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carbohydrates: monosaccharides. oligo
carbohydrates: monosaccharides. oligo

... The formation of the cyclic form is accompanied by formation of new hydroxyl group which is absent in the open-chain form. It is called hemiacetal hydroxyl group. Its properties differ from the other hydroxyl groups because of two reasons. First of all, it is in equilibrium with the carbonyl group a ...
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CHEM120 - ORGANIC CHEMISTRY WORKSHEET 1
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... Ozonolysis of Alkenes - oxidative cleavage of an alkene to carbonyl compounds (aldehydes and ketones). The and -bonds of the alkene are broken and replaced with C=O double bonds. C=C of aryl rings, CN and C=O do not react with ozone, CC react very slowly with ozone ...
reactions of alcohols with alkenes over an aluminum
reactions of alcohols with alkenes over an aluminum

... Figure 1. Mechanism for the acid-catalyzed reaction of 2-methyl pent-2-ene with alcohols (Al-montmorillonite catalyst). methyl t-butyl ether when using a clay catalyst (Bylina et al.. 1980: Adams et al.. 1981b). At this temperature methanol is the only alcohol to form a di-alkyl ether. whereas Balla ...
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Organic - UCLA Chemistry and Biochemistry
Organic - UCLA Chemistry and Biochemistry

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... reacted With HBr to give (c) which is an isomer of (a). when (a) is reacted with Na metal it give (d), C818 which is different from the compound formed when n-butyl bromide is reacted with Na metal . Give the structural formula of (a) and write the equations. ...
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Reactions of 2, 6-cycloheptadienone and 2, 7

... 1965, Garbisch4 described the preparation of 2,6cycloheptadienone (1), 2,7-~yclooctadienone (2), and other cycloallcadienones from their corresponding cycloallcanones. Although four steps are required in Garbisch's synthesis, they are described thoroughly and the overall yields are good. The reasona ...
Elimination Reactions
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... The substrates that favour E1 reactions are the same that favour SN1 reactions: •A substrate bearing a good leaving group attached to a tetrahedral carbon atom. •A substrate that can form a relatively stable carbocation. The difference between E1 and SN1 reactions is in the type species which reacts ...
Elimination Reactions
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... The substrates that favour E1 reactions are the same that favour SN1 reactions: •A substrate bearing a good leaving group attached to a tetrahedral carbon atom. •A substrate that can form a relatively stable carbocation. The difference between E1 and SN1 reactions is in the type species which reacts ...
Chapter 24. Amines
Chapter 24. Amines

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Chapter 9
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biodiesel production via acid catalysis
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10.3 PREPARATION OF ETHERS

... However, this reaction is much less useful when ammonia is the nucleophile because the initial product, a primary amine, is a stronger base and a stronger nucleophile than is ammonia. Therefore, the primary amine preferentially reacts as the nucleophile, producing a secondary amine as a by-product ( ...
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Manganese-Catalyzed  Carbonylation  of Alkyl  Iodides
Manganese-Catalyzed Carbonylation of Alkyl Iodides

... in Partial Fulfillment for the Degree of Science Masters in Organic Chemistry ...
Amino Alcohol Oxidation with Gold Catalysts: The Effect of Amino
Amino Alcohol Oxidation with Gold Catalysts: The Effect of Amino

< 1 ... 14 15 16 17 18 19 20 21 22 ... 68 >

Baylis–Hillman reaction



The Baylis–Hillman reaction is a carbon-carbon bond forming reaction between the α-position of an activated alkene and an aldehyde, or generally a carbon electrophile. Employing a nucleophilic catalyst, such as tertiary amine and phosphine, this reaction provides a densely functionalized product (e.g. functionalized allyl alcohol in the case of aldehyde as the electrophile). This reaction is also known as the Morita–Baylis–Hillman reaction or MBH reaction. It is named for the Japanese chemist Ken-ichi Morita, the British chemist Anthony B. Baylis and the German chemist Melville E. D. Hillman.DABCO is one of the most frequently used tertiary amine catalysts for this reaction. In addition, nucleophilic amines such as DMAP and DBU as well as phosphines have been found to successfully catalyze this reaction.MBH reaction has several advantages as a useful synthetic method: 1) It is an atom-economic coupling of easily prepared starting materials. 2) Reaction of a pro-chiral electrophile generates a chiral center, therefore an asymmetric synthesis is possible. 3) Reaction products usually contain multiple functionalities in a proximity so that a variety of further transformations are possible. 4) It can employ a nucleophilic organo-catalytic system without the use of heavy metal under mild conditions.Several reviews have been written.
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