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Fatty Acid Metabolism - chem.uwec.edu
Fatty Acid Metabolism - chem.uwec.edu

... Synthesize Glucose Even though the citric acid cycle intermediate oxaloacetate can be used to synthesize glucose, Acetyl–CoA cannot be used to synthesize oxaloacetate. The two carbons that enter the citric acid cycle as Acetyl–CoA leave as CO2. ...
PPT CH 22
PPT CH 22

The Nucleotide and Derived Amino Acid
The Nucleotide and Derived Amino Acid

... metabolic role of apo-A-1V is unknown, Steinmetz and UterBoth cDNA and genomic clones encoding human apolipoprotein (apo-) A-IV have been isolated and char- mann (5) have demonstrated that human apo-A-IV can be a acterized. Southern blot analyses of apo-A-IV gene- significant activator of 1ecithin:c ...
1. Products of Amino Acid Transamination Name
1. Products of Amino Acid Transamination Name

... melanin, the dark pigment normally present in hair. Decreased tyrosine levels in patients with phenylketonuria result in varying degrees of pigment loss. 12. Role of Cobalamin in Amino Acid Catabolism Pernicious anemia is caused by impaired absorption of vitamin B12. What is the effect of this impai ...
Amino Acids, Then and Now--A Reflection on Sir Hans Krebs
Amino Acids, Then and Now--A Reflection on Sir Hans Krebs

... D -amino acids. He went on to show that there were two different enzymic systems (a “d-amino acid deaminase” and an “l-amino acid deaminase”) on the basis of their differential inhibition by a variety of compounds. He observed that many of the D-amino acids were deaminated much more rapidly than the ...
DNA Methylation of Imprinted Loci on Autosomal Chromosomes and
DNA Methylation of Imprinted Loci on Autosomal Chromosomes and

... subset of genes [1]. In humans, alterations of imprinting patterns gives rise to numerous diseases with well characterized growth phenotypes (Beckwith-Wiedemann and Silver-Russell syndromes), behavioral disorders (Angelman and Prader-Willi syndromes) as well as several types of cancers [2-6]. To dat ...
Protein A gene expression is regulated by DNA supercoiling which
Protein A gene expression is regulated by DNA supercoiling which

... to the stresses encountered. Several environmental factors modify the expression of S. aureus virulence genes. This report shows that the expression of spa (virulence gene encoding the cell-wall-associated protein A) is down-regulated by high osmolarity (1 M NaCl, 1 M KCl or 1 M sucrose) in the wild ...
Functional analysis of plastid DNA replication origins in tobacco by
Functional analysis of plastid DNA replication origins in tobacco by

... B, respectively, is shown on top of the plasmids; regions of homology are indicated by dotted lines. Genes are indicated as open arrows marking the direction of transcription. JSA and JSB denote the border between Inverted Repeat A or B, respectively, and the small single copy region of the plastome ...
Human Heredity - Lyndhurst School
Human Heredity - Lyndhurst School

... What makes us human? We might try to answer that question by looking under the microscope to see what is inside a human cell. Not surprisingly, human cells look much like the cells of other animals. To find what makes us uniquely human, we have to look deeper, into the genetic instructions that build ...
Molecular Docking Studies of Isorhamnetin from Corchorus olitorius
Molecular Docking Studies of Isorhamnetin from Corchorus olitorius

... enzyme (receptor) (figure 5) and showed a binding energy of -7.1Kcal/mol. Caffeic acid, chlorogenic acid and isorhamnetin characterized from Corchorus olitorius plant were also docked with our modeled alpha-amylase and with binding energies of -6.5 Kcal/mol, -7.3 Kcal/mol and -8.5 K/calmol respectiv ...
Powerpoint show
Powerpoint show

... and 643 bp in the mother and 435 and 531 bp in the father. What are all possible fingerprints their children could have and what is the probability of any child getting each combination of alleles? ...
Separation of DNA Restriction Fragments by Ion
Separation of DNA Restriction Fragments by Ion

