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Biomolecules Discussion
Biomolecules Discussion

... How are polymers broken down?  Hydrolysis—the reverse of dehydration synthesis ...
CHAPTER 17 FROM GENE TO PROTEIN
CHAPTER 17 FROM GENE TO PROTEIN

... Many eukaryotic genes code for a set of closely related polypeptides in a process called alternative splicing. ...
Vocabulary Chapter 8 Heredity and Genetic Variation probability
Vocabulary Chapter 8 Heredity and Genetic Variation probability

... A condition in humans in which the individual contains 47 chromosomes instead of the normal 46. It results in developmental difficulties for the individual. fruit fly A small, rapidly reproducing fly used to study genetics through observable variable traits. recombinant DNA A type of DNA that contai ...
2. Be sure that your exam has 9 pages including this cover sheet.
2. Be sure that your exam has 9 pages including this cover sheet.

... Choose the best answer for the question or the best ending for each statement. Write the letter (A-E) which corresponds to the best answer on the line before the question. (2 pts each) _____1. A key point in Darwin's explanation of evolution is that A. biological structures most likely inherited are ...
DNA Tech WebQuest
DNA Tech WebQuest

... A) About what percent of DNA is unique between individual organisms of the same species? In human DNA, about how many base pairs is this? B) List possible substances found at a crime scene that can be sources for DNA evidence: ...
BIO105 Learning objectives for test 3 Topic: The Cell cycle and
BIO105 Learning objectives for test 3 Topic: The Cell cycle and

... - Define codon, and explain what relationship exists between the linear sequence of codons on mRNA and the linear sequence of amino acids in a polypeptide. - Explain the process of transcription including the three major steps of initiation, elongation, and termination. - Explain how RNA polymerase ...
NAME: Chemistry 232 Analytical Chemistry
NAME: Chemistry 232 Analytical Chemistry

... concentrations of a mixture of CaCl2 and 0.5M phosphoric acid at pH 8. This was a complicated problem because Phosphoric acid is a multiprotic acid (H3A) with Ka’s of 7.11x10-3, 6.32x10-8 and 7.1x10-13. Today you are in a much better position to attack this problem. A. (5 points) What is the predomi ...
Chapter Menu
Chapter Menu

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From DNA to Protein: Gene Expression
From DNA to Protein: Gene Expression

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Biological Catalysts

... covalent bonds (disulphide bridges) & hydrophobic interactions between the amino acid side chains. Enzymes are tertiary structures, and not quaternary as they contain just one polypeptide chain rather than several polypeptides that make up the quaternary structure. ...
Slide 1
Slide 1

... mRNA to cDNA using reverse transcriptase, nucleotides and primers ...
The Nucleic Bases Purines and pyrimidines are nitrogen
The Nucleic Bases Purines and pyrimidines are nitrogen

... nucleotide polymer thus is distinct. We therefore refer to the "5'- end" or the "3'- end" of polynucleotides, the 5'- end being the one with a free or phosphorylated 5'-hydroxyl. The base sequence or primary structure of a polynucleotide can be represented as shown below. The phosphodiester bond is ...
2) Chromatin = uncoiled DNA
2) Chromatin = uncoiled DNA

... 12) _________________________is the process through which mRNA is decoded and forms a protein. 13) _________________________ is the process through which DNA transfers the code to mRNA. 14) ___________________________________ is the sugar in RNA. 15) _______________________________________ is the su ...
Slide 1 - The Fluorescence Foundation
Slide 1 - The Fluorescence Foundation

... Novel fluorescent proteins are incorporated into many of the our popular vectors, designed for: constitutive fusion protein expression in mammalian cells, subcellular localization of organelles or targeting of fusion proteins to a specific location, transcriptional reporting bacterial expression and ...
Regulation of Gene Expression
Regulation of Gene Expression

