Metabolism of Lipids
... Physiological effects at very low concentrations Many of their effects mediated by cyclic AMP or calcium second messengers Unlike hormones, not transported in the blood Local mediators that act where synthesized or in adjacent cells ...
... Physiological effects at very low concentrations Many of their effects mediated by cyclic AMP or calcium second messengers Unlike hormones, not transported in the blood Local mediators that act where synthesized or in adjacent cells ...
for students of the Faculty of Medicine
... Some amino acids have two amino groups located at different carbon atoms, a few contain two or even three carboxyl groups. Two amino acids, proline and its hydroxylated derivative - hydroxyproline, have no amino group but an imino group, which is why they are called imino acids. There are more than ...
... Some amino acids have two amino groups located at different carbon atoms, a few contain two or even three carboxyl groups. Two amino acids, proline and its hydroxylated derivative - hydroxyproline, have no amino group but an imino group, which is why they are called imino acids. There are more than ...
Comprehensive Analysis of Hyrdrogen Bonds in Regulatory Protein
... of these bonds involve the protein side-chains and the DNA atoms at the base edges and in the backbone, but interactions that involve the protein backbone are also found. The contacts that involve the DNA backbone are believed to stabilize the complex and to orient the protein against the DNA in a f ...
... of these bonds involve the protein side-chains and the DNA atoms at the base edges and in the backbone, but interactions that involve the protein backbone are also found. The contacts that involve the DNA backbone are believed to stabilize the complex and to orient the protein against the DNA in a f ...
insulin history
... be used to produce recombinant proteins and change the world, there was significant fear from scientists (and the public) about the safety of recombinant DNA technology. In his research, Berg was using a monkey virus that could cause cancer; if he inserted it into bacteria and the bacteria infected ...
... be used to produce recombinant proteins and change the world, there was significant fear from scientists (and the public) about the safety of recombinant DNA technology. In his research, Berg was using a monkey virus that could cause cancer; if he inserted it into bacteria and the bacteria infected ...
Automated extraction of mutation data from the literature: application
... terms with their true contextual meanings. For example, the term ‘T47D’ will be ignored if it is found close to the terms ‘cell line’, ‘tumour’, ‘tumor’ or ‘cancer’. This list will have to be updated manually as other point mutation-like terms are detected in the documents subsequently processed. Ho ...
... terms with their true contextual meanings. For example, the term ‘T47D’ will be ignored if it is found close to the terms ‘cell line’, ‘tumour’, ‘tumor’ or ‘cancer’. This list will have to be updated manually as other point mutation-like terms are detected in the documents subsequently processed. Ho ...
Presentation
... Cells have a set of organelles that are specialized for carrying out one or more vital functions. Proteins must be transported to the correct organelles of a cell to properly perform their functions. Therefore, knowing the subcellular localization is one step towards understanding the functions of p ...
... Cells have a set of organelles that are specialized for carrying out one or more vital functions. Proteins must be transported to the correct organelles of a cell to properly perform their functions. Therefore, knowing the subcellular localization is one step towards understanding the functions of p ...
intermediary metabolism
... Hormones are chemical menagers secreted by different endocrine glands and carried by blood to other tissues or organs, where they may stimulate or inhibit some specific metabolic activity. For e.g. the hormone adrenalin, secreted by the medulla of the adrenal gland, is carried by the blood to the li ...
... Hormones are chemical menagers secreted by different endocrine glands and carried by blood to other tissues or organs, where they may stimulate or inhibit some specific metabolic activity. For e.g. the hormone adrenalin, secreted by the medulla of the adrenal gland, is carried by the blood to the li ...
Chapter 5 The Structure and Function of Large Biological Molecules
... Skill: Knowledge/Comprehension ...
... Skill: Knowledge/Comprehension ...
Chapter 20 Specific Catabolic Pathways: Carbohydrate, Lipid, and
... Nitrogen of Amino Acids -NH2 groups move freely by transamination • Pyridoxal phosphate forms an imine (a C=N group) with the -amino group of an amino acid. • Rearrangement of the imine gives an isomeric imine. • Hydrolysis of the isomeric imine gives an -ketoacid and pyridoxamine. Pyridoxamine t ...
... Nitrogen of Amino Acids -NH2 groups move freely by transamination • Pyridoxal phosphate forms an imine (a C=N group) with the -amino group of an amino acid. • Rearrangement of the imine gives an isomeric imine. • Hydrolysis of the isomeric imine gives an -ketoacid and pyridoxamine. Pyridoxamine t ...
