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... Examining active genes ◦ Examining active genes in different cells helps scientists to understand how cells function normally and what happens when genes don’t work as they should. ◦ DNA microarray technology enables scientists to study thousands of genes at once to understand ...
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DNA Deoxyribose Nucleic Acid

... A. DNA is made up of nucleotides consisting of the sugar deoxyribose, a phosphate, and one of four nitrogenous bases. B. DNA is made up of nucleotides consisting of the sugar ribose, a carbon ring, and one of four phosphorus bases. C. DNA is made up of proteins consisting of the sugar deoxyribose, a ...
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KS4 Chromosomes, Genes and DNA

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Cell Cycle, DNA, and Protein Synthesis

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I Preparation of Metaphase Chromosomes

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... Eukaryote transcription is monocistronic meaning that only one polypeptide coding region is under control of the promoter. The promoter has several sequences that are similar to the Pribnow and TTGACA boxes in prokaryote promoters. The TATA box (TATAAA) is almost identical to the Pribnow sequence. O ...
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Organizing Protein Synthesis - Dallastown Area School District Moodle

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No Slide Title

... Upstream Elements of Class II • Can be several of these, two that are often found: 1. GC boxes (GGGCGG and CCGCCCC) – Stimulate transcription in either orientation – May be multiple copies – Must be close to TATA box (different from enhancers) – Bind the Sp1 factor 2. CCAAT box – Stimulates transcr ...
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Histology Cell Organelles By Dr. Nand Lal Dhomeja

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... C, H, N, O, P, and S are the most important elements for organisms. Na, K, and Fe are also important. Atoms of elements are almost never found alone, thus they combine to form larger substances called molecules Exs. O2 , F2 or to form compounds Exs. H2O, C6H12O6 . The attraction that hold to atoms t ...
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... (c.) They all contain four interlocking rings.
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... an active site, but an allosteric site. • Binding of a molecule there causes a shape change in the enzyme. This affects its function. ...
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... genetic information carried in molecules of protein or DNA? Two scientists, Alfred Hershey and Martha Chase, devised a simple, yet brilliant, experiment to answer this question. In this activity, you will model their experiment. • Examine the structure of the bacteriophage (also called a phage). Not ...
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Introducing Genetics

... by fluorescent probes attached to the chromosomes. ...
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Creating a Fingerprint from DNA Evidence

... type of cut is referred to as a “sticky end” cut. It is called this because another DNA fragment having the complimentary sequence of exposed bases can attach to the end of the DNA. “Sticky end” cutting enzymes are what are used when attempting to splice a DNA fragment of one organism into the genom ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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