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DNA Introduction Guide
DNA Introduction Guide

... DNA Introduction This guide coincides with a presentation that will introduce you to the microscopic world of DNA. Without the proper arrangement of DNA, you would not be able to see or comprehend this. 1) What did Mendel’s pea plant experiments and observations allow people to do? ...
Chapter 18 Gene Expression and Protein Synthesis
Chapter 18 Gene Expression and Protein Synthesis

... one of which is the promoter. A promoter is unique to each gene. • There is always a sequence of bases on the DNA strand called an initiation signal. • Promoters also contain consensus sequences, such as the TATA box, in which the two nucleotides T and A are repeated many times. ...
Macromolecules (Chapter 5)
Macromolecules (Chapter 5)

... • The parts of the DNA molecule that make up the polynucleotides that encode for the amino acids can be used to show how closely organisms are related from an evolutionary standpoint. • Molecular biologists can sequence genes and determine how much difference there is between organisms and this help ...
RACC BIO transcription and translation
RACC BIO transcription and translation

... nucleotide bases (A, C, T, and G). • The average gene consists of 3000 bases, but sizes vary greatly, with the largest known human gene being dystrophin at 2.4 million bases. • The total number of genes is estimated at 30,000 • Almost all (99.9%) nucleotide bases are exactly the same in all people. ...
What is a GENE? - West East University
What is a GENE? - West East University

... Molecules combine to form the next level of complexity in biological systems, the biological macromolecules. The structural components of the bodies of all living things are mostly made up of these very large, compounds (though there are lots of other inorganic and smaller organic molecules through ...
BIOCHEMISTRY WEBQUEST
BIOCHEMISTRY WEBQUEST

... http://www2.nl.edu/jste/proteins.htm 1) Proteins are polymers of linked monomers called ___________ ___________. 1pt 2) Click on the “play” button (yellow box) to link the 2 amino acids in the diagram. (a) What kind of a bond is formed? 1 pt (b) What kind of chemical reaction creates this bond? 1 pt ...
Basics of Molecular Cloning
Basics of Molecular Cloning

PCR and Its Applications
PCR and Its Applications

... Ayaz Najafov ...
Genetic Engineering
Genetic Engineering

... 4. Combine the cut pieces of DNA together and ...
DNA Structure and Function
DNA Structure and Function

... bases. (A to T, C to G) Two single strands after separation acts as a template for the assembly of complementary bases in order to create a double helix identical to the original. Three models were proposed after the discovery of double helix by Watson and Crick. o Semiconservative replication: doub ...
4. Transcription in Detail
4. Transcription in Detail

... Positioning is ____________________, because reading frame can _________depending on the base pair from which the ribosome________________. ...
Characterisation of DNA by Agarose Gel Electrophoresis and
Characterisation of DNA by Agarose Gel Electrophoresis and

... Deoxyribonucleic acids (DNA) are the carriers of the genetic material of the cell, i.e. they serve both, the passing on of information to a new cell during mitosis as well as code for anabolic and catabolic processes within the cell. From the fact alone that information about very complex patterns o ...
DNA - TG303
DNA - TG303

... Types of Mutations Base Substitution (point) • Single base in DNA is replaced Missense mutation: substitution results in an amino acid substitution Nonsense mutation: creates a stop codon in the middle of mRNA....preventing synthesis of protein ...
Educational Items Section Nomenclature for the description of mutations and
Educational Items Section Nomenclature for the description of mutations and

... insertion of glutamine serine between lysine (K) in 2 and leucine (L) in 3 ...
Guidelines and Assignments
Guidelines and Assignments

... 1. (MT1) A. How is the 5-mC distributed within the human genome? B. Do all human genes have CpG island at their promoters? C. How bisulfite treatment may affect the CpG methylation status? D. What methods can be used to detect the methylation status of DNA? Please describe at least four different me ...
Methods to analyze RNA expression
Methods to analyze RNA expression

Sec_2_3 Carbon Compunds
Sec_2_3 Carbon Compunds

... Individual nucleotides can be joined to form a nucleic acid  Nucleic acids store and transmit heredity or genetic information ...
Nutrients and the structure of macromolecules File
Nutrients and the structure of macromolecules File

... Naming fats: 1. The fatty acid chains can be different lengths. This is partly how fats get their name i.e. C18 or C12 (Lorenzo’s Oil). 2. These chains can also be saturated with Hydrogen molecules so there are only single bonds between carbon atoms Or……… They can be unsaturated and have double bond ...
Transcription and the control of gene expression
Transcription and the control of gene expression

Reproduction
Reproduction

... A fertilized swine egg photographed at the moment it is microinjected with new genetic material. The vacuum in the large pipette at the bottom anchors the cell while a mixture containing the genetic material is forced through the smaller pipette into one of the egg’s pronuclei. Courtesy of R. E. Ham ...
3.1 Review PBS
3.1 Review PBS

... DNA code affect the shape of a protein? • A mutation is change in one base (point mutation) or bases (frameshift mutation due to addition or deletion of base) of DNA. • This can change the codon, which then can change the amino acid(s). • If an amino acid of one property is replaced with an amino ac ...
Cells Are Made Of Molecules
Cells Are Made Of Molecules

... C. Living cells make a vast number of different _______________________ 1. There are about a ____________________ different kinds of _____________ found in nature. 2. Cells make all of its diverse ______________________ from a small number of ________________________ (40-50) D. The variety of ______ ...
Basics of Chromosomes
Basics of Chromosomes

... life. These are called acquired or sporadic mutations. These mutations can occur due to environmental factors or can occur if a mistake is made as DNA copies itself during cell division. These mutations that occur in cells other than egg or sperm, cannot be passed on to future generations. Two types ...
PCR - share1
PCR - share1

... (E. coli is most common host, but yeasts or other cell types work.) ...
The Operon - dl.edi
The Operon - dl.edi

... its own promoter and operator. In this case, however, the presence of tryptophan in the cell shuts down the operon. When Trp is present, it binds to a site on the Trp repressor and enables the Trp repressor to bind to the operator. When Trp is not present, the repressor leaves its operator, and tran ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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