 of RGDV and 377 to 386 of RDV, and between residues 414 to 423 of RGDV and 415 to 424 o ...
Nucleotide sequences of genome segments $8, encoding a capsid
... amino-terminal amino acids and 18 of the last 25 carboxy-terminal amino acids are identical in the three viruses. Some regions with stretches of 10 amino acids identical were detected between residues 381 and 390 of RGDV and 377 to 386 of RDV, and between residues 414 to 423 of RGDV and 415 to 424 o ...
... amino-terminal amino acids and 18 of the last 25 carboxy-terminal amino acids are identical in the three viruses. Some regions with stretches of 10 amino acids identical were detected between residues 381 and 390 of RGDV and 377 to 386 of RDV, and between residues 414 to 423 of RGDV and 415 to 424 o ...
Chemistry in living systems
... Rideout and coworkers recognized the potential use of ketones and aldehydes for chemoselective drug assembly in the presence of living cells53, 54, 55. They reported that decanal and octyl aminoguanidine—both independently harmless to cells—react selectively to form a hydrazone-linked detergent cap ...
... Rideout and coworkers recognized the potential use of ketones and aldehydes for chemoselective drug assembly in the presence of living cells53, 54, 55. They reported that decanal and octyl aminoguanidine—both independently harmless to cells—react selectively to form a hydrazone-linked detergent cap ...
Efficiency assay of detergent removal columns on - G
... respectively. Every second, a TOF MS precursor ion spectrum was accumulated, followed by three product ion spectra, each for 3 s. LC‐MS/MS: Nano‐LC was performed with an nano 2D LC (Eksigent) equipped with a Dionex C18 PepMap100 column (75 µm i.d.) flowing at 200 nL/min. Peptides (5 µL injections) w ...
... respectively. Every second, a TOF MS precursor ion spectrum was accumulated, followed by three product ion spectra, each for 3 s. LC‐MS/MS: Nano‐LC was performed with an nano 2D LC (Eksigent) equipped with a Dionex C18 PepMap100 column (75 µm i.d.) flowing at 200 nL/min. Peptides (5 µL injections) w ...
Chapter 3 - HCC Learning Web
... can cause serious physical and mental problems, may be prescribed to treat diseases such as cancer and AIDS, and – are abused by athletes to enhance performance. ...
... can cause serious physical and mental problems, may be prescribed to treat diseases such as cancer and AIDS, and – are abused by athletes to enhance performance. ...
Resonance-assignement-Structure-constraints
... The receiver coil picks up the signal from the sample. An analog-to-digital converter “reads” the voltage and sends it to the computer for data storage. ...
... The receiver coil picks up the signal from the sample. An analog-to-digital converter “reads” the voltage and sends it to the computer for data storage. ...
Reprogramming Cells to Fight Disease
... While this was effective for some diseases, most notably insulin for treating diabetes and monoclonal antibodies for cancer treatments, only 20 protein replacement drugs have been developed in the last 40 years. This leaves over 6,000 rare diseases left untreated. As researchers learned more about g ...
... While this was effective for some diseases, most notably insulin for treating diabetes and monoclonal antibodies for cancer treatments, only 20 protein replacement drugs have been developed in the last 40 years. This leaves over 6,000 rare diseases left untreated. As researchers learned more about g ...
Deciphering the genetic code Dr. Syndey Brenner estabilished mRNA
... GTP is hydrolyzed and 50S subunit is recruited with loss of IF’s. Note – in prokaryotes three initiation factors are known (IF-1, IF-2, IF-3) whereas eukaryotes have over 10 initiation factors (eIF) The large ribosomal subunit then joins the complex, and a functional ribosome is formed with th ...
... GTP is hydrolyzed and 50S subunit is recruited with loss of IF’s. Note – in prokaryotes three initiation factors are known (IF-1, IF-2, IF-3) whereas eukaryotes have over 10 initiation factors (eIF) The large ribosomal subunit then joins the complex, and a functional ribosome is formed with th ...
Diversity of the Superfamily of Phloem Lectins (Phloem Protein 2) in
... (Schulz, 1990) and seedless vascular plants. Cucurbits have been used as a model plant for many phloem studies because of their distinctive phloem anatomy and prolific vascular exudation. In Cucurbita spp., two predominant P-proteins, the phloem filament protein or phloem protein 1 (PP1) and the phl ...
... (Schulz, 1990) and seedless vascular plants. Cucurbits have been used as a model plant for many phloem studies because of their distinctive phloem anatomy and prolific vascular exudation. In Cucurbita spp., two predominant P-proteins, the phloem filament protein or phloem protein 1 (PP1) and the phl ...
Protein translocation pathways across the inner and outer
... Tom20 and Tom70 act as receptors for the precursor proteins20. Tom22 has various roles including receptor functions21, helps in passage of precursor proteins from the receptors to pore22, and binds precursors at trans site23. Tom40 forms poreforming component of the complex and is essential for cell ...
... Tom20 and Tom70 act as receptors for the precursor proteins20. Tom22 has various roles including receptor functions21, helps in passage of precursor proteins from the receptors to pore22, and binds precursors at trans site23. Tom40 forms poreforming component of the complex and is essential for cell ...
Cyclol
The cyclol hypothesis is the first structural model of a folded, globular protein. It was developed by Dorothy Wrinch in the late 1930s, and was based on three assumptions. Firstly, the hypothesis assumes that two peptide groups can be crosslinked by a cyclol reaction (Figure 1); these crosslinks are covalent analogs of non-covalent hydrogen bonds between peptide groups. These reactions have been observed in the ergopeptides and other compounds. Secondly, it assumes that, under some conditions, amino acids will naturally make the maximum possible number of cyclol crosslinks, resulting in cyclol molecules (Figure 2) and cyclol fabrics (Figure 3). These cyclol molecules and fabrics have never been observed. Finally, the hypothesis assumes that globular proteins have a tertiary structure corresponding to Platonic solids and semiregular polyhedra formed of cyclol fabrics with no free edges. Such ""closed cyclol"" molecules have not been observed either.Although later data demonstrated that this original model for the structure of globular proteins needed to be amended, several elements of the cyclol model were verified, such as the cyclol reaction itself and the hypothesis that hydrophobic interactions are chiefly responsible for protein folding. The cyclol hypothesis stimulated many scientists to research questions in protein structure and chemistry, and was a precursor of the more accurate models hypothesized for the DNA double helix and protein secondary structure. The proposal and testing of the cyclol model also provides an excellent illustration of empirical falsifiability acting as part of the scientific method.