... range. On this column each sample molecule will interact with a number of the different amino groups. Furthermore, the net charge of the matrix will be strongly pH dependent, highly charged at low pH and little charged at high pH. In chromatofocusing of proteins ...
"Amino Acids of the 21st Century" (7) –The
"Amino Acids of the 21st Century" (7) –The

... group, suggesting that consuming amino acids aids in the recovery of isometric muscle strength. Subjectively, many subjects in the amino acid group also reported reduced muscle soreness and faster recovery from muscle strain. In a similar manner, Nosaka et al. divided 24 healthy male students into t ...
Lecture Note 6
Lecture Note 6

... nucleotide (Figure 38.2). There are 5 different types of nucleobase (cytosine, uracil, thymine, adenine and guanine) attached to the sugar through a N-glycosidic linkage. Uracil is found in RNA whereas thymine is present in the DNA. These nucleotide are abbreviated with the first letter of the base ...
RAPD markers for identifying oil palm (Elaeis guineensis Jacq
RAPD markers for identifying oil palm (Elaeis guineensis Jacq

... comprised the shell-less one (pisifera). The data also provide sufficient evidence for identifying each variety, dura, pisifera and tenera separately as well as the parentals dura and pisifera together. This is the first report of DNA based polymorphism assay to assess the level of variability in oi ...
08_Human_chromosomes(plain)
08_Human_chromosomes(plain)

... While most of our chromosomes are within the nucleus there is also DNA within the mitochondria. The human mtDNA is small, only 16.6 kb, and circular, although it is double stranded like most DNA molecules. It has only 37 genes, 13 of these make mitochondrial proteins and the rest encode tRNAs and rR ...
amino acid 1
amino acid 1

... 2. However, rather than oxidatively deaminating glutamate to form ammonium ion, the a-amino group is transferred to pyruvate to form alanine. 3. The liver takes up the alanine, and converts it back to pyruvate by another transamination reaction. 4. The pyruvate can be used for gluconeogenesis, and t ...
Biology and Society: Marathoners versus Sprinters
Biology and Society: Marathoners versus Sprinters

Gene Section FANCC (Fanconi anaemia complementation group C) Atlas of Genetics and Cytogenetics
Gene Section FANCC (Fanconi anaemia complementation group C) Atlas of Genetics and Cytogenetics

... FANCC join the complex; phosphorylation of FANCA would induce its translocation into the nucleus.This FA complex translocates into the nucleus, where FANCE and FANCF are present; FANCE and FANCF join the complex. The FA complex subsequently interacts with FANCD2 by monoubiquitination of FANCD2 durin ...
BIO 101 Lab OBJECTIVES
BIO 101 Lab OBJECTIVES

... 2. Know how positive and negative controls are used. 3. Know the subunits that make up these 4 groups: carbohydrates (monosaccharides, disaccharides and polysaccharides), proteins, lipids and nucleic acids. 4. Know what the following reagents are used to test for and what a positive result would loo ...
The transcriptional regulator CprK detects chlorination by combining
The transcriptional regulator CprK detects chlorination by combining

... (each with distinct DNA-binding affinities) are populated to significant levels [20]. By contrast, it has been proposed that CprK exhibits either extreme positive or no cooperativity, both effectively leading to an equilibrium between unbound and fully bound CprK [16]. In the latter case, this presu ...
heartsprotein.adv.pdf
heartsprotein.adv.pdf

... Following each amino acid listed, note whether it has a positive or negative charge. ...
105 ACID - DW Brooks
105 ACID - DW Brooks

... was proposed by Br~lnsted and Lowry in 1923. This defmition, which gives a more complete picture of acids and bases, treated an acid as a proton donor and a base as a proton acceptor. An acid-base reaction then is essentially a transfer of protons. During the past several decades other useful defini ...
Emerging real-time PCR applications.
Emerging real-time PCR applications.

Chapter 5 - Biology Junction
Chapter 5 - Biology Junction

... Copyright © 2008 Pearson Education, Inc., publishing as Pearson Benjamin Cummings ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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