... Control of Transcription DNA has “on” and “off” switches Activator –protein that binds near gene’s promoter region - allows RNA polymerase to transcribe (allows it to fit) Repressor – protein that binds to DNA and prevents RNA polymerase from binding -coded for by “regulator” gene ...
Macromolecules Notes
Macromolecules Notes

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Making Recombinant DNA
Making Recombinant DNA

Genomics
Genomics

... cytoplasm Translation ...
Genetic engineering
Genetic engineering

... foreign DNA and exactly reproduce itself and the foreign DNA e.g. Bacterial plasmid (loop of DNA found in bacteria). ...
CH 13 Gene Technoogy PPT
CH 13 Gene Technoogy PPT

... Most methods for cloning pieces of DNA in the laboratory share general features, such as the use of bacteria and their plasmids Plasmids are small circular extra-chromosomal DNA molecules that replicate separately (autonomously) from the bacterial chromosome. They are often used as vectors in geneti ...
Hao Nguyen
Hao Nguyen

... non-Watson-Crick basepairs; c) location; and d) why is this necessary (that is, what is the function). (20 points) The Wobble hypothesis (or theory) stated that non-Watson-Crick basepairing occur between the codon and anticodon to explain the fact that fewer (32) tRNA’s (containing anticodon) can re ...
protein - Warren County Schools
protein - Warren County Schools

... •A three-letter code is used because there are 20 different amino acids that are used to make proteins. •If a two-letter code were used there would not be enough codons to select all 20 amino acids. •That is, there are 4 bases in RNA, so 42 (4x 4)=16; where as 43 (4x4x4)=64. ...
Table of Contents - Baton Rouge Community College
Table of Contents - Baton Rouge Community College

... Learning Outcomes: Upon successful completion of this course, the students will be able to: 1. Demonstrate knowledge of genetic principles and problem solving skills. 2. Relate an organism’s genotype to its phenotype. 3. Explain basic techniques used for genetic manipulation and procedures used to i ...
letters The homing endonuclease I-CreI uses three metals
letters The homing endonuclease I-CreI uses three metals

... numbered consistently with the corresponding PDB files and are shown in blue with the exception of the proposed nucleophilie water molecule (orange 24) in the top panel. Bond distances are given in Å. All direct contacts between the bound metal ions and protein side chains and water molecules and th ...
Nucleic Acids and Chromatin
Nucleic Acids and Chromatin

... Understand how modification of chromatin structure can lead to epigenetic inheritance. Supplementary materials: These can be found on the Molecular basis of Medicine web site, I. Nucleic acid structure A. Chemical structure and nomenclature of the nucleotides. 1. DNA and RNA are polymers of nucleoti ...
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Nucleic acid analogue



Nucleic acid analogues are compounds which are analogous (structurally similar) to naturally occurring RNA and DNA, used in medicine and in molecular biology research.Nucleic acids are chains of nucleotides, which are composed of three parts: a phosphate backbone, a pucker-shaped pentose sugar, either ribose or deoxyribose, and one of four nucleobases.An analogue may have any of these altered. Typically the analogue nucleobases confer, among other things, different base pairing and base stacking properties. Examples include universal bases, which can pair with all four canonical bases, and phosphate-sugar backbone analogues such as PNA, which affect the properties of the chain (PNA can even form a triple helix).Nucleic acid analogues are also called Xeno Nucleic Acid and represent one of the main pillars of xenobiology, the design of new-to-nature forms of life based on alternative biochemistries.Artificial nucleic acids include peptide nucleic acid (PNA), Morpholino and locked nucleic acid (LNA), as well as glycol nucleic acid (GNA) and threose nucleic acid (TNA). Each of these is distinguished from naturally occurring DNA or RNA by changes to the backbone of the molecule.In May 2014, researchers announced that they had successfully introduced two new artificial nucleotides into bacterial DNA, and by including individual artificial nucleotides in the culture media, were able to passage the bacteria 24 times; they did not create mRNA or proteins able to use the artificial nucleotides. The artificial nucleotides featured 2 fused aromatic rings.
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