Chapter 2 Immobilization of Enzymes
... chromatography, and biosensors. At the beginning, only immobilized single enzymes were used, after 1970s more complex systems including two-enzyme reactions with cofactor regeneration and living cells were developed. The enzymes can be attached to the support by interactions ranging from reversible ...
... chromatography, and biosensors. At the beginning, only immobilized single enzymes were used, after 1970s more complex systems including two-enzyme reactions with cofactor regeneration and living cells were developed. The enzymes can be attached to the support by interactions ranging from reversible ...
The Role of Nucleoside Diphosphate Kinase in Plant Mitochondria
... organisms from bacteria to human. It was discovered that the genes nm23 and awd, which encode NDPKs are involved in tumour metastasis and Drosophila development, respectively. Thus, NDPK isoforms have been suggested to have specific regulatory functions in addition to their catalytic activity. Plant ...
... organisms from bacteria to human. It was discovered that the genes nm23 and awd, which encode NDPKs are involved in tumour metastasis and Drosophila development, respectively. Thus, NDPK isoforms have been suggested to have specific regulatory functions in addition to their catalytic activity. Plant ...
Enzymes with Molecular Tunnels - Department of Biochemistry | UW
... enhanced about 500-fold when bicarbonate is phosphorylated by ATP to form the carboxy phosphate intermediate. In contrast, there is essentially no effect on the rate of carboxy phosphate formation upon the hydrolysis of glutamine. Thus, it appears that the phosphorylation of bicarbonate serves as th ...
... enhanced about 500-fold when bicarbonate is phosphorylated by ATP to form the carboxy phosphate intermediate. In contrast, there is essentially no effect on the rate of carboxy phosphate formation upon the hydrolysis of glutamine. Thus, it appears that the phosphorylation of bicarbonate serves as th ...
Energy Calculations for 4-Hydroxy-3
... which amino acid residues interact with the hetero compound. The wiring diagram is Figure 5 displayed below. The ligplot of the hetero compound, Figure 6, was also obtained from the PDBSum website. The ligplot is a 2D visualization of the amino acid residues in the protein which interact with the he ...
... which amino acid residues interact with the hetero compound. The wiring diagram is Figure 5 displayed below. The ligplot of the hetero compound, Figure 6, was also obtained from the PDBSum website. The ligplot is a 2D visualization of the amino acid residues in the protein which interact with the he ...
Rooting the Eukaryotic Tree with Mitochondrial and Bacterial
... which are arguably characterized by an ancestral single centriole and cilium, and bikonts with two centrioles and kinetids. Support for this subdivision is further based on the presence of a gene fusion (Stechmann and Cavalier-Smith 2002) and the evolutionary history of myosin forms (Richards and Ca ...
... which are arguably characterized by an ancestral single centriole and cilium, and bikonts with two centrioles and kinetids. Support for this subdivision is further based on the presence of a gene fusion (Stechmann and Cavalier-Smith 2002) and the evolutionary history of myosin forms (Richards and Ca ...
Get PDF - Wiley Online Library
... The effect of natural and lactic acid bacteria (LAB) fermentation processes on metabolite changes in pastes of soybeans and soybean–maize blends was studied. Pastes composed of 100% soybeans, 90% soybeans and 10% maize, and 75% soybeans and 25% maize were naturally fermented (NFP), and were fermente ...
... The effect of natural and lactic acid bacteria (LAB) fermentation processes on metabolite changes in pastes of soybeans and soybean–maize blends was studied. Pastes composed of 100% soybeans, 90% soybeans and 10% maize, and 75% soybeans and 25% maize were naturally fermented (NFP), and were fermente ...
PowerPoint - Scranton Prep Biology
... In straight structures (cellulose), H atoms on one strand can form hydrogen bonds with OH groups on other strands Parallel cellulose molecules held together this way are grouped into microfibrils, which form strong building materials for plants ...
... In straight structures (cellulose), H atoms on one strand can form hydrogen bonds with OH groups on other strands Parallel cellulose molecules held together this way are grouped into microfibrils, which form strong building materials for plants ...
DEPARTMENT OF BIOCHEMISTRY UNIVERSITY OF KERALA
... purification of β- glucuronidase from rat liver lysosomes, enzyme assay, enzyme kinetics, isoenzyme separation- LDH activity, staining- SOD enzyme, immobilization techniques. BCH 531 Cell Biology ...
... purification of β- glucuronidase from rat liver lysosomes, enzyme assay, enzyme kinetics, isoenzyme separation- LDH activity, staining- SOD enzyme, immobilization techniques. BCH 531 Cell Biology ...
