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How do we know that DNA carries genetic information?
How do we know that DNA carries genetic information?

...  1929 – the chemical components of DNA  1940 – the relationship between genes and proteins  1944 – Genes are made up of DNA  1953 – the double helical structure of the DNA molecule (Watson and Crick)  1957 – the “Central Dogma” and the “sequence hypothesis” (Crick)  1958 – the mechanism of DNA ...
dNTP Mix, 10mM - Thermo Fisher Scientific
dNTP Mix, 10mM - Thermo Fisher Scientific

... E.coli DNA. Quantitative PCR test on ABI Prism 7000 SDS, which uses amplification of E.coli 23S rRNA gene fragment did not detect E.coli DNA. Human DNA. Quantitative PCR test on ABI Prism 7000 SDS, which uses amplification of human genomic DNA fragment did not detect human DNA. ...
Gene Mutations Activity
Gene Mutations Activity

... Background: There are two types of mutations, small­scale gene mutations and large­scale chromosomal mutations.  In this activity you will be learning about gene mutations.  There are two basic types of gene mutations, point (base substitution) and frameshift (insertions and deletions).  In frameshi ...
Biotechnology and Recombinant DNA
Biotechnology and Recombinant DNA

... 2. Anneal: temperature is lowered to 5060°C to allow primers to complementary base pair to the ss template DNA 3. Extend: temperature is raised to 72°C to allow DNA polymerase to synthesize complementary strands Steps repeated 20-30 times Amy Warenda Czura, Ph.D. ...
Slide 1
Slide 1

... • Cells join smaller organic molecules together to form larger molecules. • These larger molecules, macromolecules, may be composed of thousands of atoms and weigh over 100,000 daltons. • The four major classes of macromolecules are: carbohydrates, lipids, proteins, and nucleic acids. ...
Lecture 14: BSCI437 - University of Maryland, College Park
Lecture 14: BSCI437 - University of Maryland, College Park

... • Viral DNA synthesis leads to many cycles of replication and accumulation of large numbers of new viral DNAs. ...
Biology - Raleigh Charter High School
Biology - Raleigh Charter High School

... Heterochromatin is highly condensed form of chromatin and euchromatin is lightly compacted ...
File - Mr Andrews` Science Space!
File - Mr Andrews` Science Space!

... • Cells carry instructions in the nucleus • These instructions are about the whole organism ( all your features) • These instructions are carried on a chemical called DNA • Deoxyribonucleic acid • DNA is a double helix • RNA is the messenger that takes the information outside the nucleus to be trans ...
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Protein Synthesis

... DNA triplets encode for each one of the 20 amino acids that make proteins • During transcription, a DNA triplet will produce an mRNA codon. • During translation, a codon will constitute an amino acid ...
Organic compounds
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2008b(12): Detail the protective and regulatory roles of the liver
2008b(12): Detail the protective and regulatory roles of the liver

... 2008b(12): Detail the protective and regulatory roles of the liver. General: the liver is the largest gland in the body and has multiple functions involved in many essential processes in the body. It is the interface between the gut and the body and therefore has a role in protection from organisms ...
I Will Divide
I Will Divide

... (to the tune of “I Will Survive” by Gloria Gaynor) At first, I was a cell, I was petrified Kept thinking, I’d be stuck in G1 and grow too large in size But then I moved on into S phase and made a copy of my DNA And I grew strong (in G2) And then I got my spindle on! Chorus Oh, no, but I, I will divi ...
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... a. used during DNA replication in the bacterial cell b. used to degrade the bacterial cell's DNA c. intended to destroy foreign DNA that enters the cell d. used to attach pieces of DNA together 49. Which of the following is mismatched? a. bioinformatics—the study of a genome using computer analysis ...
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The Transfer of Genetic Characteristics
The Transfer of Genetic Characteristics

... A chromosome is made up of deoxyribonucleic acid or DNA and proteins. However, Only the DNA is the genetic material. ...
Broomfield High School
Broomfield High School

... 1. Carbon is unparalleled in its ability to form molecules that are large, complex and diverse. Why? a. It has four valence electrons. b. It can form up to 4 covalent bonds. c. These can be single, double, or triple covalent bonds. d. It can form large molecules. e. These molecules can be chains, r ...
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Section F

... Base analogs: direct mutagenesis; Nitrous acid: deaminates C to produce U and guanine analog; Alkylating agents and Arylating agents produce ...
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macromolecules notes

... -primary storage is in adipose tissue (body fat) -primarily made in liver and skeletal muscle -the liver will remove or add glucose to the blood in response to insulin levels: -after a meal, pancreas releases insulin into blood stream -when insulin levels are high, liver removes glucose and makes gl ...
SBI4U: Molecular Genetics Unit Review
SBI4U: Molecular Genetics Unit Review

...  The start codon (AUG) is recognized.  The following components bind: small ribosomal subunit; met-tRNA; large ribosomal subunit 35. Describe the formation of a polypeptide at the ribosome  met-tRNA is at the P site of the ribosome after formation of initiation complex  The ribosome reads the ne ...
AP Biology
AP Biology

... Transfer RNA (tRNA) is the supplier. Transfer RNA delivers amino acids (the building blocks of proteins) to the ribosome to be assembled into a protein. ...
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Chromosomes come in pairs

... DNA that codes for protein is arranged within the gene in a series of exons. The non-coding introns are spliced out during transcription and translation. ...
Sem 2 Bio Review Questions
Sem 2 Bio Review Questions

... spots (Y) is dominant over the gene for red spots and the gene for blue skin color (B) is dominant over the gene for green skin color. What is the probability that red spotted, green skinned offspring will be produced in a cross between a parent that has green skin and is heterozygous (hybrid) for y ...
Bio160 ExIII Sp09
Bio160 ExIII Sp09

... d. turns into water in metabolism e. allows ATP to be made 33. Where in a eukaryotic cell would you expect to find sugar being broken down to make ATP? a. mitochondrion ...
Manipulating DNA
Manipulating DNA

... and animals have been engineered by manipulating their genetic instructions to produce new characteristics. ...
Special enzymes, called restriction enzymes, can cut DNA fragments
Special enzymes, called restriction enzymes, can cut DNA fragments

... the insertion of foreign DNA into a genome. To mix and match genes in animals, often times a viral vector is used to carry the desired gene into the target species. To do so, a piece of the viral DNA is cut out and replaced with the foreign DNA. When the virus infects a cell of the target species, i ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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