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regulation-2013
regulation-2013

... 8-Regulation by protein stability •Ubiquitin-dependent proteolysis. Cyclins control of cell cycle. • Protein molecule is tagged for degradation by attachment of a 20 kDa protein, ubiquitin ...
Polypeptide Chain Synthesis: A Paper Simulation
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... Involves two amino acids.  Involves a dehydration synthesis.  Involves a chemical reaction that occurs between two specific areas of the amino acid.  Requires an –OH group and an –H from another –OH group ...
Exam II Answer Key
Exam II Answer Key

... sequences are maintained, the resultant protein product will be maintained. Bacterial genes are arranged much closer together on prokaryotic chromosomes when compared to genes on human chromosomes. Provide one advantage and one disadvantage for the extra “space” that is contained within human chromo ...
How are we different? …at the RNA level.
How are we different? …at the RNA level.

... • In fact (in 2002), there was only one well understood biochemical difference, – A 92 bp deletion in a gene that codes for a hydroxylase, results in an un-hydroxylated secretion protein in our immune system. ...
pGLO Transformation Lab Background Information Introduction to
pGLO Transformation Lab Background Information Introduction to

... (catabolism) of food are good examples of highly regulated genes. For example, the sugar arabinose is both a source of energy and a source of carbon. E. coli bacteria produce three enzymes (proteins) needed to digest arabinose as a food source. The genes which code for these enzymes are not expresse ...
GATTACA Analysis Questions
GATTACA Analysis Questions

Chapters 13-16, Molecular Genetics
Chapters 13-16, Molecular Genetics

... or off followed by others in an orderly progression of events 3. Hierarchy of “gene control” exists in complex eukaryotes a. Homeotic genes ...
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... 2. What does the normal (functional) version of the gene do in the cell? 3. What does the mutated version of the gene do that contributes to cancer? 4. What cancers is the mutated version of the gene associated with? 5. What are the symptoms and physiological problems of this cancer? 6. What signali ...
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Adrenocorticotropic hormone deficiency associated with combined

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... MONOSOMY WHICH EXISTS IN HUMANS. • 98% of these fetuses die prior to birth ...
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The Role of RNA
The Role of RNA

...  In a substitution, one base is changed to a different base, which may affect only a single amino acid and have no effect at all.  In insertions and deletions, one base is inserted or removed from the DNA sequence. Insertions and deletions are called frameshift mutations because they shift the “re ...
Cloning and PCR File
Cloning and PCR File

Big, strong, fast, and aggressive
Big, strong, fast, and aggressive

... Biotechnology • Biotechnology - when scientists purposely change the genetic makeup of an organism (Ex: introduce a mutation) • Used in agriculture and medicine • Bacterial mutations A strain of bacteria has been developed that can digest oil to help clean oil spills Scientists are trying to produ ...
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bYTEBoss 140-S08

... (one “gene”) provided 7 and 23 don't meiotically map as large deletions ...
B2.10a - Science @ St John`s
B2.10a - Science @ St John`s

... You are going to build an amino acid chain starting from the DNA code. Remember that in complementary base pairing, A (adenine) pairs with T (thymine), and C (cytosine) pairs with G (guanine). Also remember that in RNA the base T is replaced by U (uracil). Here is a sequence of bases from the coding ...
Nucliec acids and dna review
Nucliec acids and dna review

... Where in the cell does transcription take place? A. in the nucleus B. on ribosomes in the cytoplasm C. in Golgi bodies D. on the nucleosomes Where in the cell does translation take place? A. in the nucleus B. on ribosomes in the cytoplasm C. in Golgi bodies D. on the nucleosomes How many codons are ...
Macro-molecule study guide / worksheet
Macro-molecule study guide / worksheet

... Enzymes - with few exceptions, they are proteins Catalyst - substance that speeds up the rate of a chemical reaction. Living organisms contain enzymes, which are catalysts Characteristics of Enzymes  Are not used up in a reaction  Combine with substrates  Speed up the rate of a reaction Enzymes a ...
Cloning
Cloning

... Contain an oriV that allows for high copy number, may have narrow (pUC) or broad (R) host ranges Small – why is this an advantage? Selectable Genes Unique restriction sites May have additional features such as mob sites, RNA polymerase promoters, etc. ...
Biochemistry 462a - Proteins: Primary Sequence
Biochemistry 462a - Proteins: Primary Sequence

... Genomics and Proteomics There is a great of activity directed towards determining the complete sequence of the human genome (genomics) and several other genomes are also being sequenced, e.g., yeast has been done and the fruit fly Drosophila melanogaster will be finished soon. One the complete seque ...
BIOLOGY The tests are based on the knowledge of grammar school
BIOLOGY The tests are based on the knowledge of grammar school

... 7. Transduction is the process by which DNA is transferred from one bacterium to another by: a) cell fusion b) a phage c) isolated nucleus d) single deoxyribonucleotides 8. A phenotype is a) usually determined by two alleles b) independent of genotype c) a synonym for genotype in haploid organisms d ...
Slide 1
Slide 1

... • The marker is a slight, but precise variation in the chemistry of one gene detected in the DNA of the patients’ white blood cells. • Patients were found to be more than three times as likely as non-sufferers to have the variant in the genetic material of their cells. • Question: is this a normal v ...
Biochemistry Jeopardy C.P. Bio.
Biochemistry Jeopardy C.P. Bio.

Concept Check Questions with answers
Concept Check Questions with answers

... Some human genes are too large to be incorporated into bacterial plasmids. Bacterial cells lack the means to process RNA transcripts, and even if the need for RNA processing is avoided by using cDNA, bacteria lack enzymes to catalyze the post-translational processing that many human proteins undergo ...
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Point mutation



A point mutation, or single base modification, is a type of mutation that causes a single nucleotide base change, insertion, or deletion of the genetic material, DNA or RNA. The term frameshift mutation indicates the addition or deletion of a base pair. A point mutant is an individual that is affected by a point mutation.Repeat induced point mutations are recurring point mutations, discussed below.
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