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Chapter 3
Chapter 3

... Nucleic Acids: Informational Macromolecules That Can Be Catalytic • The linkages that hold the nucleotides in RNA and DNA are called phosphodiester linkages. • These linkages are formed between carbon 3 of the sugar and a phosphate group that is associated with carbon 5 of the sugar. • The backbone ...
Using Parker Brother`s game CLUE to learn about DNA
Using Parker Brother`s game CLUE to learn about DNA

... 1. Describe a crime scenario to the students involving some of the characters from the Parker Brother’s game CLUE. Miss Scarlet was found murdered in the library in the middle of the night by Mrs. White (maid). A candlestick lay near the body in a pool of blood. The list of suspects includes wealthy ...
Lecture 11 - Horizontal Gene Transfer S11 2 slides per page
Lecture 11 - Horizontal Gene Transfer S11 2 slides per page

... Example - Streptococcus pneumoniae (GPC) •Becomes competent in late log phase •Competent cell binds ds DNA •Enzymes cut DNA into smaller fragments (5 - 15 kb) •Single strand is taken up by cell Example - Haemophilus influenzae (GNR) •Cell binds DNA only from related species Artificial competence In ...
CHAPTER 12
CHAPTER 12

... during telophase, vesicles derived from the Golgi apparatus move along microtubules to the middle of the cell where they coalesce, producing a cell plate ...
Chapter 1 The Science of Genetics
Chapter 1 The Science of Genetics

...  Genes are made of nucleic acids  Nucleic acids are made of building blocks called nucleotides  Nucleotides have three components – Sugar molecule (ribose or deoxyribose) – Phosphate molecule – Nitrogen-containing molecule (adenine-A-, guanine-G-, cytosineC-, thymine-T-, uracil-U-) ...
Lecture 11 - Horizontal Gene Transfer Chapt. 8 S11
Lecture 11 - Horizontal Gene Transfer Chapt. 8 S11

... Example - Streptococcus pneumoniae (GPC) •Becomes Becomes competent in late log phase •Competent cell binds ds DNA •Enzymes cut DNA into smaller fragments (5 - 15 kb) •Single strand is taken up by cell Example - Haemophilus influenzae (GNR) •Cell binds DNA only from related species Artificial compet ...
Intelligent DNA Chips: Logical Operation of Gene Expression
Intelligent DNA Chips: Logical Operation of Gene Expression

Click here for the LOs of the first 4 key areas
Click here for the LOs of the first 4 key areas

... The ethical issues of stem cell use and the regulation of their use. (f) Cancer cells divide excessively to produce a mass of abnormal cells (called a tumour). These cells do not respond to regulatory signals and may fail to attach to each other. If the cancer cells fail to attach to each other they ...
PCR and Its Applications
PCR and Its Applications

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DNA damage and repair
DNA damage and repair

... per day. While this constitutes only 0.000165% of the human genome's approximately 6 billion bases (3 billion base pairs), unrepaired lesions in critical genes (such as tumor suppressor genes) can impede a cell's ability to carry out its function and appreciably increase the likelihood of tumor form ...
[ the current understanding of DNA has changed dramatically from
[ the current understanding of DNA has changed dramatically from

... independently being copied directly and translated into its product. More complexity is increasingly discovered, such as effects from neighboring genes that may turn on or off or modify a particular gene’s expression. Finally, DNA is much more dynamic than previously thought. In what was a revolutio ...
Name Date Period ______ Chapter 3 and 4 Study Points Discuss
Name Date Period ______ Chapter 3 and 4 Study Points Discuss

... DNA is composed of sugars, phosphates, and nitrogen bases. The nitrogen bases pair up (A with T and T with A) (C with G and G with C). In DNA replication, an enzyme unzips the DNA, free nitrogen bases with sugars and phosphates attached find their match, and an enzyme zips them back up. The result i ...
Protein Structure - Information technology
Protein Structure - Information technology

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... then that the repressor is released from the operator and no longer blocks the attachment of RNA polymerase to the promoter. This allows transcription to begin. ...
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Homework 1 - Berkeley MCB

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Ligation and Transformation

... Process 1. The plasmid vector must be cut with a restriction endonuclease (aka: restriction enzyme) 2. DNA ligase joins the DNA fragment & vector DNA 3. Host cell is made competent so can plasmid can enter 4. Transformed cells are grown on selection media ...
Basics of Molecular biology
Basics of Molecular biology

... Bases • Types:- adenine and guanine (fused five- and sixmembered heterocyclic compounds) – Purines ...
Basics of Molecular biology - Server users.dimi.uniud.it
Basics of Molecular biology - Server users.dimi.uniud.it

... Bases •  Types:- adenine and guanine (fused five- and sixmembered heterocyclic compounds) – Purines ...
dna sequencing lab - Georgia Standards
dna sequencing lab - Georgia Standards

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Transcript
Transcript

... of DNA, essentially like priming an engine with a small amount of gasoline. As we will see, the enzyme that catalyzes the formation of new strands of DNA requires this primer in order to start its work. At the end of DNA replication, however, the RNA primer is degraded and replaced by DNA, through t ...
A. Overview - eweb.furman.edu
A. Overview - eweb.furman.edu

9.9 Forensic Chemistry
9.9 Forensic Chemistry

... (4-i) Outline the structure and composition of DNA Deoxyribonucleic acid is double helix shaped polymer formed by a series of repeating monomers called nucleotides which consist of a sugar molecule (Deoxyribose) attached to a phosphate and a nitrogen base, which is attached to the sugar molecule. In ...
topic B - Institute of Life Sciences
topic B - Institute of Life Sciences

... creating site-specific mutations Oligonucleotide for PCR DNA chip technology ...
PV92 PCR - De Anza
PV92 PCR - De Anza

video slide - BiologyAlive.com
video slide - BiologyAlive.com

... sugar-phosphate sequences called restriction the backbones at each arrow. sites – fragments with “sticky ends” ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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