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Ch. 2 - The Chemistry of Life
Ch. 2 - The Chemistry of Life

... Atoms are united by chemical bonds During chemical reactions chemical bonds are broken, atoms rearrange, and new chemical bonds form. ◦ A chemical bond is simply the force of attraction ...
Exam 2
Exam 2

... 2. White Leghorn chickens are homozygous for a dominant allele C that produces colored feathers, but also homozygous for the dominant inhibitor allele at another locus (I) that inhibits color formation and prevents expression of C. Another breed (White Wyandottes) are homozygous for both recessive a ...
DNA, The Genetic Material
DNA, The Genetic Material

... and Franklin produced X-rays diffraction pictures of DNA. These images showed DNA to be a helix and regular in width. 6. Jim Watson (American) and Francis Crick (Englishman) – 1953 – discovered the physical structure of DNA. They’re model proposed: a. DNA is a double helix – 2 strands of nucleotides ...
Chapter 8 Lecture Notes
Chapter 8 Lecture Notes

... iii. lac A. Codes for the enzyme transacetylase, which transfers acetyl groups (CH3COO-) to Beta-galactoside sugars. This allows sugars that can’t be metabolized to be exported from the cell instead of accumulating to toxic levels within the cell. c. RNA polymerase can be blocked by repressor protei ...
Within minutes, 2nd Generation ATP® tests answer the question
Within minutes, 2nd Generation ATP® tests answer the question

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A document that can help for writing your lab report: www
A document that can help for writing your lab report: www

...  Plasmids used in genetic engineering are called vectors.  They are used to transfer genes from one organism to another and typically contain a genetic marker conferring a phenotype that can be selected for or against.  Most also contain a polylinker or multiple cloning site (MCS), which is a sh ...
DNA replication limits…
DNA replication limits…

... Although most mutations are believed to be caused by replication errors, they can also be caused by various environmentally induced and spontaneous changes to DNA that occur prior to replication but are perpetuated in the same way as unfixed replication errors. As with replication errors, most envir ...
RNA
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... The Role of RNA The roles played by DNA and RNA molecules in directing protein production are like the two types of plans builders use:  A master plan  A blueprint ...
Cancer results from an accumulation of mutations which
Cancer results from an accumulation of mutations which

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No Slide Title

... Proteins carry out the primary work in a cell, but the set of instructions to make the proteins (the instruction book of life) cannot be encoded by amino acids. Instead,evolution chose nucleotides(DNA, RNA). Why? What are the two requirements of the instruction book of life? 1. The molecular book m ...
Density Gradient Fractionation System
Density Gradient Fractionation System

DNA, RNA, and Proteins
DNA, RNA, and Proteins

... —  Translation: The portion of protein synthesis that takes place at ribosomes and that uses the codons in mRNA molecules to specify the sequence of amino acids in polypeptide chains ...
Genetics Pre/Post Test
Genetics Pre/Post Test

... 11. The different forms of a gene are called _____. 12. Which of the following best describes the chromosomes of eukaryotic cells? a. More-complex eukaryotes have more chromosomes than simpler eukaryotes do b. Different kinds of eukaryotes have different numbers of chromosomes. c. The chromosomes in ...
Structure and Function in Biochemistry
Structure and Function in Biochemistry

... parent and several copies of the plasmid. The information in the structural genes of the plasmid is translated into protein so that the cell synthesizes proteins encoded both by its chromosomal and plasmid DNA. After this heteroduplex plasmid DNA is introduced into a suitable bacterial host, such as ...
NOTE: The provided figures may be useful and beneficial
NOTE: The provided figures may be useful and beneficial

... 3. Imagine that the non-template sequence in question 3 was transcribed instead of the template sequence. Draw the mRNA sequence and translate it using Figure 17.5. (Be sure to pay attention to the 5’ & 3’ ends.) 4. What enables RNA polymerase to start transcribing a gene at the right place on the D ...
News Release
News Release

... How is it possible to do this, to retrace the steps of our ancestors by analysing the DNA of living people? Inheritance is the key. Each of us inherits about six billion letters of DNA from our parents, three billion from each. Made up from four biochemicals; adenine, cytosine, guanine and thymine, ...
Model of Star‐PAP‐mediated cleavage of target RNA. Direct contact
Model of Star‐PAP‐mediated cleavage of target RNA. Direct contact

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國立彰化師範大學100 學年度碩士班招生考試試題
國立彰化師範大學100 學年度碩士班招生考試試題

... (B) inability to synthesize a primer for the continuously made leading strand to be able to fully replicate its template DNA (C) inability to synthesize a primer for the last Okazaki fragment made so that it can fully replicate its template DNA (D) inability to ligate the last Okazaki fragment to th ...
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無投影片標題

... Three essential tools form the basis for studying the function of mammalian genes: 1. Isolation of a mammalian gene ...
Anatomy and Physiology Semester Exam Review Sheet
Anatomy and Physiology Semester Exam Review Sheet

... does in each stage  Cell cycle – what’s occurring at each stage  Binary fission  Crossing over and independent assortment  Chromosomes – what are they and how many humans have Meiosis  Stages of meiosis – and what the cell does in each stage DNA and RNA Synthesis  structure of DNA- nucleotides ...
Overview of Current Research
Overview of Current Research

Proteins Large, complex polymer consists of carbon, oxygen
Proteins Large, complex polymer consists of carbon, oxygen

... Contain detailed instructions to build proteins. Polymers that are made up of monomers called nucleotides. Nucleotides are composed of a sugar, phosphate group and  nitrogen­containing molecule (base) Two general types: RNA and DNA Nucleic acids have just one function­ DNA and RNA work  together to  ...
Conservation of Primary Structure in Bacterial Ribosomal Protein
Conservation of Primary Structure in Bacterial Ribosomal Protein

... Department of Biochemistry, University of Glasgow, Glasgow G12 8QQ, U.K. It is not yet certain whether or not there is a local unwinding of the DNA duplex during transcription by RNA polymerase (Burdon, 1973). It has been shown that various small alkylammonium ions alter both the ‘melting’ point of ...
RNA Transcription
RNA Transcription

... nucleotides together to form a linear nucleic acid chain. Its structure resembles a crab claw. The active site is at the base of the opening and the claws clamp down on the DNA as we shall see. For the sake of simplicity we will begin our discussion of the transcription process in bacteria. ...
Organic Molecules
Organic Molecules

... Polypeptides – Amino acids are assembled into polypeptides by means of peptide bonds. This is formed by a condensation reaction between the COOH groups and the NH2 groups ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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