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Physiology of the Blood III. White Blood Cells and the Immune
Physiology of the Blood III. White Blood Cells and the Immune

... 2. STRANGER CELLS and MOLECULES (transplantation, allergic reactions) 3. SELF CELLS (autoimmunity, tumor cells) 4. DANGER SIGNALS (e.g., after tissue injury) Enemy in general – e.g., differentiation of bacteria from self cells Enemy specifically – recognition of one particular bacterium or its subty ...
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Genetically Engineered Antibodies
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... They have extensive cytoplasmic domains that interact with intracellular molecules. They consist of polypeptides with variable and constant regions. They are associated with signal transduction molecules at the cell surface. They can interact with peptides derived from non-self antigens. ...
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The Science behind the “Noses are Red” show

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Immunity - CIE Alevel notes!

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immunesystem
immunesystem

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... d. Benedict, C. L. and Kearney, J. F.: Increased junctional diversity in the fetal B cells results in a loss of protective anti-phosphorylcholine antibodies in adult mice. Immunity 10:607-617, 1999 4. Studies from the PI and others described in reference 2.a (above) showed that VH81x, the most DHpro ...
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11.1 HL Immune System Part 1

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Immune System Notes: Part I

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final exam of medical immunology
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Introduction to Analytical Techniques
Introduction to Analytical Techniques

... - Used to separate proteins based on the nature of the R groups found in their specific amino acid sequence. - Can be used to separate isotypes of the same protein. ii. Ion exchange chromatography - Used to separate proteins or nucleic acids based on their electrical charge. - Frequently used as a p ...
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Monoclonal antibody



Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are made by identical immune cells that are all clones of a unique parent cell, in contrast to polyclonal antibodies which are made from several different immune cells. Monoclonal antibodies have monovalent affinity, in that they bind to the same epitope.Given almost any substance, it is possible to produce monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the non-proprietary drug name ends in -mab (see ""Nomenclature of monoclonal antibodies""), and many immunotherapy specialists use the word mab anacronymically.
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