Inherited Propionyl
... 108 cells but her cells produced only 0.005 /Amoles "CO2/3 hr per 108 cells, although they oxidized methylmalonate-"C and succinate-1,4-"C normally. Thus, her fibroblasts expressed the same block in propionate oxidation as did her uncultured leukocytes (4). Propionate oxidation by her father's leuko ...
... 108 cells but her cells produced only 0.005 /Amoles "CO2/3 hr per 108 cells, although they oxidized methylmalonate-"C and succinate-1,4-"C normally. Thus, her fibroblasts expressed the same block in propionate oxidation as did her uncultured leukocytes (4). Propionate oxidation by her father's leuko ...
Natural Occurrence and Industrial Applications of d
... vertebrates and invertebrates, and they are involved in hormone synthesis and release [68]. Recently, d-serine has also been shown to be an agonist of NMDA receptors, mediating several important physiological and pathological processes [9] [69] [70]. Moloney has reviewed other d-amino acids which ha ...
... vertebrates and invertebrates, and they are involved in hormone synthesis and release [68]. Recently, d-serine has also been shown to be an agonist of NMDA receptors, mediating several important physiological and pathological processes [9] [69] [70]. Moloney has reviewed other d-amino acids which ha ...
Identification of a structural motif that confers specific interaction with
... nuclear abundance of COP1. The regulated HY5 degradation is likely to be mediated by the 26S proteasome and depends on its interaction with COP1 (Osterlund et al., 2000). Taken together, the results suggest that HY5 interacts with the WD40 domain of COP1 and that the interaction negatively regulates ...
... nuclear abundance of COP1. The regulated HY5 degradation is likely to be mediated by the 26S proteasome and depends on its interaction with COP1 (Osterlund et al., 2000). Taken together, the results suggest that HY5 interacts with the WD40 domain of COP1 and that the interaction negatively regulates ...
Journal of Applied Phycology
... the amino acid sequences reveals an identity of 79%, 70% and 57% with the RecA proteins of Anabaena variabilis,Synechococcus and Escherichiacoli respectively. Alignment of the deduced amino acid sequence revealed that many of the domains and residues assigned functional roles in E. coli RecA are con ...
... the amino acid sequences reveals an identity of 79%, 70% and 57% with the RecA proteins of Anabaena variabilis,Synechococcus and Escherichiacoli respectively. Alignment of the deduced amino acid sequence revealed that many of the domains and residues assigned functional roles in E. coli RecA are con ...
Slides
... (pathway-inputs pwy), (pathway-outputs pwy) Returns all compounds consumed (produced) but not produced (consumed) by pathway (ignores stoichiometry) ...
... (pathway-inputs pwy), (pathway-outputs pwy) Returns all compounds consumed (produced) but not produced (consumed) by pathway (ignores stoichiometry) ...
Colicins produced by the Escherichia fergusonii strains closely
... EF3) was isolated after insertion of Tn7 into the plasmid backbone, resulting in the colicinogenic plasmid DS300. The colicin E1 cea gene encoded by this plasmid had a one-nucleotide replacement (G211A) when compared to cea of pColE1-EF43, resulting in a one-amino acid change (A71T) in colicin E1 pr ...
... EF3) was isolated after insertion of Tn7 into the plasmid backbone, resulting in the colicinogenic plasmid DS300. The colicin E1 cea gene encoded by this plasmid had a one-nucleotide replacement (G211A) when compared to cea of pColE1-EF43, resulting in a one-amino acid change (A71T) in colicin E1 pr ...
Proteolysis
Proteolysis is the breakdown of proteins into smaller polypeptides or amino acids. Uncatalysed, the hydrolysis of peptide bonds is extremely slow, taking hundreds of years. Proteolysis is typically catalysed by cellular enzymes called proteases, but may also occur by intra-molecular digestion. Low pH or high temperatures can also cause proteolysis non-enzymatically.Proteolysis in organisms serves many purposes; for example, digestive enzymes break down proteins in food to provide amino acids for the organism, while proteolytic processing of a polypeptide chain after its synthesis may be necessary for the production of an active protein. It is also important in the regulation of some physiological and cellular processes, as well as preventing the accumulation of unwanted or abnormal proteins in cells. Consequently, dis-regulation of proteolysis can cause diseases, and is used in some venoms to damage their prey.Proteolysis is important as an analytical tool for studying proteins in the laboratory, as well as industrially, for example in food processing and stain removal.